Polymorphism of rs1836882 in NOX4 gene modifies associations between dietary caloric intake and ROS levels in peripheral blood mononuclear cells

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Liu, Qiang ^a   Li, Hong ^b   Wang, Ningfu ^b   Chen, Huaihong ^a   Jin, Qihui ^a   Zhang, Ruoyu ^a   Wang, Jing ^a   Chen, Ying ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; DIET; DOWN-REGULATION; ENERGY INTAKE; FEMALE; HEPATOCYTE NUCLEAR FACTOR 3-GAMMA; HUMANS; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; NADPH OXIDASE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; REACTIVE OXYGEN SPECIES; TRANSCRIPTION, GENETIC;

EID: 84893531592     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0085660     Document Type: Article

References (46)

1. Aballay LR, Eynard AR, Diaz Mdel P, Navarro A, Muñoz SE (2013) Overweight and obesity: a review of their relationship to metabolic syndrome, cardiovascular disease, and cancer in South America. Nutr Rev 71: 168-179. doi:10.1111/j.1753-4887.2012.00533.x. PubMed: 23452284.
2. Landsberg L, Aronne LJ, Beilin LJ, Burke V, Igel LI et al. (2013) Obesity-related hypertension: pathogenesis, cardiovascular risk, and treatment: a position paper of The Obesity Society and the American Society of Hypertension. J Clin Hypertens (Greenwich) 15: 14-33. doi: 10.1111/jch.12049. PubMed: 23282121.
3. Hursting SD, Digiovanni J, Dannenberg AJ, Azrad M, Leroith D et al. (2012) Obesity, energy balance, and cancer: new opportunities for prevention. Cancer. Prev Res (Phila) 5: 1260-1272. doi: 10.1158/1940-6207.CAPR-12-0140.
4. Rothman SM, Griffioen KJ, Wan R, Mattson MP (2012) Brain-derived neurotrophic factor as a regulator of systemic and brain energy metabolism and cardiovascular health. Ann N Y Acad Sci 1264: 49-63. doi:10.1111/j.1749-6632. 2012.06525.x. PubMed: 22548651.
5. Omodei D, Fontana L (2011) Calorie restriction and prevention of age-associated chronic disease. FEBS Lett 585: 1537-1542. doi:10.1016/j.febslet. 2011.03.015. PubMed: 21402069.
6. Speakman JR, Mitchell SE (2011) Caloric restriction. Mol Aspects Med 32: 159-221. doi:10.1016/j.mam.2011.07.001. PubMed: 21840335.
7. Ivanova DG, Yankova TM (2013) The free radical theory of aging in search of a strategy for increasing life span. Folia Med (Plovdiv) 55: 33-41. PubMed: 23905485.
8. Sohal RS, Weindruch R (1996) Oxidative stress, caloric restriction, and aging. Science (New York, NY) 273: 59-63. doi:10.1126/science. 273.5271.59.
9. Gredilla R, Barja G (2005) Minireview: the role of oxidative stress in relation to caloric restriction and longevity. Endocrinology 146: 3713-3717. doi:10.1210/en.2005-0378. PubMed: 15919745. (Pubitemid 41175737)
10. Barja G (2013) Updating the mitochondrial free radical theory of aging: an integrated view, key aspects, and confounding concepts. Antioxid Redox Signal 19: 1420-1445. doi:10.1089/ars.2012.5148. PubMed: 23642158.
11. Barja G (2004) Free radicals and aging. Trends Neurosci 27: 595-600. doi:10.1016/j.tins.2004.07.005. PubMed: 15374670.
12. El Assar M, Angulo J, Rodriguez-Manas L (2013) Oxidative stress and vascular inflammation in aging. Free Radic Biol Med 65C: 380-401.
13. Donato AJ, Walker AE, Magerko KA, Bramwell RC, Black AD et al. (2013) Life-long caloric restriction reduces oxidative stress and preserves nitric oxide bioavailability and function in arteries of old mice. Aging Cell 12: 772-783. doi:10.1111/acel.12103. PubMed: 23714110.
14. Rippe C, Lesniewski L, Connell M, LaRocca T, Donato A et al. (2010) Short-term calorie restriction reverses vascular endothelial dysfunction in old mice by increasing nitric oxide and reducing oxidative stress. Aging Cell 9: 304-312. doi:10.1111/j.1474-9726.2010.00557.x. PubMed: 20121721.
15. Zanetti M, Gortan Cappellari G, Burekovic I, Barazzoni R, Stebel M et al. (2010) Caloric restriction improves endothelial dysfunction during vascular aging: Effects on nitric oxide synthase isoforms and oxidative stress in rat aorta. Exp Gerontol 45: 848-855. doi:10.1016/j.exger.2010.07.002. PubMed: 20637278.
