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Volumn 34, Issue 1, 2014, Pages 1-5

Estrogen receptors (ERα versus ERβ): Friends or foes in human biology?

Author keywords

Coregulators; Estrogen receptor; Gene regulation; Pathology; Physiology

Indexed keywords

ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; TATA BINDING PROTEIN;

EID: 84893143351     PISSN: 10799893     EISSN: 15324281     Source Type: Journal    
DOI: 10.3109/10799893.2013.853188     Document Type: Review
Times cited : (25)

References (58)
  • 1
    • 0034595096 scopus 로고    scopus 로고
    • Estrogen receptors: How do they control reproductive and nonreproductive functions?
    • Muramatsu M, Inoue S. Estrogen receptors: how do they control reproductive and nonreproductive functions? Biochem Biophys Res Commun 2000;270:1-10
    • (2000) Biochem Biophys Res Commun , vol.270 , pp. 1-10
    • Muramatsu, M.1    Inoue, S.2
  • 3
    • 78650446029 scopus 로고    scopus 로고
    • Estrogen receptors: Therapies targeted to receptor subtypes
    • Nilsson S, Gustafsson JA. Estrogen receptors: therapies targeted to receptor subtypes. Clin Pharmacol Ther 2011;89:44-55.
    • (2011) Clin Pharmacol Ther , vol.89 , pp. 44-55
    • Nilsson, S.1    Gustafsson, J.A.2
  • 4
    • 0026343481 scopus 로고
    • Transcription activation by estrogen and progesterone receptors
    • Gronemeyer H. Transcription activation by estrogen and progesterone receptors. Annu Rev Genet 1991;25:89-123.
    • (1991) Annu Rev Genet , vol.25 , pp. 89-123
    • Gronemeyer, H.1
  • 5
    • 0033054115 scopus 로고    scopus 로고
    • The structure of the nuclear hormone receptors
    • Kumar R, Thompson EB. The structure of the nuclear hormone receptors. Steroids 1999;64:310-9.
    • (1999) Steroids , vol.64 , pp. 310-319
    • Kumar, R.1    Thompson, E.B.2
  • 6
    • 0031611355 scopus 로고    scopus 로고
    • Transcriptional activation by oestrogen receptors
    • Parker MG. Transcriptional activation by oestrogen receptors. Biochem Soc Symp 1998;63:45-50.
    • (1998) Biochem Soc Symp , vol.63 , pp. 45-50
    • Parker, M.G.1
  • 7
    • 1442351143 scopus 로고    scopus 로고
    • Coregulator function: A key to understanding tissue specificity of selective receptor modulators
    • Smith CL, O'Malley BW. Coregulator function: a key to understanding tissue specificity of selective receptor modulators. Endocr Rev 2004;25:45-71.
    • (2004) Endocr Rev , vol.25 , pp. 45-71
    • Smith, C.L.1    O'Malley, B.W.2
  • 9
    • 70849093259 scopus 로고    scopus 로고
    • Regulation of estrogen receptor beta activity and implications in health and disease
    • Swedenborg E, Power KA, Cai W, et al. Regulation of estrogen receptor beta activity and implications in health and disease. Cell Mol Life Sci 2009;66:3873-94.
    • (2009) Cell Mol Life Sci , vol.66 , pp. 3873-3894
    • Swedenborg, E.1    Power, K.A.2    Cai, W.3
  • 10
    • 72549085551 scopus 로고    scopus 로고
    • Genomic actions of estrogen receptor alpha: What are the targets and how are they regulated?
    • Welboren WJ, Sweep FC, Span PN, Stunnenberg HG. Genomic actions of estrogen receptor alpha: what are the targets and how are they regulated? Endocr Relat Cancer 2009;16:1073-89
    • (2009) Endocr Relat Cancer , vol.16 , pp. 1073-1089
    • Welboren, W.J.1    Sweep, F.C.2    Span, P.N.3    Stunnenberg, H.G.4
  • 11
    • 0030733906 scopus 로고    scopus 로고
    • Human estrogen receptor beta-gene structure, chromosomal localization, and expression pattern
    • Enmark E, Pelto-Huikko M, Grandien K, et al. Human estrogen receptor beta-gene structure, chromosomal localization, and expression pattern. J Clin Endocrinol Metab 1997;82:4258-65.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 4258-4265
    • Enmark, E.1    Pelto-Huikko, M.2    Grandien, K.3
  • 12
    • 0031092770 scopus 로고    scopus 로고
    • A new actor in the estrogen receptor drama-enter ER-beta
    • Katzenellenbogen BS, Korach KS. A new actor in the estrogen receptor drama-enter ER-beta. Endocrinology 1997;138:861-2.
