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Volumn 37, Issue 2, 2014, Pages 212-216

Combination of nanoparticles with physical stimuli toward cancer therapy

Author keywords

Drug delivery system; Electroporation; Gene delivery; Hyperthermia; Sonoporation

Indexed keywords

ANTINEOPLASTIC AGENTS; DRUG DELIVERY SYSTEMS; ELECTRIC STIMULATION; HUMANS; NANOPARTICLES; NEOPLASMS; PHYSICAL STIMULATION; ULTRASONOGRAPHY;

EID: 84893281574     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b13-00703     Document Type: Review
Times cited : (18)

References (63)
  • 1
    • 4644247385 scopus 로고    scopus 로고
    • Enhanced hepatocyte-selective in vivo gene expression by stabilized galactosylated liposome/plasmid DNA complex using sodium chloride for complex formation
    • Fumoto S, Kawakami S, Ito Y, Shigeta K, Yamashita F, Hashida M. Enhanced hepatocyte-selective in vivo gene expression by stabilized galactosylated liposome/plasmid DNA complex using sodium chloride for complex formation. Mol. Ther., 10, 719-729 (2004).
    • (2004) Mol. Ther. , vol.10 , pp. 719-729
    • Fumoto, S.1    Kawakami, S.2    Ito, Y.3    Shigeta, K.4    Yamashita, F.5    Hashida, M.6
  • 3
    • 27144475378 scopus 로고    scopus 로고
    • Interaction with blood components plays a crucial role in asialoglycoprotein receptor-mediated in vivo gene transfer by galactosylated lipoplex
    • Fumoto S, Kawakami S, Shigeta K, Higuchi Y, Yamashita F, Hashida M. Interaction with blood components plays a crucial role in asialoglycoprotein receptor-mediated in vivo gene transfer by galactosylated lipoplex. J. Pharmacol. Exp. Ther., 315, 484-493 (2005).
    • (2005) J. Pharmacol. Exp. Ther. , vol.315 , pp. 484-493
    • Fumoto, S.1    Kawakami, S.2    Shigeta, K.3    Higuchi, Y.4    Yamashita, F.5    Hashida, M.6
  • 5
    • 84869496799 scopus 로고    scopus 로고
    • Macromolecular therapeutics in cancer treatment: The EPR effect and beyond
    • Maeda H. Macromolecular therapeutics in cancer treatment: the EPR effect and beyond. J. Control. Release, 164, 138-144 (2012).
    • (2012) J. Control. Release , vol.164 , pp. 138-144
    • Maeda, H.1
  • 6
    • 79953066932 scopus 로고    scopus 로고
    • A multifunctional envelope type nano device (MEND) for gene delivery to tumours based on the EPR effect: A strategy for overcoming the PEG dilemma
    • Hatakeyama H, Akita H, Harashima H. A multifunctional envelope type nano device (MEND) for gene delivery to tumours based on the EPR effect: a strategy for overcoming the PEG dilemma. Adv. Drug Deliv. Rev., 63, 152-160 (2011).
    • (2011) Adv. Drug Deliv. Rev. , vol.63 , pp. 152-160
    • Hatakeyama, H.1    Akita, H.2    Harashima, H.3
  • 7
    • 0034000572 scopus 로고    scopus 로고
    • In vivo gene delivery to the liver using novel galactosylated cationic liposomes
    • Kawakami S, Fumoto S, Nishikawa M, Yamashita F, Hashida M. In vivo gene delivery to the liver using novel galactosylated cationic liposomes. Pharm. Res., 17, 306-313 (2000).
    • (2000) Pharm. Res. , vol.17 , pp. 306-313
    • Kawakami, S.1    Fumoto, S.2    Nishikawa, M.3    Yamashita, F.4    Hashida, M.5
  • 8
    • 0141678002 scopus 로고    scopus 로고
    • Analysis of hepatic disposition of galactosylated cationic liposome/plasmid DNA complexes in perfused rat liver
    • Fumoto S, Nakadori F, Kawakami S, Nishikawa M, Yamashita F, Hashida M. Analysis of hepatic disposition of galactosylated cationic liposome/plasmid DNA complexes in perfused rat liver. Pharm. Res., 20, 1452-1459 (2003).
