-
1
-
-
0035703804
-
Synthesis and potential antimicrobial activity of some new compounds containing the pyrazol-3-one moiety
-
1:CAS:528:DC%2BD38XhtFWmtr4%3D
-
Al-Haiza MA, El-Assiery SA, Sayed GH (2001) Synthesis and potential antimicrobial activity of some new compounds containing the pyrazol-3-one moiety. Acta Pharm 51:251-261
-
(2001)
Acta Pharm
, vol.51
, pp. 251-261
-
-
Al-Haiza, M.A.1
El-Assiery, S.A.2
Sayed, G.H.3
-
2
-
-
34547792223
-
A comparative study of capillary zone electrophoresis and pH-potentiometry for determination of dissociation constants
-
1:CAS:528:DC%2BD2sXpt1Kmurw%3D 17537608 10.1016/j.jpba.2007.04.024
-
Andrasi M, Buglyo P, Zekany L, Gaspar A (2007) A comparative study of capillary zone electrophoresis and pH-potentiometry for determination of dissociation constants. J Pharm Biomed Anal 44:1040-1047
-
(2007)
J Pharm Biomed Anal
, vol.44
, pp. 1040-1047
-
-
Andrasi, M.1
Buglyo, P.2
Zekany, L.3
Gaspar, A.4
-
3
-
-
0001148864
-
Antibacterial steroidal alkaloids from Sarcococca saligna
-
10.1021/np970294a
-
Atta UR, Anjum S, Farooq A, Khan MR, Parveen Z, Choudhary MI (1998) Antibacterial steroidal alkaloids from Sarcococca saligna. J Nat Prod 61:202-206
-
(1998)
J Nat Prod
, vol.61
, pp. 202-206
-
-
Atta, U.R.1
Anjum, S.2
Farooq, A.3
Khan, M.R.4
Parveen, Z.5
Choudhary, M.I.6
-
4
-
-
55549091381
-
Synthesis of 16E-[3-methoxy-4-(2-aminoethoxy) benzylidene] androstene derivatives as potent cytotoxic agents
-
1:CAS:528:DC%2BD1cXhtlyiurrF 18694772 10.1016/j.steroids.2008.07.004
-
Bansal R, Guleria S (2008) Synthesis of 16E-[3-methoxy-4-(2-aminoethoxy) benzylidene] androstene derivatives as potent cytotoxic agents. Steroids 73:1391-1399
-
(2008)
Steroids
, vol.73
, pp. 1391-1399
-
-
Bansal, R.1
Guleria, S.2
-
5
-
-
1442326729
-
Antihepatotoxic effect of Nymphaea stellata willd., against carbon tetrachloride-induced hepatic damage in albino rats
-
15036469 10.1016/j.jep.2003.11.020
-
Bhandarkar MR, Khan A (2004) Antihepatotoxic effect of Nymphaea stellata willd., against carbon tetrachloride-induced hepatic damage in albino rats. J Ethnopharmacol 91:61-64
-
(2004)
J Ethnopharmacol
, vol.91
, pp. 61-64
-
-
Bhandarkar, M.R.1
Khan, A.2
-
6
-
-
33748209216
-
Utility of cyanoacetic acid hydrazide in heterocyclic synthesis
-
Bondock S, Tarhoni A El-G, Fadda A A (2006) Utility of cyanoacetic acid hydrazide in heterocyclic synthesis. ARKIVOC (ix) 113-156
-
(2006)
ARKIVOC
, Issue.9
, pp. 113-156
-
-
Bondock, S.1
Fadda, A.A.2
-
7
-
-
84986512474
-
CHARMM: A program for macromolecular energy minimization and dynamics calculations
-
1:CAS:528:DyaL3sXit1aiu7w%3D 10.1002/jcc.540040211
-
Brooks BR, Bruccoleri RE, Olafson BD, States DJ, Swaminathan S, Karplus M (1983) CHARMM: a program for macromolecular energy minimization and dynamics calculations. J Comp Chem 4:187-217
-
(1983)
J Comp Chem
, vol.4
, pp. 187-217
-
-
Brooks, B.R.1
Bruccoleri, R.E.2
Olafson, B.D.3
States, D.J.4
Swaminathan, S.5
Karplus, M.6
-
8
-
-
84879695776
-
By-ways of synthesis of cortisone from hecogenin. Part II. A route to 11-oxygenated compounds through 3β: 20β-diacetoxy-11-bromoallopregnan- 12-one
-
Callow RK, James VHT (1956) By-ways of synthesis of cortisone from hecogenin. Part II. A route to 11-oxygenated compounds through 3β: 20β-diacetoxy-11-bromoallopregnan-12-one. J Chem Soc 4744-4749
