Novel terpene based 1,4,2-dioxazoles: Synthesis, characterization, molecular properties and screening against Entamoeba histolytica

European Journal of Medicinal Chemistry

Volumn 46, Issue 9, 2011, Pages 4742-4752

  Younus Wani, Mohmmad ^a   Athar, Fareeda ^a   Salauddin, Attar ^a   Agarwal, Subhash Mohan ^b   Azam, Amir ^a   Choi, Inho ^c   Roouf Bhat, Abdul ^c  

^a JAMIA MILLIA ISLAMIA CENTRAL UNIVERSITY   (India)

^b INSTITUTE OF CYTOLOGY AND PREVENTIVE ONCOLOGY   (India)

^c Yeungnam University   (South Korea)

Author keywords

Anti amoebic activity; Cytotoxicity studies; Dioxazole; Terpene

Indexed keywords

1,4,2 DIOXAZOLE DERIVATIVE; 2 [3 (BENZO[D][1,3]DIOXOL 5 YL) 1,4,2 DIOXAZOL 5 YL] PYRIDINE; 2 [3 (BENZO[D][1,3]DIOXOL 5 YL) 5 METHYL 1,4,2 DIOXAZOL 5 YL] PYRIDINE; 2 [3 METHYL 3 (2,6 DIMETHYLHEPTA 1,5 DIENYL) 1,4,2 DIOXAZOLE 5 YL] PYRIDINE; 2 [5 (2,6 DIMETHYLHEPTA 1,5 DIENYL) 1,4,2 DIOXAZOL 3 YL] PYRIDINE; 2 [5 (BENZO[D][1,3] DIOXOL 5 YL) 1,4,2 DIOXAZOL 3 YL] PYRIDINE; 2 [5 METHYL 3 (2,6 DIMETHYLHEPTA 1,5 DIENYL) 1,4,2 DIOXAZOLE 5 YL] PYRIDINE; 3 (2,6 DIMETHYLHEPTA 1,5 DIENYL) 5 (THIOPHEN 2 YL) 1,4,2 DIOXAZOLE; 3 (BENZO[D][1,3]DIOXOL 5 YL) 5 (FURAN 2 YL) 1,4,2 DIOXAZOLE; 3 (BENZO[D][1,3]DIOXOL 5 YL) 5 (FURAN 2 YL) 5 METHYL 1,4,2 DIOXAZOLE; 3 (BENZO[D][1,3]DIOXOL 5 YL) 5 (THIOPHEN 2 YL) 1,4,2 DIOXAZOLE; 3 (BENZO[D][1,3]DIOXOL 5 YL) 5 METHYL 5 (THIOPHEN 2 YL) 1,4,2 DIOXAZOLE; 3 (BENZO[D][1,3]DIOXOL 6 YL) 5 (2,6 DIMETHYLHEPTA 1,5 DIENYL) 1,4,2 DIOXAZOLE; 3 (FURAN 2 YL) 5 (2,6 DIMETHYLHEPTA 1,5 DIENYL) 1,4,2 DIOXAZOLE; 5 (2,6 DIMETHYLHEPTA 1,5 DIENYL) 3 (THIOPHEN 2 YL) 1,4,2 DIOXAZOLE; 5 (BENZO[D][1,3]DIOXOL 5 YL) 3 (2,6 DIMETHYLHEPTA 1,5 DIENYL) 1,4,2 DIOXAZOLE; 5 (BENZO[D][1,3]DIOXOL 5 YL) 3 (FURAN 2 YL) 1,4,2 DIOXAZOLE; 5 (BENZO[D][1,3]DIOXOL 5 YL) 3 (THIOPHEN 2 YL) 1,4,2 DIOXAZOLE; 5 (FURAN 2 YL) 5 METHYL 3 (2,6 DIMETHYLHEPTA 1,5 DIENYL) 1,4,2 DIOXAZOLE; 5 METHYL 3 (2,6 DIMETHYLHEPTA 1,5 DIENYL) 5 (THIOPHENYL 2 YL) 1,4,2 DIOXAZOLE; ANTIPROTOZOAL AGENT; METRONIDAZOLE; TERPENE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIPROTOZOAL ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL VIABILITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG PENETRATION; DRUG SCREENING; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENTAMOEBA HISTOLYTICA; HEART MUSCLE CELL; IC 50; IN VITRO STUDY; LIPOPHILICITY; NONHUMAN; PHYSICAL CHEMISTRY; PROTON NUCLEAR MAGNETIC RESONANCE; RAT;

ANIMALS; ENTAMOEBA HISTOLYTICA; OXAZOLES; TERPENES;

EID: 80052959925     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.06.005     Document Type: Article

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