    • (1997) Endocrinology , vol.138 , pp. 861-862
    • Katzenellenbogen, B.S.1    Korach, K.S.2
  • 13
    • 0031039888 scopus 로고    scopus 로고
    • Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta
    • Kuiper GG, Carlsson B, Grandien K, et al. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta. Endocrinology 1997;138: 863-70.
    • (1997) Endocrinology , vol.138 , pp. 863-870
    • Kuiper, G.G.1    Carlsson, B.2    Grandien, K.3
  • 14
    • 0030579801 scopus 로고    scopus 로고
    • Cloning of a novel receptor expressed in rat prostate and ovary
    • Kuiper GG, Enmark E, Pelto-Huikko M, et al. Cloning of a novel receptor expressed in rat prostate and ovary. Proc Natl Acad Sci U S A 1996;93:5925-30.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 5925-5930
    • Kuiper, G.G.1    Enmark, E.2    Pelto-Huikko, M.3
  • 15
    • 0030593681 scopus 로고    scopus 로고
    • ER beta: Identification and characterization of a novel human estrogen receptor
    • Mosselman S, Polman J, Dijkema R. ER beta: identification and characterization of a novel human estrogen receptor. FEBS Lett 1996;392:49-53.
    • (1996) FEBS Lett , vol.392 , pp. 49-53
    • Mosselman, S.1    Polman, J.2    Dijkema, R.3
  • 16
    • 0029618368 scopus 로고
    • Steroid hormone receptors: Many actors in search of a plot
    • Beato M, Herrlich P, Schutz G. Steroid hormone receptors: many actors in search of a plot. Cell 1995;83:851-7.
    • (1995) Cell , vol.83 , pp. 851-857
    • Beato, M.1    Herrlich, P.2    Schutz, G.3
  • 17
    • 0024545638 scopus 로고
    • Gene regulation by steroid hormones
    • Beato M. Gene regulation by steroid hormones. Cell 1989;56: 335-44.
    • (1989) Cell , vol.56 , pp. 335-344
    • Beato, M.1
  • 18
    • 0024317270 scopus 로고
    • The human estrogen receptor has two independent nonacidic transcriptional activation functions
    • Tora L, White J, Brou C, et al. The human estrogen receptor has two independent nonacidic transcriptional activation functions. Cell 1989;59:477-87.
    • (1989) Cell , vol.59 , pp. 477-487
    • Tora, L.1    White, J.2    Brou, C.3
  • 19
    • 0025062215 scopus 로고
    • Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen
    • Berry M, Metzger D, Chambon P. Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen. EMBO J 1990;9:2811-8.
    • (1990) EMBO J , vol.9 , pp. 2811-2818
    • Berry, M.1    Metzger, D.2    Chambon, P.3
  • 20
    • 0029058152 scopus 로고
    • The carboxy-terminal F domain of the human estrogen receptor: Role in the transcriptional activity of the receptor and the effectiveness of antiestrogens as estrogen antagonists
    • Montano MM, Muller V, Trobaugh A, Katzenellenbogen BS. The carboxy-terminal F domain of the human estrogen receptor: role in the transcriptional activity of the receptor and the effectiveness of antiestrogens as estrogen antagonists. Mol Endocrinol 1995; 9:814-25.
    • (1995) Mol Endocrinol , vol.9 , pp. 814-825
    • Montano, M.M.1    Muller, V.2    Trobaugh, A.3    Katzenellenbogen, B.S.4
  • 21
    • 34247889975 scopus 로고    scopus 로고
    • Identification of regions within the F domain of the human estrogen receptor alpha that are important for modulating transactivation and protein-protein interactions
    • Koide A, Zhao C, Naganuma M, et al. Identification of regions within the F domain of the human estrogen receptor alpha that are important for modulating transactivation and protein-protein interactions. Mol Endocrinol 2007;21:829-42.
