메뉴 건너뛰기




Volumn 137, Issue 2, 2014, Pages 469-477

Photosafety screening of phenothiazine derivatives with combined use of photochemical and cassette-dosing pharmacokinetic data

Author keywords

Phenothiazines; Photoreactivity; Photosafety assessment; Phototoxicity; Reactive oxygen species

Indexed keywords

CHLORPROMAZINE; DRUG METABOLITE; FLUPHENAZINE; MEQUITAZINE; PERPHENAZINE; PHENOTHIAZINE DERIVATIVE; PROCHLORPERAZINE MALEATE; PROMETHAZINE; REACTIVE OXYGEN METABOLITE; THIORIDAZINE; TRIFLUOPERAZINE;

EID: 84893394574     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kft260     Document Type: Article
Times cited : (15)

References (30)
  • 1
    • 33845580312 scopus 로고    scopus 로고
    • Blood or plasma to skin distribution of drugs: A linear free energy analysis
    • Abraham, M. H., and Ibrahim, A. (2007). Blood or plasma to skin distribution of drugs: A linear free energy analysis. Int. J. Pharm. 329, 129-134.
    • (2007) Int. J. Pharm. , vol.329 , pp. 129-134
    • Abraham, M.H.1    Ibrahim, A.2
  • 2
    • 0022272161 scopus 로고
    • Photoinduced free radicals from chlorpromazine and related phenothiazines: Relationship to phenothiazine-induced photosensitization
    • Chignell, C. F., Motten, A. G., and Buettner, G. R. (1985). Photoinduced free radicals from chlorpromazine and related phenothiazines: Relationship to phenothiazine-induced photosensitization. Environ. Health Perspect. 64, 103-110.
    • (1985) Environ. Health Perspect. , vol.64 , pp. 103-110
    • Chignell, C.F.1    Motten, A.G.2    Buettner, G.R.3
  • 3
    • 0017796735 scopus 로고
    • Personnel radiation dosimetry in drug photosensitivity: Field study of patients on phenothiazine therapy
    • Corbett, M. F., Davis, A., and Magnus, I. A. (1978). Personnel radiation dosimetry in drug photosensitivity: Field study of patients on phenothiazine therapy. Br. J. Dermatol. 98, 39-46.
    • (1978) Br. J. Dermatol. , vol.98 , pp. 39-46
    • Corbett, M.F.1    Davis, A.2    Magnus, I.A.3
  • 4
    • 1842373293 scopus 로고    scopus 로고
    • Phototoxic properties of neuroleptic drugs
    • Eberlein-König, B., Bindl, A., and Przybilla, B. (1997). Phototoxic properties of neuroleptic drugs. Dermatology 194, 131-135.
    • (1997) Dermatology , vol.194 , pp. 131-135
    • Eberlein-König, B.1    Bindl, A.2    Przybilla, B.3
  • 8
    • 67349230303 scopus 로고    scopus 로고
    • Can light absorption and photostability data be used to assess the photosafety risks in patients for a new drug molecule?
    • Henry, B., Foti, C., and Alsante, K. (2009). Can light absorption and photostability data be used to assess the photosafety risks in patients for a new drug molecule? J. Photochem. Photobiol. B. 96, 57-62.
    • (2009) J. Photochem. Photobiol. B. , vol.96 , pp. 57-62
    • Henry, B.1    Foti, C.2    Alsante, K.3
  • 10
    • 0017639719 scopus 로고
    • Phenothiazine phototoxicity: An experimental study on chlorpromazine and its metabolites
    • Ljunggren, B., and Möller, H. (1977). Phenothiazine phototoxicity: An experimental study on chlorpromazine and its metabolites. J. Invest. Dermatol. 68, 313-317.
    • (1977) J. Invest. Dermatol. , vol.68 , pp. 313-317
    • Ljunggren, B.1    Möller, H.2
  • 11
    • 3242778456 scopus 로고    scopus 로고
    • Whatever happened to cassette-dosing pharmacokinetics?
    • Manitpisitkul, P., and White, R. E. (2004). Whatever happened to cassette-dosing pharmacokinetics? Drug Discov. Today 9, 652-658.
    • (2004) Drug Discov. Today , vol.9 , pp. 652-658
    • Manitpisitkul, P.1    White, R.E.2
  • 12
    • 31844454908 scopus 로고    scopus 로고
    • In vitro phototoxicity of phenothiazines: Involvement of stable UVA photolysis products formed in aqueous medium
    • Miolo, G., Levorato, L., Gallocchio, F., Caffieri, S., Bastianon, C., Zanoni, R., and Reddi, E. (2006). In vitro phototoxicity of phenothiazines: Involvement of stable UVA photolysis products formed in aqueous medium. Chem. Res. Toxicol. 19, 156-163.
    • (2006) Chem. Res. Toxicol. , vol.19 , pp. 156-163
