Comparative effects of ginger root (Zingiber officinale Rosc.) on the production of inflammatory mediators in normal and osteoarthrotic sow chondrocytes

Journal of Medicinal Food

Volumn 8, Issue 2, 2005, Pages 149-153

  Shen, Chwan Li ^a   Hong, Kee Jong ^a   Kim, Sung Woo ^a  

^a TEXAS TECH UNIVERSITY   (United States)

Author keywords

Cartilage; Cell culture; Ginger; Osteoarthrosis; Pigs; Sows

Indexed keywords

ANTIRHEUMATIC AGENT; AQUARESIN GINGER; GINGER EXTRACT; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; NITRIC OXIDE; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARTILAGE CELL; CONTROLLED STUDY; GINGER; NONHUMAN; OSTEOARTHRITIS; PLANT ROOT; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; RADIOIMMUNOASSAY; REGRESSION ANALYSIS; SWINE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CARTILAGE, ARTICULAR; CHONDROCYTES; DINOPROSTONE; DISEASE MODELS, ANIMAL; FEMALE; GINGER; NITRIC OXIDE; OSTEOARTHRITIS; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS; PLANTS, MEDICINAL; SWINE; TISSUE CULTURE TECHNIQUES;

BOVINAE; ZINGIBER OFFICINALE;

EID: 22444448068     PISSN: 1096620X     EISSN: None     Source Type: Journal    
DOI: 10.1089/jmf.2005.8.149     Document Type: Article

References (24)

1. Srivastava KC, Mustafa T: Ginger (Zingiber officinale) in rheumatism and musculoskeletal disorders. Med Hypotheses 1992;39: 342-348.
2. Chainani-Wu N: Safety and anti-inflammatory activity of curcumin: A component of turmeric (Curcuma longa). J Altern Complement Med 2003;9:161-168.
3. Dugenci SK, Arda N, Candan A: Some medicinal plants as immunostimulant for fish. J Ethnopharmacol 2003;88:99-106.
4. Jagetia GC, Baliga MS, Venkatesh P, Ulloor JN: Influence of ginger rhizome (Zingiber officinale Rose) on survival, glutathione and lipid peroxidation in mice after whole-body exposure to gamma radiation. Radiat Res 2003;160:584-592.
5. Fosslien E: Biochemistry of cyclooxygenase (COX)-2 inhibitors and molecular pathology of COX-2 in neoplasia. Crit Rev Clin Lab Sci 2000;37:431-502.
6. Kuhn K, Shikhman AR, Lotz M: Role of nitric oxide, reactive oxygen species, and p38 MAP kinase in the regulation of human chondrocyte apoptosis. J Cell Physiol 2003;197:379-387.
7. Stadler J. Stefanovic-Racic M, Billiar TR, Curran RD, McIntyre LA, Georgescu HI, Simmons RL, Evans CH: Articular chondrocytes synthesize nitric oxide in response to cytokines and lipopolysaccharide. J Immunol 1991;147:3915-3920.
8. Salvemini D, Masferrer JL: Interactions of nitric oxide with cyclooxygenase: In vitro, ex vivo, and in vivo studies. Methods Enzymol 1996;269:15-25.
9. Hayashi T, Abe E, Yamate T, Taguchi Y, Jasin HE: Nitric oxide production by superficial and deep articular chondrocytes. Arthritis Rheum 1997;40:261-269.
10. Lucia T: Lifetime productivity of female swine [Ph.D. Thesis], University of Minnesota, St. Paul. 1997.
11. Paterson R, Cargill C. Pointon A: Investigations into deaths and excessive culling of sows in Australian pig herds. In: Proceedings Nordiska Jordbruksforskares Forening Seminar 265-Longevity of Sows (Danielsen V, ed.), Research Centre Foulum, Foulum, Denmark, 1996, pp. 34-45.
12. Shen CL, Hong KJ, Kim SW: Effects of ginger (Zingiber officinale Rose.) on decreasing the production of inflammatory mediators in sow osteoarthrotic cartilage explants. J Med Food 2003;6: 323-328.
13. Shen CL, Dunn DM, Henry JH, Li Y, Watkins BA: Decreased production of inflammatory mediators in human osteoarthritic chondrocytes by conjugated linoleic acids. Lipids 2004;39:161-166.
14. 15N]nitrate in biological fluids. Anal Biochem 1982;126:131-138.
15. Jovanovic DV, Mineau F, Notoya K, Reboul P, Martel-Pelletier J, Pelletier JP: Nitric oxide induced cell death in human osteoarthritic synoviocytes is mediated by tyrosine kinase activation and hydrogen peroxide and/or superoxide formation. J Rheumatol 2002;29:2165-2175.
16. Stichtenoth DO, Thoren S, Bian H, Peters-Golden M, Jakobsson PJ, Crofford LJ: Microsomal prostaglandin E synthase is regulated by proinflammatory cytokines and glucocorticoids in primary rheumatoid synovial cells. J Immunol 2001;167:469-474.
17. Chowdhury TT, Bader DL, Lee DA: Dynamic compression counteracts IL-1 beta-induced release of nitric oxide and PGE2 by superficial zone chondrocytes cultured in agarose constructs. Osteoarthritis Cartilage 2003;11:688-696.
18. Brandt KD, Smith G, Kang SY, Myers S, O'Connor B, Albrecht M: Effects of diacerein in an accelerated canine model of osteoarthritis. Osteoarthritis Cartilage 1997;5:438-439.
19. Thomson M, Al-Qattan KK, Al-Sawan SM, Alnaqeeb MA, Khan I, Ali M: The use of ginger (Zingiber officinale Rose.) as a potential anti-inflammatory and antithrombotic agent. Prostaglandins Leukot Essent Fatty Acids 2002;67:475-478.
20. Little CB, Flannery CR, Hughes CR, Mort JS, Roughley PJ, Dent C, Caterson B: Aggrecanase versus matrix metalloproteinases in the catabolism of the interglobular domain of aggrecan in vitro. Biochem J 1999;344:61-68.
21. Blot L, Marcelis A, Devogelaer J-P, Manicourt D-H: Effects of diclofenac, aceclofenac and meloxicam on the metabolism of proteoglycans and hyaluronan in osteoarthritic human cartilage. Br J Pharmacol 2000;131:1413-1421.
22. Haynes MK, Hume EL, Smith JB: Phenotypic characterization of inflammatory cells from osteoarthritic synovium and synovial fluids. Clin Immunol 2002;105:315-325.
23. Loeser RF: Chondrocyte integrin expression and function. Biorheology 2000;37:109-116.
24. Kiuchi F, Iwakami S, Shibuya M, Hanaoka F, Sankawa U: Inhibition of prostaglandin and leukotriene biosynthesis by gingerols and diarylheptanoids. Chem Pharm Bull (Tokyo) 1992;40:387-391.