-
1
-
-
0025808629
-
Coexpression of two distinct genes is required to generate secreted bioactive cytotoxic lymphocyte maturation factor
-
Gubler U., Chua A.O., Schoenhaut D.S., Dwyer C.M., McComas W., Motyka R., Nabavi N., Wolitzky A.G., Quinn P.M., Familletti P.C. Coexpression of two distinct genes is required to generate secreted bioactive cytotoxic lymphocyte maturation factor. Proc Natl Acad Sci U S A 1991, 88:4143-4147.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 4143-4147
-
-
Gubler, U.1
Chua, A.O.2
Schoenhaut, D.S.3
Dwyer, C.M.4
McComas, W.5
Motyka, R.6
Nabavi, N.7
Wolitzky, A.G.8
Quinn, P.M.9
Familletti, P.C.10
-
2
-
-
0025875022
-
Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells
-
Wolf S.F., Temple P.A., Kobayashi M., Young D., Dicig M., Lowe L., Dzialo R., Fitz L., Ferenz C., Hewick R.M. Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells. J Immunol 1991, 146:3074-3081.
-
(1991)
J Immunol
, vol.146
, pp. 3074-3081
-
-
Wolf, S.F.1
Temple, P.A.2
Kobayashi, M.3
Young, D.4
Dicig, M.5
Lowe, L.6
Dzialo, R.7
Fitz, L.8
Ferenz, C.9
Hewick, R.M.10
-
3
-
-
0028012527
-
Interleukin-12
-
Brunda M.J. Interleukin-12. J Leukoc Biol 1994, 55:280-288.
-
(1994)
J Leukoc Biol
, vol.55
, pp. 280-288
-
-
Brunda, M.J.1
-
4
-
-
0027963161
-
Recombinant IL-12 administration induces tumor regression in association with IFN-gamma production
-
Nastala C.L., Edington H.D., McKinney T.G., Tahara H., Nalesnik M.A., Brunda M.J., Gately M.K., Wolf S.F., Schreiber R.D., Storkus W.J. Recombinant IL-12 administration induces tumor regression in association with IFN-gamma production. J Immunol 1994, 153:1697-1706.
-
(1994)
J Immunol
, vol.153
, pp. 1697-1706
-
-
Nastala, C.L.1
Edington, H.D.2
McKinney, T.G.3
Tahara, H.4
Nalesnik, M.A.5
Brunda, M.J.6
Gately, M.K.7
Wolf, S.F.8
Schreiber, R.D.9
Storkus, W.J.10
-
5
-
-
0030727981
-
IL-12-induced tumor regression correlates with in situ activity of IFN-gamma produced by tumor-infiltrating cells and its secondary induction of anti-tumor pathways
-
Yu W.G., Ogawa M., Mu J., Umehara K., Tsujimura T., Fujiwara H., Hamaoka T. IL-12-induced tumor regression correlates with in situ activity of IFN-gamma produced by tumor-infiltrating cells and its secondary induction of anti-tumor pathways. J Leukoc Biol 1997, 62:450-457.
-
(1997)
J Leukoc Biol
, vol.62
, pp. 450-457
-
-
Yu, W.G.1
Ogawa, M.2
Mu, J.3
Umehara, K.4
Tsujimura, T.5
Fujiwara, H.6
Hamaoka, T.7
-
6
-
-
0030887047
-
Phase I evaluation of intravenous recombinant human interleukin 12 in patients with advanced malignancies
-
Atkins M.B., Robertson M.J., Gordon M., Lotze M.T., DeCoste M., DuBois J.S., Ritz J., Sandler A.B., Edington H.D., Garzone P.D., Mier J.W., Canning C.M., Battiato L., Tahara H., Sherman M.L. Phase I evaluation of intravenous recombinant human interleukin 12 in patients with advanced malignancies. Clin Cancer Res 1997, 3:409-417.
-
(1997)
Clin Cancer Res
, vol.3
, pp. 409-417
-
-
Atkins, M.B.1
Robertson, M.J.2
Gordon, M.3
Lotze, M.T.4
DeCoste, M.5
DuBois, J.S.6
Ritz, J.7
Sandler, A.B.8
Edington, H.D.9
Garzone, P.D.10
Mier, J.W.11
Canning, C.M.12
Battiato, L.13
Tahara, H.14
Sherman, M.L.15
-
7
-
-
0030766971
-
Effects of single-dose interleukin-12 exposure on interleukin-12-associated toxicity and interferon-gamma production
-
Leonard J.P., Sherman M.L., Fisher G.L., Buchanan L.J., Larsen G., Atkins M.B., Sosman J.A., Dutcher J.P., Vogelzang N.J., Ryan J.L. Effects of single-dose interleukin-12 exposure on interleukin-12-associated toxicity and interferon-gamma production. Blood 1997, 90:2541-2548.
