메뉴 건너뛰기




Volumn 289, Issue 5, 2014, Pages 2497-2514

Genetic signatures of HIV-1 envelope-mediated bystander apoptosis

Author keywords

[No Author keywords available]

Indexed keywords

AIDS; APOPTOSIS; GENETICS; HIV; INFECTIOUS DISEASES; RETROVIRUS; VIROLOGY;

EID: 84893510188     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.514018     Document Type: Article
Times cited : (15)

References (91)
  • 2
    • 84870626171 scopus 로고    scopus 로고
    • HIV-1 induced bystander apoptosis
    • Garg, H., Mohl, J., and Joshi, A. (2012) HIV-1 induced bystander apoptosis. Viruses 4, 3020-3043
    • (2012) Viruses , vol.4 , pp. 3020-3043
    • Garg, H.1    Mohl, J.2    Joshi, A.3
  • 3
    • 35748939690 scopus 로고    scopus 로고
    • HIV disease progression. Immune activation, microbes, and a leaky gut
    • Douek, D. (2007) HIV disease progression. Immune activation, microbes, and a leaky gut. Top. HIV Med. 15, 114-117
    • (2007) Top. HIV Med. , vol.15 , pp. 114-117
    • Douek, D.1
  • 5
    • 79961179950 scopus 로고    scopus 로고
    • Evolution of human immunodeficiency virus type 1 in a patient with cross-reactive neutralizing activity in serum
    • Van Gils, M. J., Edo-Matas, D., Bowles, E. J., Burger, J. A., Stewart-Jones, G. B., and Schuitemaker, H. (2011) Evolution of human immunodeficiency virus type 1 in a patient with cross-reactive neutralizing activity in serum. J. Virol. 85, 8443-8448
    • (2011) J. Virol. , vol.85 , pp. 8443-8448
    • Van Gils, M.J.1    Edo-Matas, D.2    Bowles, E.J.3    Burger, J.A.4    Stewart-Jones, G.B.5    Schuitemaker, H.6
  • 6
    • 0027297036 scopus 로고
    • Apoptosis in AIDS
    • Gougeon, M. L., and Montagnier, L. (1993) Apoptosis in AIDS. Science 260, 1269-1270
    • (1993) Science , vol.260 , pp. 1269-1270
    • Gougeon, M.L.1    Montagnier, L.2
  • 7
    • 0029061073 scopus 로고
    • Mechanism of apoptosis in peripheral blood mononuclear cells of HIV-infected patients
    • Oyaizu, N., McCloskey, T. W., Than, S., Hu, R., and Pahwa, S. (1995) Mechanism of apoptosis in peripheral blood mononuclear cells of HIV-infected patients. Adv. Exp. Med. Biol. 374, 101-114
    • (1995) Adv. Exp. Med. Biol. , vol.374 , pp. 101-114
    • Oyaizu, N.1    McCloskey, T.W.2    Than, S.3    Hu, R.4    Pahwa, S.5
  • 8
    • 0027497028 scopus 로고
    • Accelerated apoptosis in peripheral blood mononuclear cells (PBMCs) from human immunodeficiency virus type-1 infected patients and in CD4 cross-linked PBMCs from normal individuals
    • Oyaizu, N., McCloskey, T. W., Coronesi, M., Chirmule, N., Kalyanaraman, V. S., and Pahwa, S. (1993) Accelerated apoptosis in peripheral blood mononuclear cells (PBMCs) from human immunodeficiency virus type-1 infected patients and in CD4 cross-linked PBMCs from normal individuals. Blood 82, 3392-3400
    • (1993) Blood , vol.82 , pp. 3392-3400
    • Oyaizu, N.1    McCloskey, T.W.2    Coronesi, M.3    Chirmule, N.4    Kalyanaraman, V.S.5    Pahwa, S.6
  • 9
    • 0028912254 scopus 로고
    • Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes
    • Finkel, T. H, Tudor-Williams, G., Banda, N. K., Cotton, M. F., Curiel, T., Monks, C, Baba, T. W., Ruprecht, R. M., and Kupfer, A. (1995) Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes. Nat. Med. 1, 129-134
    • (1995) Nat. Med. , vol.1 , pp. 129-134
    • Finkel, T.H.1    Tudor-Williams, G.2    Banda, N.K.3    Cotton, M.F.4    Curiel, T.5    Monks, C.6    Baba, T.W.7    Ruprecht, R.M.8    Kupfer, A.9
  • 10
    • 59149106173 scopus 로고    scopus 로고
