메뉴 건너뛰기




Volumn 13, Issue 1, 2014, Pages

ADAM17 mediates OSCC development in an orthotopic murine model

Author keywords

[No Author keywords available]

Indexed keywords

ADAM PROTEINS; ANIMALS; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CELL ADHESION; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; GENE KNOCKDOWN TECHNIQUES; HETEROGRAFTS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED BALB C; MOUTH NEOPLASMS; PROTEOMICS; REAL-TIME POLYMERASE CHAIN REACTION; TRANSFECTION;

EID: 84893203138     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-13-24     Document Type: Article
Times cited : (16)

References (50)
  • 1
    • 56749133149 scopus 로고    scopus 로고
    • The ADAMs: signalling scissors in the tumour microenvironment
    • Murphy G. The ADAMs: signalling scissors in the tumour microenvironment. Nat Rev Cancer 2008, 8:929-941.
    • (2008) Nat Rev Cancer , vol.8 , pp. 929-941
    • Murphy, G.1
  • 2
    • 77949558495 scopus 로고    scopus 로고
    • ADAM-17: the enzyme that does it all
    • 10.3109/10409231003628015, 2841225, 20184396
    • Gooz M. ADAM-17: the enzyme that does it all. Crit Rev Biochem Mol Biol 2010, 45:146-169. 10.3109/10409231003628015, 2841225, 20184396.
    • (2010) Crit Rev Biochem Mol Biol , vol.45 , pp. 146-169
    • Gooz, M.1
  • 3
    • 52949099119 scopus 로고    scopus 로고
    • The ADAM metalloproteinases
    • 10.1016/j.mam.2008.08.001, 18762209
    • Edwards DR, Handsley MM, Pennington CJ. The ADAM metalloproteinases. Mol Aspects Med 2008, 29:258-289. 10.1016/j.mam.2008.08.001, 18762209.
    • (2008) Mol Aspects Med , vol.29 , pp. 258-289
    • Edwards, D.R.1    Handsley, M.M.2    Pennington, C.J.3
  • 4
    • 63149117373 scopus 로고    scopus 로고
    • Role of ADAMs in cancer formation and progression
    • 10.1158/1078-0432.CCR-08-1585, 19228719
    • Duffy MJ, McKiernan E, O'Donovan N, McGowan PM. Role of ADAMs in cancer formation and progression. Clin Cancer Res 2009, 15:1140-1144. 10.1158/1078-0432.CCR-08-1585, 19228719.
    • (2009) Clin Cancer Res , vol.15 , pp. 1140-1144
    • Duffy, M.J.1    McKiernan, E.2    O'Donovan, N.3    McGowan, P.M.4
  • 5
    • 11244261160 scopus 로고    scopus 로고
    • ADAMs: key components in EGFR signalling and development
    • 10.1038/nrm1548, 15688065
    • Blobel CP. ADAMs: key components in EGFR signalling and development. Nat Rev Mol Cell Biol 2005, 6:32-43. 10.1038/nrm1548, 15688065.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 32-43
    • Blobel, C.P.1
  • 8
    • 84874909578 scopus 로고    scopus 로고
    • Oral cancer: current role of radiotherapy and chemotherapy
    • Huang S, O Sullivan B. Oral cancer: current role of radiotherapy and chemotherapy. Med Oral Patol Oral y Cir Bucal 2013, 18:e233-e240.
    • (2013) Med Oral Patol Oral y Cir Bucal , vol.18
    • Huang, S.1    Sullivan, B.2
  • 9
    • 1642633685 scopus 로고    scopus 로고
    • The world oral health report 2003: continuous improvement of oral health in the 21st century-the approach of the WHO global oral health programme
    • Petersen PE. The world oral health report 2003: continuous improvement of oral health in the 21st century-the approach of the WHO global oral health programme. Community Dent Oral Epidemiol 2003, 31(Suppl 1):3-23.
    • (2003) Community Dent Oral Epidemiol , vol.31 , Issue.SUPPL 1 , pp. 3-23
    • Petersen, P.E.1
  • 10
    • 0038581051 scopus 로고    scopus 로고
    • TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells
    • 10.1093/emboj/cdg231, 155989, 12743035
    • Gschwind A, Hart S, Fischer O, Ullrich A. TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells. EMBO J 2003, 22:2411-2421. 10.1093/emboj/cdg231, 155989, 12743035.
