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Volumn 8, Issue 12, 2013, Pages

Clinical significance of keap1 and Nrf2 in oral squamous cell carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGENS, CD147; CARCINOMA, SQUAMOUS CELL; CLUSTER ANALYSIS; CYCLOPHILIN A; GENE EXPRESSION PROFILING; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHATIC METASTASIS; MOUTH NEOPLASMS; NEOPLASM GRADING; NEOPLASM STAGING; NF-E2-RELATED FACTOR 2; PATIENT OUTCOME ASSESSMENT; PEROXIREDOXIN VI; PROGNOSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 84893559180     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0083479     Document Type: Article
Times cited : (54)

References (27)
  • 3
    • 67549084381 scopus 로고    scopus 로고
    • Superoxide is the major reactive oxygen species regulating autophagy
    • Chen Y, Azad MB, Gibson SB (2009) Superoxide is the major reactive oxygen species regulating autophagy. Cell Death Differ 16: 1040-1052.
    • (2009) Cell Death Differ , vol.16 , pp. 1040-1052
    • Chen, Y.1    Azad, M.B.2    Gibson, S.B.3
  • 4
    • 33846117134 scopus 로고    scopus 로고
    • The signaling mechanism of ROS in tumor progression
    • Wu WS (2006) The signaling mechanism of ROS in tumor progression. Cancer Metastasis Rev 25: 695-705.
    • (2006) Cancer Metastasis Rev , vol.25 , pp. 695-705
    • Wu, W.S.1
  • 6
    • 84868249403 scopus 로고    scopus 로고
    • Genetic polymorphisms and protein expression of NRF2 and Sulfiredoxin predict survival outcomes in breast cancer
    • Hartikainen JM, Tengstrom M, Kosma VM, Kinnula VL, Mannermaa A, et al. (2012) Genetic polymorphisms and protein expression of NRF2 and Sulfiredoxin predict survival outcomes in breast cancer. Cancer Res 72: 5537-5546.
    • (2012) Cancer Res , vol.72 , pp. 5537-5546
    • Hartikainen, J.M.1    Tengstrom, M.2    Kosma, V.M.3    Kinnula, V.L.4    Mannermaa, A.5
  • 7
    • 84862779635 scopus 로고    scopus 로고
    • Targeted inhibition of tumor proliferation, survival, and metastasis by pentacyclic triterpenoids: Potential role in prevention and therapy of cancer
    • Shanmugam MK, Nguyen AH, Kumar AP, Tan BK, Sethi G (2012) Targeted inhibition of tumor proliferation, survival, and metastasis by pentacyclic triterpenoids: potential role in prevention and therapy of cancer. Cancer Lett 320: 158-170.
    • (2012) Cancer Lett , vol.320 , pp. 158-170
    • Shanmugam, M.K.1    Nguyen, A.H.2    Kumar, A.P.3    Tan, B.K.4    Sethi, G.5
  • 8
    • 67649959800 scopus 로고    scopus 로고
    • Increased BTB-Kelch type substrate adaptor protein immunoreactivity associates with advanced stage and poor differentiation in renal cell carcinoma
    • Ronkainen H, Vaarala MH, Kauppila S, Soini Y, Paavonen TK, et al. (2009) Increased BTB-Kelch type substrate adaptor protein immunoreactivity associates with advanced stage and poor differentiation in renal cell carcinoma. Oncol Rep 21: 1519-1523.
    • (2009) Oncol Rep , vol.21 , pp. 1519-1523
    • Ronkainen, H.1    Vaarala, M.H.2    Kauppila, S.3    Soini, Y.4    Paavonen, T.K.5
  • 9
    • 84862818295 scopus 로고    scopus 로고
    • Association of increased ligand cyclophilin A and receptor CD147 with hypoxia, angiogenesis, metastasis and prognosis of tongue squamous cell carcinoma
    • Huang C, Sun Z, Sun Y, Chen X, Zhu X, et al. (2012) Association of increased ligand cyclophilin A and receptor CD147 with hypoxia, angiogenesis, metastasis and prognosis of tongue squamous cell carcinoma. Histopathology 60: 793-803.
    • (2012) Histopathology , vol.60 , pp. 793-803
    • Huang, C.1    Sun, Z.2    Sun, Y.3    Chen, X.4    Zhu, X.5
  • 10
    • 79959693689 scopus 로고    scopus 로고
    • Overexpression of thioredoxin system proteins predicts poor prognosis in patients with squamous cell carcinoma of the tongue
    • Zhu X, Huang C, Peng B (2011) Overexpression of thioredoxin system proteins predicts poor prognosis in patients with squamous cell carcinoma of the tongue. Oral Oncol 47: 609-614.
