Phenolic compounds isolated from Zingiber officinale roots inhibit cell adhesion

Food Chemistry

Volumn 128, Issue 3, 2011, Pages 778-782

  Lee, Seung Woong ^a   Lim, Ju Hwan ^a,b   Kim, Min Seok ^a   Jeong, Ji Hak ^a   Song, Gyu Yong ^b   Lee, Woo Song ^a   Rho, Mun Chual ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Chungnam National University   (South Korea)

Author keywords

Cell adhesion molecules; Gingerols; Shogaols; THP 1 cells; Zingiber officinale; Zingiberaceae

Indexed keywords

CELL ADHESION MOLECULES; GINGEROLS; SHOGAOLS; THP-1 CELLS; ZINGIBER OFFICINALE; ZINGIBERACEAE;

BIOMOLECULES; CELL ADHESION; CELLS; DISEASES; METHANOL; MOLECULES; PHENOLS; SPECTROSCOPIC ANALYSIS;

ADHESION;

10 GINGEROL; 10 SHOGAOL; 6 GINGEROL; 6 PARADOL; 6 SHOGAOL; 8 GINGEROL; 8 SHOGAOL; DEHYDRO 10 GINGERDIONE; DEHYDRO 6 GINGERDIONE; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; PADGEM PROTEIN; PHENOL DERIVATIVE; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ACUTE MONOCYTIC LEUKEMIA; ARTICLE; CANCER CELL; CARBON NUCLEAR MAGNETIC RESONANCE; CELL ADHESION; CELL VIABILITY; CONCENTRATION RESPONSE; DRUG ISOLATION; DRUG PROTEIN BINDING; GINGER; HUMAN; HUMAN CELL; IC 50; MASS SPECTROMETRY; PLANT ROOT; PROTON NUCLEAR MAGNETIC RESONANCE;

ZINGIBER OFFICINALE; ZINGIBERACEAE;

EID: 79955605809     PISSN: 03088146     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.foodchem.2011.03.095     Document Type: Article

References (30)

