In vivo identification of inducible phosphoacceptors in the IKKγ/NEMO subunit of human IκB kinase

Journal of Biological Chemistry

Volumn 278, Issue 22, 2003, Pages 19642-19648

  Carter, Robert S ^b   Pennington, Kevin N ^b   Ungurait, Bradley J ^b   Ballard, Dean W ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; CELLS; CYTOLOGY; GENETIC ENGINEERING; METABOLISM;

PHOSPHORYLATION;

PROTEINS;

I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ONCOPROTEIN; TAX PROTEIN; TUMOR NECROSIS FACTOR ALPHA; CARRIER PROTEIN; IKBKG PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE;

ANIMAL CELL; ARTICLE; CATALYSIS; CELL CYCLE; CONTROLLED STUDY; EMBRYO; GENE MUTATION; GENETIC CODE; GENETIC TRANSCRIPTION; IMMUNE DEFICIENCY; IMMUNE SYSTEM; IN VIVO STUDY; ISOTOPE LABELING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TARGETING; SIGNAL TRANSDUCTION; ZINC FINGER MOTIF; CELL LINE; CHEMISTRY; METABOLISM; PHOSPHORYLATION;

ANIMALIA;

CARRIER PROTEINS; CELL LINE; I-KAPPA B KINASE; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES;

EID: 0038143356     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M301705200     Document Type: Article

References (40)

1. Ghosh, S., May, M. J., and Kopp, E. B. (1998) Annu. Rev. Immunol. 16, 225-260
2. Sha, W. C. (1998) J. Exp. Med. 187, 143-146
3. Pahl, H. L. (1999) Oncogene 18, 6853-6866
4. Hawiger, J., Veach, R. A., Liu, X. Y., Timmons, S., and Ballard, D. W. (1999) Blood 94, 1711-1716
5. Chu, Z. L., DiDonato, J. A., Hawiger, J., and Ballard, D. W. (1998) J. Biol. Chem. 273, 15891-15894
6. Sun, S. C., and Ballard, D. W. (1999) Oncogene 18, 6948-6958
7. Karin, M. (1999) Oncogene 18, 6867-6874
8. Zandi, E., and Karin, M. (1999) Mol. Cell. Biol. 19, 4547-4551
9. Delhase, M., Hayakawa, M., Chen, Y., and Karin, M. (1999) Science 284, 309-313
10. Yamaoka, S., Courtois, G., Bessia, C., Whiteside, S. T., Weil, R., Agou, F., Kirk, H. E., Kay, R. J., and Israel, A. (1998) Cell 93, 1231-1240
11. Mercurio, F., Murray, B. W., Shevchenko, A., Bennett, B. L., Young, D. B., Li, J. W., Pascual, G., Motiwala, A., Zhu, H., Mann, M., and Manning, A. M. (1999) Mol. Cell. Biol. 19, 1526-1538
12. Rothwarf, D. M., Zandi, E., Natoli, G., and Karin, M. (1998) Nature 395, 297-300
13. Li, Y., Kang, J., Friedman, J., Tarassishin, L., Ye, J., Kovalenko, A., Wallach, D., and Horwitz, M. S. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 1042-1047
14. Harhaj, E. W., Good, L., Xiao, G., Uhlik, M., Cvijic, M. E., Rivera-Walsh, I., and Sun, S. C. (2000) Oncogene 19, 1448-1456
15. Courtois, G., Smahi, A., and Israel, A. (2001) Trends Mol. Med. 7, 427-430
16. Ghosh, S., and Karin, M. (2002) Cell 109, (suppl.) 81-96
17. Prajapati, S., and Gaynor, R. B. (2002) J. Biol. Chem. 277, 24331-24339
18. Tarassishin, L., and Horwitz, M. S. (2001) Biochem. Biophys. Res. Commun. 285, 555-560
19. Carter, R. S., Geyer, B. C., Xie, M., Acevedo-Suarez, C. A., and Ballard, D. W. (2001) J. Biol. Chem. 276, 24445-24448
20. Smith, M. R., and Greene, W. C. (1990) Genes Dev. 4, 1875-1885
21. Mercurio, F., Zhu, H., Murray, B. W., Shevchenko, A., Bennett, B. L., Li, J., Young, D. B., Barbosa, M., Mann, M., Manning, A., and Rao, A. (1997) Science 278, 860-866
22. Ye, J., Xie, X., Tarassishin, L., and Horwitz, M. S. (2000) J. Biol. Chem. 275, 9882-9889
23. Tartaglia, L. A., and Goeddel, D. V. (1992) J. Biol. Chem. 267, 4304-4307
24. Li, Q., Lu, Q., Hwang, J. Y., Buscher, D., Lee, K. F., Izpisua-Belmonte, J. C., and Verma, I. M. (1999) Genes Dev. 13, 1322-1328
25. Li, Q., Van Antwerp, D., Mercurio, F., Lee, K. F., and Verma, I. M. (1999) Science 284, 321-325
26. DuBridge, R. B., Tang, P., Hsia, H. C., Leong, P. M., Miller, J. H., and Calos, M. P. (1987) Mol. Cell. Biol. 7, 379-387
27. Cullen, B. R. (1987) Methods Enzymol. 152, 684-704
28. Schreiber, E., Matthias, P., Muller, M. M., and Schaffner, W. (1989) Nucleic Acids Res. 17, 6420
29. Luo, K. X., Hurley, T. R., and Sefton, B. M. (1991) Methods Enzymol. 201, 149-152
30. Boyle, W. J., van der Geer, P., and Hunter, T. (1991) Methods Enzymol. 201, 110-149
31. DiDonato, J. A., Hayakawa, M., Rothwarf, D. M., Zandi, E., and Karin, M. (1997) Nature 388, 548-554
32. May, M. J., D'Acquisto, F., Madge, L. A., Glockner, J., Pober, J. S., and Ghosh, S. (2000) Science 289, 1550-1554
33. Chu, Z. L., Shin, Y. A., Yang, J. M., DiDonato, J. A., and Ballard, D. W. (1999) J. Biol. Chem. 274, 15297-15300
34. Devin, A., Cook, A., Lin, Y., Rodriguez, Y., Kelliher, M., and Liu, Z. (2000) Immunity 12, 419-429
35. Zhang, S. Q., Kovalenko, A., Cantarella, G., and Wallach, D. (2000) Immunity 12, 301-311
36. Makris, C., Roberts, J. L., and Karin, M. (2002) Mol. Cell. Biol. 22, 6573-6581
37. Huang, T. T., Feinberg, S. L., Suryanarayanan, S., and Miyamoto, S. (2002) Mol. Cell. Biol. 22, 5813-5825
38. Baeuerle, P. A., and Baltimore, D. (1988) Science 242, 540-546
39. Chen, Z., Hagler, J., Palombella, V. J., Melandri, F., Scherer, D., Ballard, D., and Maniatis, T. (1995) Genes Dev. 9, 1586-1597
40. McFarlane, S. M., Pashmi, G., Connell, M. C., Littlejohn, A. F., Tucker, S. J., Vandenabeele, P., and MacEwan, D. J. (2002) FEBS Lett. 515, 119-126