    • (2011) Oral Oncol , vol.47 , pp. 609-614
    • Zhu, X.1    Huang, C.2    Peng, B.3
  • 11
    • 79952595142 scopus 로고    scopus 로고
    • Increased expression of peroxiredoxin 6 and cyclophilin A in squamous cell carcinoma of the tongue
    • Huang CF, Sun ZJ, Zhao YF, Chen XM, Jia J, et al. (2011) Increased expression of peroxiredoxin 6 and cyclophilin A in squamous cell carcinoma of the tongue. Oral Dis 17: 328-334.
    • (2011) Oral Dis , vol.17 , pp. 328-334
    • Huang, C.F.1    Sun, Z.J.2    Zhao, Y.F.3    Chen, X.M.4    Jia, J.5
  • 12
    • 84872714824 scopus 로고    scopus 로고
    • CD147-dependent heterogeneity in malignant and chemoresistant properties of cancer cells
    • Dai L, Guinea MC, Slomiany MG, Bratoeva M, Grass GD, et al. (2013) CD147-dependent heterogeneity in malignant and chemoresistant properties of cancer cells. Am J Pathol 182: 577-585.
    • (2013) Am J Pathol , vol.182 , pp. 577-585
    • Dai, L.1    Guinea, M.C.2    Slomiany, M.G.3    Bratoeva, M.4    Grass, G.D.5
  • 13
    • 33646346876 scopus 로고    scopus 로고
    • Cyclophilin A is overexpressed in human pancreatic cancer cells and stimulates cell proliferation through CD147
    • DOI 10.1002/cncr.21862
    • Li M, Zhai Q, Bharadwaj U, Wang H, Li F, et al. (2006) Cyclophilin A is overexpressed in human pancreatic cancer cells and stimulates cell proliferation through CD147. Cancer 106: 2284-2294. (Pubitemid 43673252)
    • (2006) Cancer , vol.106 , Issue.10 , pp. 2284-2294
    • Li, M.1    Zhai, Q.2    Bharadwaj, U.3    Wang, M.4    Li, F.5    Fisher, W.E.6    Chen, C.7    Yao, Q.8
  • 14
    • 84866918126 scopus 로고    scopus 로고
    • Chemopreventive and chemotherapeutic actions of mTOR inhibitor in genetically defined head and neck squamous cell carcinoma mouse model
    • Sun ZJ, Zhang L, Hall B, Bian Y, Gutkind JS, et al. (2012) Chemopreventive and chemotherapeutic actions of mTOR inhibitor in genetically defined head and neck squamous cell carcinoma mouse model. Clin Cancer Res 18: 5304-5313.
    • (2012) Clin Cancer Res , vol.18 , pp. 5304-5313
    • Sun, Z.J.1    Zhang, L.2    Hall, B.3    Bian, Y.4    Gutkind, J.S.5
  • 16
    • 9444225935 scopus 로고    scopus 로고
    • Java Treeview-extensible visualization of microarray data
    • Saldanha AJ (2004) Java Treeview-extensible visualization of microarray data. Bioinformatics 20: 3246-3248.
    • (2004) Bioinformatics , vol.20 , pp. 3246-3248
    • Saldanha, A.J.1
  • 17
    • 33748255958 scopus 로고    scopus 로고
    • Increased expression of nuclear factor E2 p45-related factor 2 (NRF2) in head and neck squamous cell carcinomas
    • DOI 10.1002/hed.20430
    • Stacy DR, Ely K, Massion PP, Yarbrough WG, Hallahan DE, et al. (2006) Increased expression of nuclear factor E2 p45-related factor 2 (NRF2) in head and neck squamous cell carcinomas. Head Neck 28: 813-818. (Pubitemid 44320535)
    • (2006) Head and Neck , vol.28 , Issue.9 , pp. 813-818
    • Stacy, D.R.1    Ely, K.2    Massion, P.P.3    Yarbrough, W.G.4    Hallahan, D.E.5    Sekhar, K.R.6    Freeman, M.L.7
  • 18
    • 79960060305 scopus 로고    scopus 로고
    • Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
    • DeNicola GM, Karreth FA, Humpton TJ, Gopinathan A, Wei C, et al. (2011) Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis. Nature 475: 106-109.
    • (2011) Nature , vol.475 , pp. 106-109
    • DeNicola, G.M.1    Karreth, F.A.2    Humpton, T.J.3    Gopinathan, A.4    Wei, C.5
  • 19
    • 84882452638 scopus 로고    scopus 로고
    • Oxidative stress in prostate cancer: Changing research concepts towards a novel paradigm for prevention and therapeutics
    • Paschos A, Pandya R, Duivenvoorden WC, Pinthus JH (2013) Oxidative stress in prostate cancer: changing research concepts towards a novel paradigm for prevention and therapeutics. Prostate Cancer Prostatic Dis 16: 217-225.