16. Ketonen J, Pilvi T, Mervaala E (2010) Caloric restriction reverses high-fat diet-induced endothelial dysfunction and vascular superoxide production in C57Bl/6 mice. Heart Vessels 25: 254-262. doi:10.1007/s00380-009-1182-x. PubMed: 20512454.
17. Altenhöfer S, Kleikers PW, Radermacher KA, Scheurer P, Rob Hermans JJ et al. (2012) The NOX toolbox: validating the role of NADPH oxidases in physiology and disease. Cell Mol Life Sci 69: 2327-2343. doi:10.1007/s00018-012- 1010-9. PubMed: 22648375.
18. Kofler PA, Pircher H, von Grafenstein S, Diener T, Höll M et al. (2013) Characterisation of Nox4 inhibitors from edible plants. Planta Med 79: 244-252. doi:10.1055/s-0032-1328129. PubMed: 23345167.
19. Li JZ, Yu SY, Wu JH, Shao QR, Dong XM (2012) Paeoniflorin protects myocardial cell from doxorubicin-induced apoptosis through inhibition of NADPH oxidase. Can J Physiol Pharmacol 90: 1569-1575. doi: 10.1139/y2012-140. PubMed: 23210435.
20. Stasi MA, Scioli MG, Arcuri G, Mattera GG, Lombardo K et al. (2010) Propionyl-L-carnitine improves postischemic blood flow recovery and arteriogenetic revascularization and reduces endothelial NADPH-oxidase 4-mediated superoxide production. Arterioscler Thromb Vasc Biol 30: 426-435. doi:10.1161/ATVBAHA.109.201533. PubMed: 20056909.
21. Wilkinson-Berka JL, Rana I, Armani R, Agrotis A (2013) Reactive oxygen species, Nox and angiotensin II in angiogenesis: implications for retinopathy. Clin Sci (Lond) 124: 597-615
22. Chen F, Haigh S, Barman S, Fulton DJ (2012) From form to function: the role of Nox4 in the cardiovascular system. Front - Physiol (Bethesda, Md.) 3: 412. PubMed: 23125837.
23. Nabeebaccus A, Zhang M, Shah AM (2011) NADPH oxidases and cardiac remodelling. Heart Fail Rev 16: 5-12. doi:10.1007/s10741-010-9186-2. PubMed: 20658317.
24. Fitzgerald JP, Nayak B, Shanmugasundaram K, Friedrichs W, Sudarshan S et al. (2012) Nox4 mediates renal cell carcinoma cell invasion through hypoxia-induced interleukin 6- and 8- production. PLOS ONE 7: e30712. doi:10.1371/journal.pone.0030712. PubMed: 22303451.
25. Zhang M, Perino A, Ghigo A, Hirsch E, Shah AM (2013) NADPH oxidases in heart failure: poachers or gamekeepers? Antioxid Redox Signal 18: 1024-1041. doi:10.1089/ars.2012.4550. PubMed: 22747566.
26. Kleinschnitz C, Grund H, Wingler K, Armitage ME, Jones E et al. (2010) Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration. PLoS Biol 8: ([MedlinePgn:]) PubMed: 20877715.
27. Panowski SH, Wolff S, Aguilaniu H, Durieux J, Dillin A (2007) PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans. Nature 447: 550-555. doi:10.1038/nature05837. PubMed: 17476212. (Pubitemid 46868041)
28. Liu Q, Li H, Chen HH, Wang J (2012) Caloric restriction suppresses endothelial cells senescence via down-regulation of NOX4 induced by HNF3gamma. Yi Chuan 34: 573-583. doi:10.3724/SP.J. 1005.2012.00573. PubMed: 22659429.
29. Crujeiras AB, Parra D, Milagro FI, Goyenechea E, Larrarte E et al. (2008) Differential expression of oxidative stress and inflammation related genes in peripheral blood mononuclear cells in response to a low-calorie diet: a nutrigenomics study. Omics 12: 251-261. doi: 10.1089/omi.2008.0001. PubMed: 18687040. (Pubitemid 352773935)
30. Zhang M, Huang B (2012) The multi-differentiation potential of peripheral blood mononuclear cells. Stem Cell Res Ther 3: 48. doi: 10.1186/scrt139. PubMed: 23200034.
31. Ngkelo A, Meja K, Yeadon M, Adcock I, Kirkham PA (2012) LPS induced inflammatory responses in human peripheral blood mononuclear cells is mediated through NOX4 and Gialpha dependent PI-3kinase signalling. J Inflamm (Lond) 9: 1. doi: 10.1186/1476-9255-9-1.
