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Volumn 1843, Issue 4, 2014, Pages 715-724

MEKK3 and TAK1 synergize to activate IKK complex in Helicobacter pylori infection

Author keywords

CagPAI pathogenicity island; I B ; IKK complex; RelA; TRAF6; Type 4 secretion system

Indexed keywords

CAGA PROTEIN; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 3; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UBIQUITIN PROTEIN LIGASE E3;

EID: 84893472411     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2014.01.006     Document Type: Article
Times cited : (36)

References (45)
  • 1
    • 84856377290 scopus 로고    scopus 로고
    • Genetics of inflammation in the gastrointestinal tract and how it can cause cancer
    • McLean M.H., El-Omar E.M. Genetics of inflammation in the gastrointestinal tract and how it can cause cancer. Recent Results Cancer Res. 2011, 185:173-183.
    • (2011) Recent Results Cancer Res. , vol.185 , pp. 173-183
    • McLean, M.H.1    El-Omar, E.M.2
  • 2
    • 79953701623 scopus 로고    scopus 로고
    • Assembly and molecular mode of action of the Helicobacter pylori Cag type IV secretion apparatus
    • Fischer W. Assembly and molecular mode of action of the Helicobacter pylori Cag type IV secretion apparatus. FEBS J. 2011, 278:1203-2112.
    • (2011) FEBS J. , vol.278 , pp. 1203-2112
    • Fischer, W.1
  • 3
    • 0036032194 scopus 로고    scopus 로고
    • Pathogenesis of Helicobacter pylori infection
    • Gerhard M., Rad R., Prinz C., Naumann M. Pathogenesis of Helicobacter pylori infection. Helicobacter 2002, 7(Suppl. 1):17-23.
    • (2002) Helicobacter , vol.7 , Issue.SUPPL. 1 , pp. 17-23
    • Gerhard, M.1    Rad, R.2    Prinz, C.3    Naumann, M.4
  • 4
    • 0028961743 scopus 로고
    • Interleukin-8 response of gastric epithelial cell lines to Helicobacter pylori stimulation in vitro
    • Sharma S.A., Tummuru M.K., Miller G.G., Blaser M.J. Interleukin-8 response of gastric epithelial cell lines to Helicobacter pylori stimulation in vitro. Infect. Immun. 1995, 63:1681-1687.
    • (1995) Infect. Immun. , vol.63 , pp. 1681-1687
    • Sharma, S.A.1    Tummuru, M.K.2    Miller, G.G.3    Blaser, M.J.4
  • 5
    • 0028802245 scopus 로고
    • Induction of interleukin-8 secretion from gastric epithelial cells by a cagA negative isogenic mutant of Helicobacter pylori
    • Crabtree J.E., Xiang Z., Lindley I.J., Tompkins D.S., Rappuoli R., Covacci A. Induction of interleukin-8 secretion from gastric epithelial cells by a cagA negative isogenic mutant of Helicobacter pylori. J. Clin. Pathol. 1995, 48:967-969.
    • (1995) J. Clin. Pathol. , vol.48 , pp. 967-969
    • Crabtree, J.E.1    Xiang, Z.2    Lindley, I.J.3    Tompkins, D.S.4    Rappuoli, R.5    Covacci, A.6
  • 6
    • 0032030668 scopus 로고    scopus 로고
    • Activation of IL-8 gene expression by Helicobacter pylori is regulated by transcription factor nuclear factor-kappa B in gastric epithelial cells
    • Sharma S.A., Tummuru M.K., Blaser M.J., Kerr L.D. Activation of IL-8 gene expression by Helicobacter pylori is regulated by transcription factor nuclear factor-kappa B in gastric epithelial cells. J. Immunol. 1998, 160:2401-2407.
    • (1998) J. Immunol. , vol.160 , pp. 2401-2407
    • Sharma, S.A.1    Tummuru, M.K.2    Blaser, M.J.3    Kerr, L.D.4
  • 8
    • 0030772159 scopus 로고    scopus 로고
    • Helicobacter pylori infection activates NF-kappaB in gastric epithelial cell
    • Keates S., Hitti Y.S., Upton M., Kelly C.P. Helicobacter pylori infection activates NF-kappaB in gastric epithelial cell. Gastroenterology 1997, 113:1099-1109.