    • (2003) EMBO J , vol.22 , pp. 2411-2421
    • Gschwind, A.1    Hart, S.2    Fischer, O.3    Ullrich, A.4
  • 11
    • 80052265882 scopus 로고    scopus 로고
    • Myofibroblasts in the stroma of oral cancer promote tumorigenesis via secretion of activin A
    • 10.1016/j.oraloncology.2011.06.011, 21727023
    • Sobral LM, Bufalino A, Lopes M, Graner E, Salo T, Coletta RD. Myofibroblasts in the stroma of oral cancer promote tumorigenesis via secretion of activin A. Oral Oncol 2011, 47:840-846. 10.1016/j.oraloncology.2011.06.011, 21727023.
    • (2011) Oral Oncol , vol.47 , pp. 840-846
    • Sobral, L.M.1    Bufalino, A.2    Lopes, M.3    Graner, E.4    Salo, T.5    Coletta, R.D.6
  • 12
    • 84855544503 scopus 로고    scopus 로고
    • Hemorrhagic activity of HF3, a snake venom metalloproteinase: insights from the proteomic analysis of mouse skin and blood plasma
    • 10.1021/pr2006439, 21939285
    • Paes Leme AF, Sherman NE, Smalley DM, Sizukusa LO, Oliveira AK, Menezes MC, Fox JW, Serrano SMT. Hemorrhagic activity of HF3, a snake venom metalloproteinase: insights from the proteomic analysis of mouse skin and blood plasma. J Proteome Res 2012, 11:279-291. 10.1021/pr2006439, 21939285.
    • (2012) J Proteome Res , vol.11 , pp. 279-291
    • Paes Leme, A.F.1    Sherman, N.E.2    Smalley, D.M.3    Sizukusa, L.O.4    Oliveira, A.K.5    Menezes, M.C.6    Fox, J.W.7    Serrano, S.M.T.8
  • 13
    • 34548183872 scopus 로고    scopus 로고
    • Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips
    • 10.1038/nprot.2007.261, 17703201
    • Rappsilber J, Mann M, Ishihama Y. Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips. Nat Protoc 2007, 2:1896-1906. 10.1038/nprot.2007.261, 17703201.
    • (2007) Nat Protoc , vol.2 , pp. 1896-1906
    • Rappsilber, J.1    Mann, M.2    Ishihama, Y.3
  • 15
    • 57449099865 scopus 로고    scopus 로고
    • MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
    • 10.1038/nbt.1511, 19029910
    • Cox J, Mann M. MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification. Nat Biotechnol 2008, 26:1367-1372. 10.1038/nbt.1511, 19029910.
    • (2008) Nat Biotechnol , vol.26 , pp. 1367-1372
    • Cox, J.1    Mann, M.2
  • 16
    • 79953701087 scopus 로고    scopus 로고
    • Andromeda: a peptide search engine integrated into the MaxQuant environment
    • 10.1021/pr101065j, 21254760
    • Cox J, Neuhauser N, Michalski A, Scheltema R, Olsen JV, Mann M. Andromeda: a peptide search engine integrated into the MaxQuant environment. J Proteome Res 2011, 10:1794-1805. 10.1021/pr101065j, 21254760.
    • (2011) J Proteome Res , vol.10 , pp. 1794-1805
    • Cox, J.1    Neuhauser, N.2    Michalski, A.3    Scheltema, R.4    Olsen, J.V.5    Mann, M.6
  • 18
    • 78649757591 scopus 로고    scopus 로고
    • ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site
    • 2972273, 20980382
    • Le Gall SM, Maretzky T, Issuree PD, Niu X-D, Reiss K, Saftig P, Khokha R, Lundell D, Blobel CP. ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site. J Cell Sci 2010, 123(Pt 22):3913-3922. 2972273, 20980382.