-
(1956)
J Chem Soc
, pp. 4744-4749
-
-
Callow, R.K.1
Vht, J.2
-
9
-
-
78149265180
-
Sterols as anticancer agents: Synthesis of ring-B oxygenated steroids, cytotoxic profile, and comprehensive SAR analysis
-
1:CAS:528:DC%2BC3cXht1Gqt7%2FJ 20931970 10.1021/jm1007769
-
Carvalho JFS, Silva MMC, Moreira JN, Simoes S, Melo MLS (2010) Sterols as anticancer agents: synthesis of ring-B oxygenated steroids, cytotoxic profile, and comprehensive SAR analysis. J Med Chem 53:7632-7638
-
(2010)
J Med Chem
, vol.53
, pp. 7632-7638
-
-
Carvalho, J.F.S.1
Silva, M.M.C.2
Moreira, J.N.3
Simoes, S.4
Melo, M.L.S.5
-
10
-
-
0028784203
-
Regulation of cholesterol synthesis in four colonic adenocarcinoma cell lines
-
1:CAS:528:DyaK2MXpvFWlsrc%3D 8614298 10.1007/BF02536608
-
Cerda S, Wilkinson J, Broitman S (1995) Regulation of cholesterol synthesis in four colonic adenocarcinoma cell lines. Lipids 30:1083-1092
-
(1995)
Lipids
, vol.30
, pp. 1083-1092
-
-
Cerda, S.1
Wilkinson, J.2
Broitman, S.3
-
11
-
-
33947455737
-
A study of the mechanism of conversion of acetate to cholesterol via squalene
-
1:CAS:528:DyaG2MXhsVSi 10.1021/ja01120a504
-
Dauben GW, Takemura KH (1953) A study of the mechanism of conversion of acetate to cholesterol via squalene. J Am Chem Soc 75:6302-6304
-
(1953)
J Am Chem Soc
, vol.75
, pp. 6302-6304
-
-
Dauben, G.W.1
Takemura, K.H.2
-
12
-
-
80054945124
-
Synthesis of new 3, 20 bispolyaminosteroid squalamine analogues and evaluation of their antimicrobial activities
-
1:CAS:528:DC%2BC3MXht1ClsLbN 21905738 10.1021/jm200506x
-
Djouhri-Bouktab L, Vidal N, Rolain JM, Brunel JM (2011) Synthesis of new 3, 20 bispolyaminosteroid squalamine analogues and evaluation of their antimicrobial activities. J Med Chem 54:7417-7421
-
(2011)
J Med Chem
, vol.54
, pp. 7417-7421
-
-
Djouhri-Bouktab, L.1
Vidal, N.2
Rolain, J.M.3
Brunel, J.M.4
-
13
-
-
33745110220
-
Tumor pH controls the in vivo efficacy of weak acid and base chemotherapeutics
-
1:CAS:528:DC%2BD28XltVWmsrY%3D 16731760 10.1158/1535-7163.MCT-06-0024
-
Gerweck LE, Vijayappa S, Kozin S (2006) Tumor pH controls the in vivo efficacy of weak acid and base chemotherapeutics. Mol Cancer Ther 5:1275-1279
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 1275-1279
-
-
Gerweck, L.E.1
Vijayappa, S.2
Kozin, S.3
-
15
-
-
20944449560
-
Novel C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens: Synthesis, in vitro biological activity, pharmacokinetics, and antitumor activity in the LAPC4 human prostate cancer xenograft model
-
1:CAS:528:DC%2BD2MXis1Ojs70%3D 15828836 10.1021/jm040202w
-
Handratta VD, Vasaitis TS, Njar VCO, Gediya LK, Kataria R, Chopra P, Newman D Jr, Farquhar R, Guo Z, Qiu Y, Brodie AMH (2005) Novel C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens: synthesis, in vitro biological activity, pharmacokinetics, and antitumor activity in the LAPC4 human prostate cancer xenograft model. J Med Chem 48:2972-2984
-
(2005)
J Med Chem
, vol.48
, pp. 2972-2984
-
-
Handratta, V.D.1
Vasaitis, T.S.2
Njar, V.C.O.3
Gediya, L.K.4
Kataria, R.5
Chopra, P.6
Newman, Jr.D.7
Farquhar, R.8
Guo, Z.9
Qiu, Y.10
Brodie, A.M.H.11
-
16
-
-
0040914011
-
P-σ-π analysis. A method for the correlation of biological activity and chemical structure