    • (1997) Gastroenterology , vol.113 , pp. 1099-1109
    • Keates, S.1    Hitti, Y.S.2    Upton, M.3    Kelly, C.P.4
  • 9
    • 0035725211 scopus 로고    scopus 로고
    • Systematic mutagenesis of the Helicobacter pylori cag pathogenicity island: essential genes for CagA translocation in host cells and induction of interleukin-8
    • Fischer W., Püls J., Buhrdorf R., Gebert B., Odenbreit S., Haas R. Systematic mutagenesis of the Helicobacter pylori cag pathogenicity island: essential genes for CagA translocation in host cells and induction of interleukin-8. Mol. Microbiol. 2001, 42:1337-1348.
    • (2001) Mol. Microbiol. , vol.42 , pp. 1337-1348
    • Fischer, W.1    Püls, J.2    Buhrdorf, R.3    Gebert, B.4    Odenbreit, S.5    Haas, R.6
  • 12
    • 33644777528 scopus 로고    scopus 로고
    • Helicobacter pylori induces IκB kinase α nuclear translocation and chemokine production in gastric epithelial cells
    • Hirata Y., Maeda S., Ohmae T., Shibata W., Yanai A., Ogura K., Yoshida H., Kawabe T., Omata M. Helicobacter pylori induces IκB kinase α nuclear translocation and chemokine production in gastric epithelial cells. Infect. Immun. 2006, 74:1452-1461.
    • (2006) Infect. Immun. , vol.74 , pp. 1452-1461
    • Hirata, Y.1    Maeda, S.2    Ohmae, T.3    Shibata, W.4    Yanai, A.5    Ogura, K.6    Yoshida, H.7    Kawabe, T.8    Omata, M.9
  • 13
  • 14
    • 0034671936 scopus 로고    scopus 로고
    • P21-activated kinase 1 activates the nuclear factor kB (NF-kB)-inducing kinase-IkB kinases NF-kB pathway and proinflammatory cytokines in Helicobacter pylori infection
    • Foryst-Ludwig A., Naumann M. p21-activated kinase 1 activates the nuclear factor kB (NF-kB)-inducing kinase-IkB kinases NF-kB pathway and proinflammatory cytokines in Helicobacter pylori infection. J. Biol. Chem. 2000, 275:39779-39785.
    • (2000) J. Biol. Chem. , vol.275 , pp. 39779-39785
    • Foryst-Ludwig, A.1    Naumann, M.2
  • 15
    • 79955420331 scopus 로고    scopus 로고
    • Helicobacter pylori-induced tyrosine phosphorylation of IKKb contributes to NF-kB activation
    • Rieke C., Papendieck A., Sokolova O., Naumann M. Helicobacter pylori-induced tyrosine phosphorylation of IKKb contributes to NF-kB activation. Biol. Chem. 2011, 392:387-393.
    • (2011) Biol. Chem. , vol.392 , pp. 387-393
    • Rieke, C.1    Papendieck, A.2    Sokolova, O.3    Naumann, M.4
  • 16
    • 82355173122 scopus 로고    scopus 로고
    • Microbial-induced immunomodulation by targeting the NF-kB system
    • Neish A., Naumann M. Microbial-induced immunomodulation by targeting the NF-kB system. Trends Microbiol. 2011, 19:596-605.
    • (2011) Trends Microbiol. , vol.19 , pp. 596-605
    • Neish, A.1    Naumann, M.2
  • 17
    • 30644468837 scopus 로고    scopus 로고
    • The PAK1 autoregulatory domain is required for interaction with NIK in Helicobacter pylori-induced NF-kB activation
    • Neumann M., Foryst-Ludwig A., Klar S., Schweitzer K., Naumann M. The PAK1 autoregulatory domain is required for interaction with NIK in Helicobacter pylori-induced NF-kB activation. Biol. Chem. 2006, 387:79-86.
    • (2006) Biol. Chem. , vol.387 , pp. 79-86
    • Neumann, M.1    Foryst-Ludwig, A.2    Klar, S.3    Schweitzer, K.4    Naumann, M.5
  • 18
    • 0034235373 scopus 로고    scopus 로고
    • H. pylori activates NF-kappaB through a signaling pathway involving IkappaB kinases, NF-kappaB-inducing kinase, TRAF2, and TRAF6 in gastric cancer cells
    • Maeda S., Yoshida H., Ogura K., Mitsuno Y., Hirata Y., Yamaji Y., Akanuma M., Shiratori Y., Omata M. H. pylori activates NF-kappaB through a signaling pathway involving IkappaB kinases, NF-kappaB-inducing kinase, TRAF2, and TRAF6 in gastric cancer cells. Gastroenterology 2000, 119:97-108.