-
(1997)
Blood
, vol.90
, pp. 2541-2548
-
-
Leonard, J.P.1
Sherman, M.L.2
Fisher, G.L.3
Buchanan, L.J.4
Larsen, G.5
Atkins, M.B.6
Sosman, J.A.7
Dutcher, J.P.8
Vogelzang, N.J.9
Ryan, J.L.10
-
8
-
-
0029898839
-
Amount of interleukin 12 available at the tumor site is critical for tumor regression
-
Colombo M.P., Vagliani M., Spreafico F., Parenza M., Chiodoni C., Melani C., Stoppacciaro A. Amount of interleukin 12 available at the tumor site is critical for tumor regression. Cancer Res 1996, 56:2531-2534.
-
(1996)
Cancer Res
, vol.56
, pp. 2531-2534
-
-
Colombo, M.P.1
Vagliani, M.2
Spreafico, F.3
Parenza, M.4
Chiodoni, C.5
Melani, C.6
Stoppacciaro, A.7
-
9
-
-
13744259801
-
A single intratumoral injection of a fiber-mutant adenoviral vector encoding interleukin 12 induces remarkable anti-tumor and anti-metastatic activity in mice with Meth-A fibrosarcoma
-
Gao J.Q., Sugita T., Kanagawa N., Iida K., Eto Y., Motomura Y., Mizuguchi H., Tsutsumi Y., Hayakawa T., Mayumi T., Nakagawa S. A single intratumoral injection of a fiber-mutant adenoviral vector encoding interleukin 12 induces remarkable anti-tumor and anti-metastatic activity in mice with Meth-A fibrosarcoma. Biochem Biophys Res Commun 2005, 328:1043-1050.
-
(2005)
Biochem Biophys Res Commun
, vol.328
, pp. 1043-1050
-
-
Gao, J.Q.1
Sugita, T.2
Kanagawa, N.3
Iida, K.4
Eto, Y.5
Motomura, Y.6
Mizuguchi, H.7
Tsutsumi, Y.8
Hayakawa, T.9
Mayumi, T.10
Nakagawa, S.11
-
10
-
-
44749083254
-
Arginine-chitosan/DNA self-assemble nanoparticles for gene delivery: in vitro characteristics and transfection efficiency
-
Gao Y., Xu Z., Chen S., Gu W., Chen L., Li Y. Arginine-chitosan/DNA self-assemble nanoparticles for gene delivery: in vitro characteristics and transfection efficiency. Int J Pharm 2008, 359:241-246.
-
(2008)
Int J Pharm
, vol.359
, pp. 241-246
-
-
Gao, Y.1
Xu, Z.2
Chen, S.3
Gu, W.4
Chen, L.5
Li, Y.6
-
11
-
-
33845625261
-
Development of a novel systemic gene delivery system for cancer therapy with a tumor-specific cleavable PEG-lipid
-
Hatakeyama H., Akita H., Kogure K., Oishi M., Nagasaki Y., Kihira Y., Ueno M., Kobayashi H., Kikuchi H., Harashima H. Development of a novel systemic gene delivery system for cancer therapy with a tumor-specific cleavable PEG-lipid. Gene Ther 2007, 14:68-77.
-
(2007)
Gene Ther
, vol.14
, pp. 68-77
-
-
Hatakeyama, H.1
Akita, H.2
Kogure, K.3
Oishi, M.4
Nagasaki, Y.5
Kihira, Y.6
Ueno, M.7
Kobayashi, H.8
Kikuchi, H.9
Harashima, H.10
-
12
-
-
59249085987
-
Progress in cationic lipid-mediated gene transfection: a series of bio-inspired lipids as an example
-
Montier T., Benvegnu T., Jaffres P.A., Yaouanc J.J., Lehn P. Progress in cationic lipid-mediated gene transfection: a series of bio-inspired lipids as an example. Curr Gene Ther 2008, 8:296-312.
-
(2008)
Curr Gene Ther
, vol.8
, pp. 296-312
-
-
Montier, T.1
Benvegnu, T.2
Jaffres, P.A.3
Yaouanc, J.J.4
Lehn, P.5
-
13
-
-
46549090126
-
Progress in developing cationic vectors for non-viral systemic gene therapy against cancer
-
Morille M., Passirani C., Vonarbourg A., Clavreul A., Benoit J.P. Progress in developing cationic vectors for non-viral systemic gene therapy against cancer. Biomaterials 2008, 29:3477-3496.