    • Miolo, G.1    Levorato, L.2    Gallocchio, F.3    Caffieri, S.4    Bastianon, C.5    Zanoni, R.6    Reddi, E.7
  • 13
    • 0032501126 scopus 로고    scopus 로고
    • Mechanisms of photosensitization by phototoxic drugs
    • Moore, D. E. (1998). Mechanisms of photosensitization by phototoxic drugs. Mutat. Res. 422, 165-173.
    • (1998) Mutat. Res. , vol.422 , pp. 165-173
    • Moore, D.E.1
  • 14
    • 0036279441 scopus 로고    scopus 로고
    • Drug-induced cutaneous photosensitivity: Incidence, mechanism, prevention and management
    • Moore, D. E. (2002). Drug-induced cutaneous photosensitivity: Incidence, mechanism, prevention and management. Drug Saf. 25, 345-372.
    • (2002) Drug Saf. , vol.25 , pp. 345-372
    • Moore, D.E.1
  • 15
    • 0027250867 scopus 로고
    • Pharmacological studies on cutaneous inflammation induced by ultraviolet irradiation (1): Quantification of erythema by reflectance colorimetry and correlation with cutaneous blood flow
    • Nose, T., and Tsurumi, K. (1993). Pharmacological studies on cutaneous inflammation induced by ultraviolet irradiation (1): Quantification of erythema by reflectance colorimetry and correlation with cutaneous blood flow. Jpn. J. Pharmacol. 62, 245-256.
    • (1993) Jpn. J. Pharmacol. , vol.62 , pp. 245-256
    • Nose, T.1    Tsurumi, K.2
  • 16
    • 25644432500 scopus 로고    scopus 로고
    • OECD, In Vitro 3T3 NRU Phototoxicity Test
    • OECD (2004). OECD Guideline for Testing of Chemicals, 432, In Vitro 3T3 NRU Phototoxicity Test.
    • (2004) OECD Guideline for Testing of Chemicals , vol.432
  • 17
    • 84884700623 scopus 로고    scopus 로고
    • Establishment and intra-/inter-laboratory validation of a standard protocol of reactive oxygen species assay for chemical photosafety evaluation
    • Onoue, S., Hosoi, K., Wakuri, S., Iwase, Y., Yamamoto, T., Matsuoka, N., Nakamura, K., Toda, T., Takagi, H., Osaki, N., et al. (2013). Establishment and intra-/inter-laboratory validation of a standard protocol of reactive oxygen species assay for chemical photosafety evaluation. J. Appl. Toxicol. 33, 1241-1250.
    • (2013) J. Appl. Toxicol. , vol.33 , pp. 1241-1250
    • Onoue, S.1    Hosoi, K.2    Wakuri, S.3    Iwase, Y.4    Yamamoto, T.5    Matsuoka, N.6    Nakamura, K.7    Toda, T.8    Takagi, H.9    Osaki, N.10
  • 18
    • 36849044183 scopus 로고    scopus 로고
    • High-throughput reactive oxygen species (ROS) assay: An enabling technology for screening the phototoxic potential of pharmaceutical substances
    • Onoue, S., Igarashi, N., Yamada, S., and Tsuda, Y. (2008a). High-throughput reactive oxygen species (ROS) assay: An enabling technology for screening the phototoxic potential of pharmaceutical substances. J. Pharm. Biomed. Anal. 46, 187-193.
    • (2008) J. Pharm. Biomed. Anal. , vol.46 , pp. 187-193
    • Onoue, S.1    Igarashi, N.2    Yamada, S.3    Tsuda, Y.4
  • 19
    • 46549087839 scopus 로고    scopus 로고
    • Reactive oxygen species assaybased risk assessment of drug-induced phototoxicity: Classification criteria and application to drug candidates
    • Onoue, S., Kawamura, K., Igarashi, N., Zhou, Y., Fujikawa, M., Yamada, H., Tsuda, Y., Seto, Y., and Yamada, S. (2008b). Reactive oxygen species assaybased risk assessment of drug-induced phototoxicity: Classification criteria and application to drug candidates. J. Pharm. Biomed. Anal. 47, 967-972.
    • (2008) J. Pharm. Biomed. Anal. , vol.47 , pp. 967-972
    • Onoue, S.1    Kawamura, K.2    Igarashi, N.3    Zhou, Y.4    Fujikawa, M.5    Yamada, H.6    Tsuda, Y.7    Seto, Y.8    Yamada, S.9
  • 20
    • 67849108402 scopus 로고    scopus 로고
    • Drug-induced phototoxicity; an early in vitro identification of phototoxic potential of new drug entities in drug discovery and development
    • Onoue, S., Seto, Y., Gandy, G., and Yamada, S. (2009). Drug-induced phototoxicity; an early in vitro identification of phototoxic potential of new drug entities in drug discovery and development. Curr. Drug Saf. 4, 123-136.
    • (2009) Curr. Drug Saf. , vol.4 , pp. 123-136
    • Onoue, S.1    Seto, Y.2    Gandy, G.3    Yamada, S.4
  • 21