    • (2000) Gastroenterology , vol.119 , pp. 97-108
    • Maeda, S.1    Yoshida, H.2    Ogura, K.3    Mitsuno, Y.4    Hirata, Y.5    Yamaji, Y.6    Akanuma, M.7    Shiratori, Y.8    Omata, M.9
  • 19
    • 33644838832 scopus 로고    scopus 로고
    • MyD88 and TNF receptor-associated factor 6 are critical signal transducers in Helicobacter pylori-infected human epithelial cells
    • Hirata Y., Ohmae T., Shibata W., Maeda S., Ogura K., Yoshida H., Kawabe T., Omata M. MyD88 and TNF receptor-associated factor 6 are critical signal transducers in Helicobacter pylori-infected human epithelial cells. J. Immunol. 2006, 176:3796-3803.
    • (2006) J. Immunol. , vol.176 , pp. 3796-3803
    • Hirata, Y.1    Ohmae, T.2    Shibata, W.3    Maeda, S.4    Ogura, K.5    Yoshida, H.6    Kawabe, T.7    Omata, M.8
  • 21
    • 84879891375 scopus 로고    scopus 로고
    • Ca2+/calmodulin-dependent kinase II contributes to inhibitor of nuclear factor-kappa B kinase complex activation in Helicobacter pylori infection
    • Maubach G., Sokolova O., Wolfien M., Rothkötter H.J., Naumann M. Ca2+/calmodulin-dependent kinase II contributes to inhibitor of nuclear factor-kappa B kinase complex activation in Helicobacter pylori infection. Int. J. Cancer 2013, 133:1507-1512.
    • (2013) Int. J. Cancer , vol.133 , pp. 1507-1512
    • Maubach, G.1    Sokolova, O.2    Wolfien, M.3    Rothkötter, H.J.4    Naumann, M.5
  • 22
    • 77958165564 scopus 로고    scopus 로고
    • What a disorder: pro-inflammatory signaling pathways induced by Helicobacter pylori
    • Backert S., Naumann M. What a disorder: pro-inflammatory signaling pathways induced by Helicobacter pylori. Trends Microbiol. 2010, 18:479-486.
    • (2010) Trends Microbiol. , vol.18 , pp. 479-486
    • Backert, S.1    Naumann, M.2
  • 24
    • 0037732638 scopus 로고    scopus 로고
    • Helicobacter pylori CagA protein targets the c-Met receptor and enhances the motogenic response
    • Churin Y., Al-Ghoul L., Kepp O., Meyer T.F., Birchmeier W., Naumann M. Helicobacter pylori CagA protein targets the c-Met receptor and enhances the motogenic response. J. Cell Biol. 2003, 161:249-255.
    • (2003) J. Cell Biol. , vol.161 , pp. 249-255
    • Churin, Y.1    Al-Ghoul, L.2    Kepp, O.3    Meyer, T.F.4    Birchmeier, W.5    Naumann, M.6
  • 25
    • 84887613180 scopus 로고    scopus 로고
    • Helicobacter pylori induces type 4 secretion system-dependent, but CagA-independent activation of IκBs and NF-κB/RelA at early time points
    • Sokolova O., Borgmann M., Rieke C., Schweitzer K., Rothkötter H.J., Naumann M. Helicobacter pylori induces type 4 secretion system-dependent, but CagA-independent activation of IκBs and NF-κB/RelA at early time points. Int. J. Med. Microbiol. 2013, 303:548-552.
    • (2013) Int. J. Med. Microbiol. , vol.303 , pp. 548-552
    • Sokolova, O.1    Borgmann, M.2    Rieke, C.3    Schweitzer, K.4    Rothkötter, H.J.5    Naumann, M.6
  • 26
    • 57649187556 scopus 로고    scopus 로고
    • Helicobacter pylori suppresses GSK3b to promote β-catenin activity
    • Sokolova O., Bozko P.M., Naumann M. Helicobacter pylori suppresses GSK3b to promote β-catenin activity. J. Biol. Chem. 2008, 283:29367-29374.
