Design and synthesis of novel iminothiazinylbutadienols and divinylpyrimidinethiones as ARE inducers

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 3, 2014, Pages 940-943

  Chen, Lin ^a   Magesh, Sadagopan ^a   Wang, Hong ^a   Yang, Chung S ^a,c   Kong, Ah Ng Tony ^a,c   Hu, Longqin ^a,b,c  

^a RUTGERS UNIVERSITY   (United States)

^b SHANXI MEDICAL UNIVERSITY   (China)

^c RUTGERS CANCER INSTITUTE OF NEW JERSEY   (United States)

Author keywords

Anti inflammatory agents; ARE induction; Curcumin; Divinylpyrimidinethiones; Iminothiazinylbutadienols

Indexed keywords

ANTIINFLAMMATORY AGENT; CURCUMIN; CYTOTOXIC AGENT; DIKETONE; DIVINYLPYRIMIDINETHIONE DERIVATIVE; GLUTATHIONE; HETEROCYCLIC COMPOUND; IMINOTHIAZINYLBUTADIENOL DERIVATIVE; ISOTHIOCYANIC ACID DERIVATIVE; PYRIMIDINE DERIVATIVE; SULFORAPHANE; THIOUREA DERIVATIVE; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ANTIOXIDANT ASSAY; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CANCER INHIBITION; CELL GROWTH; CONTROLLED STUDY; CYTOTOXICITY; DRUG DESIGN; DRUG SYNTHESIS; LUCIFERASE ASSAY; MICHAEL ADDITION; MOLECULAR STABILITY; NUCLEOPHILICITY; STRUCTURE ACTIVITY RELATION;

ANTI-INFLAMMATORY AGENTS; ARE INDUCTION; CURCUMIN; DIVINYLPYRIMIDINETHIONES; IMINOTHIAZINYLBUTADIENOLS;

ANTIOXIDANT RESPONSE ELEMENTS; CURCUMIN; DRUG DESIGN; ISOTHIOCYANATES; MOLECULAR STRUCTURE; PYRIMIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; THIADIAZINES; THIONES; THIOUREA;

EID: 84893673021     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.12.072     Document Type: Article

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