Analysis of hepatic disposition of galactosylated cationic liposome/ plasmid DNA complexes in perfused rat liver

Pharmaceutical Research

Volumn 20, Issue 9, 2003, Pages 1452-1459

  Fumoto, Shintaro ^a   Nakadori, Fumi ^a   Kawakami, Shigeru ^a   Nishikawa, Makiya ^a   Yamashita, Fumiyoshi ^a   Hashida, Mitsuru ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Cationic liposomes; Dispersion model; Galactosylated liposomes; Gene delivery

Indexed keywords

AMMONIUM DERIVATIVE; CHOLESTEN 5 YLOXY N [4 [(1 IMINO 2 DEXTRO THIOGALACTOSYLETHYL)AMINO]BUTYL]FORMAMIDE; CHOLESTEROL; FORMAMIDE DERIVATIVE; GALACTOSE; LIPOSOME; N [1 (2,3 DIOLEYLOXY)PROPYL] N,N,N TRIMETHYLAMMONIUM CHLORIDE; PHOSPHORUS 32; PLASMID DNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CELL MEMBRANE PERMEABILITY; CELLULAR DISTRIBUTION; COMPARTMENT MODEL; COMPLEX FORMATION; CONTROLLED STUDY; DISPERSION; DNA EXTRACTION; DRUG DISPOSITION; DRUG LABELING; DRUG UPTAKE; LIVER PERFUSION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TISSUE DISTRIBUTION; VEIN BLOOD FLOW;

ANIMALS; CATIONS; CHOLESTEROL; DNA; GALACTOSE; GENE TRANSFER TECHNIQUES; LIPOSOMES; MALE; MICROSOMES, LIVER; MODELS, BIOLOGICAL; PERFUSION; PLASMIDS; QUATERNARY AMMONIUM COMPOUNDS; RATS; RATS, WISTAR; TIME FACTORS;

EID: 0141678002     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1025766429175     Document Type: Article

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