    • (2010) J Cell Sci , vol.123 , Issue.PART 22 , pp. 3913-3922
    • Le Gall, S.M.1    Maretzky, T.2    Issuree, P.D.3    Niu, X.D.4    Reiss, K.5    Saftig, P.6    Khokha, R.7    Lundell, D.8    Blobel, C.P.9
  • 21
    • 39449130768 scopus 로고    scopus 로고
    • ADAM15 supports prostate cancer metastasis by modulating tumor cell-endothelial cell interaction
    • 10.1158/0008-5472.CAN-07-2432, 18281484
    • Najy AJ, Day KC, Day ML. ADAM15 supports prostate cancer metastasis by modulating tumor cell-endothelial cell interaction. Cancer Res 2008, 68:1092-1099. 10.1158/0008-5472.CAN-07-2432, 18281484.
    • (2008) Cancer Res , vol.68 , pp. 1092-1099
    • Najy, A.J.1    Day, K.C.2    Day, M.L.3
  • 22
    • 79952480540 scopus 로고    scopus 로고
    • Migration of growth factor-stimulated epithelial and endothelial cells depends on EGFR transactivation by ADAM17
    • 3074487, 21407195
    • Maretzky T, Evers A, Zhou W, Swendeman SL, Wong P-M, Rafii S, Reiss K, Blobel CP. Migration of growth factor-stimulated epithelial and endothelial cells depends on EGFR transactivation by ADAM17. Nat Commun 2011, 2:229. 3074487, 21407195.
    • (2011) Nat Commun , vol.2 , pp. 229
    • Maretzky, T.1    Evers, A.2    Zhou, W.3    Swendeman, S.L.4    Wong, P.M.5    Rafii, S.6    Reiss, K.7    Blobel, C.P.8
  • 23
    • 84855225471 scopus 로고    scopus 로고
    • ADAM17 promotes glioma cell malignant phenotype
    • 10.1002/mc.20772, 3234333, 21480393
    • Zheng X, Jiang F, Katakowski M, Lu Y, Chopp M. ADAM17 promotes glioma cell malignant phenotype. Mol Carcinog 2012, 51:150-164. 10.1002/mc.20772, 3234333, 21480393.
    • (2012) Mol Carcinog , vol.51 , pp. 150-164
    • Zheng, X.1    Jiang, F.2    Katakowski, M.3    Lu, Y.4    Chopp, M.5
  • 25
    • 83555174918 scopus 로고    scopus 로고
    • ADAM17 regulates prostate cancer cell proliferation through mediating cell cycle progression by EGFR/PI3K/AKT pathway
    • 10.1007/s11010-011-1018-8, 21837402
    • Lin P, Sun X, Feng T, Zou H, Jiang Y, Liu Z, Zhao D, Yu X. ADAM17 regulates prostate cancer cell proliferation through mediating cell cycle progression by EGFR/PI3K/AKT pathway. Mol Cell Biochem 2012, 359:235-243. 10.1007/s11010-011-1018-8, 21837402.
    • (2012) Mol Cell Biochem , vol.359 , pp. 235-243
    • Lin, P.1    Sun, X.2    Feng, T.3    Zou, H.4    Jiang, Y.5    Liu, Z.6    Zhao, D.7    Yu, X.8
  • 26
    • 84877688937 scopus 로고    scopus 로고
    • Hydrogen sulfide reduces cell adhesion and relevant inflammatory triggering by preventing ADAM17-dependent TNF-α activation
    • 10.1002/jcb.24495, 23297114
    • Perna AF, Sepe I, Lanza D, Capasso R, Zappavigna S, Capasso G, Caraglia M, Ingrosso D. Hydrogen sulfide reduces cell adhesion and relevant inflammatory triggering by preventing ADAM17-dependent TNF-α activation. J Cell Biochem 2013, 114:1536-1548. 10.1002/jcb.24495, 23297114.
    • (2013) J Cell Biochem , vol.114 , pp. 1536-1548
    • Perna, A.F.1    Sepe, I.2    Lanza, D.3    Capasso, R.4    Zappavigna, S.5    Capasso, G.6    Caraglia, M.7    Ingrosso, D.8
  • 30
    • 78650876660 scopus 로고    scopus 로고
    • Overexpression of TACE and TIMP3 mRNA in head and neck cancer: association with tumour development and progression
    • 10.1038/sj.bjc.6606017, 3039790, 21102583
    • Kornfeld J-W, Meder S, Wohlberg M, Friedrich RE, Rau T, Riethdorf L, Löning T, Pantel K, Riethdorf S. Overexpression of TACE and TIMP3 mRNA in head and neck cancer: association with tumour development and progression. Br J Cancer 2011, 104:138-145. 10.1038/sj.bjc.6606017, 3039790, 21102583.