    • Kinetics of T lymphocyte apoptosis and the cellular immune response in SIVmac239-infected rhesus macaques
    • Meythaler, M., Pryputniewicz, S., and Kaur, A. (2008) Kinetics of T lymphocyte apoptosis and the cellular immune response in SIVmac239-infected rhesus macaques. J. Med. Primatol. 37, 33-45
    • (2008) J. Med. Primatol. , vol.37 , pp. 33-45
    • Meythaler, M.1    Pryputniewicz, S.2    Kaur, A.3
  • 11
    • 78651573484 scopus 로고    scopus 로고
    • Single amino acid change in gp41 region of HIV-1 alters bystander apoptosis and CD4 decline in humanized mice
    • Garg, H, Joshi, A., Ye, C, Shankar, P., and Manjunath, N. (2011) Single amino acid change in gp41 region of HIV-1 alters bystander apoptosis and CD4 decline in humanized mice. Virol. J. 8, 34
    • (2011) Virol. J. , vol.8 , pp. 34
    • Garg, H.1    Joshi, A.2    Ye, C.3    Shankar, P.4    Manjunath, N.5
  • 15
    • 82355180939 scopus 로고    scopus 로고
    • The evolution of human immunodeficiency virus type-1 (HIV-1) envelope molecular properties and coreceptor use at all stages of infection in an HIV-1 donorrecipient pair
    • Edo-Matas, D., Rachinger, A., Setiawan, L. C, Boeser-Nunnink, B. D., Van't Wout, A. B., Lemey, P., and Schuitemaker, H. (2012) The evolution of human immunodeficiency virus type-1 (HIV-1) envelope molecular properties and coreceptor use at all stages of infection in an HIV-1 donorrecipient pair. Virology 422, 70-80
    • (2012) Virology , vol.422 , pp. 70-80
    • Edo-Matas, D.1    Rachinger, A.2    Setiawan, L.C.3    Boeser-Nunnink, B.D.4    Van't Wout, A.B.5    Lemey, P.6    Schuitemaker, H.7
  • 16
    • 49149100897 scopus 로고    scopus 로고
    • Molecular evolution of human immunodeficiency virus type 1 upon transmission between human leukocyte antigen disparate donor-recipient pairs
    • Navis, M., Matas, D. E., Rachinger, A., Koning, F. A., Van Swieten, P., Kootstra, N. A., and Schuitemaker, H. (2008) Molecular evolution of human immunodeficiency virus type 1 upon transmission between human leukocyte antigen disparate donor-recipient pairs. PLoS One 3, e2422
    • (2008) PLoS One , vol.3
    • Navis, M.1    Matas, D.E.2    Rachinger, A.3    Koning, F.A.4    Van Swieten, P.5    Kootstra, N.A.6    Schuitemaker, H.7
  • 17
    • 0037551476 scopus 로고
    • Genomic diversity of the acquired immune deficiency syndrome virus HTLV-III. Different viruses exhibit greatest divergence in their envelope genes
    • Hahn, B. H., Gonda, M. A., Shaw, G. M., Popovic, M., Hoxie, J. A., Gallo, R. C, and Wong-Staal, F. (1985) Genomic diversity of the acquired immune deficiency syndrome virus HTLV-III. Different viruses exhibit greatest divergence in their envelope genes. Proc. Natl. Acad. Sci. U. S. A. 82, 4813-4817
    • (1985) Proc. Natl. Acad. Sci. U. S. A. , vol.82 , pp. 4813-4817
    • Hahn, B.H.1    Gonda, M.A.2    Shaw, G.M.3    Popovic, M.4    Hoxie, J.A.5    Gallo, R.C.6    Wong-Staal, F.7
  • 19
    • 0032519395 scopus 로고    scopus 로고
    • Evolution of human immunodeficiency virus type 1 envelope sequences in infected individuals with differing disease progression profiles
    • Shankarappa, R., Gupta, P., Learn, G. H., Jr., Rodrigo, A. G., Rinaldo, C. R., Jr., Gorry, M. C, Mullins, J. I., Nara, P. L., and Ehrlich, G. D. (1998) Evolution of human immunodeficiency virus type 1 envelope sequences in infected individuals with differing disease progression profiles. Virology 241, 251-259
    • (1998) Virology , vol.241 , pp. 251-259