-
1:CAS:528:DyaF2cXptF2gsQ%3D%3D 10.1021/ja01062a035
-
Hansch C, Fujita T (1964) p-σ-π analysis. A method for the correlation of biological activity and chemical structure. J Am Chem Soc 86:1616-1626
-
(1964)
J Am Chem Soc
, vol.86
, pp. 1616-1626
-
-
Hansch, C.1
Fujita, T.2
-
17
-
-
0038439594
-
IgE-mediated immediate-type hypersensitivity to the pyrazolone drug propyphenazone
-
1:CAS:528:DC%2BD3sXjs1Cjs78%3D 12704373 10.1067/mai.2003.163
-
Himly M, Jahn-Schmid B, Pittertschatscher K, Bohle B, Grubmayr K, Ferreira F, Ebner H, Ebner C (2003) IgE-mediated immediate-type hypersensitivity to the pyrazolone drug propyphenazone. J Allergy Clin Immunol 111:882-888
-
(2003)
J Allergy Clin Immunol
, vol.111
, pp. 882-888
-
-
Himly, M.1
Jahn-Schmid, B.2
Pittertschatscher, K.3
Bohle, B.4
Grubmayr, K.5
Ferreira, F.6
Ebner, H.7
Ebner, C.8
-
18
-
-
38549141572
-
Cellular cholesterol trafficking and compartmentalization
-
1:CAS:528:DC%2BD1cXovFOguw%3D%3D 18216769 10.1038/nrm2336
-
Ikonen E (2008) Cellular cholesterol trafficking and compartmentalization. Nat Rev Mol Cell Biol 9:125-138
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 125-138
-
-
Ikonen, E.1
-
19
-
-
0031794083
-
New antibacterial steroidal alkaloids from Sarcococca brevifolia
-
1:CAS:528:DyaK1cXntV2ns7s%3D 10.1080/10575639808048277
-
Jayasinghe UL, Nadeem M, Atta R, Choudhary MI, Ratnayake HD, Amtul Z (1998) New antibacterial steroidal alkaloids from Sarcococca brevifolia. Nat Prod Lett 12:103-109
-
(1998)
Nat Prod Lett
, vol.12
, pp. 103-109
-
-
Jayasinghe, U.L.1
Nadeem, M.2
Atta, R.3
Choudhary, M.I.4
Ratnayake, H.D.5
Amtul, Z.6
-
20
-
-
0037434588
-
Structure based de novo design, synthesis, and biological evaluation of nonazole inhibitors specific for lanosterol 14R-demethylase of fungi
-
1:CAS:528:DC%2BD3sXksFCjsQ%3D%3D 12570370 10.1021/jm020362c
-
Ji H, Zhang W, Zhang M, Kudo M, Aoyama Y, Yoshida Y, Sheng C, Song Y, Yang S, Zhou Y, Lu J, Zhu J (2003) Structure based de novo design, synthesis, and biological evaluation of nonazole inhibitors specific for lanosterol 14R-demethylase of fungi. J Med Chem 46:474-485
-
(2003)
J Med Chem
, vol.46
, pp. 474-485
-
-
Ji, H.1
Zhang, W.2
Zhang, M.3
Kudo, M.4
Aoyama, Y.5
Yoshida, Y.6
Sheng, C.7
Song, Y.8
Yang, S.9
Zhou, Y.10
Lu, J.11
Zhu, J.12
-
21
-
-
0028854034
-
Molecular recognition of receptor sites using a genetic algorithm with a description of desolvation
-
1:CAS:528:DyaK2MXjtVKlsbc%3D 7823319 10.1016/S0022-2836(95)80037-9
-
Jones G, Willett P, Glen RC (1995) Molecular recognition of receptor sites using a genetic algorithm with a description of desolvation. J Mol Biol 245:43-53
-
(1995)
J Mol Biol
, vol.245
, pp. 43-53
-
-
Jones, G.1
Willett, P.2
Glen, R.C.3
-
22
-
-
84871459189
-
Synthesis of new potential anticancer agents based on 4-thiazolidinone and oleanane scaffolds
-
1:CAS:528:DC%2BC3MXhsFalt77O 10.1007/s00044-011-9893-9
-
Kaminskyy D, Bednarczyk-Cwynar B, Vasylenko O, Kazakova O, Zimenkovsky B, Zaprutko L, Lesyk R (2012) Synthesis of new potential anticancer agents based on 4-thiazolidinone and oleanane scaffolds. Med Chem Res 21:3568-3580
-
(2012)
Med Chem Res
, vol.21
, pp. 3568-3580
-
-
Kaminskyy, D.1
Bednarczyk-Cwynar, B.2
Vasylenko, O.3
Kazakova, O.4
Zimenkovsky, B.5
