6-Shogaol inhibits chondrocytes' innate immune responses and cathepsin-K activity

Molecular Nutrition and Food Research

Volumn 58, Issue 2, 2014, Pages 256-266

  Villalvilla, Amanda ^a   da Silva, Jame's A ^b,d   Largo, Raquel ^a   Gualillo, Oreste ^c   Vieira, Paulo Cezar ^b   Herrero Beaumont, Gabriel ^a   Gómez, Rodolfo ^a  

^a 28400 Madrid   (Spain)

^b FEDERAL UNIVERSITY OF SÃO CARLOS   (Brazil)

^c Santiago University Clinical Hospital   (Spain)

^d FEDERAL UNIVERSITY OF SERGIPE   (Brazil)

Author keywords

Chondrocytes; Ginger; Inflammation; Osteoarthritis; TLRs

Indexed keywords

ANTIINFLAMMATORY AGENT; CATECHOL DERIVATIVE; CATHEPSIN K; CCL2 PROTEIN, HUMAN; GELATINASE A; GELATINASE B; IL6 PROTEIN, HUMAN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MMP2 PROTEIN, HUMAN; MMP9 PROTEIN, HUMAN; MONOCYTE CHEMOTACTIC PROTEIN 1; MYD88 PROTEIN, HUMAN; MYELOID DIFFERENTIATION FACTOR 88; NITRIC OXIDE; NOS2 PROTEIN, HUMAN; PLANT EXTRACT; SHOGAOL; TLR4 PROTEIN, HUMAN; TOLL LIKE RECEPTOR 4;

ARTICLE; CARTILAGE CELL; CELL CULTURE; CELL SURVIVAL; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; GINGER; HUMAN; INFLAMMATION; INNATE IMMUNITY; METABOLISM; OSTEOARTHRITIS; SIGNAL TRANSDUCTION; TLRS;

CHONDROCYTES; GINGER; INFLAMMATION; OSTEOARTHRITIS; TLRS;

ANTI-INFLAMMATORY AGENTS; CATECHOLS; CATHEPSIN K; CELL SURVIVAL; CELLS, CULTURED; CHEMOKINE CCL2; CHONDROCYTES; GINGER; HUMANS; IMMUNITY, INNATE; INTERLEUKIN-1BETA; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MYELOID DIFFERENTIATION FACTOR 88; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OSTEOARTHRITIS; PLANT EXTRACTS; TOLL-LIKE RECEPTOR 4;

EID: 84893417040     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201200833     Document Type: Article

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