    • (2011) Br J Cancer , vol.104 , pp. 138-145
    • Kornfeld, J.W.1    Meder, S.2    Wohlberg, M.3    Friedrich, R.E.4    Rau, T.5    Riethdorf, L.6    Löning, T.7    Pantel, K.8    Riethdorf, S.9
  • 31
    • 80255129266 scopus 로고    scopus 로고
    • Endothelin-1 stimulates motility of head and neck squamous carcinoma cells by promoting stromal-epithelial interactions
    • 10.1002/ijc.25968, 21491424
    • Hinsley EE, Hunt S, Hunter KD, Whawell SA, Lambert DW. Endothelin-1 stimulates motility of head and neck squamous carcinoma cells by promoting stromal-epithelial interactions. Int J Cancer 2012, 130:40-47. 10.1002/ijc.25968, 21491424.
    • (2012) Int J Cancer , vol.130 , pp. 40-47
    • Hinsley, E.E.1    Hunt, S.2    Hunter, K.D.3    Whawell, S.A.4    Lambert, D.W.5
  • 32
    • 84878610693 scopus 로고    scopus 로고
    • MiR145 Targets the SOX9/ADAM17 axis to inhibit tumor-initiating cells and IL-6-mediated paracrine effects in head and neck cancer
    • Yu C-C, Tsai L-L, Wang M-L, Yu C-H, Lo W-L, Chang Y-C, Chiou G-Y, Chou M-Y, Chiou S-H S-H. miR145 Targets the SOX9/ADAM17 axis to inhibit tumor-initiating cells and IL-6-mediated paracrine effects in head and neck cancer. Cancer Res 2013, 71:3425-3440.
    • (2013) Cancer Res , vol.71 , pp. 3425-3440
    • Yu, C.C.1    Tsai, L.L.2    Wang, M.L.3    Yu, C.H.4    Lo, W.L.5    Chang, Y.C.6    Chiou, G.Y.7    Chou, M.Y.8    Chiou, S.-H.9
  • 33
    • 84863227112 scopus 로고    scopus 로고
    • Nucleoplasmic calcium buffering sensitizes human squamous cell carcinoma to anticancer therapy
    • M Andrade L, Geraldo JM. Nucleoplasmic calcium buffering sensitizes human squamous cell carcinoma to anticancer therapy. J Cancer Sci Ther 2012, 04:131-139.
    • (2012) J Cancer Sci Ther , vol.4 , pp. 131-139
    • Andrade, L.1    Geraldo, J.M.2
  • 35
    • 84862294189 scopus 로고    scopus 로고
    • ERK1/2 MAP kinases: structure, function, and regulation
    • 10.1016/j.phrs.2012.04.005, 22569528
    • Roskoski R. ERK1/2 MAP kinases: structure, function, and regulation. Pharmacol Res 2012, 66:105-143. 10.1016/j.phrs.2012.04.005, 22569528.
    • (2012) Pharmacol Res , vol.66 , pp. 105-143
    • Roskoski, R.1
  • 37
    • 80053175737 scopus 로고    scopus 로고
    • Downregulation of E-Cadherin enhances proliferation of head and neck cancer through transcriptional regulation of EGFR
    • 10.1186/1476-4598-10-116, 3192774, 21939503
    • Wang D, Su L, Huang D, Zhang H, Shin DM, Chen ZG. Downregulation of E-Cadherin enhances proliferation of head and neck cancer through transcriptional regulation of EGFR. Mol Cancer 2011, 10:116. 10.1186/1476-4598-10-116, 3192774, 21939503.
