-
1
-
-
0034595096
-
Estrogen receptors: How do they control reproductive and nonreproductive functions?
-
Muramatsu M, Inoue S. Estrogen receptors: how do they control reproductive and nonreproductive functions? Biochem Biophys Res Commun 2000;270:1-10
-
(2000)
Biochem Biophys Res Commun
, vol.270
, pp. 1-10
-
-
Muramatsu, M.1
Inoue, S.2
-
3
-
-
78650446029
-
Estrogen receptors: Therapies targeted to receptor subtypes
-
Nilsson S, Gustafsson JA. Estrogen receptors: therapies targeted to receptor subtypes. Clin Pharmacol Ther 2011;89:44-55.
-
(2011)
Clin Pharmacol Ther
, vol.89
, pp. 44-55
-
-
Nilsson, S.1
Gustafsson, J.A.2
-
4
-
-
0026343481
-
Transcription activation by estrogen and progesterone receptors
-
Gronemeyer H. Transcription activation by estrogen and progesterone receptors. Annu Rev Genet 1991;25:89-123.
-
(1991)
Annu Rev Genet
, vol.25
, pp. 89-123
-
-
Gronemeyer, H.1
-
5
-
-
0033054115
-
The structure of the nuclear hormone receptors
-
Kumar R, Thompson EB. The structure of the nuclear hormone receptors. Steroids 1999;64:310-9.
-
(1999)
Steroids
, vol.64
, pp. 310-319
-
-
Kumar, R.1
Thompson, E.B.2
-
6
-
-
0031611355
-
Transcriptional activation by oestrogen receptors
-
Parker MG. Transcriptional activation by oestrogen receptors. Biochem Soc Symp 1998;63:45-50.
-
(1998)
Biochem Soc Symp
, vol.63
, pp. 45-50
-
-
Parker, M.G.1
-
7
-
-
1442351143
-
Coregulator function: A key to understanding tissue specificity of selective receptor modulators
-
Smith CL, O'Malley BW. Coregulator function: a key to understanding tissue specificity of selective receptor modulators. Endocr Rev 2004;25:45-71.
-
(2004)
Endocr Rev
, vol.25
, pp. 45-71
-
-
Smith, C.L.1
O'Malley, B.W.2
-
9
-
-
70849093259
-
Regulation of estrogen receptor beta activity and implications in health and disease
-
Swedenborg E, Power KA, Cai W, et al. Regulation of estrogen receptor beta activity and implications in health and disease. Cell Mol Life Sci 2009;66:3873-94.
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 3873-3894
-
-
Swedenborg, E.1
Power, K.A.2
Cai, W.3
-
10
-
-
72549085551
-
Genomic actions of estrogen receptor alpha: What are the targets and how are they regulated?
-
Welboren WJ, Sweep FC, Span PN, Stunnenberg HG. Genomic actions of estrogen receptor alpha: what are the targets and how are they regulated? Endocr Relat Cancer 2009;16:1073-89
-
(2009)
Endocr Relat Cancer
, vol.16
, pp. 1073-1089
-
-
Welboren, W.J.1
Sweep, F.C.2
Span, P.N.3
Stunnenberg, H.G.4
-
11
-
-
0030733906
-
Human estrogen receptor beta-gene structure, chromosomal localization, and expression pattern
-
Enmark E, Pelto-Huikko M, Grandien K, et al. Human estrogen receptor beta-gene structure, chromosomal localization, and expression pattern. J Clin Endocrinol Metab 1997;82:4258-65.
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 4258-4265
-
-
Enmark, E.1
Pelto-Huikko, M.2
Grandien, K.3
-
12
-
-
0031092770
-
A new actor in the estrogen receptor drama-enter ER-beta
-
Katzenellenbogen BS, Korach KS. A new actor in the estrogen receptor drama-enter ER-beta. Endocrinology 1997;138:861-2.