    • (2008) J. Biol. Chem. , vol.283 , pp. 29367-29374
    • Sokolova, O.1    Bozko, P.M.2    Naumann, M.3
  • 27
    • 0037663730 scopus 로고    scopus 로고
    • Structural definition on the surface of Helicobacter pylori type IV secretion apparatus
    • Tanaka J., Suzuki T., Mimuro H., Sasakawa C. Structural definition on the surface of Helicobacter pylori type IV secretion apparatus. Cell. Microbiol. 2003, 5:395-404.
    • (2003) Cell. Microbiol. , vol.5 , pp. 395-404
    • Tanaka, J.1    Suzuki, T.2    Mimuro, H.3    Sasakawa, C.4
  • 29
  • 31
    • 0033634977 scopus 로고    scopus 로고
    • TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway
    • Takaesu G., S.Kishida, Hiyama A., Yamaguchi K., Shibuya H., Irie K., Ninomiya-Tsuji J., Matsumoto K. TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway. Mol. Cell 2000, 5:649-658.
    • (2000) Mol. Cell , vol.5 , pp. 649-658
    • Takaesu, G.1    Kishida, S.2    Hiyama, A.3    Yamaguchi, K.4    Shibuya, H.5    Irie, K.6    Ninomiya-Tsuji, J.7    Matsumoto, K.8
  • 32
    • 33845768987 scopus 로고    scopus 로고
    • Integrating cell-signalling pathways with NF-kappaB and IKK function
    • Perkins N.D. Integrating cell-signalling pathways with NF-kappaB and IKK function. Nat. Rev. Mol. Cell Biol. 2007, 8:49-62.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 49-62
    • Perkins, N.D.1
  • 33
    • 0038143356 scopus 로고    scopus 로고
    • In vivo identification of inducible phosphoacceptors in the IKKgamma/NEMO subunit of human IkappaB kinase
    • Pennington R.S., Ballard B.J.W. In vivo identification of inducible phosphoacceptors in the IKKgamma/NEMO subunit of human IkappaB kinase. J. Biol. Chem. 2003, 278:19642-19648.
    • (2003) J. Biol. Chem. , vol.278 , pp. 19642-19648
    • Pennington, R.S.1    Ballard, B.J.W.2
  • 34
    • 0037024696 scopus 로고    scopus 로고
    • Regulation of Ikappa B kinase (IKK)gamma/NEMO function by IKKbeta-mediated phosphorylation
    • Prajapati S., Gaynor R.B. Regulation of Ikappa B kinase (IKK)gamma/NEMO function by IKKbeta-mediated phosphorylation. J. Biol. Chem. 2002, 277:24331-24339.
    • (2002) J. Biol. Chem. , vol.277 , pp. 24331-24339
    • Prajapati, S.1    Gaynor, R.B.2
  • 35
    • 0036408735 scopus 로고    scopus 로고
    • Phosphorylation of the stress-activated protein kinase, MEKK3, at serine 166
    • Adams D.G., Sachs N.A., Vaillancourt R.R. Phosphorylation of the stress-activated protein kinase, MEKK3, at serine 166. Arch. Biochem. Biophys. 2002, 407:103-116.
    • (2002) Arch. Biochem. Biophys. , vol.407 , pp. 103-116
    • Adams, D.G.1    Sachs, N.A.2    Vaillancourt, R.R.3
  • 36
    • 45149086931 scopus 로고    scopus 로고
    • Phosphorylation of MEKK3 at threonine 294 promotes 14-3-3 association to inhibit nuclear factor kappaB activation
    • Matitau A.E., Scheid M.P. Phosphorylation of MEKK3 at threonine 294 promotes 14-3-3 association to inhibit nuclear factor kappaB activation. J. Biol. Chem. 2008, 283:13261-13268.
    • (2008) J. Biol. Chem. , vol.283 , pp. 13261-13268
    • Matitau, A.E.1    Scheid, M.P.2
  • 37
    • 77950891312 scopus 로고    scopus 로고
    • Phosphorylation of Thr-516 and Ser-520 in the kinase activation loop of MEKK3 is required for lysophosphatidic acid-mediated optimal IkappaB kinase beta (IKKbeta)/nuclear factor-kappaB (NF-kappaB) activation
    • Sun W., Ge N., Yu Y., Burlingame S., Li X., Zhang M., Ye S., Fu S., Yang J. Phosphorylation of Thr-516 and Ser-520 in the kinase activation loop of MEKK3 is required for lysophosphatidic acid-mediated optimal IkappaB kinase beta (IKKbeta)/nuclear factor-kappaB (NF-kappaB) activation. J. Biol. Chem. 2010, 285:7911-7918.