    • (2007) Mol Endocrinol , vol.21 , pp. 829-842
    • Koide, A.1    Zhao, C.2    Naganuma, M.3
  • 22
    • 54849420674 scopus 로고    scopus 로고
    • The F-domain of estrogen receptor-alpha inhibits ligand induced receptor dimerization
    • Yang J, Singleton DW, Shaughnessy EA, Khan SA. The F-domain of estrogen receptor-alpha inhibits ligand induced receptor dimerization. Mol Cell Endocrinol 2008;295:94-100.
    • (2008) Mol Cell Endocrinol , vol.295 , pp. 94-100
    • Yang, J.1    Singleton, D.W.2    Shaughnessy, E.A.3    Khan, S.A.4
  • 23
    • 0025223160 scopus 로고
    • Solution structure of the DNA-binding domain of the oestrogen receptor
    • Schwabe JW, Neuhaus D, Rhodes D. Solution structure of the DNA-binding domain of the oestrogen receptor. Nature 1990;348: 458-61.
    • (1990) Nature , vol.348 , pp. 458-461
    • Schwabe, J.W.1    Neuhaus, D.2    Rhodes, D.3
  • 24
    • 0027365669 scopus 로고
    • The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: How receptors discriminate between their response elements
    • Schwabe JW, Chapman L, Finch JT, Rhodes D. The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements. Cell 1993;75:567-78.
    • (1993) Cell , vol.75 , pp. 567-578
    • Schwabe, J.W.1    Chapman, L.2    Finch, J.T.3    Rhodes, D.4
  • 25
    • 0030667676 scopus 로고    scopus 로고
    • Molecular basis of agonism and antagonism in the oestrogen receptor
    • Brzozowski AM, Pike AC, Dauter Z, et al. Molecular basis of agonism and antagonism in the oestrogen receptor. Nature 1997;389: 753-8.
    • (1997) Nature , vol.389 , pp. 753-758
    • Brzozowski, A.M.1    Pike, A.C.2    Dauter, Z.3
  • 26
    • 0033198735 scopus 로고    scopus 로고
    • Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist
    • Pike AC, Brzozowski AM, Hubbard RE, et al. Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist. EMBO J 1999;18:4608-18.
    • (1999) EMBO J , vol.18 , pp. 4608-4618
    • Pike, A.C.1    Brzozowski, A.M.2    Hubbard, R.E.3
  • 27
    • 14844353602 scopus 로고    scopus 로고
    • Delineation of a unique protein-protein interaction site on the surface of the estrogen receptor
    • Kong EH, Heldring N, Gustafsson JA, et al. Delineation of a unique protein-protein interaction site on the surface of the estrogen receptor. Proc Natl Acad Sci U S A 2005;102:3593-8.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 3593-3598
    • Kong, E.H.1    Heldring, N.2    Gustafsson, J.A.3
  • 28
    • 0032568527 scopus 로고    scopus 로고
    • Crystallographic comparison of the estrogen and progesterone receptor's ligand binding domains
    • Tanenbaum DM,Wang Y, Williams SP, Sigler PB. Crystallographic comparison of the estrogen and progesterone receptor's ligand binding domains. Proc Natl Acad Sci U S A 1998;95:5998-6003.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 5998-6003
    • Tanenbaum, D.M.1    Wang, Y.2    Williams, S.P.3    Sigler, P.B.4
  • 29
    • 33847114057 scopus 로고    scopus 로고
    • Conformational dynamics of the estrogen receptor alpha: Molecular dynamics simulations of the influence of binding site structure on protein dynamics
    • Celik L, Lund JD, Schiott B. Conformational dynamics of the estrogen receptor alpha: molecular dynamics simulations of the influence of binding site structure on protein dynamics. Biochemistry 2007;46:1743-58.
    • (2007) Biochemistry , vol.46 , pp. 1743-1758
    • Celik, L.1    Lund, J.D.2    Schiott, B.3
  • 30
    • 0031059270 scopus 로고    scopus 로고
    • The estradiol pharmacophore: Ligand structure-estrogen receptor binding affinity relationships and a model for the receptor binding site
    • Anstead GM, Carlson KE, Katzenellenbogen JA. The estradiol pharmacophore: ligand structure-estrogen receptor binding affinity relationships and a model for the receptor binding site. Steroids 1997;62:268-303.