-
(1997)
Endocrinology
, vol.138
, pp. 861-862
-
-
Katzenellenbogen, B.S.1
Korach, K.S.2
-
13
-
-
0031039888
-
Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta
-
Kuiper GG, Carlsson B, Grandien K, et al. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta. Endocrinology 1997;138: 863-70.
-
(1997)
Endocrinology
, vol.138
, pp. 863-870
-
-
Kuiper, G.G.1
Carlsson, B.2
Grandien, K.3
-
14
-
-
0030579801
-
Cloning of a novel receptor expressed in rat prostate and ovary
-
Kuiper GG, Enmark E, Pelto-Huikko M, et al. Cloning of a novel receptor expressed in rat prostate and ovary. Proc Natl Acad Sci U S A 1996;93:5925-30.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 5925-5930
-
-
Kuiper, G.G.1
Enmark, E.2
Pelto-Huikko, M.3
-
15
-
-
0030593681
-
ER beta: Identification and characterization of a novel human estrogen receptor
-
Mosselman S, Polman J, Dijkema R. ER beta: identification and characterization of a novel human estrogen receptor. FEBS Lett 1996;392:49-53.
-
(1996)
FEBS Lett
, vol.392
, pp. 49-53
-
-
Mosselman, S.1
Polman, J.2
Dijkema, R.3
-
16
-
-
0029618368
-
Steroid hormone receptors: Many actors in search of a plot
-
Beato M, Herrlich P, Schutz G. Steroid hormone receptors: many actors in search of a plot. Cell 1995;83:851-7.
-
(1995)
Cell
, vol.83
, pp. 851-857
-
-
Beato, M.1
Herrlich, P.2
Schutz, G.3
-
17
-
-
0024545638
-
Gene regulation by steroid hormones
-
Beato M. Gene regulation by steroid hormones. Cell 1989;56: 335-44.
-
(1989)
Cell
, vol.56
, pp. 335-344
-
-
Beato, M.1
-
18
-
-
0024317270
-
The human estrogen receptor has two independent nonacidic transcriptional activation functions
-
Tora L, White J, Brou C, et al. The human estrogen receptor has two independent nonacidic transcriptional activation functions. Cell 1989;59:477-87.
-
(1989)
Cell
, vol.59
, pp. 477-487
-
-
Tora, L.1
White, J.2
Brou, C.3
-
19
-
-
0025062215
-
Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen
-
Berry M, Metzger D, Chambon P. Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen. EMBO J 1990;9:2811-8.
-
(1990)
EMBO J
, vol.9
, pp. 2811-2818
-
-
Berry, M.1
Metzger, D.2
Chambon, P.3
-
20
-
-
0029058152
-
The carboxy-terminal F domain of the human estrogen receptor: Role in the transcriptional activity of the receptor and the effectiveness of antiestrogens as estrogen antagonists
-
Montano MM, Muller V, Trobaugh A, Katzenellenbogen BS. The carboxy-terminal F domain of the human estrogen receptor: role in the transcriptional activity of the receptor and the effectiveness of antiestrogens as estrogen antagonists. Mol Endocrinol 1995; 9:814-25.
-
(1995)
Mol Endocrinol
, vol.9
, pp. 814-825
-
-
Montano, M.M.1
Muller, V.2
Trobaugh, A.3
Katzenellenbogen, B.S.4
-
21
-
-
34247889975
-
Identification of regions within the F domain of the human estrogen receptor alpha that are important for modulating transactivation and protein-protein interactions
-
Koide A, Zhao C, Naganuma M, et al. Identification of regions within the F domain of the human estrogen receptor alpha that are important for modulating transactivation and protein-protein interactions. Mol Endocrinol 2007;21:829-42.
-
(2007)
Mol Endocrinol
, vol.21
, pp. 829-842
-
-
Koide, A.1
Zhao, C.2
Naganuma, M.3
-
22
-
-
54849420674
-
The F-domain of estrogen receptor-alpha inhibits ligand induced receptor dimerization
-
Yang J, Singleton DW, Shaughnessy EA, Khan SA. The F-domain of estrogen receptor-alpha inhibits ligand induced receptor dimerization. Mol Cell Endocrinol 2008;295:94-100.