    • Shankarappa, R.1    Gupta, P.2    Learn Jr., G.H.3    Rodrigo, A.G.4    Rinaldo Jr., C.R.5    Gorry, M.C.6    Mullins, J.I.7    Nara, P.L.8    Ehrlich, G.D.9
  • 22
    • 79952619253 scopus 로고    scopus 로고
    • Comparison of in vivo and in vitro evolution of CCR5 to CXCR4 coreceptor use of primary human immunodeficiency virus type 1 variants
    • Edo-Matas, D., Van Dort, K. A., Setiawan, L. C, Schuitemaker, H., and Kootstra, N. A. (2011) Comparison of in vivo and in vitro evolution of CCR5 to CXCR4 coreceptor use of primary human immunodeficiency virus type 1 variants. Virology 412, 269-277
    • (2011) Virology , vol.412 , pp. 269-277
    • Edo-Matas, D.1    Van Dort, K.A.2    Setiawan, L.C.3    Schuitemaker, H.4    Kootstra, N.A.5
  • 23
    • 0026600926 scopus 로고
    • Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection. Progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population
    • Schuitemaker, H, Koot, M., Kootstra, N. A., Dercksen, M. W., De Goede, R. E., Van Steenwijk, R. P., Lange, J. M., Schattenkerk, J. K., Miedema, F., and Tersmette, M. (1992) Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection. Progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population. J. Virol. 66, 1354-1360
    • (1992) J. Virol. , vol.66 , pp. 1354-1360
    • Schuitemaker, H.1    Koot, M.2    Kootstra, N.A.3    Dercksen, M.W.4    De Goede, R.E.5    Van Steenwijk, R.P.6    Lange, J.M.7    Schattenkerk, J.K.8    Miedema, F.9    Tersmette, M.10
  • 28
    • 2442765375 scopus 로고    scopus 로고
    • Phenotypic characteristics of human immunodeficiency virus type 1 subtype C isolates of Ethiopian AIDS patients
    • Bjorndal, A., Sonnerborg, A., Tscherning, C, Albert, J., and Fenyo, E. M. (1999) Phenotypic characteristics of human immunodeficiency virus type 1 subtype C isolates of Ethiopian AIDS patients. AIDS Res. Hum. Retroviruses 15, 647-653
    • (1999) AIDS Res. Hum. Retroviruses , vol.15 , pp. 647-653
    • Bjorndal, A.1    Sonnerborg, A.2    Tscherning, C.3    Albert, J.4    Fenyo, E.M.5
  • 29
    • 84862744172 scopus 로고    scopus 로고
    • CD8+ T cells in preventing HIV infection and disease
    • McDermott, A. B., and Koup, R. A. (2012) CD8+ T cells in preventing HIV infection and disease. AIDS 26, 1281-1292
    • (2012) AIDS , vol.26 , pp. 1281-1292
    • McDermott, A.B.1    Koup, R.A.2
  • 30
    • 77957584418 scopus 로고    scopus 로고
    • T cell immunity in acute HIV-1 infection
    • Streeck, H., and Nixon, D. F. (2010) T cell immunity in acute HIV-1 infection. J. Infect. Dis. 202, S302-S308
    • (2010) J. Infect. Dis. , vol.202
    • Streeck, H.1    Nixon, D.F.2
  • 31
    • 22144473726 scopus 로고    scopus 로고
    • HIV-1 envelope evolution and vaccine efficacy
    • Mosier, D. E. (2005) HIV-1 envelope evolution and vaccine efficacy. Curr. Drug Targets Infect. Disord. 5, 171-177
    • (2005) Curr. Drug Targets Infect. Disord. , vol.5 , pp. 171-177
    • Mosier, D.E.1
  • 33
    • 33748925430 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 V1-V2 envelope loop sequences expand and add glycosylation sites over the course of infection, and these modifications affect antibody neutralization sensitivity
    • Sagar, M., Wu, X., Lee, S., and Overbaugh, J. (2006) Human immunodeficiency virus type 1 V1-V2 envelope loop sequences expand and add glycosylation sites over the course of infection, and these modifications affect antibody neutralization sensitivity. J. Virol. 80, 9586-9598
    • (2006) J. Virol. , vol.80 , pp. 9586-9598