Zaprutko, L.6
Lesyk, R.7
-
23
-
-
0030979729
-
Effects of a novel free radical scavenger, MCl-186, on ischemic brain damage in the rat distal middle cerebral artery occlusion model
-
1:CAS:528:DyaK2sXjtFyktLs%3D 9152402
-
Kawai H, Nakai H, Suga M, Yuki S, Watanabe T, Saito KI (1997) Effects of a novel free radical scavenger, MCl-186, on ischemic brain damage in the rat distal middle cerebral artery occlusion model. J Pharmacol Exp Ther 281:921-927
-
(1997)
J Pharmacol Exp Ther
, vol.281
, pp. 921-927
-
-
Kawai, H.1
Nakai, H.2
Suga, M.3
Yuki, S.4
Watanabe, T.5
Saito, K.I.6
-
24
-
-
43049088825
-
Rational design, synthesis, and in vivo evaluation of the antileukemic activity of six new alkylating steroidal esters
-
1:CAS:528:DC%2BD1cXlvVSqur8%3D 18353651 10.1016/j.bmc.2008.03.015
-
Koutsourea AI, Fousteris MA, Arsenou ES, Papageorgiou A, Pairas GN, Nikolaropoulos SS (2008) Rational design, synthesis, and in vivo evaluation of the antileukemic activity of six new alkylating steroidal esters. Bioorg Med Chem 16:5207-5215
-
(2008)
Bioorg Med Chem
, vol.16
, pp. 5207-5215
-
-
Koutsourea, A.I.1
Fousteris, M.A.2
Arsenou, E.S.3
Papageorgiou, A.4
Pairas, G.N.5
Nikolaropoulos, S.S.6
-
25
-
-
34247205206
-
Synthesis of some steroidal oximes, lactams, thiolactams and their antitumor activities
-
10.1016/j.steroids.2007.02.005
-
Krstic'a NM, Bjelakovic′ MS, Zizˇakb Z, Pavlovic MD NM, Juranic′ ZD, Pavlovic′ VD (2007) Synthesis of some steroidal oximes, lactams, thiolactams and their antitumor activities. Steroids 72:406-414
-
(2007)
Steroids
, vol.72
, pp. 406-414
-
-
Krstic'A, N.M.1
Bjelakovic, M.S.2
Zizeakb, Z.3
Pavlovic Md, N.M.4
Juranic, Z.D.5
Pavlovic, V.D.6
-
26
-
-
78049518795
-
Multitargeted natural products evaluation based on biological activity prediction with PASS
-
1:CAS:528:DC%2BC3cXmvFCnur8%3D 10.2174/138161210791164063
-
Lagunin A, Filimonov DA, Borodina YV, Lagunin AA, Kos A (2010) Multitargeted natural products evaluation based on biological activity prediction with PASS. Cur pharm des 16:1703-1717
-
(2010)
Cur Pharm des
, vol.16
, pp. 1703-1717
-
-
Lagunin, A.1
Filimonov, D.A.2
Borodina, Y.V.3
Lagunin, A.A.4
Kos, A.5
-
28
-
-
0031024171
-
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
-
1:CAS:528:DyaK2sXktlKlsQ%3D%3D 10.1016/S0169-409X(96)00423-1
-
Lipinski CA, Lombardo F, Dominy BW, Feeney PJ (1997) Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv Drug Delivery Rev 23:3-25
-
(1997)
Adv Drug Delivery Rev
, vol.23
, pp. 3-25
-
-
Lipinski, C.A.1
Lombardo, F.2
Dominy, B.W.3
Feeney, P.J.4
-
29
-
-
33748249320
-
Structures of biologically active oxysterols determine their differential effects on phospholipid membranes
-
1:CAS:528:DC%2BD28XnvValtr8%3D 16939227 10.1021/bi060540u
-
Massey JB, Pownall HJ (2006) Structures of biologically active oxysterols determine their differential effects on phospholipid membranes. Biochemistry 45:10747-10758
-
(2006)
Biochemistry
, vol.45
, pp. 10747-10758
-
-
Massey, J.B.1
Pownall, H.J.2
-
30
-
-
50949124645
-
The components of wool wax. Part III. 7-Oxocholesterol and the alleged presence of cholestanol
-
10.1039/jr9560001736
-
Millurn AH, Truter EV (1956) The components of wool wax. Part III. 7-Oxocholesterol and the alleged presence of cholestanol. J Chem Soc 341:1736-1739