    • (1997) Steroids , vol.62 , pp. 268-303
    • Anstead, G.M.1    Carlson, K.E.2    Katzenellenbogen, J.A.3
  • 31
    • 0032446607 scopus 로고    scopus 로고
    • The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen
    • Shiau AK, Barstad D, Loria PM, et al. The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen. Cell 1998;95:927-37.
    • (1998) Cell , vol.95 , pp. 927-937
    • Shiau, A.K.1    Barstad, D.2    Loria, P.M.3
  • 32
    • 0034735859 scopus 로고    scopus 로고
    • Molecular mechanisms of estrogen action: Selective ligands and receptor pharmacology
    • Katzenellenbogen BS, Choi I, Delage-Mourroux R, et al. Molecular mechanisms of estrogen action: selective ligands and receptor pharmacology. J Steroid Biochem Mol Biol 2000;74:279-85.
    • (2000) J Steroid Biochem Mol Biol , vol.74 , pp. 279-285
    • Katzenellenbogen, B.S.1    Choi, I.2    Delage-Mourroux, R.3
  • 33
    • 0004752110 scopus 로고    scopus 로고
    • Novel ligands that function as selective estrogens or antiestrogens for estrogen receptor-alpha or estrogen receptor-beta
    • Sun J, Meyers MJ, Fink BE, et al. Novel ligands that function as selective estrogens or antiestrogens for estrogen receptor-alpha or estrogen receptor-beta. Endocrinology 1999;140:800-4.
    • (1999) Endocrinology , vol.140 , pp. 800-804
    • Sun, J.1    Meyers, M.J.2    Fink, B.E.3
  • 34
    • 0038149156 scopus 로고    scopus 로고
    • ERbeta ligands. Part 1: The discovery of ERbeta selective ligands which embrace the 4-hydroxy-biphenyl template
    • Edsall Jr RJ, Harris HA, Manas ES, Mewshaw RE. ERbeta ligands. Part 1: the discovery of ERbeta selective ligands which embrace the 4-hydroxy-biphenyl template. Bioorg Med Chem 2003;11:3457-74.
    • (2003) Bioorg Med Chem , vol.11 , pp. 3457-3474
    • Edsall Jr., R.J.1    Harris, H.A.2    Manas, E.S.3    Mewshaw, R.E.4
  • 35
    • 33646371740 scopus 로고    scopus 로고
    • Molecular mechanisms of oestrogen and SERMs in endometrial carcinogenesis
    • Shang Y. Molecular mechanisms of oestrogen and SERMs in endometrial carcinogenesis. Nat Rev Cancer 2006;6:360-8.
    • (2006) Nat Rev Cancer , vol.6 , pp. 360-368
    • Shang, Y.1
  • 36
    • 0035824562 scopus 로고    scopus 로고
    • The N-terminal regions of estrogen receptor alpha and beta are unstructured in vitro and show different TBP binding properties
    • Warnmark A, Wikstrom A,Wright AP, et al. The N-terminal regions of estrogen receptor alpha and beta are unstructured in vitro and show different TBP binding properties. J Biol Chem 2001;276: 45939-44.
    • (2001) J Biol Chem , vol.276 , pp. 45939-45944
    • Warnmark, A.1    Wikstrom, A.2    Wright, A.P.3
  • 37
    • 0035947672 scopus 로고    scopus 로고
    • The conformation of the glucocorticoid receptor af1/tau1 domain induced by osmolyte binds co-regulatory proteins
    • Kumar R, Lee JC, Bolen DW, Thompson EB. The conformation of the glucocorticoid receptor af1/tau1 domain induced by osmolyte binds co-regulatory proteins. J Biol Chem 2001;276: 18146-52.
    • (2001) J Biol Chem , vol.276 , pp. 18146-18152
    • Kumar, R.1    Lee, J.C.2    Bolen, D.W.3    Thompson, E.B.4
  • 38
    • 0037245786 scopus 로고    scopus 로고
    • Transactivation functions of the N-terminal domains of nuclear hormone receptors: Protein folding and coactivator interactions
    • Kumar R, Thompson EB. Transactivation functions of the N-terminal domains of nuclear hormone receptors: protein folding and coactivator interactions. Mol Endocrinol 2003;17:1-10.