1. Afzal, M., Al-Hadidi, D., Menon, M., Pesek, M., & Dhami, M. S. I. (1992). Ginger: An ethnomedical, chemical and pharmacological review. Drug Metabolism and Drug Interactions, 18, 159-190.
2. Awang, D. V. C. (1992). Ginger. Canadian Pharmaceutical Journal, 125, 309-311.
3. Banno, K., & Mukaiyama, T. A. (1976). New synthesis of the pungent principles of ginger-zingerone, gingerol and shogaols. Bulletin of the Chemical Society of Japan, 49, 1453-1454.
4. Berlin-Rufenach, C., Otto, F., Mathies, M., Westermann, J., Owen, M. J., Hamann, A., et al. (1999). Lymphocyte migration in lymphocyte function-associated antigen (LFA)-1-deficient mice. Journal of Experimental Medicine, 189, 1467-1478. (Pubitemid 29227533)
5. Carman, C. V., Jun, C. D., Sala, A., & Springer, T. A. (2003). Endothelial cells proactively form microvilli-like membrane projections upon intercellular adhesion molecule 1 engagement of leukocyte LFA-1. Journal of Immunology, 171, 6135-6144.
6. Cotran, R. S., & Mayadas-Norton, T. (1998). Endothelial adhesion molecules in health and disease. Pathologie Biologie, 46, 164-170.
7. Eguchi, A., Murakami, A., & Ohigashi, H. (2005). Novel bioassay system for evaluating anti-oxidative activities of food items: Use of basolateral media from differentiated Caco-2 cells. Free Radical Research, 39, 1367-1375. (Pubitemid 43023802)
8. Gabriele, W. S., Karl, W., Volker, B., Tetsji, K., Joerg, K., Christian, B., et al. (2001). Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site. Nature Medicine, 7, 687-692.
9. Gottlieb, A., Krueger, J. G., Bright, R., Ling, M., Lebwohl, M., Kang, S., et al. (2000). Effects of administration of a single dose of a humanized monoclonal antibody to CD11a on the immunobiology and clinical activity of psoriasis. Journal of the American Academy of Dermatology, 42, 428-435. (Pubitemid 30470349)
10. Gottlieb, A. B., Krueger, J. G., Wittkowski, K., Dedrick, R., Walicke, P. A., & Garovoy, M. (2002). Psoriasis as a model for T-cell-mediated disease: Immunobiologic and clinical effects of treatment with multiple doses of efalizumab, an anti-CD11a monoclonal antibody. Archives of Dermatology, 138, 591-600.
11. Harlan, J. M., & Winn, R. K. (2002). Leukocyte-endothelial interactions: Clinical trials of anti-adhesion therapy. Critical Care Medicine, 30, S214-S219. (Pubitemid 34507993)
12. Hogg, N., Henderson, R., Leitinger, B., McDowall, A., Porter, J., & Stanley, P. (2002). Mechanisms contributing to the activity of integrins on leukocytes. Immunological Reviews, 186, 164-171.
13. Kakimoto, K., Nakamura, T., Ishii, K., Takashi, T., Iigou, H., Yagita, H., et al. (1992). The effect of anti-adhesion molecule antibody on the development of collagen-induced arthritis. Cell Immunology, 142, 326-337.
14. Kiuchi, K., Shibuya, M., & Sankawa, U. (1982). Inhibitors of prostaglandin biosynthesis from ginger. Chemical & Pharmaceutical Bulletin (Tokyo), 30, 754-757. (Pubitemid 12076282)
15. Lantz, R. C., Chen, G. J., Sarihan, M., Sólyom, A. M., Jolad, S. D., & Timmermann, B. N. (2007). The effect of extracts from ginger rhizome on inflammatory mediator production. Phytomedicine, 14, 123-128. (Pubitemid 46136942)
16. Liu, G. (2001). Small molecule antagonists of the. LFA-1/ICAM-1 interaction as potential therapeutic agents. Expert Opinion on Therapeutic Patents, 11, 1383-1393.
17. Mosmann, T. (1983). Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. Journal of Immunological Methods, 65, 55-63.
18. Pan, M. H., Hsieh, M. C., Hsu, P. C., Ho, S. Y., Lai, C. S., & Wu, H. (2008). 6-Shogaol suppressed lipopolysaccharide-induced up-expression of iNOS and COX-2 in murine macrophage. Molecular Nutrition & Food Research, 52, 1467-1477.
19. Sharma, S. S., Kochupillai, V., Gupta, S. K., Seth, S. D., & Gupta, Y. K. (1997). Antiemetic efficacy of ginger (Zingiber officinale) against cisplatin-induced emesis in dogs. Journal of Ethnopharmacology, 57, 93-96. (Pubitemid 27344800)
20. Shimaoka, M., & Springer, T. A. (2004). Therapeutic antagonists and the conformational regulation of the beta2 integrins. Current Topics in Medicinal Chemistry, 4, 1485-1495.
21. Shoji, N., Iwasa, A., Takemoto, T., Ishida, Y., & Ohizumi, Y. (1982). Cardiotonic principles of ginger (Zingiber officinale Roscoe). Journal of Pharmaceutical Sciences, 71, 1174-1175. (Pubitemid 12032690)
22. Springer, T. A. (1990). Adhesion receptors of the immune system. Nature, 346, 425-434.
23. Springer, T. A. (1994). Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm. Cell, 76, 301-314.
24. Staunton, D. E., Marlin, S. D., Stratowa, C., Dustin, M. L., & Springer, T. A. (1988). Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families. Cell, 52, 925-933.
25. Surh, Y. J. (2002). Anti-tumor promoting potential of selected spice ingredients with antioxidative and anti-inflammatory activities: A short review. Food and Chemical Toxicology, 40, 1091-1097.
26. Tapsell, L. C., Hemphill, I., Cobiac, L., Patch, C. S., Sullivan, D. R., Fenech, M., et al. (2006). Health benefits of herbs and spices: The past, the present, the future. The Medical Journal of Australia, 185, S4-S24.
27. Tripathi, S., Maier, K. G., Brush, D., & Kittur, D. S. (2007). Effect of 6-gingerol on proinflammatory cytokine production and costimulatory molecule expression in murine peritoneal macrophages. Journal of Surgical Research, 138, 209-213. (Pubitemid 46365725)
28. Von Andrian, U. H., & Mackay, C. R. (2000). T-cell function and migration-two sides of the same coin. The New England Journal of Medicine, 343, 1020-1034.
29. Wang, W. H., & Wang, Z. M. (2005). Studies of commonly used traditional medicine-ginger. Zhongguo Zhong Yao Za Zhi, 30, 1569-1573.
30. Woska, J. R., Shih, D.-T., Taqueti, V. R., Hogg, N., Kelly, T. A., & Kishimoto, T. K. (2001). A small-molecule antagonist of LFA-1 blocks a conformational change important for LFA-1 function. Journal of Leukocyte Biology, 70, 329-334. (Pubitemid 32751526)