    • (2011) Mol Cancer , vol.10 , pp. 116
    • Wang, D.1    Su, L.2    Huang, D.3    Zhang, H.4    Shin, D.M.5    Chen, Z.G.6
  • 38
    • 84864764964 scopus 로고    scopus 로고
    • Differentiation-induced skin cancer suppression by FOS, p53, and TACE/ADAM17
    • 10.1172/JCI63103, 3408745, 22772468
    • Guinea-Viniegra J, Zenz R, Scheuch H, Jiménez M, Bakiri L, Petzelbauer P, Wagner EF. Differentiation-induced skin cancer suppression by FOS, p53, and TACE/ADAM17. J Clin Invest 2012, 122:2898-2910. 10.1172/JCI63103, 3408745, 22772468.
    • (2012) J Clin Invest , vol.122 , pp. 2898-2910
    • Guinea-Viniegra, J.1    Zenz, R.2    Scheuch, H.3    Jiménez, M.4    Bakiri, L.5    Petzelbauer, P.6    Wagner, E.F.7
  • 39
    • 84858726313 scopus 로고    scopus 로고
    • Regulation of cell death and autophagy by IKK and NF-κB: critical mechanisms in immune function and cancer
    • 10.1111/j.1600-065X.2012.01095.x, 22435564
    • Baldwin AS. Regulation of cell death and autophagy by IKK and NF-κB: critical mechanisms in immune function and cancer. Immunol Rev 2012, 246:327-345. 10.1111/j.1600-065X.2012.01095.x, 22435564.
    • (2012) Immunol Rev , vol.246 , pp. 327-345
    • Baldwin, A.S.1
  • 40
    • 80054712946 scopus 로고    scopus 로고
    • IKKβ overexpression leads to pathologic lesions in stratified epithelia and exocrine glands and to tumoral transformation of oral epithelia
    • 10.1158/1541-7786.MCR-11-0168, 21821676
    • Page A, Cascallana JL, Casanova ML, Navarro M, Alameda JP, Pérez P, Bravo A, Ramírez A. IKKβ overexpression leads to pathologic lesions in stratified epithelia and exocrine glands and to tumoral transformation of oral epithelia. Mol Cancer Res 2011, 9:1329-1338. 10.1158/1541-7786.MCR-11-0168, 21821676.
    • (2011) Mol Cancer Res , vol.9 , pp. 1329-1338
    • Page, A.1    Cascallana, J.L.2    Casanova, M.L.3    Navarro, M.4    Alameda, J.P.5    Pérez, P.6    Bravo, A.7    Ramírez, A.8
  • 41
    • 42549157959 scopus 로고    scopus 로고
    • Gypenosides inhibited invasion and migration of human tongue cancer SCC4 cells through down-regulation of NFkappaB and matrix metalloproteinase-9
    • Lu K-W, Tsai M-L, Chen J-C, Hsu S-C, Hsia T-C, Lin M-W, Huang A-C, Chang Y-H, Ip S-W, Lu H-F, Chung J-G. Gypenosides inhibited invasion and migration of human tongue cancer SCC4 cells through down-regulation of NFkappaB and matrix metalloproteinase-9. Anticancer Res 2008, 28:1093-1099.
    • (2008) Anticancer Res , vol.28 , pp. 1093-1099
    • Lu, K.W.1    Tsai, M.L.2    Chen, J.C.3    Hsu, S.C.4    Hsia, T.C.5    Lin, M.W.6    Huang, A.C.7    Chang, Y.H.8    Ip, S.W.9    Lu, H.F.10    Chung, J.G.11
  • 44
    • 0033599039 scopus 로고    scopus 로고
    • EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF
    • Prenzel N, Zwick E, Daub H, Leserer M, Abraham R, Wallasch C, Ullrich A. EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. Nature 1999, 402:884-888.
    • (1999) Nature , vol.402 , pp. 884-888
    • Prenzel, N.1    Zwick, E.2    Daub, H.3    Leserer, M.4    Abraham, R.5    Wallasch, C.6    Ullrich, A.7
  • 45
    • 4344610825 scopus 로고    scopus 로고
    • SRC family kinases mediate epidermal growth factor receptor ligand cleavage, proliferation, and invasion of head and neck cancer cells
    • 10.1158/0008-5472.CAN-04-0504, 15342401
    • Zhang Q, Thomas SM, Xi S, Smithgall TE, Siegfried JM, Kamens J, Gooding WE, Grandis JR. SRC family kinases mediate epidermal growth factor receptor ligand cleavage, proliferation, and invasion of head and neck cancer cells. Cancer Res 2004, 64:6166-6173. 10.1158/0008-5472.CAN-04-0504, 15342401.