    • Sagar, M.1    Wu, X.2    Lee, S.3    Overbaugh, J.4
  • 34
    • 79960405099 scopus 로고    scopus 로고
    • Longer V1V2 region with increased number of potential N-linked glycosylation sites in the HIV-1 envelope glycoprotein protects against HIV-specific neutralizing antibodies
    • Van Gils, M. J., Bunnik, E. M., Boeser-Nunnink, B. D., Burger, J. A., Terlouw-Klein, M., Verwer, N., and Schuitemaker, H. (2011) Longer V1V2 region with increased number of potential N-linked glycosylation sites in the HIV-1 envelope glycoprotein protects against HIV-specific neutralizing antibodies. J. Virol. 85, 6986-6995
    • (2011) J. Virol. , vol.85 , pp. 6986-6995
    • Van Gils, M.J.1    Bunnik, E.M.2    Boeser-Nunnink, B.D.3    Burger, J.A.4    Terlouw-Klein, M.5    Verwer, N.6    Schuitemaker, H.7
  • 36
    • 0032731642 scopus 로고    scopus 로고
    • Persistent CCR5 utilization and enhanced macrophage tropism by primary blood human immunodeficiency virus type 1 isolates from advanced stages of disease and comparison to tissue-derived isolates
    • Li, S., Juarez, J., Alali, M., Dwyer, D., Collman, R., Cunningham, A., and Naif, H. M. (1999) Persistent CCR5 utilization and enhanced macrophage tropism by primary blood human immunodeficiency virus type 1 isolates from advanced stages of disease and comparison to tissue-derived isolates. J. Virol. 73, 9741-9755
    • (1999) J. Virol. , vol.73 , pp. 9741-9755
    • Li, S.1    Juarez, J.2    Alali, M.3    Dwyer, D.4    Collman, R.5    Cunningham, A.6    Naif, H.M.7
  • 37
    • 20444395434 scopus 로고    scopus 로고
    • Uncoupling coreceptor usage of human immunodeficiency virus type 1 (HIV-1) from macrophage tropism reveals biological properties of CCR5-restricted HIV-1 isolates from patients with acquired immunodeficiency syndrome
    • Gray, L., Sterjovski, J., Churchill, M., Ellery, P., Nasr, N., Lewin, S. R., Crowe, S. M., Wesselingh, S. L., Cunningham, A. L., and Gorry, P. R. (2005) Uncoupling coreceptor usage of human immunodeficiency virus type 1 (HIV-1) from macrophage tropism reveals biological properties of CCR5-restricted HIV-1 isolates from patients with acquired immunodeficiency syndrome. Virology 337, 384-398
    • (2005) Virology , vol.337 , pp. 384-398
    • Gray, L.1    Sterjovski, J.2    Churchill, M.3    Ellery, P.4    Nasr, N.5    Lewin, S.R.6    Crowe, S.M.7    Wesselingh, S.L.8    Cunningham, A.L.9    Gorry, P.R.10
  • 38
    • 33847281316 scopus 로고    scopus 로고
    • Macrophage entry mediated by HIV Envs from brain and lymphoid tissues is determined by the capacity to use low CD4 levels and overall efficiency of fusion
    • Thomas, E. R., Dunfee, R. L., Stanton, J., Bogdan, D., Taylor, J., Kunstman, K., Bell, J. E., Wolinsky, S. M., and Gabuzda, D. (2007) Macrophage entry mediated by HIV Envs from brain and lymphoid tissues is determined by the capacity to use low CD4 levels and overall efficiency of fusion. Virology 360, 105-119
    • (2007) Virology , vol.360 , pp. 105-119
    • Thomas, E.R.1    Dunfee, R.L.2    Stanton, J.3    Bogdan, D.4    Taylor, J.5    Kunstman, K.6    Bell, J.E.7    Wolinsky, S.M.8    Gabuzda, D.9
  • 40
    • 34447121955 scopus 로고    scopus 로고
    • Site-specific mutations in HIV-1 gp41 reveal a correlation between HIV-1-mediated bystander apoptosis and fusion/hemifusion
    • Garg, H., Joshi, A., Freed, E. O., and Blumenthal, R. (2007) Site-specific mutations in HIV-1 gp41 reveal a correlation between HIV-1-mediated bystander apoptosis and fusion/hemifusion. J. Biol. Chem. 282, 16899-16906