-
(2008)
Biomaterials
, vol.29
, pp. 3477-3496
-
-
Morille, M.1
Passirani, C.2
Vonarbourg, A.3
Clavreul, A.4
Benoit, J.P.5
-
14
-
-
0023463013
-
Transfection of mammalian cells with plasmid DNA by scrape loading and sonication loading
-
Fechheimer M., Boylan J.F., Parker S., Sisken J.E., Patel G.L., Zimmer S.G. Transfection of mammalian cells with plasmid DNA by scrape loading and sonication loading. Proc Natl Acad Sci U S A 1987, 84:8463-8467.
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 8463-8467
-
-
Fechheimer, M.1
Boylan, J.F.2
Parker, S.3
Sisken, J.E.4
Patel, G.L.5
Zimmer, S.G.6
-
15
-
-
0030442881
-
A review of in vitro bioeffects of inertial ultrasonic cavitation from a mechanistic perspective
-
Miller M.W., Miller D.L., Brayman A.A. A review of in vitro bioeffects of inertial ultrasonic cavitation from a mechanistic perspective. Ultrasound Med Biol 1996, 22:1131-1154.
-
(1996)
Ultrasound Med Biol
, vol.22
, pp. 1131-1154
-
-
Miller, M.W.1
Miller, D.L.2
Brayman, A.A.3
-
16
-
-
33847768717
-
Gene therapy progress and prospects: ultrasound for gene transfer
-
Newman C.M., Bettinger T. Gene therapy progress and prospects: ultrasound for gene transfer. Gene Ther 2007, 14:465-475.
-
(2007)
Gene Ther
, vol.14
, pp. 465-475
-
-
Newman, C.M.1
Bettinger, T.2
-
17
-
-
48049096230
-
Ultrasound with microbubbles enhances gene expression of plasmid DNA in the liver via intraportal delivery
-
Shen Z.P., Brayman A.A., Chen L., Miao C.H. Ultrasound with microbubbles enhances gene expression of plasmid DNA in the liver via intraportal delivery. Gene Ther 2008, 15:1147-1155.
-
(2008)
Gene Ther
, vol.15
, pp. 1147-1155
-
-
Shen, Z.P.1
Brayman, A.A.2
Chen, L.3
Miao, C.H.4
-
18
-
-
0037066034
-
Local delivery of plasmid DNA into rat carotid artery using ultrasound
-
Taniyama Y., Tachibana K., Hiraoka K., Namba T., Yamasaki K., Hashiya N., Aoki M., Ogihara T., Yasufumi K., Morishita R. Local delivery of plasmid DNA into rat carotid artery using ultrasound. Circulation 2002, 105:1233-1239.
-
(2002)
Circulation
, vol.105
, pp. 1233-1239
-
-
Taniyama, Y.1
Tachibana, K.2
Hiraoka, K.3
Namba, T.4
Yamasaki, K.5
Hashiya, N.6
Aoki, M.7
Ogihara, T.8
Yasufumi, K.9
Morishita, R.10
-
19
-
-
33846510458
-
Gene delivery by combination of novel liposomal bubbles with perfluoropropane and ultrasound
-
Suzuki R., Takizawa T., Negishi Y., Hagisawa K., Tanaka K., Sawamura K., Utoguchi N., Nishioka T., Maruyama K. Gene delivery by combination of novel liposomal bubbles with perfluoropropane and ultrasound. J Control Release 2007, 117:130-136.
-
(2007)
J Control Release
, vol.117
, pp. 130-136
-
-
Suzuki, R.1
Takizawa, T.2
Negishi, Y.3
Hagisawa, K.4
Tanaka, K.5
Sawamura, K.6
Utoguchi, N.7
Nishioka, T.8
Maruyama, K.9
-
20
-
-
37349096583
-
Tumor specific ultrasound enhanced gene transfer in vivo with novel liposomal bubbles
-
Suzuki R., Takizawa T., Negishi Y., Utoguchi N., Sawamura K., Tanaka K., Namai E., Oda Y., Matsumura Y., Maruyama K. Tumor specific ultrasound enhanced gene transfer in vivo with novel liposomal bubbles. J Control Release 2008, 125:137-144.
-
(2008)
J Control Release
, vol.125
, pp. 137-144
-
-
Suzuki, R.1
Takizawa, T.2
Negishi, Y.3
Utoguchi, N.4
Sawamura, K.5
Tanaka, K.6
Namai, E.7
Oda, Y.8
Matsumura, Y.9
Maruyama, K.10
-
21
-
-
58549113776
-
A novel strategy utilizing ultrasound for antigen delivery in dendritic cell-based cancer immunotherapy
-
Suzuki R., Oda Y., Utoguchi N., Namai E., Taira Y., Okada N., Kadowaki N., Kodama T., Tachibana K., Maruyama K. A novel strategy utilizing ultrasound for antigen delivery in dendritic cell-based cancer immunotherapy. J Control Release 2009, 133:198-205.
