Endothelin-1 stimulates motility of head and neck squamous carcinoma cells by promoting stromal-epithelial interactions

International Journal of Cancer

Volumn 130, Issue 1, 2012, Pages 40-47

  Hinsley, Emma E ^a   Hunt, Stuart ^a   Hunter, Keith D ^a   Whawell, Simon A ^a   Lambert, Daniel W ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

EGFR transactivation; endothelin; head and neck cancer; metastasis; migration; stromal epithelial interaction

Indexed keywords

ADAM PROTEIN; ADAM10 ENDOPEPTIDASE; ADAM15 PROTEIN; ADAM17 PROTEIN; ADAM9 PROTEIN; CYCLOOXYGENASE 2; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CARCINOGENESIS; CELL INTERACTION; CELL LEVEL; CELL MIGRATION; CELL MOTILITY; CELL STIMULATION; CONTROLLED STUDY; FIBROBLAST; HEAD AND NECK CARCINOMA; METASTASIS; MOLECULAR INTERACTION; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA; STROMAL EPITHELIAL INTERACTION; TRANSACTIVATION;

ADAM PROTEINS; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CELL COMMUNICATION; CELL MOVEMENT; CELLS, CULTURED; CYCLOOXYGENASE 2; ENDOTHELIN-1; EPITHELIAL CELLS; FEMALE; FIBROBLASTS; HEAD AND NECK NEOPLASMS; HUMANS; MOUTH; PARACRINE COMMUNICATION; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA, MESSENGER; SIGNAL TRANSDUCTION; STROMAL CELLS;

EID: 80255129266     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.25968     Document Type: Article

References (29)

