Exercise and circadian rhythm-induced variations in plasma cortisol differentially regulate interleukin-1β (IL-1β), IL-6, and tumor necrosis factor-α (TNFα) production in humans: High sensitivity of TNFα and resistance of IL-6

Journal of Clinical Endocrinology and Metabolism

Volumn 82, Issue 7, 1997, Pages 2182-2191

  DeRijk, Roel ^a,d   Michelson, David ^a   Karp, Brian ^a   Petrides, John ^b   Galliven, Elise ^b   Deuster, Patty ^b   Paciotti, Giulio ^c   Gold, Philip W ^a   Sternberg, Esther M ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^c CytImmune Sciences Inc   (United States)

^d LEIDEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GLUCOCORTICOID; HYDROCORTISONE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; STAPHYLOCOCCUS ENTEROTOXIN A; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; CIRCADIAN RHYTHM; CONTROLLED STUDY; EXERCISE; FEMALE; HUMAN; HUMAN EXPERIMENT; IMMUNE RESPONSE; MALE; NORMAL HUMAN; PRIORITY JOURNAL; STRESS;

ADULT; CIRCADIAN RHYTHM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENTEROTOXINS; EXERCISE; FEMALE; HUMANS; HYDROCORTISONE; INTERLEUKIN-1; INTERLEUKIN-2; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MALE; MIDDLE AGED; SUPERANTIGENS; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

STAPHYLOCOCCUS;

EID: 0030854812     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.82.7.2182     Document Type: Article

References (39)