-
(1956)
J Chem Soc
, vol.341
, pp. 1736-1739
-
-
Millurn, A.H.1
Truter, E.V.2
-
31
-
-
47349093417
-
Discovery of new Gram-negative antivirulence drugs: Structure and properties of novel E coli WaaC inhibitors
-
1:CAS:528:DC%2BD1cXosleqtro%3D 18571407 10.1016/j.bmcl.2008.05.117
-
Moreau F, Desroy N, Genevard JM, Vongsouthi V, Gerusz V, Fralliec GL, Oliveira C, Floquet S, Denis A, Escaich S, Wolf K, Busemann M, Aschenbsenner A (2008) Discovery of new Gram-negative antivirulence drugs: structure and properties of novel E. coli WaaC inhibitors. Bioorg Med Chem Lett 18:4022-4026
-
(2008)
Bioorg Med Chem Lett
, vol.18
, pp. 4022-4026
-
-
Moreau, F.1
Desroy, N.2
Genevard, J.M.3
Vongsouthi, V.4
Gerusz, V.5
Fralliec, G.L.6
Oliveira, C.7
Floquet, S.8
Denis, A.9
Escaich, S.10
Wolf, K.11
Busemann, M.12
Aschenbsenner, A.13
-
32
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
1:STN:280:DyaL2c%2FovFSmtw%3D%3D 6606682 10.1016/0022-1759(83)90303-4
-
Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63
-
(1983)
J Immunol Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
33
-
-
0037404468
-
Selection criteria for drug-like compounds
-
1:CAS:528:DC%2BD3sXjsVWitLY%3D 12647312 10.1002/med.10041
-
Muegge I (2003) Selection criteria for drug-like compounds. Med Res Rev 23:302-321
-
(2003)
Med Res Rev
, vol.23
, pp. 302-321
-
-
Muegge, I.1
-
34
-
-
0002431489
-
Outer Membrane in Escherichia coli and Salmonella
-
F.C. Neidhardt R. Curtis III J.L. Ingraham (eds) ASM Washington, DC
-
Nikaido H (1996) Outer Membrane in Escherichia coli and Salmonella. In: Neidhardt FC, Curtis R III, Ingraham JL (eds) Cellular and molecular biology. ASM, Washington, DC, pp 29-47
-
(1996)
Cellular and Molecular Biology
, pp. 29-47
-
-
Nikaido, H.1
-
35
-
-
67349276613
-
Neferine enhances insulin sensitivity in insulin resistant rats
-
1:CAS:528:DC%2BD1MXnt1Cjtb0%3D 19527823 10.1016/j.jep.2009.04.008
-
Pan Y, Cai B, Wang K, Wang S, Zhou S, Yu X, Xu B, Chen L (2009) Neferine enhances insulin sensitivity in insulin resistant rats. J Ethnopharmacol 124:98-102
-
(2009)
J Ethnopharmacol
, vol.124
, pp. 98-102
-
-
Pan, Y.1
Cai, B.2
Wang, K.3
Wang, S.4
Zhou, S.5
Yu, X.6
Xu, B.7
Chen, L.8
-
36
-
-
69249214194
-
Pharmacophore and docking-based combined in silico study of KDR inhibitors
-
1:CAS:528:DC%2BD1MXhtVKksbjM 19447057 10.1016/j.jmgm.2009.04.006
-
Pasha FA, Muddassar M, Neaz MM, Cho SJ (2009) Pharmacophore and docking-based combined in silico study of KDR inhibitors. J Mol Graph Model 28:54-61
-
(2009)
J Mol Graph Model
, vol.28
, pp. 54-61
-
-
Pasha, F.A.1
Muddassar, M.2
Neaz, M.M.3
Cho, S.J.4
-
37
-
-
34249817878
-
Synthesis and evaluation of new 6-hydroximinosteroid analogs as cytotoxic agents
-
1:CAS:528:DC%2BD2sXmtFOjs70%3D 17531494 10.1016/j.bmc.2007.05.003
-
Poza J, Rega M, Paz V, Alonso B, RodrI'guez J, Salvador N, Ferna'ndez A, Jime'nez C (2007) Synthesis and evaluation of new 6-hydroximinosteroid analogs as cytotoxic agents. Bioorg Med Chem 15:4722-4740
-
(2007)
Bioorg Med Chem
, vol.15
, pp. 4722-4740
-
-
Poza, J.1
Rega, M.2
Paz, V.3
Alonso, B.4
Rodri'Guez, J.5
Salvador, N.6
Ferna'Ndez, A.7
Jime'Nez, C.8
-
38
-
-
13444250951
-
In silico prediction of membrane permeability from calculated molecular parameters
-
