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Volumn 8, Issue 2, 2014, Pages 185-195

Hepatitis B surface antigen quantification in chronic hepatitis B and its clinical utility

Author keywords

chronic hepatitis B; hbsag; Hbv; Hbv Dna; inactive carriers; interferon; natural course . Nucleos(t)ide analogs; treatment

Indexed keywords

ADEFOVIR; ENTECAVIR; HEPATITIS B SURFACE ANTIGEN; LAMIVUDINE; NUCLEOSIDE DERIVATIVE; NUCLEOTIDE DERIVATIVE; PEGINTERFERON; RECOMBINANT ALPHA INTERFERON; TELBIVUDINE; TENOFOVIR;

EID: 84893096212     PISSN: 17474124     EISSN: 17474132     Source Type: Journal    
DOI: 10.1586/17474124.2014.876362     Document Type: Review
Times cited : (15)

References (105)
  • 1
    • 77957338379 scopus 로고    scopus 로고
    • Diagnostic markers of chronic hepatitis B infection and disease
    • Bonino F, Piratvisuth T, Brunetto MR, Liaw YF. Diagnostic markers of chronic hepatitis B infection and disease. Antivir Ther 2010;15(Suppl 3):35-44
    • (2010) Antivir Ther , vol.15 , Issue.SUPPL. 3 , pp. 35-44
    • Bonino, F.1    Piratvisuth, T.2    Brunetto, M.R.3    Liaw, Y.F.4
  • 2
    • 0017107072 scopus 로고
    • Hepatitis b antigen-Associated deoxyribonucleic acid polymerase activity and e antigen/anti-e system
    • Imai M, Tachibana FC, Moritsugu Y, et al. Hepatitis B antigen-Associated deoxyribonucleic acid polymerase activity and e antigen/anti-e system. Infect Immun 1976;14(3):631-5
    • (1976) Infect Immun , vol.14 , Issue.3 , pp. 631-635
    • Imai, M.1    Tachibana, F.C.2    Moritsugu, Y.3
  • 3
    • 0017329452 scopus 로고
    • The e antigen and vertical transmission of hepatitis B surface antigen
    • Beasley RP, Trepo C, Stevens CE, Szmuness W. The e antigen and vertical transmission of hepatitis B surface antigen. Am J Epidemiol 1977;105(2):94-8
    • (1977) Am J Epidemiol , vol.105 , Issue.2 , pp. 94-98
    • Beasley, R.P.1    Trepo, C.2    Stevens, C.E.3    Szmuness, W.4
  • 4
    • 0017350361 scopus 로고
    • Hepatitis and hepatitis B-Antigen in Greenland. II: Occurrence and interrelation of hepatitis B associated surface, core, and e antigen-Antibody systems in a highly endemic area
    • Skinhoj P. Hepatitis and hepatitis B-Antigen in Greenland. II: occurrence and interrelation of hepatitis B associated surface, core, and e antigen-Antibody systems in a highly endemic area. Am J Epidemiol 1977;105(2):99-106
    • (1977) Am J Epidemiol , vol.105 , Issue.2 , pp. 99-106
    • Skinhoj, P.1
  • 5
    • 0015852116 scopus 로고
    • Radioimmunoassay of hepatitis B virus-Associated (Australia) antigen employing 125 I-Antibody
    • Overby LR, Miller JP, Smith ID, et al. Radioimmunoassay of hepatitis B virus-Associated (Australia) antigen employing 125 I-Antibody. Vox Sang 1973; 24(Suppl):102-13
    • (1973) Vox Sang , vol.24 , Issue.SUPPL. , pp. 102-113
    • Overby, L.R.1    Miller, J.P.2    Smith, I.D.3
  • 6
    • 0001765014 scopus 로고
    • Hepatitis B e antigen negative chronic hepatitis B: From clinical recognition to pathogenesis and treatment
    • Hadziyannnis S. Hepatitis B e antigen negative chronic hepatitis B: from clinical recognition to pathogenesis and treatment. Vial Hepatitis Reviews 1995;1(1):7-36