    • (2003) Pharm. Res. , vol.20 , pp. 1452-1459
    • Fumoto, S.1    Nakadori, F.2    Kawakami, S.3    Nishikawa, M.4    Yamashita, F.5    Hashida, M.6
  • 9
    • 33645234124 scopus 로고    scopus 로고
    • Novel PEG-matrix metalloproteinase-2 cleavable peptide-lipid containing galactosylated liposomes for hepatocellular carcinoma-selective targeting
    • Terada T, Iwai M, Kawakami S, Yamashita F, Hashida M. Novel PEG-matrix metalloproteinase-2 cleavable peptide-lipid containing galactosylated liposomes for hepatocellular carcinoma-selective targeting. J. Control. Release, 111, 333-342 (2006).
    • (2006) J. Control. Release , vol.111 , pp. 333-342
    • Terada, T.1    Iwai, M.2    Kawakami, S.3    Yamashita, F.4    Hashida, M.5
  • 11
    • 84858075524 scopus 로고    scopus 로고
    • Targeted therapy for cancer using pH-responsive nanocarrier systems
    • Manchun S, Dass CR, Sriamornsak P. Targeted therapy for cancer using pH-responsive nanocarrier systems. Life Sci., 90, 381-387 (2012).
    • (2012) Life Sci. , vol.90 , pp. 381-387
    • Manchun, S.1    Dass, C.R.2    Sriamornsak, P.3
  • 12
    • 84858241282 scopus 로고    scopus 로고
    • Direct therapeutic applications of calcium electroporation to effectively induce tumor necrosis
    • Frandsen SK, Gissel H, Hojman P, Tramm T, Eriksen J, Gehl J. Direct therapeutic applications of calcium electroporation to effectively induce tumor necrosis. Cancer Res., 72, 1336-1341 (2012).
    • (2012) Cancer Res. , vol.72 , pp. 1336-1341
    • Frandsen, S.K.1    Gissel, H.2    Hojman, P.3    Tramm, T.4    Eriksen, J.5    Gehl, J.6
  • 13
    • 84877944983 scopus 로고    scopus 로고
    • Gene transfer and drug delivery with electric pulse generators
    • Yao C, Guo F, Li C, Sun C. Gene transfer and drug delivery with electric pulse generators. Curr. Drug Metab., 14, 319-323 (2013).
    • (2013) Curr. Drug Metab. , vol.14 , pp. 319-323
    • Yao, C.1    Guo, F.2    Li, C.3    Sun, C.4
  • 20
    • 74949097184 scopus 로고    scopus 로고
    • Enhanced transfection efficiency into macrophages and dendritic cells by a combination method using mannosylated lipoplexes and bubble liposomes with ultrasound exposure
    • Un K, Kawakami S, Suzuki R, Maruyama K, Yamashita F, Hashida M. Enhanced transfection efficiency into macrophages and dendritic cells by a combination method using mannosylated lipoplexes and bubble liposomes with ultrasound exposure. Hum. Gene Ther., 21, 65-74 (2010).
    • (2010) Hum. Gene Ther. , vol.21 , pp. 65-74
    • Un, K.1    Kawakami, S.2    Suzuki, R.3    Maruyama, K.4    Yamashita, F.5    Hashida, M.6
  • 21
    • 77955772869 scopus 로고    scopus 로고
    • Development of an ultrasound-responsive and mannose-modified gene carrier for DNA vaccine therapy
    • Un K, Kawakami S, Suzuki R, Maruyama K, Yamashita F, Hashida M. Development of an ultrasound-responsive and mannose-modified gene carrier for DNA vaccine therapy. Biomaterials, 31, 7813-7826 (2010).
    • (2010) Biomaterials , vol.31 , pp. 7813-7826
    • Un, K.1    Kawakami, S.2    Suzuki, R.3    Maruyama, K.4    Yamashita, F.5    Hashida, M.6
  • 22
    • 79953809082 scopus 로고    scopus 로고
    • Suppression of melanoma growth and metastasis by DNA vaccination using an ultrasound-responsive and mannose-modified gene carrier
    • Un K, Kawakami S, Suzuki R, Maruyama K, Yamashita F, Hashida M. Suppression of melanoma growth and metastasis by DNA vaccination using an ultrasound-responsive and mannose-modified gene carrier. Mol. Pharm., 8, 543-554 (2011).
    • (2011) Mol. Pharm. , vol.8 , pp. 543-554
    • Un, K.1    Kawakami, S.2    Suzuki, R.3    Maruyama, K.4    Yamashita, F.5    Hashida, M.6
  • 23
    • 0018380868 scopus 로고
    • Hyperthermia in the treatment of cancer
    • Dickson JA. Hyperthermia in the treatment of cancer. Lancet, 313, 202-205 (1979).