-
(2008)
Mol Cell Endocrinol
, vol.295
, pp. 94-100
-
-
Yang, J.1
Singleton, D.W.2
Shaughnessy, E.A.3
Khan, S.A.4
-
23
-
-
0025223160
-
Solution structure of the DNA-binding domain of the oestrogen receptor
-
Schwabe JW, Neuhaus D, Rhodes D. Solution structure of the DNA-binding domain of the oestrogen receptor. Nature 1990;348: 458-61.
-
(1990)
Nature
, vol.348
, pp. 458-461
-
-
Schwabe, J.W.1
Neuhaus, D.2
Rhodes, D.3
-
24
-
-
0027365669
-
The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: How receptors discriminate between their response elements
-
Schwabe JW, Chapman L, Finch JT, Rhodes D. The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements. Cell 1993;75:567-78.
-
(1993)
Cell
, vol.75
, pp. 567-578
-
-
Schwabe, J.W.1
Chapman, L.2
Finch, J.T.3
Rhodes, D.4
-
25
-
-
0030667676
-
Molecular basis of agonism and antagonism in the oestrogen receptor
-
Brzozowski AM, Pike AC, Dauter Z, et al. Molecular basis of agonism and antagonism in the oestrogen receptor. Nature 1997;389: 753-8.
-
(1997)
Nature
, vol.389
, pp. 753-758
-
-
Brzozowski, A.M.1
Pike, A.C.2
Dauter, Z.3
-
26
-
-
0033198735
-
Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist
-
Pike AC, Brzozowski AM, Hubbard RE, et al. Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist. EMBO J 1999;18:4608-18.
-
(1999)
EMBO J
, vol.18
, pp. 4608-4618
-
-
Pike, A.C.1
Brzozowski, A.M.2
Hubbard, R.E.3
-
27
-
-
14844353602
-
Delineation of a unique protein-protein interaction site on the surface of the estrogen receptor
-
Kong EH, Heldring N, Gustafsson JA, et al. Delineation of a unique protein-protein interaction site on the surface of the estrogen receptor. Proc Natl Acad Sci U S A 2005;102:3593-8.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 3593-3598
-
-
Kong, E.H.1
Heldring, N.2
Gustafsson, J.A.3
-
28
-
-
0032568527
-
Crystallographic comparison of the estrogen and progesterone receptor's ligand binding domains
-
Tanenbaum DM,Wang Y, Williams SP, Sigler PB. Crystallographic comparison of the estrogen and progesterone receptor's ligand binding domains. Proc Natl Acad Sci U S A 1998;95:5998-6003.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 5998-6003
-
-
Tanenbaum, D.M.1
Wang, Y.2
Williams, S.P.3
Sigler, P.B.4
-
29
-
-
33847114057
-
Conformational dynamics of the estrogen receptor alpha: Molecular dynamics simulations of the influence of binding site structure on protein dynamics
-
Celik L, Lund JD, Schiott B. Conformational dynamics of the estrogen receptor alpha: molecular dynamics simulations of the influence of binding site structure on protein dynamics. Biochemistry 2007;46:1743-58.
-
(2007)
Biochemistry
, vol.46
, pp. 1743-1758
-
-
Celik, L.1
Lund, J.D.2
Schiott, B.3
-
30
-
-
0031059270
-
The estradiol pharmacophore: Ligand structure-estrogen receptor binding affinity relationships and a model for the receptor binding site
-
Anstead GM, Carlson KE, Katzenellenbogen JA. The estradiol pharmacophore: ligand structure-estrogen receptor binding affinity relationships and a model for the receptor binding site. Steroids 1997;62:268-303.
