Icariin decreases the expression of APP and BACE-1 and reduces the β-amyloid burden in an APP transgenic mouse model of Alzheimer's disease

International Journal of Biological Sciences

Volumn 10, Issue 2, 2014, Pages 181-191

  Zhang, Lan ^a   Shen, Cong ^a   Chu, Jin ^a   Zhang, Ruyi ^a   Li, Yali ^a   Li, Lin ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

amyloid; Alzheimer's disease; Amyloid plaque; Amyloid precursor protein; APPV717I transgenic mice; BACE 1; Icariin

Indexed keywords

AMYLOID PRECURSOR PROTEIN; ASPARTIC PROTEINASE; BACE1 PROTEIN, MOUSE; FLAVONOID; ICARIIN; SECRETASE;

ALZHEIMER DISEASE; AMYLOID PLAQUE; ANIMAL; APPV717I TRANSGENIC MICE; ARTICLE; BACE-1; C57BL MOUSE; GENETICS; HIPPOCAMPUS; HUMAN; LEARNING DISORDER; MEMORY DISORDER; METABOLISM; MOUSE; PATHOLOGY; TRANSGENIC MOUSE; Β-AMYLOID;

ALZHEIMER'S DISEASE; AMYLOID PLAQUE; AMYLOID PRECURSOR PROTEIN; APPV717I TRANSGENIC MICE; BACE-1; ICARIIN; Β-AMYLOID;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; FLAVONOIDS; HIPPOCAMPUS; HUMANS; LEARNING DISORDERS; MEMORY DISORDERS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PLAQUE, AMYLOID;

EID: 84893482971     PISSN: 14492288     EISSN: None     Source Type: Journal    
DOI: 10.7150/ijbs.6232     Document Type: Article

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