Interaction with P-glycoprotein and transport of erythromycin, midazolam and ketoconazole in Caco-2 cells

European Journal of Pharmacology

Volumn 358, Issue 3, 1998, Pages 289-294

  Takano, Mikihisa ^a   Hasegawa, Risa ^a   Fukuda, Takeshi ^a   Yumoto, Ryoko ^a   Nagai, Junya ^a   Murakami, Teruo ^a  

^a HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

Caco 2 cell; Cytochrome P 450 3A; Drug interaction; Intestinal transport; P glycoprotein

Indexed keywords

CYTOCHROME P450; ERYTHROMYCIN; GLYCOPROTEIN P; KETOCONAZOLE; MIDAZOLAM; RHODAMINE 123; VERAPAMIL;

ARTICLE; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG TRANSPORT; EPITHELIUM CELL; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM; PRIORITY JOURNAL;

ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; ARYL HYDROCARBON HYDROXYLASES; BIOLOGICAL TRANSPORT; CACO-2 CELLS; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INHIBITORS; ERYTHROMYCIN; GABA MODULATORS; HUMANS; KETOCONAZOLE; MIDAZOLAM; OXIDOREDUCTASES, N-DEMETHYLATING; P-GLYCOPROTEINS; RHODAMINE 123; SUBSTRATE SPECIFICITY; VASODILATOR AGENTS; VERAPAMIL;

EID: 0032500849     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00607-4     Document Type: Article

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