32. Moreno MU, San Jose G, Fortuno A, Miguel-Carrasco JL, Beloqui O, et al. (2011) The A640G CYBA polymorphism associates with subclinical atherosclerosis in diabetes. Front Biosci (Elite Ed) 3: 1467-1474
33. Cariello M, Simone S, Loverre A, Gigante M, Incampo F et al. (2012) Coagulation activation is associated with nicotinamide adenine dinucleotide phosphate oxidase-dependent reactive oxygen species generation in hemodialysis patients. Antioxid Redox Signal 16: 428-439. doi:10.1089/ars.2011.4062. PubMed: 22191478.
34. Jenkins NT, Landers RQ, Prior SJ, Soni N, Spangenburg EE, et al. (2011) Effects of acute and chronic endurance exercise on intracellular nitric oxide and superoxide in circulating CD34(+) and CD34(-) cells. J Appl Physiol (1985) 111: 929-937
35. Cal LA, Maso LD, Caielli P, Pagnin E, Fusaro M et al. (2011) Effect of olmesartan on oxidative stress in hypertensive patients: mechanistic support to clinical trials derived evidence. Blood Press 20: 376-382. doi: 10.3109/08037051.2011.575570. PubMed: 21504378.
36. Matsuo T, Nakata Y, Murotake Y, Hotta K, Tanaka K (2012) Effects of FTO genotype on weight loss and metabolic risk factors in response to calorie restriction among Japanese women. Obesity (Silver Spring) 20: 1122-1126. doi:10.1038/oby.2011.322. PubMed: 22016090.
37. Sevastianova K, Kotronen A, Gastaldelli A, Perttilä J, Hakkarainen A et al. (2011) Genetic variation in PNPLA3 (adiponutrin) confers sensitivity to weight loss-induced decrease in liver fat in humans. Am J Clin Nutr 94: 104-111. doi:10.3945/ajcn.111.012369. PubMed: 21525193.
38. Vaccaro O, Lapice E, Monticelli A, Giacchetti M, Castaldo I et al. (2007) Pro12Ala polymorphism of the PPARgamma2 locus modulates the relationship between energy intake and body weight in type 2 diabetic patients. Diabetes Care 30: 1156-1161. doi:10.2337/dc06-1153. PubMed: 17259473. (Pubitemid 46684641)
39. Lee MS, Pan WH, Liu KL, Yu MS (2006) Reproducibility and validity of a Chinese food frequency questionnaire used in Taiwan. Asia Pac J Clin Nutr 15: 161-169. PubMed: 16672199.
40. Pisciotta A, Riccio M, Carnevale G, Beretti F, Gibellini L et al. (2012) Human serum promotes osteogenic differentiation of human dental pulp stem cells in vitro and in vivo. PLOS ONE 7: e50542. doi:10.1371/journal.pone.0050542. PubMed: 23209773.
41. Shi YY, He L (2005) SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci. Cell Res 15: 97-98. doi:10.1038/sj.cr.7290272. PubMed: 15740637. (Pubitemid 41653949)
42. Banasik K, Hollensted M, Andersson E, Sparsø T, Sandbaek A et al. (2012) The effect of FOXA2 rs1209523 on glucose-related phenotypes and risk of type 2 diabetes in Danish individuals. BMC Med Genet 13: 10. doi:10.1186/1471-2350-13-10. PubMed: 22325233.
43. Guo J, Ren W, Ding Y, Li A, Jia L et al. (2012) Fat mass and obesity associated gene (FTO) expression is regulated negatively by the transcription factor Foxa2. PLOS ONE 7: e51082. doi:10.1371/journal.pone.0051082. PubMed: 23236435.
44. Li Z, Tuteja G, Schug J, Kaestner KH (2012) Foxa1 and Foxa2 are essential for sexual dimorphism in liver cancer. Cell 148: 72-83. doi: 10.1016/j.cell.2011.11.026. PubMed: 22265403.
45. Varga ZV, Kupai K, Szu{combining double acute accent}cs G, Gáspár R, Pálóczi J et al. (2013) MicroRNA-25-dependent up-regulation of NADPH oxidase 4 (NOX4) mediates hypercholesterolemia-induced oxidative/nitrative stress and subsequent dysfunction in the heart. J Mol Cell Cardiol, 62: 111-21. PubMed: 23722270.
46. Fenyo IM, Florea IC, Raicu M, Manea A (2011) Tyrphostin AG490 reduces NAPDH oxidase activity and expression in the aorta of hypercholesterolemic apolipoprotein E-deficient mice. Vascul Pharmacol 54: 100-106. doi:10.1016/j.vph.2011.03.006. PubMed: 21457788.