    • (2013) Prostate Cancer Prostatic Dis , vol.16 , pp. 217-225
    • Paschos, A.1    Pandya, R.2    Duivenvoorden, W.C.3    Pinthus, J.H.4
  • 20
    • 84878572136 scopus 로고    scopus 로고
    • Toward clinical application of the Keap1-Nrf2 pathway
    • Suzuki T, Motohashi H, Yamamoto M (2013) Toward clinical application of the Keap1-Nrf2 pathway. Trends Pharmacol Sci 34: 340-346.
    • (2013) Trends Pharmacol Sci , vol.34 , pp. 340-346
    • Suzuki, T.1    Motohashi, H.2    Yamamoto, M.3
  • 21
    • 53049105119 scopus 로고    scopus 로고
    • Genetic alteration of Keap1 confers constitutive Nrf2 activation and resistance to chemotherapy in gallbladder cancer
    • Shibata T, Kokubu A, Gotoh M, Ojima H, Ohta T, et al. (2008) Genetic alteration of Keap1 confers constitutive Nrf2 activation and resistance to chemotherapy in gallbladder cancer. Gastroenterology 135: 1358-1368, 1368 e1351-1354.
    • (2008) Gastroenterology , vol.135
    • Shibata, T.1    Kokubu, A.2    Gotoh, M.3    Ojima, H.4    Ohta, T.5
  • 22
    • 79953889329 scopus 로고    scopus 로고
    • Nrf2 is overexpressed in pancreatic cancer: Implications for cell proliferation and therapy
    • Lister A, Nedjadi T, Kitteringham NR, Campbell F, Costello E, et al. (2011) Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy. Mol Cancer 10: 37.
    • (2011) Mol Cancer , vol.10 , pp. 37
    • Lister, A.1    Nedjadi, T.2    Kitteringham, N.R.3    Campbell, F.4    Costello, E.5
  • 23
    • 84892434876 scopus 로고    scopus 로고
    • Immunohistochemical Study of the Nrf2 Pathway in Colorectal Cancer: Nrf2 Expression is Closely Correlated to Keap1 in the Tumor and Bach1 in the Normal Tissue
    • Chang LC, Fan CW, Tseng WK, Chen JR, Chein HP, et al. (2013) Immunohistochemical Study of the Nrf2 Pathway in Colorectal Cancer: Nrf2 Expression is Closely Correlated to Keap1 in the Tumor and Bach1 in the Normal Tissue. Appl Immunohistochem Mol Morphol.
    • (2013) Appl Immunohistochem Mol Morphol
    • Chang, L.C.1    Fan, C.W.2    Tseng, W.K.3    Chen, J.R.4    Chein, H.P.5
  • 25
    • 33846703755 scopus 로고    scopus 로고
    • Human prx1 gene is a target of Nrf2 and is up-regulated by hypoxia/reoxygenation: Implication to tumor biology
    • DOI 10.1158/0008-5472.CAN-06-2401
    • Kim YJ, Ahn JY, Liang P, Ip C, Zhang Y, et al. (2007) Human prx1 gene is a target of Nrf2 and is up-regulated by hypoxia/reoxygenation: implication to tumor biology. Cancer Res 67: 546-554. (Pubitemid 46192191)
    • (2007) Cancer Research , vol.67 , Issue.2 , pp. 546-554
    • Kim, Y.-J.1    Ahn, J.-Y.2    Liang, P.3    Ip, C.4    Zhang, Y.5    Park, Y.-M.6
  • 26
    • 77954695549 scopus 로고    scopus 로고
    • Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features
    • Solis LM, Behrens C, Dong W, Suraokar M, Ozburn NC, et al. (2010) Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features. Clin Cancer Res 16: 3743-3753.
    • (2010) Clin Cancer Res , vol.16 , pp. 3743-3753
    • Solis, L.M.1    Behrens, C.2    Dong, W.3    Suraokar, M.4    Ozburn, N.C.5
  • 27
    • 84862811895 scopus 로고    scopus 로고
    • Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma
    • Inoue D, Suzuki T, Mitsuishi Y, Miki Y, Suzuki S, et al. (2012) Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma. Cancer Sci 103: 760-766.
    • (2012) Cancer Sci , vol.103 , pp. 760-766
    • Inoue, D.1    Suzuki, T.2    Mitsuishi, Y.3    Miki, Y.4    Suzuki, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.