    • (2007) J. Biol. Chem. , vol.282 , pp. 16899-16906
    • Garg, H.1    Joshi, A.2    Freed, E.O.3    Blumenthal, R.4
  • 41
    • 33646442251 scopus 로고    scopus 로고
    • HIV gp41-induced apoptosis is mediated by caspase-3-dependent mitochondrial depolarization, which is inhibited by HIV protease inhibitor nelfinavir
    • Garg, H, and Blumenthal, R. (2006) HIV gp41-induced apoptosis is mediated by caspase-3-dependent mitochondrial depolarization, which is inhibited by HIV protease inhibitor nelfinavir. J. Leukoc. Biol. 79, 351-362
    • (2006) J. Leukoc. Biol. , vol.79 , pp. 351-362
    • Garg, H.1    Blumenthal, R.2
  • 42
    • 18844421132 scopus 로고    scopus 로고
    • Thymic pathogenicity of an HIV-1 envelope is associated with increased CXCR4 binding efficiency and V5-gp41-dependent activity, but not V1/V2-associated CD4 binding efficiency and viral entry
    • Meissner, E. G., Coffield, V. M., and Su, L. (2005) Thymic pathogenicity of an HIV-1 envelope is associated with increased CXCR4 binding efficiency and V5-gp41-dependent activity, but not V1/V2-associated CD4 binding efficiency and viral entry. Virology 336, 184-197
    • (2005) Virology , vol.336 , pp. 184-197
    • Meissner, E.G.1    Coffield, V.M.2    Su, L.3
  • 43
    • 4544238500 scopus 로고    scopus 로고
    • Characterization of a thymus-tropic HIV-1 isolate from a rapid progressor. Role of the envelope
    • Meissner, E. G., Duus, K. M., Gao, F., Yu, X. F., and Su, L. (2004) Characterization of a thymus-tropic HIV-1 isolate from a rapid progressor. Role of the envelope. Virology 328, 74-88
    • (2004) Virology , vol.328 , pp. 74-88
    • Meissner, E.G.1    Duus, K.M.2    Gao, F.3    Yu, X.F.4    Su, L.5
  • 44
    • 80054688941 scopus 로고    scopus 로고
    • HIV ENV glycoprotein-mediated bystander apoptosis depends on expression of the CCR5 co-receptor at the cell surface and ENV fusogenic activity
    • Joshi, A., Nyakeriga, A. M., Ravi, R., and Garg, H. (2011) HIV ENV glycoprotein-mediated bystander apoptosis depends on expression of the CCR5 co-receptor at the cell surface and ENV fusogenic activity. J. Biol. Chem. 286, 36404-36413
    • (2011) J. Biol. Chem. , vol.286 , pp. 36404-36413
    • Joshi, A.1    Nyakeriga, A.M.2    Ravi, R.3    Garg, H.4
  • 45
    • 0031954686 scopus 로고    scopus 로고
    • Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates ofhuman immunodeficiency virus type 1
    • Platt, E. J., Wehrly, K., Kuhmann, S. E., Chesebro, B., and Kabat, D. (1998) Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates ofhuman immunodeficiency virus type 1. J. Virol. 72, 2855-2864
    • (1998) J. Virol. , vol.72 , pp. 2855-2864
    • Platt, E.J.1    Wehrly, K.2    Kuhmann, S.E.3    Chesebro, B.4    Kabat, D.5
  • 51
    • 79957613599 scopus 로고    scopus 로고
    • MEGA5. Molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods
    • Tamura, K., Peterson, D., Peterson, N., Stecher, G., Nei, M., and Kumar, S. (2011) MEGA5. Molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol. Biol. Evol. 28, 2731-2739
    • (2011) Mol. Biol. Evol. , vol.28 , pp. 2731-2739
    • Tamura, K.1    Peterson, D.2    Peterson, N.3    Stecher, G.4    Nei, M.5    Kumar, S.6
  • 55
    • 0037093644 scopus 로고    scopus 로고
    • Increasing the precision of comparative models with YASARA NOVA. A self-parameterizing force field
    • Krieger, E., Koraimann, G., and Vriend, G. (2002) Increasing the precision of comparative models with YASARA NOVA. A self-parameterizing force field. Proteins 47, 393-402