1:CAS:528:DC%2BD2MXjtFKksg%3D%3D 15689164 10.1021/jm049661n
-
Refsgaard HH, Jensen BF, Brockhoff PB, Padkjaer SB, Guldbrandt M, Christensen MS (2005) In silico prediction of membrane permeability from calculated molecular parameters. J Med Chem 48:805-811
-
(2005)
J Med Chem
, vol.48
, pp. 805-811
-
-
Refsgaard, H.H.1
Jensen, B.F.2
Brockhoff, P.B.3
Padkjaer, S.B.4
Guldbrandt, M.5
Christensen, M.S.6
-
39
-
-
34249942380
-
2β-(N-substituted piperazino)- 5α-androstane-3α17β- diols: Parallel solid-phase synthesis and antiproliferative activity on human leukemia HL-60 cells
-
1:CAS:528:DC%2BD2sXkt1Oqs7o%3D 17441773 10.1021/cc060098z
-
Roy J, DeRoy P, Poirier D (2007) 2β-(N-substituted piperazino)- 5α-androstane-3α17β-diols: parallel solid-phase synthesis and antiproliferative activity on human leukemia HL-60 cells. J Comb Chem 9:347-358
-
(2007)
J Comb Chem
, vol.9
, pp. 347-358
-
-
Roy, J.1
Deroy, P.2
Poirier, D.3
-
40
-
-
84872556406
-
Anticancer steroids: Linking natural and semi-synthetic compounds
-
1:CAS:528:DC%2BC3sXosVagsw%3D%3D 23151898 10.1039/c2np20082a
-
Salvador JAR, Carvalho JFS, Neves MAC, Silvestre SM, Leitào AJ, Silva MMC, Melo MLS′ (2013) Anticancer steroids: linking natural and semi-synthetic compounds. Nat Prod Rep 30:324-374
-
(2013)
Nat Prod Rep
, vol.30
, pp. 324-374
-
-
Salvador, J.A.R.1
Carvalho, J.F.S.2
Neves, M.A.C.3
Silvestre, S.M.4
Leitào, A.J.5
Silva, M.M.C.6
Melo, M.7
-
41
-
-
34548783757
-
Synthesis of chalcone derivatives on steroidal framework and their anticancer activities
-
1:CAS:528:DC%2BD2sXhtVOit7%2FI 17850837 10.1016/j.steroids.2007.07.012
-
Saxena HO, Faridi U, Kumar JK, Luqman S, Darokar MP, Shanker K, Chanotiya CS, Gupta MM, Negi AS (2007) Synthesis of chalcone derivatives on steroidal framework and their anticancer activities. Steroids 72:892-900
-
(2007)
Steroids
, vol.72
, pp. 892-900
-
-
Saxena, H.O.1
Faridi, U.2
Kumar, J.K.3
Luqman, S.4
Darokar, M.P.5
Shanker, K.6
Chanotiya, C.S.7
Gupta, M.M.8
Negi, A.S.9
-
42
-
-
16544395045
-
5-Arylidene-2(5H)-Furanone derivatives: Synthesis and structure-activity relationship for cytotoxicity
-
Seong BC, Yon K, Yun MY, Byung ZA (2004) 5-Arylidene-2(5H)-Furanone derivatives: synthesis and structure-activity relationship for cytotoxicity. Arch Pharm Res 5:485-494
-
(2004)
Arch Pharm Res
, vol.5
, pp. 485-494
-
-
Seong, B.C.1
Yon, K.2
Yun, M.Y.3
Byung, Z.A.4
-
43
-
-
75849138274
-
Synthesis, antibacterial and antifungal activities of 6, 5 fused steroidal oxazoles in cholestane series
-
1:CAS:528:DC%2BC3cXhvF2ru7Y%3D 20031281 10.1016/j.ejmech.2009.12.004
-
Shamsuzzaman, Khan MS, Alam M, Tabassum Z, Ahmad A, Khan AU (2010) Synthesis, antibacterial and antifungal activities of 6, 5 fused steroidal oxazoles in cholestane series. Eur J Med Chem 45:1094-1097
-
(2010)
Eur J Med Chem
, vol.45
, pp. 1094-1097
-
-
Shamsuzzaman1
Khan, M.S.2
Alam, M.3
Tabassum, Z.4
Ahmad, A.5
Khan, A.U.6
-
44
-
-
84956923364
-
Synthesis, characterization, antimicrobial and anticancer studies of steroidal pyrazolines
-
doi: 10.1016/j.jscs.2012.05.004
-
Shamsuzzaman, Khanam H, Dar AM, Siddiqui N, Rehman S (2012) Synthesis, characterization, antimicrobial and anticancer studies of steroidal pyrazolines. J Saudi Chem Soc. doi: 10.1016/j.jscs.2012.05.004
-
(2012)
J Saudi Chem Soc.
