TBK1-targeted suppression of TRIF-dependent signaling pathway of toll-like receptors by 6-shogaol, an active component of ginger

Bioscience, Biotechnology and Biochemistry

Volumn 73, Issue 7, 2009, Pages 1474-1478

  Park, Se Jeong ^a   Lee, Mi Young ^a   Son, Bu Soon ^a   Youn, Hyung Sun ^a  

^a Soonchunhyang University   (South Korea)

Author keywords

6 shoagol; Lipopolysaccharide; TANK binding kinase1; Toll interleukin 1 (IL 1) receptor domain containing adapter inducing interferon ; Toll like receptors

Indexed keywords

6-SHOAGOL; ACTIVE COMPONENTS; ACTIVE INGREDIENTS; DIFFERENTIAL FACTORS; IN-VITRO; INNATE IMMUNE RESPONSE; KINASE ACTIVITY; LIPOPOLYSACCHARIDE; LIPOPOLYSACCHARIDES; MICROBIAL COMPONENTS; MICROBIAL INFECTIONS; MOLECULAR TARGETS; NUCLEAR FACTOR-KB; OVER-EXPRESSION; PRIMARY SENSORS; RECEPTOR DOMAINS; REGULATORY FACTORS; SIGNALING PATHWAYS; TANK-BINDING KINASE1; TARGET GENE EXPRESSION; TOLL-LIKE RECEPTORS;

ANTIBIOTICS; FOOD ADDITIVES; GENE EXPRESSION; GLYCOPROTEINS; INTERFERONS; PIGMENTS; POLYSACCHARIDES; TANKS (CONTAINERS);

SIGNALING;

CATECHOL DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN SERINE THREONINE KINASE; SHOGAOL; TOLL LIKE RECEPTOR; VESICULAR TRANSPORT ADAPTOR PROTEIN;

ANIMAL; ARTICLE; CATTLE; CELL LINE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; GINGER; HUMAN; METABOLISM; MOUSE; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; CATECHOLS; CATTLE; CELL LINE; ENZYME ACTIVATION; GINGER; HUMANS; MICE; NF-KAPPA B; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS;

ZINGIBER OFFICINALE;

EID: 68649096651     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.80738     Document Type: Article

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