Synthesis and potential antimicrobial activity of some new compounds containing the pyrazol-3-one moiety

Acta Pharmaceutica

Volumn 51, Issue 4, 2001, Pages 251-261

  Al Haiza, Mohamed Ali ^a   El Assiery, Saied Abdullah ^a   Sayed, Galal Hosni ^a  

^a KING KHALID UNIVERSITY   (Saudi Arabia)

Author keywords

Antimicrobial activity; Pyrazol; Synthesis

Indexed keywords

2,5 DIPHENYL 4 [(3,4,5 TRIMETHOXYPHENYL)METHYLIDENE] 2H PYRAZOL 3 ONE; 3 (4 CHLOROPHENYL) 4,6 DIPHENYL 3,6 DIHYDRO 2H PYRAZOLO[4,3 D]ISOXAZOLE; 4 (4 CHLOROPHENYL) 1,3,5 TRIPHENYL 1,3A,4,5 TETRAHYDROPYRAZOLO[3,4 C]PYRAZOLE; 4 [(4 CHLOROPHENYL) (5 OXO 1,3 DIPHENYL 4,5 DIHYDRO 1H PYRAZOL 4 YL)METHYL] 2,5 DIPHENYL 2,4 DIHYDRO 3H PYRAZOL 3 ONE; 4 [(4 CHLOROPHENYL)METHYLIDENE] 2,5 DIPHENYL 2H PYRAZOL 3 ONE; 4 [2 (4 CHLOROBENZYL) 3 (3,4 DIMETHOXYPHENYL) 3 OXO 1 (3,4,5 TRIMETHOXYPHENYL)PROPYL] 2,5 DIPHENYL 2,4 DIHYDRO 3H PYRAZOL 3 ONE; 4 [3 (3,4 DIMETHOXYPHENYL) 3 (2 PHENYLHYDRAZONO) 1 (3,4,5 TRIMETHOXYPHENYL)PROPYL] 2,5 DIPHENYL 2,4 DIHYDRO 3H PYRAZOL 3 ONE; 4 [3 (3,4 DIMETHOXYPHENYL) 3 (HYDRAZONO) 1 (3,4,5 TRIMETHOXYPHENYL)PROPYL] 2,5 DIPHENYL 2,4 DIHYDRO 3H PYRAZOL 3 ONE; 4 [3 (3,4 DIMETHOXYPHENYL) 3 OXO 1 (3,4,5 TRIMETHOXYPHENYL)PROPYL] 1,3 DIPHENYL 1H PYRAZOL 5 YLACETATE; 4 [3 (3,4 DIMETHOXYPHENYL) 3 OXO 1 (3,4,5 TRIMETHOXYPHENYL)PROPYL] 2,5 DIPHENYL 2,4 DIHYDRO 3H PYRAZOL 3 ONE; ANTIINFECTIVE AGENT; CHALCONE; CYCLOHEXANONE; HYDRAZINE; MALONONITRILE; PYRAZOLONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; ASPERGILLUS OCHRACEUS; BACILLUS CEREUS; BACTERIAL INFECTION; DRUG SYNTHESIS; MYCOSIS; NONHUMAN; PENICILLIUM CHRYSOGENUM; PROTEUS MIRABILIS; SERRATIA MARCESCENS; STAPHYLOCOCCUS AUREUS;

EID: 0035703804     PISSN: 13300075     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Synthesis and characterization of certain new 3-methyl-4-(substituted phenylazo)isoxazol-5-ones and 3-methyl-4-(substituted phenylazo)pyrazol-5-ones as potential antibacterial agents
2. Synthesis of 2-(2-benzimidazolyl)/2-(2-benzothiazolyl)-5-alkyl/aryl-1,2-dihydro-3H- pyrazol-3-one derivatives and their antifungal activities
3. Antiviral activity of certain acylpyrazolones
4. 2-Aryl-6-methyl-3-phenylamino-6,7-dihydropyrano (4,3c) pyrazol-4-(2H)-ones with analgesic activity
5. New potent antihyperglycemic agents in db/db mice: Synthesis and structure activity relationship studies of (4-substituted benzyl) (trifluoromethyl) pyrazoles and -pyrazolones
6. Antiinflammatory pyrazolones and pyrazolidones: A study of their inhibition of 5-beta-dihydrocortisone reduction in rat liver cytosol
7. Effects of electron space structure of pyrazolone derivatives on their anti-inflammatory activity
8. Mutagenicity assay in Salmonella and in vitro sister Chromatid exchange in bone marrow cells of mice for four pyrazolone derivative
9. Synthesis and biological activity of some new diketoamino-5-pyrazolones and diketoamino diphenyl sulfones
10. 3-(Arylamino)-6,7-dihydro-6-methyl-pyrano (4,3-c) pyrazol-4 (1H or 2H)-ones with antipyretic, analgesic, antiarrhythmic, hypotensive and other activities
11. Synthesis and antiplatelet activities of N-arylmethyl-3,4-dimethylpyrano (2,3-c) pyrazol-6-one derivatives
12. 1-(2′,5′-dichloro-4′-sulfophenyl)-3-methyl-4-azo (2″-hydroxy-5″-nitro-3″-sulfonic acid)-5-pyrazolone as spectrophotometric reagent for Cu(II)
13. Dyeing and spectrophotometric determination of Hg(II) with 1-(2′,5′-dichloro-4′-sulfophenyl)-3-methyl-4-azo- (2″-carboxy-4″-sulfonic acid)-5-pyrazolone
14. A new reagent system for spectrophotometric determination of iron in pharmaceutical samples
15. Determination of bacterial sensitivity to antibiotics