Overexpression of thioredoxin system proteins predicts poor prognosis in patients with squamous cell carcinoma of the tongue

Oral Oncology

Volumn 47, Issue 7, 2011, Pages 609-614

  Zhu, Xiaojie ^a   Huang, Congfa ^a   Peng, Bin ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

Prognosis; Tongue cancer; Trx; TrxR

Indexed keywords

THIOREDOXIN; THIOREDOXIN REDUCTASE 1;

ADULT; AGED; ARTICLE; CANCER STAGING; CARCINOGENESIS; CELL DIFFERENTIATION; CLINICAL FEATURE; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA; SURVIVAL RATE; TONGUE CARCINOMA; TONGUE SQUAMOUS CELL CARCINOMA;

ADULT; AGED; AGED, 80 AND OVER; APOPTOSIS; CARCINOMA, SQUAMOUS CELL; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NEOPLASM PROTEINS; PREDICTIVE VALUE OF TESTS; PROGNOSIS; THIOREDOXIN REDUCTASE 1; THIOREDOXINS; TONGUE NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 79959693689     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2011.05.006     Document Type: Article

References (40)

1. E.S. Arnér , and A. Holmgren The thioredoxin system in cancer Semin Cancer Biol 16 6 2006 420 426 (Pubitemid 44780139)
2. G. Powis , and D.L. Kirkpatrick Thioredoxin signaling as a target for cancer therapy Curr Opin Pharmacol 7 4 2007 392 397 (Pubitemid 47289261)
3. A.M. Kaimul , H. Nakamura , H. Masutani , and J. Yodoi Thioredoxin and thioredoxin-binding protein-2 in cancer and metabolic syndrome Free Radic Biol Med 43 6 2007 861 868 (Pubitemid 47223630)
4. K.F. Tonissen , and G. Di Trapani Thioredoxin system inhibitors as mediators of apoptosis for cancer therapy Mol Nutr Food Res 53 1 2009 87 103
5. A. Holmgren Thioredoxin Annu Rev Biochem 54 1 1985 237 271 (Pubitemid 15073647)
6. J. Yoshioka , E.R. Schreiter , and R.T. Lee Role of thioredoxin in cell growth through interactions with signaling molecules Antioxid Redox Signal 8 11-12 2006 2143 2151 (Pubitemid 46489637)
7. A. Burke-Gaffney , M.E. Callister , and H. Nakamura Thioredoxin: friend or foe in human disease? Trends Pharmacol Sci 26 8 2005 398 404 (Pubitemid 41039215)
8. T.M. Grogan , C. Fenoglio-Prieser , R. Zeheb , W. Bellamy , Y. Frutiger , and E. Vela Thioredoxin, a putative oncogene product, is overexpressed in gastric carcinoma and associated with increased proliferation and increased cell survival Hum Pathol 31 4 2000 475 481 (Pubitemid 30262870)
9. S. Kakolyris , A. Giatromanolaki , M. Koukourakis , G. Powis , J. Souglakos , and E. Sivridis Thioredoxin expression is associated with lymph node status and prognosis in early operable non-small cell lung cancer Clin Cancer Res 7 10 2001 3087 3091 (Pubitemid 32963828)
10. K. Kahlos , Y. Soini , M. Säily , P. Koistinen , S. Kakko , and P. Pääkkö Up-regulation of thioredoxin and thioredoxin reductase in human malignant pleural mesothelioma Int J Cancer 95 3 2001 198 204 (Pubitemid 32477237)
11. M.K. Cha , K.H. Suh , and I.H. Kim Overexpression of peroxiredoxin I and thioredoxin1 in human breast carcinoma J Exp Clin Cancer Res 28 1 2009 93
12. J. Raffel , A.K. Bhattacharyya , A. Gallegos , H. Cui , J.G. Einspahr , and D.S. Alberts Increased expression of thioredoxin-1 in human colorectal cancer is associated with decreased patient survival J Lab Clin Med 142 1 2003 46 51 (Pubitemid 36934520)
13. T. Noike , S. Miwa , J. Soeda , A. Kobayashi , and S. Miyagawa Increased expression of thioredoxin-1, vascular endothelial growth factor, and redox factor-1 is associated with poor prognosis in patients with liver metastasis from colorectal cancer Hum Pathol 39 2 2008 201 208
14. M. Ueno , Y. Matsutani , H. Nakamura , H. Masutani , M. Yagi , and H. Yamashiro Possible association of thioredoxin and p53 in breast cancer Immunol Lett 75 1 2000 15 20
15. S. Iwasawa , Y. Yamano , Y. Takiguchi , H. Tanzawa , K. Tatsumi , and K. Uzawa Upregulation of thioredoxin reductase 1 in human oral squamous cell carcinoma Oncol Rep 25 3 2011 637 644
16. Y. Okada Relationships of cervical lymph node metastasis to histopathological malignancy grade, tumor angiogenesis, and lymphatic invasion in tongue cancer Odontology 98 2 2010 153 159
17. I.J. Hoogsteen , H.A. Marres , J. Bussink , A.J. Van der Kogel , and J.H. Kaanders Tumor microenvironment in head and neck squamous cell carcinomas: predictive value and clinical relevance of hypoxic markers. A review Head Neck 29 6 2007 591 604 (Pubitemid 47324777)
18. C.D. Ko , J.S. Kim , B.G. Ko , B.H. Son , H.J. Kang , and H.S. Yoon The meaning of the c-kit proto-oncogene product in malignant transformation in human mammary epithelium Clin Exp Metastasis 20 7 2003 593 597 (Pubitemid 37463896)