    • (1979) Lancet , vol.313 , pp. 202-205
    • Dickson, J.A.1
  • 24
    • 42149128893 scopus 로고    scopus 로고
    • The role of hyperthermia in optimizing tumor response to regional therapy
    • Moyer HR, Delman KA. The role of hyperthermia in optimizing tumor response to regional therapy. Int. J. Hyperthermia, 24, 251-261 (2008).
    • (2008) Int. J. Hyperthermia , vol.24 , pp. 251-261
    • Moyer, H.R.1    Delman, K.A.2
  • 26
    • 84877938962 scopus 로고    scopus 로고
    • Mild hyperthermia triggered doxorubicin release from optimized stealth thermosensitive liposomes improves intratumoral drug delivery and efficacy
    • Li L, ten Hagen TL, Hossann M, Süss R, van Rhoon GC, Eggermont AM, Haemmerich D, Koning GA. Mild hyperthermia triggered doxorubicin release from optimized stealth thermosensitive liposomes improves intratumoral drug delivery and efficacy. J. Control. Release, 168, 142-150 (2013).
    • (2013) J. Control. Release , vol.168 , pp. 142-150
    • Li, L.1    Ten Hagen, T.L.2    Hossann, M.3    Süss, R.4    Van Rhoon, G.C.5    Eggermont, A.M.6    Haemmerich, D.7    Koning, G.A.8
  • 27
    • 33947118735 scopus 로고    scopus 로고
    • High intensity focused ultrasound: Physical principles and devices
    • Haar GT, Coussios C. High intensity focused ultrasound: physical principles and devices. Int. J. Hyperthermia, 23, 89-104 (2007).
    • (2007) Int. J. Hyperthermia , vol.23 , pp. 89-104
    • Haar, G.T.1    Coussios, C.2
  • 28
    • 84880181667 scopus 로고    scopus 로고
    • Novel temperature-triggered liposome with high stability: Formulation, in vitro evaluation, and in vivo study combined with high-intensity focused ultrasound (HIFU)
    • Park SM, Kim MS, Park SJ, Park ES, Choi KS, Kim YS, Kim HR. Novel temperature-triggered liposome with high stability: Formulation, in vitro evaluation, and in vivo study combined with high-intensity focused ultrasound (HIFU). J. Control. Release, 170, 373-379 (2013).
    • (2013) J. Control. Release , vol.170 , pp. 373-379
    • Park, S.M.1    Kim, M.S.2    Park, S.J.3    Park, E.S.4    Choi, K.S.5    Kim, Y.S.6    Kim, H.R.7
  • 29
    • 79960231793 scopus 로고    scopus 로고
    • Magnetic nanomaterials for hyperthermia-based therapy and controlled drug delivery
    • Kumar CS, Mohammad F. Magnetic nanomaterials for hyperthermia-based therapy and controlled drug delivery. Adv. Drug Deliv. Rev., 63, 789-808 (2011).
    • (2011) Adv. Drug Deliv. Rev. , vol.63 , pp. 789-808
    • Kumar, C.S.1    Mohammad, F.2
  • 31
    • 0030799914 scopus 로고    scopus 로고
    • Intratumoral delivery of boronated epidermal growth factor for neutron capture therapy of brain tumors
    • Yang W, Barth RF, Adams DM, Soloway AH. Intratumoral delivery of boronated epidermal growth factor for neutron capture therapy of brain tumors. Cancer Res., 57, 4333-4339 (1997).
    • (1997) Cancer Res. , vol.57 , pp. 4333-4339
    • Yang, W.1    Barth, R.F.2    Adams, D.M.3    Soloway, A.H.4
  • 32
    • 0036000119 scopus 로고    scopus 로고
    • Boron-containing folate receptor-targeted liposomes as potential delivery agents for neutron capture therapy
    • Pan XQ, Wang H, Shukla S, Sekido M, Adams DM, Tjarks W, Barth RF, Lee RJ. Boron-containing folate receptor-targeted liposomes as potential delivery agents for neutron capture therapy. Bioconj. Chem., 13, 435-442 (2002).
