Serines 440 and 467 in the Werner syndrome protein are phosphorylated by DNA-PK and affects its dynamics in response to DNA double strand breaks

Aging

Volumn 6, Issue 1, 2014, Pages 70-81

  Kusumoto Matsuo, Rika ^a   Ghosh, Deblina ^b   Karmakar, Parimal ^b   May, Alfred ^a   Ramsden, Dale ^c   Bohr, Vilhelm A ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b JADAVPUR UNIVERSITY   (India)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

DNA PK; DSB; Etoposide; Serine phosphorylation; Werner; WRN

Indexed keywords

BLEOMYCIN; DNA DEPENDENT PROTEIN KINASE; ETOPOSIDE; EXODEOXYRIBONUCLEASE; NUCLEAR PROTEIN; PRKDC PROTEIN, HUMAN; RECQ HELICASE; SERINE; WRN PROTEIN, HUMAN;

ARTICLE; DNA REPAIR; DOSE RESPONSE; DOUBLE STRANDED DNA BREAK; DRUG EFFECT; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; HEK293 CELL LINE; HELA CELL LINE; HUMAN; KINETICS; METABOLISM; MUTATION; NUCLEOLUS; PHOSPHORYLATION; PROTEIN PROCESSING;

BLEOMYCIN; CELL NUCLEOLUS; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA-ACTIVATED PROTEIN KINASE; DOSE-RESPONSE RELATIONSHIP, DRUG; ETOPOSIDE; EXODEOXYRIBONUCLEASES; HEK293 CELLS; HELA CELLS; HUMANS; KINETICS; MUTATION; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECQ HELICASES; SERINE; TRANSFECTION;

EID: 84893519107     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100629     Document Type: Article

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