Mechanism of the dihydroorotase reaction

Biochemistry

Volumn 43, Issue 51, 2004, Pages 16285-16292

  Porter, Tamiko N ^a   Li, Yingchun ^a   Raushel, Frank M ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CADMIUM; HYDROLYSIS; PH EFFECTS; PROTEINS; X RAYS;

APOENZYME; CARBAMOYL ASPARTATE; DIHYDROOROTASE (DHO); X-RAY CRYSTAL STRUCTURES;

ENZYME KINETICS;

AMIDE; APOENZYME; ARGININE; ASPARAGINE; ASPARTIC ACID; BICARBONATE; CADMIUM; CARBOXYLIC ACID; COBALT; DIHYDROOROTASE; DIVALENT CATION; ENZYME; HISTIDINE; HYDROGEN; HYDROXIDE; METAL; METAL ION; OROTIC ACID DERIVATIVE; PROTEIN; PROTON; PYRIMIDINE NUCLEOTIDE; SOLVENT; WATER; ZINC;

ARTICLE; BIOSYNTHESIS; CATALYSIS; CRYSTAL STRUCTURE; ELECTRICITY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME MECHANISM; GENE; HYDROGEN BOND; HYDROLYSIS; NONHUMAN; PH; POLYMERASE CHAIN REACTION; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN PURIFICATION; SITE DIRECTED MUTAGENESIS;

DEUTERIUM; DIHYDROOROTASE; ESCHERICHIA COLI; HYDROGEN-ION CONCENTRATION; KINETICS; MUTAGENESIS, SITE-DIRECTED; OROTIC ACID; SPECTROPHOTOMETRY; SULFUR; ZINC;

EID: 11144301188     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi048308g     Document Type: Article

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