    • 32244449279 scopus 로고    scopus 로고
    • Analytical studies on the prediction of photosensitive/phototoxic potential of pharmaceutical substances
    • Onoue, S., and Tsuda, Y. (2006). Analytical studies on the prediction of photosensitive/phototoxic potential of pharmaceutical substances. Pharm. Res. 23, 156-164.
    • (2006) Pharm. Res. , vol.23 , pp. 156-164
    • Onoue, S.1    Tsuda, Y.2
  • 22
    • 0027537337 scopus 로고
    • Dihydroxyacetone test as a substitute for the dansyl chloride test
    • Piérard, G. E., and Piérard-Franchimont, C. (1993). Dihydroxyacetone test as a substitute for the dansyl chloride test. Dermatology 186, 133-137.
    • (1993) Dermatology , vol.186 , pp. 133-137
    • Piérard, G.E.1    Piérard-Franchimont, C.2
  • 24
    • 80052599856 scopus 로고    scopus 로고
    • Combined use of in vitro phototoxic assessments and cassette dosing pharmacokinetic study for phototoxicity characterization of fluoroquinolones
    • Seto, Y., Inoue, R., Ochi, M., Gandy, G., Yamada, S., and Onoue, S. (2011). Combined use of in vitro phototoxic assessments and cassette dosing pharmacokinetic study for phototoxicity characterization of fluoroquinolones. AAPS J. 13, 482-492.
    • (2011) AAPS J. , vol.13 , pp. 482-492
    • Seto, Y.1    Inoue, R.2    Ochi, M.3    Gandy, G.4    Yamada, S.5    Onoue, S.6
  • 25
    • 33847405771 scopus 로고    scopus 로고
    • The application of cassette dosing for pharmacokinetic screening in small-molecule cancer drug discovery
    • Smith, N. F., Raynaud, F. I., and Workman, P. (2007). The application of cassette dosing for pharmacokinetic screening in small-molecule cancer drug discovery. Mol. Cancer Ther. 6, 428-440.
    • (2007) Mol. Cancer Ther. , vol.6 , pp. 428-440
    • Smith, N.F.1    Raynaud, F.I.2    Workman, P.3
  • 26
    • 33646253205 scopus 로고    scopus 로고
    • Thioridazine induces immediate and delayed erythema in photopatch test
    • Takiwaki, H., Tsuchiya, K., Fujita, M., and Miyaoka, Y. (2006). Thioridazine induces immediate and delayed erythema in photopatch test. Photochem. Photobiol. 82, 523-526.
    • (2006) Photochem. Photobiol. , vol.82 , pp. 523-526
    • Takiwaki, H.1    Tsuchiya, K.2    Fujita, M.3    Miyaoka, Y.4
  • 27
    • 33748507346 scopus 로고    scopus 로고
    • Photosensitization of biomolecules by phenothiazine derivatives
    • Viola, G., and Dall'Acqua, F. (2006). Photosensitization of biomolecules by phenothiazine derivatives. Curr. Drug Targets 7, 1135-1154.
    • (2006) Curr. Drug Targets , vol.7 , pp. 1135-1154
    • Viola, G.1    Dall'Acqua, F.2
  • 28
    • 0023035888 scopus 로고
    • Quantification of UV-induced erythema with a portable computer controlled chromameter
    • Westerhof, W., van Hasselt, B. A., and Kammeijer, A. (1986). Quantification of UV-induced erythema with a portable computer controlled chromameter. Photodermatol. 3, 310-314.
    • (1986) Photodermatol. , vol.3 , pp. 310-314
    • Westerhof, W.1    van Hasselt, B.A.2    Kammeijer, A.3
  • 29
    • 0034955150 scopus 로고    scopus 로고
    • Pharmacokinetic theory of cassette dosing in drug discovery screening
    • White, R. E., and Manitpisitkul, P. (2001). Pharmacokinetic theory of cassette dosing in drug discovery screening. Drug Metab. Dispos. 29, 957-966.
    • (2001) Drug Metab. Dispos. , vol.29 , pp. 957-966
    • White, R.E.1    Manitpisitkul, P.2
  • 30
    • 77956230131 scopus 로고    scopus 로고
    • Main contribution of the cytochrome P450 isoenzyme 1A2 (CYP1A2) to N-demethylation and 5-sulfoxidation of the phenothiazine neuroleptic chlorpromazine in human liver-A comparison with other phenothiazines
    • Wójcikowski, J., Boksa, J., and Daniel, W. A. (2010). Main contribution of the cytochrome P450 isoenzyme 1A2 (CYP1A2) to N-demethylation and 5-sulfoxidation of the phenothiazine neuroleptic chlorpromazine in human liver-A comparison with other phenothiazines. Biochem. Pharmacol. 80, 1252-1259.
    • (2010) Biochem. Pharmacol. , vol.80 , pp. 1252-1259
    • Wójcikowski, J.1    Boksa, J.2    Daniel, W.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.