-
(1997)
Steroids
, vol.62
, pp. 268-303
-
-
Anstead, G.M.1
Carlson, K.E.2
Katzenellenbogen, J.A.3
-
31
-
-
0032446607
-
The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen
-
Shiau AK, Barstad D, Loria PM, et al. The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen. Cell 1998;95:927-37.
-
(1998)
Cell
, vol.95
, pp. 927-937
-
-
Shiau, A.K.1
Barstad, D.2
Loria, P.M.3
-
32
-
-
0034735859
-
Molecular mechanisms of estrogen action: Selective ligands and receptor pharmacology
-
Katzenellenbogen BS, Choi I, Delage-Mourroux R, et al. Molecular mechanisms of estrogen action: selective ligands and receptor pharmacology. J Steroid Biochem Mol Biol 2000;74:279-85.
-
(2000)
J Steroid Biochem Mol Biol
, vol.74
, pp. 279-285
-
-
Katzenellenbogen, B.S.1
Choi, I.2
Delage-Mourroux, R.3
-
33
-
-
0004752110
-
Novel ligands that function as selective estrogens or antiestrogens for estrogen receptor-alpha or estrogen receptor-beta
-
Sun J, Meyers MJ, Fink BE, et al. Novel ligands that function as selective estrogens or antiestrogens for estrogen receptor-alpha or estrogen receptor-beta. Endocrinology 1999;140:800-4.
-
(1999)
Endocrinology
, vol.140
, pp. 800-804
-
-
Sun, J.1
Meyers, M.J.2
Fink, B.E.3
-
34
-
-
0038149156
-
ERbeta ligands. Part 1: The discovery of ERbeta selective ligands which embrace the 4-hydroxy-biphenyl template
-
Edsall Jr RJ, Harris HA, Manas ES, Mewshaw RE. ERbeta ligands. Part 1: the discovery of ERbeta selective ligands which embrace the 4-hydroxy-biphenyl template. Bioorg Med Chem 2003;11:3457-74.
-
(2003)
Bioorg Med Chem
, vol.11
, pp. 3457-3474
-
-
Edsall Jr., R.J.1
Harris, H.A.2
Manas, E.S.3
Mewshaw, R.E.4
-
35
-
-
33646371740
-
Molecular mechanisms of oestrogen and SERMs in endometrial carcinogenesis
-
Shang Y. Molecular mechanisms of oestrogen and SERMs in endometrial carcinogenesis. Nat Rev Cancer 2006;6:360-8.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 360-368
-
-
Shang, Y.1
-
36
-
-
0035824562
-
The N-terminal regions of estrogen receptor alpha and beta are unstructured in vitro and show different TBP binding properties
-
Warnmark A, Wikstrom A,Wright AP, et al. The N-terminal regions of estrogen receptor alpha and beta are unstructured in vitro and show different TBP binding properties. J Biol Chem 2001;276: 45939-44.
-
(2001)
J Biol Chem
, vol.276
, pp. 45939-45944
-
-
Warnmark, A.1
Wikstrom, A.2
Wright, A.P.3
-
37
-
-
0035947672
-
The conformation of the glucocorticoid receptor af1/tau1 domain induced by osmolyte binds co-regulatory proteins
-
Kumar R, Lee JC, Bolen DW, Thompson EB. The conformation of the glucocorticoid receptor af1/tau1 domain induced by osmolyte binds co-regulatory proteins. J Biol Chem 2001;276: 18146-52.
-
(2001)
J Biol Chem
, vol.276
, pp. 18146-18152
-
-
Kumar, R.1
Lee, J.C.2
Bolen, D.W.3
Thompson, E.B.4
-
38
-
-
0037245786
-
Transactivation functions of the N-terminal domains of nuclear hormone receptors: Protein folding and coactivator interactions
-
Kumar R, Thompson EB. Transactivation functions of the N-terminal domains of nuclear hormone receptors: protein folding and coactivator interactions. Mol Endocrinol 2003;17:1-10.
