Blood or plasma to skin distribution of drugs: A linear free energy analysis

International Journal of Pharmaceutics

Volumn 329, Issue 1-2, 2007, Pages 129-134

  Abraham, Michael H ^a   Ibrahim, Adam ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Blood; Distribution; Hydrogen bonding; In silico; Linear free energy equation; Partition; Plasma; Rabbit; Rat; Skin; Solvation equation

Indexed keywords

2,2',4,4',5,5' HEXACHLOROBIPHENYL; ACEBUTOLOL; ACRYLIC ACID; BARBITURIC ACID DERIVATIVE; BENZENE DERIVATIVE; BETAXOLOL; BIPERIDEN; BISOPROLOL; CEFAZOLIN; DECANE; DIAZEPAM; ETHENZAMIDE; FENTANYL; GLYCYRRHETINIC ACID; HEXOBARBITAL; INAPERISONE; METOPROLOL; MIDAZOLAM; NALIDIXIC ACID; NICOTINE; OXPRENOLOL; PENTAZOCINE; PHENOBARBITAL; PINDOLOL; PROMETHAZINE; PROPRANOLOL; TERBINAFINE; TIMOLOL; UNINDEXED DRUG; VALPROIC ACID;

ANIMAL TISSUE; ARTICLE; BRAIN; CORRELATION ANALYSIS; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; MUSCLE; NONHUMAN; PRIORITY JOURNAL; RABBIT; RAT;

ANIMALS; BLOOD; DATA INTERPRETATION, STATISTICAL; HYDROGEN BONDING; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; RABBITS; RATS; SKIN; THERMODYNAMICS;

EID: 33845580312     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.08.032     Document Type: Article

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