Curcumin analog cytotoxicity against breast cancer cells: exploitation of a redox-dependent mechanism

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 23, 2009, Pages 6627-6631

  Sun, Aiming ^a   Lu, Yang J ^a   Hu, Haipeng ^a   Shoji, Mamoru ^a   Liotta, Dennis C ^a   Snyder, James P ^a  

^a EMORY UNIVERSITY   (United States)

Author keywords

Anti cancer; Curcumin analogs; Glutathione; Pro drug

Indexed keywords

ANTINEOPLASTIC AGENT; CURCUMIN; CURCUMIN DERIVATIVE; CYSTEINE; DIPEPTIDE; GLUTATHIONE; UNCLASSIFIED DRUG; WATER;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CELL KILLING; CHEMICAL REACTION; CONTROLLED STUDY; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG SOLUBILITY; DRUG STABILITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYDROLYSIS; IC 50; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MICHAEL ADDITION; OXIDATION REDUCTION REACTION; PHOTOSENSITIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; ROOM TEMPERATURE;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CURCUMIN; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; STEREOISOMERISM;

EID: 71749096442     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.10.023     Document Type: Article

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