    • (2010) J. Biol. Chem. , vol.285 , pp. 7911-7918
    • Sun, W.1    Ge, N.2    Yu, Y.3    Burlingame, S.4    Li, X.5    Zhang, M.6    Ye, S.7    Fu, S.8    Yang, J.9
  • 38
    • 84866731086 scopus 로고    scopus 로고
    • Targeting of TAK1 in inflammatory disorders and cancer
    • Sakurai H. Targeting of TAK1 in inflammatory disorders and cancer. Trends Pharmacol. Sci. 2012, 33:522-530.
    • (2012) Trends Pharmacol. Sci. , vol.33 , pp. 522-530
    • Sakurai, H.1
  • 39
    • 84863043792 scopus 로고    scopus 로고
    • Reciprocal inhibition between the transforming growth factor-β-activated kinase 1 (TAK1) and apoptosis signal-regulating kinase 1 (ASK1) mitogen-activated protein kinase kinase kinases and its suppression by TAK1-binding protein 2 (TAB2), an adapter protein for TAK1
    • Kim S.Y., Shim J.H., Chun E., Lee K.Y. Reciprocal inhibition between the transforming growth factor-β-activated kinase 1 (TAK1) and apoptosis signal-regulating kinase 1 (ASK1) mitogen-activated protein kinase kinase kinases and its suppression by TAK1-binding protein 2 (TAB2), an adapter protein for TAK1. J. Biol. Chem. 2012, 287:3381-3391.
    • (2012) J. Biol. Chem. , vol.287 , pp. 3381-3391
    • Kim, S.Y.1    Shim, J.H.2    Chun, E.3    Lee, K.Y.4
  • 40
    • 84862761186 scopus 로고    scopus 로고
    • Diverse ubiquitin signaling in NF-κB activation
    • Iwai K. Diverse ubiquitin signaling in NF-κB activation. Trends Cell Biol. 2012, 22:355-364.
    • (2012) Trends Cell Biol. , vol.22 , pp. 355-364
    • Iwai, K.1
  • 41
    • 84855292725 scopus 로고    scopus 로고
    • Polyubiquitination of transforming growth factor β (TGFβ)-associated kinase 1 mediates nuclear factor-κB activation in response to different inflammatory stimuli
    • Hamidi A., von Bulow V., Hamidi R., Winssinger N., Barluenga S., Heldin C.H., Landström M. Polyubiquitination of transforming growth factor β (TGFβ)-associated kinase 1 mediates nuclear factor-κB activation in response to different inflammatory stimuli. J. Biol. Chem. 2012, 287:123-133.
    • (2012) J. Biol. Chem. , vol.287 , pp. 123-133
    • Hamidi, A.1    von Bulow, V.2    Hamidi, R.3    Winssinger, N.4    Barluenga, S.5    Heldin, C.H.6    Landström, M.7
  • 42
    • 82755190610 scopus 로고    scopus 로고
    • Tripartite motif 8 (TRIM8) modulates TNFα- and IL-1β-triggered NF-κB activation by targeting TAK1 for K63-linked polyubiquitination
    • Li Q., Yan J., Mao A.P., Li C., Ran Y., Shu H.B., Wang Y.Y. Tripartite motif 8 (TRIM8) modulates TNFα- and IL-1β-triggered NF-κB activation by targeting TAK1 for K63-linked polyubiquitination. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:19341-19346.
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 19341-19346
    • Li, Q.1    Yan, J.2    Mao, A.P.3    Li, C.4    Ran, Y.5    Shu, H.B.6    Wang, Y.Y.7
  • 45
    • 84859973888 scopus 로고    scopus 로고
    • Lys48-linked TAK1 polyubiquitination at lysine-72 downregulates TNFα-induced NF-κB activation via mediating TAK1 degradation
    • Fan Y., Shi Y., Liu S., Mao R., An L., Zhao Y., Zhang H., Zhang F., Xu G., Qin J., Yang J. Lys48-linked TAK1 polyubiquitination at lysine-72 downregulates TNFα-induced NF-κB activation via mediating TAK1 degradation. Cell. Signal. 2012, 24:1381-1389.
    • (2012) Cell. Signal. , vol.24 , pp. 1381-1389
    • Fan, Y.1    Shi, Y.2    Liu, S.3    Mao, R.4    An, L.5    Zhao, Y.6    Zhang, H.7    Zhang, F.8    Xu, G.9    Qin, J.10    Yang, J.11


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