1. Joyce JA, Pollard JW,. Microenvironmental regulation of metastasis. Nat Rev Cancer 2009; 9: 239-52.
2. Pietras K, Ostman A,. Hallmarks of cancer: interactions with the tumor stroma. Exp Cell Res.
3. Kalluri R, Zeisberg M,. Fibroblasts in cancer. Nat Rev Cancer 2006; 6: 392-401.
4. Vedtofte P, Holmstrup P, Hjorting-Hansen E, Pindborg JJ,. Surgical treatment of premalignant lesions of the oral mucosa. Int J Oral Maxillofac Surg 1987; 16: 656-64. (Pubitemid 18025813)
5. Thomas SM, Bhola NE, Zhang Q, Contrucci SC, Wentzel AL, Freilino ML, Gooding WE, Siegfried JM, Chan DC, Grandis JR,. Cross-talk between G protein-coupled receptor and epidermal growth factor receptor signaling pathways contributes to growth and invasion of head and neck squamous cell carcinoma. Cancer Res 2006; 66: 11831-9. (Pubitemid 46094195)
6. Lango MN, Dyer KF, Lui VW, Gooding WE, Gubish C, Siegfried JM, Grandis JR,. Gastrin-releasing peptide receptor-mediated autocrine growth in squamous cell carcinoma of the head and neck. J Natl Cancer Inst 2002; 94: 375-83. (Pubitemid 34257481)
7. Fischer OM, Hart S, Gschwind A, Ullrich A,. EGFR signal transactivation in cancer cells. Biochem Soc Trans 2003; 31: 1203-8. (Pubitemid 38030939)
8. Murphy G,. The ADAMs: signalling scissors in the tumour microenvironment. Nat Rev Cancer 2008; 8: 929-41.
9. Lambert LA, Whyteside AR, Turner AJ, Usmani BA,. Isoforms of endothelin-converting enzyme-1 (ECE-1) have opposing effects on prostate cancer cell invasion. Br J Cancer 2008; 99: 1114-20.
10. Awano S, Dawson LA, Hunter AR, Turner AJ, Usmani BA,. Endothelin system in oral squamous carcinoma cells: specific siRNA targeting of ECE-1 blocks cell proliferation. Int J Cancer 2006; 118: 1645-52. (Pubitemid 43376427)
11. Dawson LA, Maitland NJ, Berry P, Turner AJ, Usmani BA,. Expression and localization of endothelin-converting enzyme-1 in human prostate cancer. Exp Biol Med (Maywood) 2006; 231: 1106-10. (Pubitemid 43845587)
12. Bagnato A, Rosano L,. The endothelin axis in cancer. Int J Biochem Cell Biol 2008; 40: 1443-51.
13. Bagnato A, Rosano L,. Epithelial-mesenchymal transition in ovarian cancer progression: a crucial role for the endothelin axis. Cells Tissues Organs 2007; 185: 85-94. (Pubitemid 46956847)
14. Dawson LA, Maitland NJ, Turner AJ, Usmani BA,. Stromal-epithelial interactions influence prostate cancer cell invasion by altering the balance of metallopeptidase expression. Br J Cancer 2004; 90: 1577-82. (Pubitemid 38648241)
15. Hearnden V, Lomas H, Macneil S, Thornhill M, Murdoch C, Lewis A, Madsen J, Blanazs A, Armes S, Battaglia G,. Diffusion studies of nanometer polymersomes across tissue engineered human oral mucosa. Pharm Res 2009; 26: 1718-28.
16. Montgomery JP, Patterson PH,. Endothelin receptor B antagonists decrease glioma cell viability independently of their cognate receptor. BMC Cancer 2008; 8: 354.
17. Wakimoto N, Wolf I, Yin D, O'Kelly J, Akagi T, Abramovitz L, Black KL, Tai HH, Koeffler HP,. Nonsteroidal anti-inflammatory drugs suppress glioma via 15-hydroxyprostaglandin dehydrogenase. Cancer Res 2008; 68: 6978-86.
18. Chan G, Boyle JO, Yang EK, Zhang F, Sacks PG, Shah JP, Edelstein D, Soslow RA, Koki AT, Woerner BM, Masferrer JL, Dannenberg AJ,. Cyclooxygenase-2 expression is up-regulated in squamous cell carcinoma of the head and neck. Cancer Res 1999; 59: 991-4. (Pubitemid 29135955)
19. Zhang W, Bhola N, Kalyankrishna S, Gooding W, Hunt J, Seethala R, Grandis JR, Siegfried JM,. Kinin b2 receptor mediates induction of cyclooxygenase-2 and is overexpressed in head and neck squamous cell carcinomas. Mol Cancer Res 2008; 6: 1946-56.
20. Pickering V, Jordan RC, Schmidt BL,. Elevated salivary endothelin levels in oral cancer patients-a pilot study. Oral Oncol 2007; 43: 37-41. (Pubitemid 46162247)
21. Bhalla A, Haque S, Taylor I, Winslet M, Loizidou M,. Endothelin receptor antagonism and cancer. Eur J Clin Invest 2009; 39 (Suppl 2): 74-7.
22. Nelson J, Bagnato A, Battistini B, Nisen P,. The endothelin axis: emerging role in cancer. Nat Rev Cancer 2003; 3: 110-6. (Pubitemid 37328878)
23. Resink TJ, Scott-Burden T, Buhler FR,. Endothelin stimulates phospholipase C in cultured vascular smooth muscle cells. Biochem Biophys Res Commun 1988; 157: 1360-8. (Pubitemid 19026007)
24. Daher Z, Noel J, Claing A,. Endothelin-1 promotes migration of endothelial cells through the activation of ARF6 and the regulation of FAK activity. Cell Signal 2008; 20: 2256-65.
25. Rosano L, Cianfrocca R, Masi S, Spinella F, Di Castro V, Biroccio A, Salvati E, Nicotra MR, Natali PG, Bagnato A,. Beta-arrestin links endothelin A receptor to beta-catenin signaling to induce ovarian cancer cell invasion and metastasis. Proc Natl Acad Sci USA 2009; 106: 2806-11.
26. Prenzel N, Zwick E, Daub H, Leserer M, Abraham R, Wallasch C, Ullrich A,. EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. Nature 1999; 402: 884-8.
27. Kalyankrishna S, Grandis JR,. Epidermal growth factor receptor biology in head and neck cancer. J Clin Oncol 2006; 24: 2666-72. (Pubitemid 46622088)
28. Wang D, Buchanan FG, Wang H, Dey SK, DuBois RN,. Prostaglandin E2 enhances intestinal adenoma growth via activation of the Ras-mitogen-activated protein kinase cascade. Cancer Res 2005; 65: 1822-9. (Pubitemid 40478610)
29. Han C, Michalopoulos GK, Wu T,. Prostaglandin E2 receptor EP1 transactivates EGFR/MET receptor tyrosine kinases and enhances invasiveness in human hepatocellular carcinoma cells. J Cell Physiol 2006; 207: 261-70.