Ursolic acid protects monocytes against metabolic stress-induced priming and dysfunction by preventing the induction of Nox4

Redox Biology

Volumn 2, Issue 1, 2014, Pages 259-266

  Ullevig, Sarah L ^a   Kim, Hong Seok ^b   Nguyen, Huynh Nga ^b   Hambright, William S ^c   Robles, Andrew J ^c   Tavakoli, Sina ^b   Asmis, Reto ^b  

^a UNIVERSITY OF TEXAS AT SAN ANTONIO   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c University of Texas Health Science Center   (United States)

Author keywords

Atherosclerosis; Monocyte; Nox4; S glutathionylation; Ursolic acid

Indexed keywords

ACTIN; GLUTAREDOXIN; GLUTAREDOXIN 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; MONOCYTE CHEMOTACTIC PROTEIN 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; THIOL; UNCLASSIFIED DRUG; URSOLIC ACID; GLUTATHIONE; NOX4 PROTEIN, HUMAN; NOX4 PROTEIN, MOUSE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TRITERPENE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHEMOTAXIS; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LEUKOCYTE ADHERENCE; MACROPHAGE MIGRATION; METABOLIC PRIMING; METABOLIC STRESS; MONOCYTE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN GLUTATHIONYLATION; PROTEIN MODIFICATION; RENAL PROTECTION; CELL PROTECTION; GLUTATHIONYLATION; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; CYTOLOGY; DIETARY SUPPLEMENT; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGICAL STRESS;

MURINAE; MUS;

ACTINS; ANIMALS; CHEMOKINE CCL2; DIETARY SUPPLEMENTS; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTAREDOXINS; GLUTATHIONE; HUMANS; MACROPHAGES, PERITONEAL; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MONOCYTES; NADPH OXIDASE; STRESS, PHYSIOLOGICAL; TRITERPENES;

EID: 84893349130     PISSN: 22132317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.redox.2014.01.003     Document Type: Article

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