-
(2009)
J Control Release
, vol.133
, pp. 198-205
-
-
Suzuki, R.1
Oda, Y.2
Utoguchi, N.3
Namai, E.4
Taira, Y.5
Okada, N.6
Kadowaki, N.7
Kodama, T.8
Tachibana, K.9
Maruyama, K.10
-
22
-
-
36448984350
-
A novel bubble liposome and ultrasound-mediated gene transfer to ocular surface: RC-1 cells in vitro and conjunctiva in vivo
-
Yamashita T., Sonoda S., Suzuki R., Arimura N., Tachibana K., Maruyama K., Sakamoto T. A novel bubble liposome and ultrasound-mediated gene transfer to ocular surface: RC-1 cells in vitro and conjunctiva in vivo. Exp Eye Res 2007, 85:741-748.
-
(2007)
Exp Eye Res
, vol.85
, pp. 741-748
-
-
Yamashita, T.1
Sonoda, S.2
Suzuki, R.3
Arimura, N.4
Tachibana, K.5
Maruyama, K.6
Sakamoto, T.7
-
23
-
-
56349123020
-
Delivery of siRNA into the cytoplasm by liposomal bubbles and ultrasound
-
Negishi Y., Endo Y., Fukuyama T., Suzuki R., Takizawa T., Omata D., Maruyama K., Aramaki Y. Delivery of siRNA into the cytoplasm by liposomal bubbles and ultrasound. J Control Release 2008, 132:124-130.
-
(2008)
J Control Release
, vol.132
, pp. 124-130
-
-
Negishi, Y.1
Endo, Y.2
Fukuyama, T.3
Suzuki, R.4
Takizawa, T.5
Omata, D.6
Maruyama, K.7
Aramaki, Y.8
-
24
-
-
74949097184
-
-
Enhanced transfection efficiency into macrophages and dendritic cells by the combination method using mannosylated lipoplexes and Bubble liposomes with ultrasound exposure Hum Gene Ther. In press.
-
K. Un, S. Kawakami, R. Suzuki, K. Maruyama, F. Yamashita, M. Hashida. Enhanced transfection efficiency into macrophages and dendritic cells by the combination method using mannosylated lipoplexes and Bubble liposomes with ultrasound exposure Hum Gene Ther. (2009) In press.
-
(2009)
-
-
Un S. Kawakami S. Suzuki R. Maruyama K. Yamashita F. Hashida, M.1
-
25
-
-
0024787403
-
Unstable expression of E-cadherin adhesion molecules in metastatic ovarian tumor cells
-
Hashimoto M., Niwa O., Nitta Y., Takeichi M., Yokoro K. Unstable expression of E-cadherin adhesion molecules in metastatic ovarian tumor cells. Jpn J Cancer Res 1989, 80:459-463.
-
(1989)
Jpn J Cancer Res
, vol.80
, pp. 459-463
-
-
Hashimoto, M.1
Niwa, O.2
Nitta, Y.3
Takeichi, M.4
Yokoro, K.5
-
26
-
-
0037040436
-
Fiber-mutant technique can augment gene transduction efficacy and anti-tumor effects against established murine melanoma by cytokine-gene therapy using adenovirus vectors
-
Okada Y., Okada N., Nakagawa S., Mizuguchi H., Kanehira M., Nishino N., Takahashi K., Mizuno N., Hayakawa T., Mayumi T. Fiber-mutant technique can augment gene transduction efficacy and anti-tumor effects against established murine melanoma by cytokine-gene therapy using adenovirus vectors. Cancer Lett 2002, 177:57-63.
-
(2002)
Cancer Lett
, vol.177
, pp. 57-63
-
-
Okada, Y.1
Okada, N.2
Nakagawa, S.3
Mizuguchi, H.4
Kanehira, M.5
Nishino, N.6
Takahashi, K.7
Mizuno, N.8
Hayakawa, T.9
Mayumi, T.10
-
27
-
-
0037832252
-
Suicide gene therapy mediated by the Herpes Simplex virus thymidine kinase gene/Ganciclovir system: fifteen years of application
-
Fillat C., Carrio M., Cascante A., Sangro B. Suicide gene therapy mediated by the Herpes Simplex virus thymidine kinase gene/Ganciclovir system: fifteen years of application. Curr Gene Ther 2003, 3:13-26.