-
-
Shamsuzzaman1
Khanam, H.2
Dar, A.M.3
Siddiqui, N.4
Rehman, S.5
-
45
-
-
84872341480
-
Construction of novel steroidal isoxazolidinone derivatives under Vilsmeier-Haack conditions
-
1:CAS:528:DC%2BC38XhvVyhs7jL 10.1016/j.tetlet.2012.11.105
-
Shamsuzzaman, Khanam H, Mashrai A, Siddiqui N (2013) Construction of novel steroidal isoxazolidinone derivatives under Vilsmeier-Haack conditions. Tetrahedron Lett 54:874-877
-
(2013)
Tetrahedron Lett
, vol.54
, pp. 874-877
-
-
Shamsuzzaman1
Khanam, H.2
Mashrai, A.3
Siddiqui, N.4
-
46
-
-
50549158051
-
Studies on succinate-tetrazolium reductase systems. III. Points of coupling of four different tetrazolium salts
-
1:CAS:528:DyaF2cXlt1Wk 14089413 10.1016/0006-3002(63)90513-4
-
Slater TF, Swyer B, Strauli U (1963) Studies on succinate-tetrazolium reductase systems. III. Points of coupling of four different tetrazolium salts. Biochim Biophys Acta 77:383-393
-
(1963)
Biochim Biophys Acta
, vol.77
, pp. 383-393
-
-
Slater, T.F.1
Swyer, B.2
Strauli, U.3
-
47
-
-
0036790413
-
Consequences of cellular cholesterol accumulation: Basic concepts and physiological implications
-
Tabas I (2002) Consequences of cellular cholesterol accumulation: basic concepts and physiological implications. J Clin Invest 110:905-911
-
(2002)
J Clin Invest
, vol.110
, pp. 905-911
-
-
Tabas, I.1
-
48
-
-
0032500849
-
Interaction with P-glycoprotein and transport of erythromycin, midazolam and ketoconazole in Caco-2 cells
-
1:CAS:528:DyaK1cXmslOgu7c%3D 9822896 10.1016/S0014-2999(98)00607-4
-
Takano M, Hasegawa R, Fukuda T, Yumoto R, Nagai J, Murakami T (1998) Interaction with P-glycoprotein and transport of erythromycin, midazolam and ketoconazole in Caco-2 cells. Eur J Pharmacol 358:289-294
-
(1998)
Eur J Pharmacol
, vol.358
, pp. 289-294
-
-
Takano, M.1
Hasegawa, R.2
Fukuda, T.3
Yumoto, R.4
Nagai, J.5
Murakami, T.6
-
49
-
-
43049118945
-
Chemical synthesis of 2βamino-5 α- Androstane-3α17 β-diol N-derivatives and their antiproliferative effect on HL-60 human leukemia cells
-
1:CAS:528:DC%2BD1cXlvVSqtLs%3D 18375126 10.1016/j.bmc.2008.03.031
-
Thibeault D, Roy J, Roy PD, Poirier D (2008) Chemical synthesis of 2βamino-5 α- androstane-3α17 β-diol N-derivatives and their antiproliferative effect on HL-60 human leukemia cells. Bioorg Med Chem 16:5062-5077
-
(2008)
Bioorg Med Chem
, vol.16
, pp. 5062-5077
-
-
Thibeault, D.1
Roy, J.2
Roy, P.D.3
Poirier, D.4
-
50
-
-
0035147506
-
Prediction of a new drug's potential to cause idiosyncratic reactions
-
1:CAS:528:DC%2BD3MXlvFOltw%3D%3D 11727323
-
Uetrecht J (2001) Prediction of a new drug's potential to cause idiosyncratic reactions. Curr Opin Drug Discov Devel 4:55-59
-
(2001)
Curr Opin Drug Discov Devel
, vol.4
, pp. 55-59
-
-
Uetrecht, J.1
-
51
-
-
0027409501
-
Outer membrane permeability barrier to azithromycin, clarithromycin in Gram-negative enteric bacteria
-
1:CAS:528:DyaK3sXhsVehurg%3D 187668 8383945 10.1128/AAC.37.2.354
-
Vaara M (1993) Outer membrane permeability barrier to azithromycin, clarithromycin in Gram-negative enteric bacteria. Antimicrob Agents Chemother 37:354-356