19. D.T. Lincoln , F. Al-Yatama , F.M. Mohammed , A.G. Al-Banaw , M. Al-Bader , and M. Burge Thioredoxin and thioredoxin reductase expression in thyroid cancer depends on tumour aggressiveness Anticancer Res 30 3 2010 767 775
20. H.J. Kim , H.Z. Chae , Y.J. Kim , Y.H. Kim , T.S. Hwangs , and E.M. Park Preferential elevation of Prx I and Trx expression in lung cancer cells following hypoxia and in human lung cancer tissues Cell Biol Toxicol 19 5 2003 285 298 (Pubitemid 38002149)
21. Y. Soini , K. Kahlos , U. Näpänkangas , R. Kaarteenaho-Wiik , M. Säily , and P. Koistinen Widespread expression of thioredoxin and thioredoxin reductase in nonsmall cell lung carcinoma Clin Cancer Res 7 6 2001 1750 1757 (Pubitemid 32708645)
22. M.D. Evans , M. Dizdaroglu , and M.S. Cooke Oxidative DNA damage and disease: induction, repair and significance Mutat Res 567 1 2004 1 61 (Pubitemid 39162992)
23. G. Fujino , T. Noguchi , K. Takeda , and H. Ichijo Thioredoxin and protein kinases in redox signaling Semin Cancer Biol 16 6 2006 427 435 (Pubitemid 44794596)
24. M. Saitoh , H. Nishitoh , M. Fujii , K. Takeda , K. Tobiume , and Y. Sawada Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1 EMBO J 17 1998 2596 2606 (Pubitemid 28221195)
25. K. Hattori , I. Naguro , C. Runchel , and H. Ichijo The roles of ASK family proteins in stress responses and diseases Cell Commun Signal 7 2009 9
26. H. Liu , H. Nishitoh , H. Ichijo , and J.M. Kyriakis Activation of apoptosis signal-regulating kinase 1 (ASK1) by tumor necrosis factor receptor-associated factor 2 requires prior dissociation of the ASK1 inhibitor thioredoxin Mol Cell Biol 20 2000 2198 2208 (Pubitemid 30123835)
27. E.S. Arnér , and A. Holmgren Physiological functions of thioredoxin and thioredoxin reductase Eur J Biochem 267 20 2000 6102 6109
28. D.T. Lincoln , E.M. Ali Emadi , K.F. Tonissen , and F.M. Clarke The thioredoxin-thioredoxin reductase system: over-expression in human cancer Anticancer Res 23 3B 2003 2425 2433 (Pubitemid 36897112)
29. D. Hanahan , and R.A. Weinberg The hallmarks of cancer Cell 100 1 2000 57 70 (Pubitemid 30046295)
30. W.J. Kim , H. Cho , S.W. Lee , Y.J. Kim , and K.W. Kim Antisense-thioredoxin inhibits angiogenesis via pVHL-mediated hypoxia-inducible factor-1 alpha degradation Int J Oncol 26 4 2005 1049 1052
31. S.J. Welsh , W.T. Bellamy , M.M. Briehl , and G. Powis The redox protein thioredoxin-1 (Trx-1) increases hypoxia-inducible factor 1alpha protein expression: Trx-1 overexpression results in increased vascular endothelial growth factor production and enhanced tumor angiogenesis Cancer Res 62 17 2002 5089 5095 (Pubitemid 34984438)
32. H. Nakamura , H. Masutani , Y. Tagaya , A. Yamauchi , T. Inamoto , and Y. Nanbu Expression and growth-promoting effect of adult T-cell leukemia-derived factor. A human thioredoxin homologue in hepatocellular carcinoma Cancer 69 8 1992 2091 2097
33. N. Wakasugi , Y. Tagaya , H. Wakasugi , A. Mitsui , M. Maeda , and J. Yodoi Adult T-cell leukemia-derived factor/thioredoxin, produced by both human T-lymphotropic virus type I- and Epstein-Barr virus-transformed lymphocytes, acts as an autocrine growth factor and synergizes with interleukin 1 and interleukin 2 Proc Natl Acad Sci U S A 87 21 1990 8282 8286
34. A.R. Farina , A. Tacconelli , L. Cappabianca , M.P. Masciulli , A. Holmgren , and G.J. Beckett Thioredoxin alters the matrix metalloproteinase/ tissue inhibitors of metalloproteinase balance and stimulates human SK-N-SH neuroblastoma cell invasion Eur J Biochem 268 2 2001 405 413 (Pubitemid 32862672)
35. L. Gan , X.L. Yang , Q. Liu , and H.B. Xu Inhibitory effects of thioredoxin reductase antisense RNA on the growth of human hepatocellular carcinoma cells J Cell Biochem 96 2005 653 664 (Pubitemid 41504662)
36. L.M. Butler , X. Zhou , W.S. Xu , H.I. Scher , R.A. Rifkind , and P.A. Marks The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin Proc Natl Acad Sci USA 99 18 2002 11700 11705 (Pubitemid 34994462)
37. A. Casini , C. Hartinger , C. Gabbiani , E. Mini , P.J. Dyson , and B.K. Keppler Gold(III) compounds as anticancer agents: relevance of gold-protein interactions for their mechanism of action J Inorg Biochem 102 3 2008 564 575
38. J. Lu , E.H. Chew , and A. Holmgren Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide Proc Natl Acad Sci USA 104 30 2007 12288 12293 (Pubitemid 47206130)
39. D. Magda , and R.A. Miller Motexafin gadolinium: a novel redox active drug for cancer therapy Semin Cancer Biol 16 6 2006 466 476 (Pubitemid 44780135)
40. J. Lu , L.V. Papp , J. Fang , S. Rodriguez-Nieto , B. Zhivotovsky , and A. Holmgren Inhibition of mammalian thioredoxin reductase by some flavonoids: implications for myricetin and quercetin anticancer activity Cancer Res 66 8 2006 4410 4418