-
(2003)
Curr Gene Ther
, vol.3
, pp. 13-26
-
-
Fillat, C.1
Carrio, M.2
Cascante, A.3
Sangro, B.4
-
28
-
-
60149095359
-
Combined silencing of K-ras and Akt2 oncogenes achieves synergistic effects in inhibiting pancreatic cancer cell growth in vitro and in vivo
-
Shi X.H., Liang Z.Y., Ren X.Y., Liu T.H. Combined silencing of K-ras and Akt2 oncogenes achieves synergistic effects in inhibiting pancreatic cancer cell growth in vitro and in vivo. Cancer Gene Ther 2009, 16:227-236.
-
(2009)
Cancer Gene Ther
, vol.16
, pp. 227-236
-
-
Shi, X.H.1
Liang, Z.Y.2
Ren, X.Y.3
Liu, T.H.4
-
29
-
-
20144387142
-
Intravesical administration of small interfering RNA targeting PLK-1 successfully prevents the growth of bladder cancer
-
Nogawa M., Yuasa T., Kimura S., Tanaka M., Kuroda J., Sato K., Yokota A., Segawa H., Toda Y., Kageyama S., Yoshiki T., Okada Y., Maekawa T. Intravesical administration of small interfering RNA targeting PLK-1 successfully prevents the growth of bladder cancer. J Clin Invest 2005, 115:978-985.
-
(2005)
J Clin Invest
, vol.115
, pp. 978-985
-
-
Nogawa, M.1
Yuasa, T.2
Kimura, S.3
Tanaka, M.4
Kuroda, J.5
Sato, K.6
Yokota, A.7
Segawa, H.8
Toda, Y.9
Kageyama, S.10
Yoshiki, T.11
Okada, Y.12
Maekawa, T.13
-
30
-
-
58749105627
-
Efficient delivery of Bcl-2-targeted siRNA using cationic polymer nanoparticles: downregulating mRNA expression level and sensitizing cancer cells to anticancer drug
-
Beh C.W., Seow W.Y., Wang Y., Zhang Y., Ong Z.Y., Ee P.L., Yang Y.Y. Efficient delivery of Bcl-2-targeted siRNA using cationic polymer nanoparticles: downregulating mRNA expression level and sensitizing cancer cells to anticancer drug. Biomacromolecules 2009, 10:41-48.
-
(2009)
Biomacromolecules
, vol.10
, pp. 41-48
-
-
Beh, C.W.1
Seow, W.Y.2
Wang, Y.3
Zhang, Y.4
Ong, Z.Y.5
Ee, P.L.6
Yang, Y.Y.7
-
31
-
-
64549110321
-
RNA interference-mediated validation of genes involved in telomere maintenance and evasion of apoptosis as cancer therapeutic targets
-
Folini M., Pennati M., Zaffaroni N. RNA interference-mediated validation of genes involved in telomere maintenance and evasion of apoptosis as cancer therapeutic targets. Methods Mol Biol 2009, 487:303-330.
-
(2009)
Methods Mol Biol
, vol.487
, pp. 303-330
-
-
Folini, M.1
Pennati, M.2
Zaffaroni, N.3
-
32
-
-
0033533669
-
Virus treatment questioned after gene therapy death
-
Lehrman S. Virus treatment questioned after gene therapy death. Nature 1999, 401:517-518.
-
(1999)
Nature
, vol.401
, pp. 517-518
-
-
Lehrman, S.1
-
33
-
-
33645873289
-
Recent advances in non-viral gene delivery
-
PA
-
Conwell C.C., Huang L. Recent advances in non-viral gene delivery. Adv Genet 2005, 53PA:1-18.
-
(2005)
Adv Genet
, vol.53
, pp. 1-18
-
-
Conwell, C.C.1
Huang, L.2
-
34
-
-
45449098667
-
Antitumor mechanism of intratumoral injection with IL-12-expressing adenoviral vector against IL-12-unresponsive tumor
-
Kanagawa N., Gao J.Q., Motomura Y., Yanagawa T., Mukai Y., Yoshioka Y., Okada N., Nakagawa S. Antitumor mechanism of intratumoral injection with IL-12-expressing adenoviral vector against IL-12-unresponsive tumor. Biochem Biophys Res Commun 2008, 372:821-825.
-
(2008)
Biochem Biophys Res Commun
, vol.372
, pp. 821-825
-
-
Kanagawa, N.1
Gao, J.Q.2
Motomura, Y.3
Yanagawa, T.4
Mukai, Y.5
Yoshioka, Y.6
Okada, N.7
Nakagawa, S.8
|