    • (2002) Proteins , vol.47 , pp. 393-402
    • Krieger, E.1    Koraimann, G.2    Vriend, G.3
  • 57
    • 28644432877 scopus 로고    scopus 로고
    • Very fast empirical prediction and rationalization of protein pKa values
    • Li, H., Robertson, A. D., and Jensen, J. H. (2005) Very fast empirical prediction and rationalization of protein pKa values. Proteins 61, 704-721
    • (2005) Proteins , vol.61 , pp. 704-721
    • Li, H.1    Robertson, A.D.2    Jensen, J.H.3
  • 58
    • 13744252890 scopus 로고    scopus 로고
    • MAFFT version 5. Improvement in accuracy of multiple sequence alignment
    • Katoh, K., Kuma, K., Toh, H., and Miyata, T. (2005) MAFFT version 5. Improvement in accuracy of multiple sequence alignment. Nucleic Acids Res. 33, 511-518
    • (2005) Nucleic Acids Res. , vol.33 , pp. 511-518
    • Katoh, K.1    Kuma, K.2    Toh, H.3    Miyata, T.4
  • 60
    • 0034654568 scopus 로고    scopus 로고
    • Caspase-dependent apoptosis of cells expressing the chemokine receptor CXCR4 is induced by cell membrane-associated human immunodeficiency virus type 1 envelope glycoprotein (gp120)
    • Biard-Piechaczyk, M., Robert-Hebmann, V., Richard, V., Roland, J., Hipskind, R. A., and Devaux, C. (2000) Caspase-dependent apoptosis of cells expressing the chemokine receptor CXCR4 is induced by cell membrane-associated human immunodeficiency virus type 1 envelope glycoprotein (gp120). Virology 268, 329-344
    • (2000) Virology , vol.268 , pp. 329-344
    • Biard-Piechaczyk, M.1    Robert-Hebmann, V.2    Richard, V.3    Roland, J.4    Hipskind, R.A.5    Devaux, C.6
  • 61
    • 70349204182 scopus 로고    scopus 로고
    • Altered bystander apoptosis induction and pathogenesis of enfuvirtide-resistant HIV type 1 Env mutants
    • Garg, H., Joshi, A., and Blumenthal, R. (2009) Altered bystander apoptosis induction and pathogenesis of enfuvirtide-resistant HIV type 1 Env mutants. AIDS Res. Hum. Retroviruses 25, 811-817
    • (2009) AIDS Res. Hum. Retroviruses , vol.25 , pp. 811-817
    • Garg, H.1    Joshi, A.2    Blumenthal, R.3
  • 65
    • 35648983524 scopus 로고    scopus 로고
    • Improved prediction of coreceptor usage and phenotype of HIV-1 based on combined features of V3 loop sequence using random forest
    • Xu, S., Huang, X., Xu, H, and Zhang, C. (2007) Improved prediction of coreceptor usage and phenotype of HIV-1 based on combined features of V3 loop sequence using random forest. J. Microbiol. 45, 441-446
    • (2007) J. Microbiol. , vol.45 , pp. 441-446
    • Xu, S.1    Huang, X.2    Xu, H.3    Zhang, C.4
  • 67
    • 33845882991 scopus 로고    scopus 로고
    • Sequence comparison by sequence harmony identifies subtype-specific functional sites
    • Pirovano, W., Feenstra, K. A., and Heringa, J. (2006) Sequence comparison by sequence harmony identifies subtype-specific functional sites. Nucleic Acids Res. 34, 6540-6548
    • (2006) Nucleic Acids Res. , vol.34 , pp. 6540-6548
    • Pirovano, W.1    Feenstra, K.A.2    Heringa, J.3
  • 68
    • 53849093041 scopus 로고    scopus 로고
    • Role of HIV Gp41 mediated fusion/hemifusion in bystander apoptosis
    • Garg, H, and Blumenthal, R. (2008) Role of HIV Gp41 mediated fusion/hemifusion in bystander apoptosis. CellMol. Life Sci. 65, 3134-3144
    • (2008) CellMol. Life Sci. , vol.65 , pp. 3134-3144
    • Garg, H.1    Blumenthal, R.2
  • 70
    • 0028109087 scopus 로고
    • Indirect mechanisms of HIV pathogenesis. How does HIV kill T cells?