    • (2002) Bioconj. Chem. , vol.13 , pp. 435-442
    • Pan, X.Q.1    Wang, H.2    Shukla, S.3    Sekido, M.4    Adams, D.M.5    Tjarks, W.6    Barth, R.F.7    Lee, R.J.8
  • 33
    • 0036056326 scopus 로고    scopus 로고
    • Electric gene transfer to the liver following systemic administration of plasmid DNA
    • Liu F, Huang L. Electric gene transfer to the liver following systemic administration of plasmid DNA. Gene Ther., 9, 1116-1119 (2002).
    • (2002) Gene Ther. , vol.9 , pp. 1116-1119
    • Liu, F.1    Huang, L.2
  • 34
    • 21244439530 scopus 로고    scopus 로고
    • Tissue-specific characteristics of in vivo electric gene: Transfer by tissue and intravenous injection of plasmid DNA
    • Thanaketpaisarn O, Nishikawa M, Yamashita F, Hashida M. Tissue-specific characteristics of in vivo electric gene: transfer by tissue and intravenous injection of plasmid DNA. Pharm. Res., 22, 883-891 (2005).
    • (2005) Pharm. Res. , vol.22 , pp. 883-891
    • Thanaketpaisarn, O.1    Nishikawa, M.2    Yamashita, F.3    Hashida, M.4
  • 38
    • 0032805251 scopus 로고    scopus 로고
    • Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA
    • Liu F, Song Y, Liu D. Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA. Gene Ther., 6, 1258-1266 (1999).
    • (1999) Gene Ther. , vol.6 , pp. 1258-1266
    • Liu, F.1    Song, Y.2    Liu, D.3
  • 39
    • 0033166561 scopus 로고    scopus 로고
    • High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA
    • Zhang G, Budker V, Wolff JA. High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA. Hum. Gene Ther., 10, 1735-1737 (1999).
    • (1999) Hum. Gene Ther. , vol.10 , pp. 1735-1737
    • Zhang, G.1    Budker, V.2    Wolff, J.A.3
  • 40
    • 44749089187 scopus 로고    scopus 로고
    • Renal press-mediated transfection method for plasmid DNA and siRNA to the kidney
    • Mukai H, Kawakami S, Hashida M. Renal press-mediated transfection method for plasmid DNA and siRNA to the kidney. Biochem. Biophys. Res. Commun., 372, 383-387 (2008).
    • (2008) Biochem. Biophys. Res. Commun. , vol.372 , pp. 383-387
    • Mukai, H.1    Kawakami, S.2    Hashida, M.3
  • 44
    • 84863306726 scopus 로고    scopus 로고
    • Efficient in vivo gene transfer by intraperitoneal injection of plasmid DNA and calcium carbonate microflowers in mice
    • Fumoto S, Nakajima S, Mine T, Yoshikawa N, Kitahara T, Sasaki H, Miyamoto H, Nishida K. Efficient in vivo gene transfer by intraperitoneal injection of plasmid DNA and calcium carbonate microflowers in mice. Mol. Pharm., 9, 1962-1970 (2012).
    • (2012) Mol. Pharm. , vol.9 , pp. 1962-1970
    • Fumoto, S.1    Nakajima, S.2    Mine, T.3    Yoshikawa, N.4    Kitahara, T.5    Sasaki, H.6    Miyamoto, H.7    Nishida, K.8
  • 45
    • 0032478744 scopus 로고    scopus 로고
    • Direct gene transfer into rat liver cells by in vivo electroporation
    • Suzuki T, Shin BC, Fujikura K, Matsuzaki T, Takata K. Direct gene transfer into rat liver cells by in vivo electroporation. FEBS Lett., 425, 436-440 (1998).
    • (1998) FEBS Lett. , vol.425 , pp. 436-440
    • Suzuki, T.1    Shin, B.C.2    Fujikura, K.3    Matsuzaki, T.4    Takata, K.5
  • 46
    • 84859482744 scopus 로고    scopus 로고
    • Implantable pneumatically actuated microsystem for renal pressure-mediated transfection in mice
    • Shimizu K, Kawakami S, Hayashi K, Mori Y, Hashida M, Konishi S. Implantable pneumatically actuated microsystem for renal pressure-mediated transfection in mice. J. Control. Release, 159, 85-91 (2012).