    • (2004) Cancer Res , vol.64 , pp. 6166-6173
    • Zhang, Q.1    Thomas, S.M.2    Xi, S.3    Smithgall, T.E.4    Siegfried, J.M.5    Kamens, J.6    Gooding, W.E.7    Grandis, J.R.8
  • 47
    • 84867610233 scopus 로고    scopus 로고
    • Epidermal growth factor (EGF) and interleukin (IL)-1β synergistically promote ERK1/2-mediated invasive breast ductal cancer cell migration and invasion
    • 10.1186/1476-4598-11-79, 3537707, 23083134
    • Ma L, Lan F, Zheng Z, Xie F, Wang L, Liu W, Han J, Zheng F, Xie Y, Huang Q. Epidermal growth factor (EGF) and interleukin (IL)-1β synergistically promote ERK1/2-mediated invasive breast ductal cancer cell migration and invasion. Mol Cancer 2012, 11:79. 10.1186/1476-4598-11-79, 3537707, 23083134.
    • (2012) Mol Cancer , vol.11 , pp. 79
    • Ma, L.1    Lan, F.2    Zheng, Z.3    Xie, F.4    Wang, L.5    Liu, W.6    Han, J.7    Zheng, F.8    Xie, Y.9    Huang, Q.10
  • 48
    • 78650831923 scopus 로고    scopus 로고
    • MMP-2 mediates angiotensin II-induced hypertension under the transcriptional control of MMP-7 and TACE
    • 10.1161/HYPERTENSIONAHA.110.159525, 21079048
    • Odenbach J, Wang X, Cooper S, Chow FL, Oka T, Lopaschuk G, Kassiri Z, Fernandez-Patron C. MMP-2 mediates angiotensin II-induced hypertension under the transcriptional control of MMP-7 and TACE. Hypertension 2011, 57:123-130. 10.1161/HYPERTENSIONAHA.110.159525, 21079048.
    • (2011) Hypertension , vol.57 , pp. 123-130
    • Odenbach, J.1    Wang, X.2    Cooper, S.3    Chow, F.L.4    Oka, T.5    Lopaschuk, G.6    Kassiri, Z.7    Fernandez-Patron, C.8
  • 49
    • 70349254243 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha-converting enzyme is a key regulator of agonist-induced cardiac hypertrophy and fibrosis
    • 10.1161/HYPERTENSIONAHA.108.127670, 19581512
    • Wang X, Oka T, Chow FL, Cooper SB, Odenbach J, Lopaschuk GD, Kassiri Z, Fernandez-Patron C. Tumor necrosis factor-alpha-converting enzyme is a key regulator of agonist-induced cardiac hypertrophy and fibrosis. Hypertension 2009, 54:575-582. 10.1161/HYPERTENSIONAHA.108.127670, 19581512.
    • (2009) Hypertension , vol.54 , pp. 575-582
    • Wang, X.1    Oka, T.2    Chow, F.L.3    Cooper, S.B.4    Odenbach, J.5    Lopaschuk, G.D.6    Kassiri, Z.7    Fernandez-Patron, C.8
  • 50
    • 84860289206 scopus 로고    scopus 로고
    • ADAM17 targets MMP-2 and MMP-9 via EGFR-MEK-ERK pathway activation to promote prostate cancer cell invasion
    • Xiao L-J, Lin P, Lin F, Liu X, Qin W, Zou H-F, Guo L, Liu W, Wang S-J, Yu X-G. ADAM17 targets MMP-2 and MMP-9 via EGFR-MEK-ERK pathway activation to promote prostate cancer cell invasion. Int J Oncol 2012, 40:1714-1724.
    • (2012) Int J Oncol , vol.40 , pp. 1714-1724
    • Xiao, L.J.1    Lin, P.2    Lin, F.3    Liu, X.4    Qin, W.5    Zou, H.F.6    Guo, L.7    Liu, W.8    Wang, S.J.9    Yu, X.G.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.