-
(2003)
Mol Endocrinol
, vol.17
, pp. 1-10
-
-
Kumar, R.1
Thompson, E.B.2
-
39
-
-
0031835842
-
Selective oestrogen receptor modulators: Potential therapeutic applications
-
Compston JE. Selective oestrogen receptor modulators: potential therapeutic applications. Clin Endocrinol (Oxf) 1998;48:389-91.
-
(1998)
Clin Endocrinol (Oxf)
, vol.48
, pp. 389-391
-
-
Compston, J.E.1
-
40
-
-
0032134252
-
Therapeutic potential of selective estrogen receptor modulators
-
Gustafsson JA. Therapeutic potential of selective estrogen receptor modulators. Curr Opin Chem Biol 1998;2:508-11.
-
(1998)
Curr Opin Chem Biol
, vol.2
, pp. 508-511
-
-
Gustafsson, J.A.1
-
41
-
-
0032538434
-
A transcriptional coactivator, steroid receptor coactivator-3, selectively augments steroid receptor transcriptional activity
-
Suen CS, Berrodin TJ, Mastroeni R, et al. A transcriptional coactivator, steroid receptor coactivator-3, selectively augments steroid receptor transcriptional activity. J Biol Chem 1998;273: 27645-53.
-
(1998)
J Biol Chem
, vol.273
, pp. 27645-27653
-
-
Suen, C.S.1
Berrodin, T.J.2
Mastroeni, R.3
-
42
-
-
0033120030
-
Ligand-independent recruitment of SRC-1 to estrogen receptor beta through phosphorylation of activation function AF-1
-
Tremblay A, Tremblay GB, Labrie F, Giguere V. Ligand-independent recruitment of SRC-1 to estrogen receptor beta through phosphorylation of activation function AF-1. Mol Cell 1999;3: 513-9.
-
(1999)
Mol Cell
, vol.3
, pp. 513-519
-
-
Tremblay, A.1
Tremblay, G.B.2
Labrie, F.3
Giguere, V.4
-
43
-
-
0030797902
-
AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer
-
Anzick SL, Kononen J, Walker RL, et al. AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer. Science 1997; 277:965-8.
-
(1997)
Science
, vol.277
, pp. 965-968
-
-
Anzick, S.L.1
Kononen, J.2
Walker, R.L.3
-
44
-
-
13044292640
-
Generation and reproductive phenotypes of mice lacking estrogen receptor beta
-
Krege JH, Hodgin JB, Couse JF, et al. Generation and reproductive phenotypes of mice lacking estrogen receptor beta. Proc Natl Acad Sci U S A 1998;95:15677-82.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 15677-15682
-
-
Krege, J.H.1
Hodgin, J.B.2
Couse, J.F.3
-
46
-
-
80053562371
-
Development of subtypeselective oestrogen receptor-based therapeutics
-
Nilsson S, Koehler KF, Gustafsson JA. Development of subtypeselective oestrogen receptor-based therapeutics. Nat Rev Drug Discov 2011;10:778-92.
-
(2011)
Nat Rev Drug Discov
, vol.10
, pp. 778-792
-
-
Nilsson, S.1
Koehler, K.F.2
Gustafsson, J.A.3
-
48
-
-
0032924732
-
Mice, estrogen, and postmenopausal osteoporosis
-
Turner RT. Mice, estrogen, and postmenopausal osteoporosis. J Bone Miner Res 1999;14:187-91.
-
(1999)
J Bone Miner Res
, vol.14
, pp. 187-191
-
-
Turner, R.T.1
-
49
-
-
0025457129
-
Differential effects of androgens on cortical bone histomorphometry in gonadectomized male and female rats
-
Turner RT, Wakley GK, Hannon KS. Differential effects of androgens on cortical bone histomorphometry in gonadectomized male and female rats. J Orthop Res 1990;8:612-7.
-
(1990)
J Orthop Res
, vol.8
, pp. 612-617
-
-
Turner, R.T.1
Wakley, G.K.2
Hannon, K.S.3
-
50
-
-
0030954869
-
Expression of estrogen receptor beta in rat bone
-
Onoe Y, Miyaura C, Ohta H, et al. Expression of estrogen receptor beta in rat bone. Endocrinology 1997;138:4509-12.