    • (2012) J. Control. Release , vol.159 , pp. 85-91
    • Shimizu, K.1    Kawakami, S.2    Hayashi, K.3    Mori, Y.4    Hashida, M.5    Konishi, S.6
  • 47
    • 79955524005 scopus 로고    scopus 로고
    • The elucidation of gene transferring mechanism by ultrasound-responsive unmodified and mannose-modified lipoplexes
    • Un K, Kawakami S, Yoshida M, Higuchi Y, Suzuki R, Maruyama K, Yamashita F, Hashida M. The elucidation of gene transferring mechanism by ultrasound-responsive unmodified and mannose-modified lipoplexes. Biomaterials, 32, 4659-4669 (2011).
    • (2011) Biomaterials , vol.32 , pp. 4659-4669
    • Un, K.1    Kawakami, S.2    Yoshida, M.3    Higuchi, Y.4    Suzuki, R.5    Maruyama, K.6    Yamashita, F.7    Hashida, M.8
  • 49
    • 54949100776 scopus 로고    scopus 로고
    • Reactivation of silenced transgene expression in mouse liver by rapid, large-volume injection of isotonic solution
    • Nishikawa M, Nakayama A, Takahashi Y, Fukuhara Y, Takakura Y. Reactivation of silenced transgene expression in mouse liver by rapid, large-volume injection of isotonic solution. Hum. Gene Ther., 19, 1009-1020 (2008).
    • (2008) Hum. Gene Ther. , vol.19 , pp. 1009-1020
    • Nishikawa, M.1    Nakayama, A.2    Takahashi, Y.3    Fukuhara, Y.4    Takakura, Y.5
  • 50
    • 79955579208 scopus 로고    scopus 로고
    • Positive correlation between the generation of reactive oxygen species and activation/reactivation of transgene expression after hydrodynamic injections into mice
    • Takiguchi N, Takahashi Y, Nishikawa M, Matsui Y, Fukuhara Y, Oushiki D, Kiyose K, Hanaoka K, Nagano T, Takakura Y. Positive correlation between the generation of reactive oxygen species and activation/reactivation of transgene expression after hydrodynamic injections into mice. Pharm. Res., 28, 702-711 (2011).
    • (2011) Pharm. Res. , vol.28 , pp. 702-711
    • Takiguchi, N.1    Takahashi, Y.2    Nishikawa, M.3    Matsui, Y.4    Fukuhara, Y.5    Oushiki, D.6    Kiyose, K.7    Hanaoka, K.8    Nagano, T.9    Takakura, Y.10
  • 51
    • 82755189369 scopus 로고    scopus 로고
    • Involvement of activated transcriptional process in efficient gene transfection using unmodified and mannose-modified bubble lipoplexes with ultrasound exposure
    • Un K, Kawakami S, Higuchi Y, Suzuki R, Maruyama K, Yamashita F, Hashida M. Involvement of activated transcriptional process in efficient gene transfection using unmodified and mannose-modified bubble lipoplexes with ultrasound exposure. J. Control. Release, 156, 355-363 (2011).
    • (2011) J. Control. Release , vol.156 , pp. 355-363
    • Un, K.1    Kawakami, S.2    Higuchi, Y.3    Suzuki, R.4    Maruyama, K.5    Yamashita, F.6    Hashida, M.7
  • 52
    • 77957586831 scopus 로고    scopus 로고
    • Key physiological phenomena governing transgene expression based on tissue pressure-mediated transfection in mice
    • Mukai H, Kawakami S, Takahashi H, Satake K, Yamashita F, Hashida M. Key physiological phenomena governing transgene expression based on tissue pressure-mediated transfection in mice. Biol. Pharm. Bull., 33, 1627-1632 (2010).
    • (2010) Biol. Pharm. Bull. , vol.33 , pp. 1627-1632
    • Mukai, H.1    Kawakami, S.2    Takahashi, H.3    Satake, K.4    Yamashita, F.5    Hashida, M.6
  • 55
    • 33749428993 scopus 로고    scopus 로고
    • Stomach-selective gene transfer following the administration of naked plasmid DNA onto the gastric serosal surface in mice
    • Nakamura J, Fumoto S, Shoji K, Kodama Y, Nishi J, Nakashima M, Sasaki H, Nishida K. Stomach-selective gene transfer following the administration of naked plasmid DNA onto the gastric serosal surface in mice. Biol. Pharm. Bull., 29, 2082-2086 (2006).