    • Finkel, T. H., and Banda, N. K. (1994) Indirect mechanisms of HIV pathogenesis. How does HIV kill T cells? Curr. Opin. Immunol. 6, 605-615
    • (1994) Curr. Opin. Immunol. , vol.6 , pp. 605-615
    • Finkel, T.H.1    Banda, N.K.2
  • 72
    • 33846431248 scopus 로고    scopus 로고
    • Mechanisms of CD4 T-cell depletion triggered by HIV-1 viral proteins
    • Varbanov, M., Espert, L., and Biard-Piechaczyk, M. (2006) Mechanisms of CD4 T-cell depletion triggered by HIV-1 viral proteins. AIDS Rev. 8, 221-236
    • (2006) AIDS Rev. , vol.8 , pp. 221-236
    • Varbanov, M.1    Espert, L.2    Biard-Piechaczyk, M.3
  • 77
    • 74249089192 scopus 로고    scopus 로고
    • Escape from autologous humoral immunity of HIV-1 is not associated with a decrease in replicative capacity
    • Bunnik, E. M., Lobbrecht, M. S., Van Nuenen, A. C, and Schuitemaker, H. (2010) Escape from autologous humoral immunity of HIV-1 is not associated with a decrease in replicative capacity. Virology 397, 224-230
    • (2010) Virology , vol.397 , pp. 224-230
    • Bunnik, E.M.1    Lobbrecht, M.S.2    Van Nuenen, A.C.3    Schuitemaker, H.4
  • 78
    • 4644277015 scopus 로고    scopus 로고
    • Apoptosis of bystander T cells induced by human immunodeficiency virus type 1 with increased envelope/receptor affinity and coreceptor binding site exposure
    • Holm, G. H, Zhang, C, Gorry, P. R., Peden, K., Schols, D., De Clercq, E., and Gabuzda, D. (2004) Apoptosis of bystander T cells induced by human immunodeficiency virus type 1 with increased envelope/receptor affinity and coreceptor binding site exposure. J. Virol. 78, 4541-4551
    • (2004) J. Virol. , vol.78 , pp. 4541-4551
    • Holm, G.H.1    Zhang, C.2    Gorry, P.R.3    Peden, K.4    Schols, D.5    De Clercq, E.6    Gabuzda, D.7
  • 79
    • 33750698659 scopus 로고    scopus 로고
    • Fusion-induced apoptosis contributes to thymocyte depletion by a pathogenic human immunodeficiency virus type 1 envelope in the human thymus
    • Meissner, E. G., Zhang, L., Jiang, S., and Su, L. (2006) Fusion-induced apoptosis contributes to thymocyte depletion by a pathogenic human immunodeficiency virus type 1 envelope in the human thymus. J. Virol. 80, 11019-11030
    • (2006) J. Virol. , vol.80 , pp. 11019-11030
    • Meissner, E.G.1    Zhang, L.2    Jiang, S.3    Su, L.4
  • 80
    • 19144365480 scopus 로고    scopus 로고
    • Relation between changes in cellular load, evolution of viral phenotype, and the clonal composition of virus populations in the course of human immunodeficiency virus type 1 infection
    • Koot, M., Van 't Wout, A. B., Kootstra, N. A., De Goede, R. E., Tersmette, M., and Schuitemaker, H. (1996) Relation between changes in cellular load, evolution of viral phenotype, and the clonal composition of virus populations in the course of human immunodeficiency virus type 1 infection. J. Infect. Dis. 173, 349-354
    • (1996) J. Infect. Dis. , vol.173 , pp. 349-354
    • Koot, M.1    Van'T Wout, A.B.2    Kootstra, N.A.3    De Goede, R.E.4    Tersmette, M.5    Schuitemaker, H.6
  • 81
    • 0031875687 scopus 로고    scopus 로고
    • Emergence of syncytium-inducing human immunodeficiency virus type 1 variants coincides with a transient increase in viral RNA level and is an independent predictor for progression to AIDS
    • Spijkerman, I., De Wolf, F., Langendam, M., Schuitemaker, H, and Coutinho, R. (1998) Emergence of syncytium-inducing human immunodeficiency virus type 1 variants coincides with a transient increase in viral RNA level and is an independent predictor for progression to AIDS. J. Infect. Dis. 178, 397-403
    • (1998) J. Infect. Dis. , vol.178 , pp. 397-403
    • Spijkerman, I.1    De Wolf, F.2    Langendam, M.3    Schuitemaker, H.4    Coutinho, R.5
  • 83
    • 0028125248 scopus 로고
    • Rapid-high, syncytium-inducing isolates of human immunodeficiency virus type 1 induce cytopathicity in the human thymus of the SCID-hu mouse
    • Kaneshima, H., Su, L., Bonyhadi, M. L., Connor, R. I., Ho, D. D., and McCune, J. M. (1994) Rapid-high, syncytium-inducing isolates of human immunodeficiency virus type 1 induce cytopathicity in the human thymus of the SCID-hu mouse. J. Virol. 68, 8188-8192