-
(1997)
Endocrinology
, vol.138
, pp. 4509-4512
-
-
Onoe, Y.1
Miyaura, C.2
Ohta, H.3
-
51
-
-
0033054576
-
Expression of estrogen receptor-alpha in cells of the osteoclastic lineage
-
Oreffo RO, Kusec V, Virdi AS, et al. Expression of estrogen receptor-alpha in cells of the osteoclastic lineage. Histochem Cell Biol 1999;111:125-33.
-
(1999)
Histochem Cell Biol
, vol.111
, pp. 125-133
-
-
Oreffo, R.O.1
Kusec, V.2
Virdi, A.S.3
-
52
-
-
0031728255
-
Localization of estrogen receptor-alpha in human and rabbit skeletal tissues
-
Kusec V, Virdi AS, Prince R, Triffitt JT. Localization of estrogen receptor-alpha in human and rabbit skeletal tissues. J Clin Endocrinol Metab 1998;83:2421-8.
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 2421-2428
-
-
Kusec, V.1
Virdi, A.S.2
Prince, R.3
Triffitt, J.T.4
-
53
-
-
0032932703
-
Demonstration of estrogen receptor-beta immunoreactivity in human growth plate cartilage
-
Nilsson LO, Boman A, Savendahl L, et al. Demonstration of estrogen receptor-beta immunoreactivity in human growth plate cartilage. J Clin Endocrinol Metab 1999;84:370-3.
-
(1999)
J Clin Endocrinol Metab
, vol.84
, pp. 370-373
-
-
Nilsson, L.O.1
Boman, A.2
Savendahl, L.3
-
54
-
-
0033028733
-
Expression and localization of estrogen receptor-beta in murine and human bone
-
Vidal O, Kindblom LG, Ohlsson C. Expression and localization of estrogen receptor-beta in murine and human bone. J Bone Miner Res 1999;14:923-9.
-
(1999)
J Bone Miner Res
, vol.14
, pp. 923-929
-
-
Vidal, O.1
Kindblom, L.G.2
Ohlsson, C.3
-
55
-
-
79953005347
-
Small molecule inhibitors as probes for estrogen and androgen receptor action
-
Shapiro DJ, Mao C, Cherian MT. Small molecule inhibitors as probes for estrogen and androgen receptor action. J Biol Chem 2011;286:4043-8.
-
(2011)
J Biol Chem
, vol.286
, pp. 4043-4048
-
-
Shapiro, D.J.1
Mao, C.2
Cherian, M.T.3
-
56
-
-
34548241775
-
Fulvestrant (Faslodex-) - How to make a good drug better
-
Robertson JF. Fulvestrant (Faslodex-) - How to make a good drug better. Oncologist 2007;12:774-84.
-
(2007)
Oncologist
, vol.12
, pp. 774-784
-
-
Robertson, J.F.1
-
57
-
-
84866607246
-
Nuclear receptor coregulators: Modulators of pathology and therapeutic targets
-
Lonard DM, O'Malley BW. Nuclear receptor coregulators: modulators of pathology and therapeutic targets. Nat Rev Endocrinol 2012;8:598-604.
-
(2012)
Nat Rev Endocrinol
, vol.8
, pp. 598-604
-
-
Lonard, D.M.1
O'Malley, B.W.2
-
58
-
-
80053562371
-
Development of subtypeselective oestrogen receptor-based therapeutics
-
Nilsson S, Koehler KF, Gustafsson JA. Development of subtypeselective oestrogen receptor-based therapeutics. Nat Rev Drug Discov 2011;10:778-92.
-
(2011)
Nat Rev Drug Discov
, vol.10
, pp. 778-792
-
-
Nilsson, S.1
Koehler, K.F.2
Gustafsson, J.A.3
|