    • (2006) Biol. Pharm. Bull. , vol.29 , pp. 2082-2086
    • Nakamura, J.1    Fumoto, S.2    Shoji, K.3    Kodama, Y.4    Nishi, J.5    Nakashima, M.6    Sasaki, H.7    Nishida, K.8
  • 56
    • 43249129908 scopus 로고    scopus 로고
    • Improved stomach selectivity of gene expression following microinstillation of plasmid DNA onto the gastric serosal surface in mice
    • Nishi J, Fumoto S, Ishii H, Kodama Y, Nakashima M, Sasaki H, Nakamura J, Nishida K. Improved stomach selectivity of gene expression following microinstillation of plasmid DNA onto the gastric serosal surface in mice. Eur. J. Pharm. Biopharm., 69, 633-639 (2008).
    • (2008) Eur. J. Pharm. Biopharm. , vol.69 , pp. 633-639
    • Nishi, J.1    Fumoto, S.2    Ishii, H.3    Kodama, Y.4    Nakashima, M.5    Sasaki, H.6    Nakamura, J.7    Nishida, K.8
  • 58
    • 84893297840 scopus 로고    scopus 로고
    • Targeted Gene Delivery: Importance of Administration Routes
    • Wei M, Good D eds. Intech, Croatia
    • Fumoto S, Kawakami S, Hashida M, Nishida K. Targeted Gene Delivery: Importance of Administration Routes. NOVEL GENE THERAPY APPROACHES (Wei M, Good D eds.) Intech, Croatia, pp. 3-31 (2013).
    • (2013) NOVEL GENE THERAPY APPROACHES , pp. 3-31
    • Fumoto, S.1    Kawakami, S.2    Hashida, M.3    Nishida, K.4
  • 60
    • 16344370911 scopus 로고    scopus 로고
    • Hepatocyte-targeted gene transfer by combination of vascularly delivered plasmid DNA and in vivo electroporation
    • Sakai M, Nishikawa M, Thanaketpaisarn O, Yamashita F, Hashida M. Hepatocyte-targeted gene transfer by combination of vascularly delivered plasmid DNA and in vivo electroporation. Gene Ther., 12, 607-616 (2005).
    • (2005) Gene Ther. , vol.12 , pp. 607-616
    • Sakai, M.1    Nishikawa, M.2    Thanaketpaisarn, O.3    Yamashita, F.4    Hashida, M.5
  • 61
    • 17944369209 scopus 로고    scopus 로고
    • In vivo electroporation-mediated transfer of interleukin-12 and interleukin-18 genes induces significant antitumor effects against melanoma in mice
    • Kishida T, Asada H, Satoh E, Tanaka S, Shinya M, Hirai H, Iwai M, Tahara H, Imanishi J, Mazda O. In vivo electroporation-mediated transfer of interleukin-12 and interleukin-18 genes induces significant antitumor effects against melanoma in mice. Gene Ther., 8, 1234-1240 (2001).
    • (2001) Gene Ther. , vol.8 , pp. 1234-1240
    • Kishida, T.1    Asada, H.2    Satoh, E.3    Tanaka, S.4    Shinya, M.5    Hirai, H.6    Iwai, M.7    Tahara, H.8    Imanishi, J.9    Mazda, O.10
  • 62
    • 0034063693 scopus 로고    scopus 로고
    • Electroporation-enhanced gene delivery in mammary tumors
    • Wells JM, Li LH, Sen A, Jahreis GP, Hui SW. Electroporation-enhanced gene delivery in mammary tumors. Gene Ther., 7, 541-547 (2000).
    • (2000) Gene Ther. , vol.7 , pp. 541-547
    • Wells, J.M.1    Li, L.H.2    Sen, A.3    Jahreis, G.P.4    Hui, S.W.5
  • 63
    • 84863531145 scopus 로고    scopus 로고
    • Efficient suppression of murine intracellular adhesion molecule-1 using ultrasound-responsive and mannose-modified lipoplexes inhibits acute hepatic inflammation
    • Un K, Kawakami S, Yoshida M, Higuchi Y, Suzuki R, Maruyama K, Yamashita F, Hashida M. Efficient suppression of murine intracellular adhesion molecule-1 using ultrasound-responsive and mannose-modified lipoplexes inhibits acute hepatic inflammation. Hepatology, 56, 259-269 (2012).
    • (2012) Hepatology , vol.56 , pp. 259-269
    • Un, K.1    Kawakami, S.2    Yoshida, M.3    Higuchi, Y.4    Suzuki, R.5    Maruyama, K.6    Yamashita, F.7    Hashida, M.8


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