1. Munck A, Guyer PM, Holbrook NY. 1984 Physiological functions of glucocorticoids in stress and their relation to pharmacological actions. Endocr Rev. 5:25-44.
2. Sternberg EM. 1992 The stress response and the regulation of inflammatory disease. Ann Intern Med. 117:854-866.
3. Sternberg EM, Hill JM, Chrousos GP, et al. 1989 Inflammatory mediator-induced hypothalamic-pituitary-adrenal axis activation is defective in streptococcal cell wall arthritis susceptible Lewis rats. Proc Natl Acad Sci USA. 86:2374-2378.
4. Misiewics B, Poltorak M, Raybourne RB, et al. Intracerebroventricular transplantation of embryonic neuronal tissue from inflammatory resistant into inflammatory susceptible rats suppresses specific components of inflammation. Exp Neurol. In press.
5. Jefferies WM. 1991 Cortisol and immunity. Med Hypotheses. 34:198-208.
6. Yakushiji F, Kita M, Hiroi N, Ueshiba H, Monma I, Miyachi Y. 1995 Exacerbation of rheumatoid arthritis after removal of adrenal adenoma in Cushing's syndrome. Endocr J. 42:219-223.
7. Saldanha C, Tougas G, Grace E. 1986 Evidence for anti-inflammatory effect of normal circulating plasma cortisol. Clin Exp Rheumatol. 4:365-366.
8. de Kloet ER. 1991 Brain corticosteroid receptor balance and homeostatic control. Front Neuroendocrinol. 12:95-164.
9. Kyle SB, Smoak BL, Douglass LW, Deuster PA. 1989 Variability of responses across training levels to maximal treadmill exercise. J Appl Physiol. 67:160-165.
10. Paciotti G, Barron D, Licinio J, Tamarkin L. 1992 Novel immunoassays for the detection of cytokines interleukin-1alpha and interleukin-2 in the circulation of normal subjects. Prog Neuroendocrinimmunol 5:21-30.
11. Oldfield EH, Schulte HM, Chrousos GP, et al. 1986 Corticotropin-releasing hormone (CRH) stimulation in Nelson's syndrome: response of adrenocorticotropin secretion to pulse injection and continuous infusion of CRH. J Clin Endocrinol Metab. 62:1020-1026.
12. Nelson DH, Sandberg AA, Palmer J, Tyler FH. 1952 Blood levels of 17-hydroxycorticosteroids following the administration of adrenal steroids and their relation to levels of circulating leukocytes. J Clin Invest. 31:843-849.
13. Deuster PA, Chrousos GP, Luger A, et al. 1989 Hormonal and metabolic responses of untrained, moderately trained and highly trained men to three exercise intensities. Metabolism. 38:141-148.
14. DeRijk RH, Petrides J, Deuster P, Gold PW, Sternberg EM. 1996 Changes in corticosteroid-sensitivity of peripheral blood lymphocytes following strenuous exercise in humans. J Clin Endocrinol Metab. 81:228-235.
15. Wilckens T. 1995 Glucocorticoid and immune function: physiological relevance and pathogenic potential of hormonal dysfunction. Trends Pharmacol Sci. 16:193-197.
16. Walley ER, Lukacs NW, Standiford TJ, Strieter RM, Kunkel SL. 1996 Balance of inflammatory cytokines related to severity and mortality of murine sepsis. Infect Immun 64:4733-4738.
17. Elliot MJ, Maini RN, Feldmann M, et al. 1993 Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor-α. Arthritis Rheum. 12:1681-1690.
18. Harkness JAL, Richter MB, Panayi GS, et al. 1982 Circadian variation in disease activity in rheumatoid arthritis. Br Med J. 284:551-554.
19. Yamada T, Sato A, Aizuwa T. 1996 Dissociation between serum interleukin-6 rise and other parameters of disease activity in subacute thyroiditis during treatment with corticosteroid. J Clin Endocrinol Metab. 81:577-579.
20. Papankolaou DA, Tsigos C, Oldfield EH, Chrousos GP. 1996 Acute glucocorticoid deficiency is associated with plasma elevations of interleukin-6: does the latter participate in the symtomatology of the steroids withdrawal syndrome and adrenal insufficiency? J Clin Endocrinol Metab. 81:2303-2306.
21. Barber AE, Coyle SM, Marano MA, et al. 1993 Glucocorticoid therapy alters hormonal and cytokine responses to endotoxin in man. J Immunol. 150:1999-2006.
22. Persoons JHA, Schornagel K, Breve J, Berkenbosch F, Kraal G. 1995 Acute stress affects cytokines and nitric oxide production by alveolar macrophages differently. Am J Respir Crit Care Med. 152:619-624.
23. Jabara HH, Loh R, Ramesh N, Vercelli D, Geha RS. 1993 Sequential switching from the u to e via g4 in human B cells stimulated with IL-4 and hydrocortisone. J Immunol. 151:4528-4533.
24. Baumann H, Richards C, Gauldie J. 1987 Interaction among hepatocyte-stimulating factors, interleukin 1 and glucocorticoids for regulation of acute phase plasma proteins in human hepatoma (HepG2) cells. J Immunol. 139:4122-4128.
25. Libert C, Brouckaert P, Fiers W. 1994 Protection by α1-acid glycoprotein against tumor necorosis factor-induced lethality. J Exp Med. 180:1571-1575.
26. Snyers L, De Wit L, Content J. 1990 Glucticorricoid up-regulation of high affinity interleukin 6 receptors on human epithelial cells. Proc Natl Acad Sci USA. 87:2838-2842.
27. Schindlet R, Mancilla J, Endres S, Ghorbani R, Clark SC, Dinarello CA. 1990 Correlations and interactions in the production of interleukin-6 (IL-6), IL-1 and tumor necrosis factor (TNF) in human blood mononuclear cells: IL-6 suppresses IL-1 and TNF. Blood. 75:40-47.
28. Tilg H, Trehu E, Atkins MB, Dinarello CA, Mier JW. 1994 Interleukin-6 (IL-6) as an anti-inflammatory cytokine: induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55. Blood. 83:113-118.
29. Kuhnle U, Keller U, Armanini D, Funder J, Krazowski Z. 1994 Immunofluorescence of mineralocorticoid receptors in peripheral lymphocytes: presence of receptor-like activity in patients with the autosomal dominant form of pseudohypoaldosteronism, and its absence in the recessive form. J Steroid Biochem. 51:267-273.
30. Wiegers GJ, Reul JMHM, Holsboer F, DeKloet ER. 1994 Enhancement of rat splenic lymphocyte mytogenesis after short term preexposure to corticosteroids in vitro. Am J Physiol. 135:2351-2357.
31. DeRijk RH, Van Rooijen N, Tilders FJH, Besedovsky HO, Del Rey A, Berkenbosch F. 1991 Selective depletion of macrophages prevents pituitary-adrenal activation in response to subpyrogenic, but not to pyrogenic, doses of bacterial endotoxin. Endocrinology. 129:330-338.
32. Doherty GM, Jensen JC, Buresh CM, Norton JA. 1992 Hormonal regulation of inflammatory cell cytokine transcript and bioactivity production in response to endotoxin. Cytokine. 4:55-62.
33. Heinrich PC, Castell JV, Andus T. 1990 Interleukin-6 and the acute phase response. Biochem J. 265:621-636.
34. Ottaway CA, Husband AJ. 1994 The influence of neuroendocrine pathways on lymphocyte migration. Immunol Today. 15:511-517.
35. Cassatella M. 1995 The production of cytokines by polymorphonuclear neutrophils. Immunol Today. 16:21-26.
36. Qian Q, Jutial MA, Van Rooijen N, Cutler JE. 1994 Elimination of mouse splenic macrophages correlates with increased susceptibility to experimental disseminated candidiasis. J Immunol. 152:5000-5008.
37. Berczi I. 1994 The role of the growth and lactogenic hormone familie in immune function. Neuroimmunomodulation. 1:201-216.
38. van der Poll T, Coyle SM, Barbosa K, Braxton CC, Lowry SL. 1996 Epinephrine inhibits tumor necrosis factor-α and potentiates interleukin 10 production during human endotoxemia. J Clin Invest. 97:713-719.
39. Elenkov IJ, Papanicolaou D, Wilder RL, Chrousos GP. 1996 Modulatory effects of glucocorticoids and catecholamines on human interleukin-12 and interleukin-10 production: clinical implications. Proc Assoc Am Physicians. 108:1-8.