    • (2003) Mol Endocrinol , vol.17 , pp. 1-10
    • Kumar, R.1    Thompson, E.B.2
  • 39
    • 0031835842 scopus 로고    scopus 로고
    • Selective oestrogen receptor modulators: Potential therapeutic applications
    • Compston JE. Selective oestrogen receptor modulators: potential therapeutic applications. Clin Endocrinol (Oxf) 1998;48:389-91.
    • (1998) Clin Endocrinol (Oxf) , vol.48 , pp. 389-391
    • Compston, J.E.1
  • 40
    • 0032134252 scopus 로고    scopus 로고
    • Therapeutic potential of selective estrogen receptor modulators
    • Gustafsson JA. Therapeutic potential of selective estrogen receptor modulators. Curr Opin Chem Biol 1998;2:508-11.
    • (1998) Curr Opin Chem Biol , vol.2 , pp. 508-511
    • Gustafsson, J.A.1
  • 41
    • 0032538434 scopus 로고    scopus 로고
    • A transcriptional coactivator, steroid receptor coactivator-3, selectively augments steroid receptor transcriptional activity
    • Suen CS, Berrodin TJ, Mastroeni R, et al. A transcriptional coactivator, steroid receptor coactivator-3, selectively augments steroid receptor transcriptional activity. J Biol Chem 1998;273: 27645-53.
    • (1998) J Biol Chem , vol.273 , pp. 27645-27653
    • Suen, C.S.1    Berrodin, T.J.2    Mastroeni, R.3
  • 42
    • 0033120030 scopus 로고    scopus 로고
    • Ligand-independent recruitment of SRC-1 to estrogen receptor beta through phosphorylation of activation function AF-1
    • Tremblay A, Tremblay GB, Labrie F, Giguere V. Ligand-independent recruitment of SRC-1 to estrogen receptor beta through phosphorylation of activation function AF-1. Mol Cell 1999;3: 513-9.
    • (1999) Mol Cell , vol.3 , pp. 513-519
    • Tremblay, A.1    Tremblay, G.B.2    Labrie, F.3    Giguere, V.4
  • 43
    • 0030797902 scopus 로고    scopus 로고
    • AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer
    • Anzick SL, Kononen J, Walker RL, et al. AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer. Science 1997; 277:965-8.
    • (1997) Science , vol.277 , pp. 965-968
    • Anzick, S.L.1    Kononen, J.2    Walker, R.L.3
  • 44
    • 13044292640 scopus 로고    scopus 로고
    • Generation and reproductive phenotypes of mice lacking estrogen receptor beta
    • Krege JH, Hodgin JB, Couse JF, et al. Generation and reproductive phenotypes of mice lacking estrogen receptor beta. Proc Natl Acad Sci U S A 1998;95:15677-82.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 15677-15682
    • Krege, J.H.1    Hodgin, J.B.2    Couse, J.F.3
  • 46
    • 80053562371 scopus 로고    scopus 로고
    • Development of subtypeselective oestrogen receptor-based therapeutics
    • Nilsson S, Koehler KF, Gustafsson JA. Development of subtypeselective oestrogen receptor-based therapeutics. Nat Rev Drug Discov 2011;10:778-92.
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 778-792
    • Nilsson, S.1    Koehler, K.F.2    Gustafsson, J.A.3
  • 47
  • 48
    • 0032924732 scopus 로고    scopus 로고
    • Mice, estrogen, and postmenopausal osteoporosis
    • Turner RT. Mice, estrogen, and postmenopausal osteoporosis. J Bone Miner Res 1999;14:187-91.
    • (1999) J Bone Miner Res , vol.14 , pp. 187-191
    • Turner, R.T.1
  • 49
    • 0025457129 scopus 로고
    • Differential effects of androgens on cortical bone histomorphometry in gonadectomized male and female rats
    • Turner RT, Wakley GK, Hannon KS. Differential effects of androgens on cortical bone histomorphometry in gonadectomized male and female rats. J Orthop Res 1990;8:612-7.
