Ca2+/calmodulin-dependent kinase II contributes to inhibitor of nuclear factor-kappa B kinase complex activation in Helicobacter pylori infection

International Journal of Cancer

Volumn 133, Issue 6, 2013, Pages 1507-1512

  Maubach, Gunter ^a   Sokolova, Olga ^a   Wolfien, Markus ^a   Rothkötter, Hermann Josef ^a   Naumann, Michael ^a  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

calmodulin; gastric cancer; I B ; RelA; type 4 secretion system

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II ALPHA; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II BETA; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II DELTA; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II GAMMA; CALMIDAZOLIUM; CALMODULIN; CARISOPRODOL; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE C; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; BCL10 PROTEIN, HUMAN; CARD10 PROTEIN, HUMAN; CASPASE; CASPASE RECRUITMENT DOMAIN SIGNALING PROTEIN; I KAPPA B KINASE; MALT1 PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TUMOR PROTEIN;

ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; ENZYME INHIBITION; HELICOBACTER INFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; TRANSCRIPTION INITIATION; CELL CULTURE; HELICOBACTER PYLORI; IΚBΑ; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; STOMACH CANCER; TYPE IV SECRETION SYSTEM;

CALMODULIN; GASTRIC CANCER; IΚBΑ; RELA; TYPE 4 SECRETION SYSTEM;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CALMODULIN; CARD SIGNALING ADAPTOR PROTEINS; CASPASES; CELLS, CULTURED; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; I-KAPPA B KINASE; NEOPLASM PROTEINS; NF-KAPPA B; PROTEIN KINASE C;

EID: 84879891375     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.28148     Document Type: Article

References (25)

1. Pounder RE, Ng D,. The prevalence of Helicobacter pylori infection in different countries. Aliment Pharmacol Ther 1995; 9 Suppl 2: 33-9.
2. Shanks AM, El-Omar EM,. Helicobacter pylori infection, host genetics and gastric cancer. J Dig Dis 2009; 10: 157-64.
3. Naumann M, Wessler S, Bartsch C, et al. Activation of activator protein 1 and stress response kinases in epithelial cells colonized by helicobacter pylori encoding the cag pathogenicity island. J Biol Chem 1999; 274: 31655-62.
4. Foryst-Ludwig A, Naumann M,. p21-activated kinase 1 activates the nuclear factor kappa B (NF-kappa B)-inducing kinase-Ikappa B kinases NF-kappa B pathway and proinflammatory cytokines in Helicobacter pylori infection. J Biol Chem 2000; 275: 39779-85.
5. Schweitzer K, Sokolova O, Bozko PM, et al. Helicobacter pylori induces NF-[kappa]B independent of CagA. EMBO Rep 2010; 11: 10-1.
6. Backert S, Naumann M,. What a disorder: proinflammatory signaling pathways induced by Helicobacter pylori. Trends Microbiol 2010; 18: 479-86.
7. Oruganti SR, Edin S, Grundstrom C, Grundstrom T,. CaMKII targets Bcl10 in T-cell receptor induced activation of NF-kappaB. Mol Immunol 2011; 48: 1448-60.
8. Thome M, Tschopp J,. TCR-induced NF-κB activation: a crucial role for Carma1, Bcl10 and MALT1. Trends Immunol 2003; 24: 419-24.
9. Delekta PC, Apel IJ, Gu S, et al. Thrombin-dependent NF-{kappa}B activation and monocyte/endothelial adhesion are mediated by the CARMA3.Bcl10.MALT1 signalosome. J Biol Chem 2010; 285: 41432-42.
10. McAllister-Lucas LM, Ruland J, Siu K, et al. CARMA3/Bcl10/MALT1-dependent NF-kappaB activation mediates angiotensin II-responsive inflammatory signaling in nonimmune cells. Proc Natl Acad Sci USA 2007; 104: 139-44.
11. Cummings R, Zhao Y, Jacoby D, et al. Protein Kinase Cδ Mediates Lysophosphatidic Acid-induced NF-κB Activation and interleukin-8 secretion in human bronchial epithelial cells. J Biol Chem 2004; 279: 41085-94.
12. Sun Z, Arendt CW, Ellmeier W, et al. PKC-theta is required for TCR-induced NF-kappaB activation in mature but not immature T lymphocytes. Nature 2000; 404: 402-7.
13. Mahanivong C, Chen HM, Yee SW, et al. Protein kinase C alpha-CARMA3 signaling axis links Ras to NF-kappa B for lysophosphatidic acid-induced urokinase plasminogen activator expression in ovarian cancer cells. Oncogene 2008; 27: 1273-80.
14. Sokolova O, Vieth M, Naumann M,. Protein kinase C isozymes regulate matrix metalloproteinase-1 expression and cell invasion in Helicobacter pylori infection. Gut 2013, 62: 358-367.
15. Hudmon A, Schulman H,. Structure-function of the multifunctional Ca2+/calmodulin-dependent protein kinase II. Biochem J 2002; 364: 593-611.
16. Nozawa Y, Nishihara K, Peek RM, Jr, et al. Identification of a signaling cascade for interleukin-8 production by Helicobacter pylori in human gastric epithelial cells. Biochem Pharmacol 2002; 64: 21-30.
17. Chin D, Means AR,. Calmodulin: a prototypical calcium sensor. Trends Cell Biol 2000; 10: 322-8.
18. Swindells MB, Ikura M,. Pre-formation of the semi-open conformation by the apo-calmodulin C-terminal domain and implications binding IQ-motifs. Nat Struct Biol 1996; 3: 501-4.
19. Carpenter AE, Jones TR, Lamprecht MR, et al. CellProfiler: image analysis software for identifying and quantifying cell phenotypes. Genome Biol 2006; 7: R100.
20. Fischer R, Koller M, Flura M, et al. Multiple divergent mRNAs code for a single human calmodulin. J Biol Chem 1988; 263: 17055-62.
21. Bayer KU, Lohler J, Schulman H, et al. Developmental expression of the CaM kinase II isoforms: ubiquitous gamma- and delta-CaM kinase II are the early isoforms and most abundant in the developing nervous system. Brain Res Mol Brain Res 1999; 70: 147-54.
22. Nozawa Y, Nishihara K, Akizawa Y, et al. Protein kinase C activation by Helicobacter pylori in human gastric epithelial cells limits interleukin-8 production through suppression of extracellular signal-regulated kinase. J Pharmacol Sci 2004; 94: 233-9.
23. Culver C, Sundqvist A, Mudie S, et al. Mechanism of hypoxia-induced NF-kappaB. Mol Cell Biol 2010; 30: 4901-21.
24. Qiao G, Li Z, Molinero L, et al. T-cell receptor-Induced NF-κB activation is negatively regulated by E3 Ubiquitin ligase Cbl-b. Mol Cell Biol 2008; 28: 2470-80.
25. Wang D, You Y, Lin PC, et al. Bcl10 plays a critical role in NF-kappaB activation induced by G protein-coupled receptors. Proc Natl Acad Sci USA 2007; 104: 145-50.