-
(1993)
Antimicrob Agents Chemother
, vol.37
, pp. 354-356
-
-
Vaara, M.1
-
52
-
-
0037030653
-
Molecular properties that influence the oral bioavailability of drug candidates
-
1:CAS:528:DC%2BD38XjsFCmt7g%3D 12036371 10.1021/jm020017n
-
Veber DF, Johnson SR, Cheng HY, Smith BR, Ward KW, Kapple KD (2002) Molecular properties that influence the oral bioavailability of drug candidates. J Med Chem 45:2615-2623
-
(2002)
J Med Chem
, vol.45
, pp. 2615-2623
-
-
Veber, D.F.1
Johnson, S.R.2
Cheng, H.Y.3
Smith, B.R.4
Ward, K.W.5
Kapple, K.D.6
-
53
-
-
67349159434
-
Cytotoxic effects of oxysterols associated with human diseases: Induction of cell death (apoptosis and/or oncosis), oxidative and inflammatory activities, and phospholipidosis
-
1:CAS:528:DC%2BD1MXmtlOqs7c%3D 19248805 10.1016/j.mam.2009.02.006
-
Vejux A, Lizard G (2009) Cytotoxic effects of oxysterols associated with human diseases: induction of cell death (apoptosis and/or oncosis), oxidative and inflammatory activities, and phospholipidosis. Mol Aspects Med 30:153-170
-
(2009)
Mol Aspects Med
, vol.30
, pp. 153-170
-
-
Vejux, A.1
Lizard, G.2
-
54
-
-
0028922586
-
LIGPLOT: A program to generate schematic diagrams of protein-ligand interactions
-
1:CAS:528:DyaK2MXltVCgtLc%3D 7630882 10.1093/protein/8.2.127
-
Wallace AC, Laskowski RA, Thornton JM (1995) LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions. Protein Eng 8:127-134
-
(1995)
Protein Eng
, vol.8
, pp. 127-134
-
-
Wallace, A.C.1
Laskowski, R.A.2
Thornton, J.M.3
-
55
-
-
80052959925
-
Novel terpene based 1,4,2-dioxazoles: Synthesis, characterization, molecular properties and screening against Entamoeba histolytica
-
1:CAS:528:DC%2BC3MXhtV2rtbnP 10.1016/j.ejmech.2011.06.005
-
Wani MY, Athar F, Salauddin A, Agarwal SM, Azam A, Choi I, Bhat AR (2011) Novel terpene based 1,4,2-dioxazoles: synthesis, characterization, molecular properties and screening against Entamoeba histolytica. Eur J Med Chem 46:4742-4752
-
(2011)
Eur J Med Chem
, vol.46
, pp. 4742-4752
-
-
Wani, M.Y.1
Athar, F.2
Salauddin, A.3
Agarwal, S.M.4
Azam, A.5
Choi, I.6
Bhat, A.R.7
-
56
-
-
0027267309
-
Cytotoxicity of artemisinin-related endoperoxides to ehrlich ascites tumor-cells
-
1:CAS:528:DyaK3sXlslemur4%3D 8350087 10.1021/np50096a007
-
Woerdenbag HJ, Moskal TA, Pras N, Malingre TM, El-Feraly FS, Kampinga HH, Konings AWT (1993) Cytotoxicity of artemisinin-related endoperoxides to ehrlich ascites tumor-cells. J Nat Prod 56:849-856
-
(1993)
J Nat Prod
, vol.56
, pp. 849-856
-
-
Woerdenbag, H.J.1
Moskal, T.A.2
Pras, N.3
Malingre, T.M.4
El-Feraly, F.S.5
Kampinga, H.H.6
Konings, A.W.T.7
-
57
-
-
0037183707
-
Myocardial protection of MCI-186 in rabbit ischemia-reperfusion
-
1:CAS:528:DC%2BD38Xms1ymu7o%3D 12215372 10.1016/S0024-3205(02)01965-3
-
Wu TW, Zeng LH, Wu J, Fung KP (2002) Myocardial protection of MCI-186 in rabbit ischemia-reperfusion. Life Sci 71:2249-2255
-
(2002)
Life Sci
, vol.71
, pp. 2249-2255
-
-
Wu, T.W.1
Zeng, L.H.2
Wu, J.3
Fung, K.P.4
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