    • (1990) J Orthop Res , vol.8 , pp. 612-617
    • Turner, R.T.1    Wakley, G.K.2    Hannon, K.S.3
  • 50
    • 0030954869 scopus 로고    scopus 로고
    • Expression of estrogen receptor beta in rat bone
    • Onoe Y, Miyaura C, Ohta H, et al. Expression of estrogen receptor beta in rat bone. Endocrinology 1997;138:4509-12.
    • (1997) Endocrinology , vol.138 , pp. 4509-4512
    • Onoe, Y.1    Miyaura, C.2    Ohta, H.3
  • 51
    • 0033054576 scopus 로고    scopus 로고
    • Expression of estrogen receptor-alpha in cells of the osteoclastic lineage
    • Oreffo RO, Kusec V, Virdi AS, et al. Expression of estrogen receptor-alpha in cells of the osteoclastic lineage. Histochem Cell Biol 1999;111:125-33.
    • (1999) Histochem Cell Biol , vol.111 , pp. 125-133
    • Oreffo, R.O.1    Kusec, V.2    Virdi, A.S.3
  • 52
    • 0031728255 scopus 로고    scopus 로고
    • Localization of estrogen receptor-alpha in human and rabbit skeletal tissues
    • Kusec V, Virdi AS, Prince R, Triffitt JT. Localization of estrogen receptor-alpha in human and rabbit skeletal tissues. J Clin Endocrinol Metab 1998;83:2421-8.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 2421-2428
    • Kusec, V.1    Virdi, A.S.2    Prince, R.3    Triffitt, J.T.4
  • 53
    • 0032932703 scopus 로고    scopus 로고
    • Demonstration of estrogen receptor-beta immunoreactivity in human growth plate cartilage
    • Nilsson LO, Boman A, Savendahl L, et al. Demonstration of estrogen receptor-beta immunoreactivity in human growth plate cartilage. J Clin Endocrinol Metab 1999;84:370-3.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 370-373
    • Nilsson, L.O.1    Boman, A.2    Savendahl, L.3
  • 54
    • 0033028733 scopus 로고    scopus 로고
    • Expression and localization of estrogen receptor-beta in murine and human bone
    • Vidal O, Kindblom LG, Ohlsson C. Expression and localization of estrogen receptor-beta in murine and human bone. J Bone Miner Res 1999;14:923-9.
    • (1999) J Bone Miner Res , vol.14 , pp. 923-929
    • Vidal, O.1    Kindblom, L.G.2    Ohlsson, C.3
  • 55
    • 79953005347 scopus 로고    scopus 로고
    • Small molecule inhibitors as probes for estrogen and androgen receptor action
    • Shapiro DJ, Mao C, Cherian MT. Small molecule inhibitors as probes for estrogen and androgen receptor action. J Biol Chem 2011;286:4043-8.
    • (2011) J Biol Chem , vol.286 , pp. 4043-4048
    • Shapiro, D.J.1    Mao, C.2    Cherian, M.T.3
  • 56
    • 34548241775 scopus 로고    scopus 로고
    • Fulvestrant (Faslodex-) - How to make a good drug better
    • Robertson JF. Fulvestrant (Faslodex-) - How to make a good drug better. Oncologist 2007;12:774-84.
    • (2007) Oncologist , vol.12 , pp. 774-784
    • Robertson, J.F.1
  • 57
    • 84866607246 scopus 로고    scopus 로고
    • Nuclear receptor coregulators: Modulators of pathology and therapeutic targets
    • Lonard DM, O'Malley BW. Nuclear receptor coregulators: modulators of pathology and therapeutic targets. Nat Rev Endocrinol 2012;8:598-604.
    • (2012) Nat Rev Endocrinol , vol.8 , pp. 598-604
    • Lonard, D.M.1    O'Malley, B.W.2
  • 58
    • 80053562371 scopus 로고    scopus 로고
    • Development of subtypeselective oestrogen receptor-based therapeutics
    • Nilsson S, Koehler KF, Gustafsson JA. Development of subtypeselective oestrogen receptor-based therapeutics. Nat Rev Drug Discov 2011;10:778-92.
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 778-792
    • Nilsson, S.1    Koehler, K.F.2    Gustafsson, J.A.3


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