    • (1994) J. Virol. , vol.68 , pp. 8188-8192
    • Kaneshima, H.1    Su, L.2    Bonyhadi, M.L.3    Connor, R.I.4    Ho, D.D.5    McCune, J.M.6
  • 85
    • 0032957785 scopus 로고    scopus 로고
    • Changes in human immunodeficiency virus type 1 envelope glycoproteins responsible for the pathogenicity of a multiply passaged simian-human immunodeficiency virus (SHIV-HXBc2)
    • Cayabyab, M., Karlsson, G. B., Etemad-Moghadam, B. A., Hofmann, W., Steenbeke, T., Halloran, M., Fanton, J. W., Axthelm, M. K., Letvin, N. L., and Sodroski, J. G. (1999) Changes in human immunodeficiency virus type 1 envelope glycoproteins responsible for the pathogenicity of a multiply passaged simian-human immunodeficiency virus (SHIV-HXBc2). J. Virol. 73, 976-984
    • (1999) J. Virol. , vol.73 , pp. 976-984
    • Cayabyab, M.1    Karlsson, G.B.2    Etemad-Moghadam, B.A.3    Hofmann, W.4    Steenbeke, T.5    Halloran, M.6    Fanton, J.W.7    Axthelm, M.K.8    Letvin, N.L.9    Sodroski, J.G.10
  • 86
    • 0033766295 scopus 로고    scopus 로고
    • Importance of membrane fusion mediated by human immunodeficiency virus envelope glycoproteins for lysis of primary CD4-positive T cells
    • La Bonte, J. A., Patel, T., Hofmann, W., and Sodroski, J. (2000) Importance of membrane fusion mediated by human immunodeficiency virus envelope glycoproteins for lysis of primary CD4-positive T cells. J. Virol. 74, 10690-10698
    • (2000) J. Virol. , vol.74 , pp. 10690-10698
    • La Bonte, J.A.1    Patel, T.2    Hofmann, W.3    Sodroski, J.4
  • 87
    • 0033994315 scopus 로고    scopus 로고
    • Envelope glycoprotein determinants of increased fusogenicity in a pathogenic simian-human immunodeficiency virus (SHIV-KB9) passaged in vivo
    • Etemad-Moghadam, B., Sun, Y., Nicholson, E. K., Fernandes, M., Liou, K., Gomila, R., Lee, J., and Sodroski, J. (2000) Envelope glycoprotein determinants of increased fusogenicity in a pathogenic simian-human immunodeficiency virus (SHIV-KB9) passaged in vivo. J. Virol. 74, 4433-4440
    • (2000) J. Virol. , vol.74 , pp. 4433-4440
    • Etemad-Moghadam, B.1    Sun, Y.2    Nicholson, E.K.3    Fernandes, M.4    Liou, K.5    Gomila, R.6    Lee, J.7    Sodroski, J.8
  • 88
    • 0035012787 scopus 로고    scopus 로고
    • Membrane-fusing capacity of the human immunodeficiency virus envelope proteins determines the efficiency of CD+ T-cell depletion in macaques infected by a simian-human immunodeficiency virus
    • Etemad-Moghadam, B., Rhone, D., Steenbeke, T., Sun, Y., Manola, J., Gelman, R., Fanton, J. W., Racz, P., Tenner-Racz, K., Axthelm, M. K., Letvin, N. L., and Sodroski, J. (2001) Membrane-fusing capacity of the human immunodeficiency virus envelope proteins determines the efficiency of CD+ T-cell depletion in macaques infected by a simian-human immunodeficiency virus. J. Virol. 75, 5646-5655
    • (2001) J. Virol. , vol.75 , pp. 5646-5655
    • Etemad-Moghadam, B.1    Rhone, D.2    Steenbeke, T.3    Sun, Y.4    Manola, J.5    Gelman, R.6    Fanton, J.W.7    Racz, P.8    Tenner-Racz, K.9    Axthelm, M.K.10    Letvin, N.L.11    Sodroski, J.12
  • 90
    • 84869103380 scopus 로고    scopus 로고
    • A machine learning approach for identifying amino acid signatures in the HIV env gene predictive of dementia
    • Holman, A. G., and Gabuzda, D. (2012) A machine learning approach for identifying amino acid signatures in the HIV env gene predictive of dementia. PLoS One 7, e49538
    • (2012) PLoS One , vol.7
    • Holman, A.G.1    Gabuzda, D.2
  • 91
    • 78649995429 scopus 로고    scopus 로고
    • HIV Brain Seq DB. A database of annotated HIV envelope sequences from brain and other anatomical sites
    • Holman, A. G., Mefford, M. E., O'Connor, N, and Gabuzda, D. (2010) HIV Brain Seq DB. A database of annotated HIV envelope sequences from brain and other anatomical sites. AIDS Res. Ther. 7, 43
    • (2010) AIDS Res. Ther. , vol.7 , pp. 43
    • Holman, A.G.1    Mefford, M.E.2    O'Connor, N.3    Gabuzda, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.