    • (1995) Vial Hepatitis Reviews , vol.1 , Issue.1 , pp. 7-36
    • Hadziyannnis, S.1
  • 8
    • 0021740847 scopus 로고
    • Determination of hepatitis B virus DNA in serum by molecular hybridization
    • Shimizu Y, Ida S, Matsukura T, Yuasa T. Determination of hepatitis B virus DNA in serum by molecular hybridization. Microbiol Immunol 1984;28(10):1117-23
    • (1984) Microbiol Immunol , vol.28 , Issue.10 , pp. 1117-1123
    • Shimizu, Y.1    Ida, S.2    Matsukura, T.3    Yuasa, T.4
  • 9
    • 0033002424 scopus 로고    scopus 로고
    • The role of HBV DNA quantitative PCR in monitoring the response to interferon treatment in chronic hepatitis B virus infection
    • Nagata I, Colucci G, Gregorio GV, et al. The role of HBV DNA quantitative PCR in monitoring the response to interferon treatment in chronic hepatitis B virus infection. J Hepatol 1999;30(6):965-9
    • (1999) J Hepatol , vol.30 , Issue.6 , pp. 965-969
    • Nagata, I.1    Colucci, G.2    Gregorio, G.V.3
  • 10
    • 84880636445 scopus 로고    scopus 로고
    • The natural course of chronic hepatitis B virus infection and its management
    • Hadziyannis SJ, Vassilopoulos D, Hadziyannis E. The natural course of chronic hepatitis B virus infection and its management. Adv Pharmacol 2013;67: 247-91
    • (2013) Adv Pharmacol , vol.67 , pp. 247-291
    • Hadziyannis, S.J.1    Vassilopoulos, D.2    Hadziyannis, E.3
  • 11
    • 0028920984 scopus 로고
    • Treatment of chronic anti-HBe-positive hepatitis B with interferon-Alpha
    • Brunetto MR, Oliveri F, Colombatto P, et al. Treatment of chronic anti-HBe-positive hepatitis B with interferon-Alpha. J Hepatol 1995; 22(1 Suppl):42-4
    • (1995) J Hepatol , vol.22 , Issue.1 SUPPL. , pp. 42-44
    • Brunetto, M.R.1    Oliveri, F.2    Colombatto, P.3
  • 12
    • 0034802538 scopus 로고    scopus 로고
    • Hepatitis B e antigen-negative chronic hepatitis B
    • Hadziyannis SJ, Vassilopoulos D. Hepatitis B e antigen-negative chronic hepatitis B. Hepatology 2001;34(4 Pt 1):617-24
    • (2001) Hepatology , vol.34 , Issue.4 PART 1 , pp. 617-624
    • Hadziyannis, S.J.1    Vassilopoulos, D.2
  • 13
    • 4544239807 scopus 로고    scopus 로고
    • Peginterferon alfa-2a alone, lamivudine alone, and the two in combination in patients with HBeAg-negative chronic hepatitis B
    • Marcellin P, Lau GK, Bonino F, et al. Peginterferon alfa-2a alone, lamivudine alone, and the two in combination in patients with HBeAg-negative chronic hepatitis B. N Engl J Med 2004;351(12): 1206-17
    • (2004) N Engl J Med , vol.351 , Issue.12 , pp. 1206-1217
    • Marcellin, P.1    Lau, G.K.2    Bonino, F.3
  • 14
    • 21244447705 scopus 로고    scopus 로고
    • Peginterferon Alfa-2a, lamivudine, and the combination for HBeAg-positive chronic hepatitis B
    • Lau GK, Piratvisuth T, Luo KX, et al. Peginterferon Alfa-2a, lamivudine, and the combination for HBeAg-positive chronic hepatitis B. N Engl J Med 2005;352(26): 2682-95
    • (2005) N Engl J Med , vol.352 , Issue.26 , pp. 2682-2695
    • Lau, G.K.1    Piratvisuth, T.2    Luo, K.X.3
  • 15
    • 66449121130 scopus 로고    scopus 로고
    • Sustained response of hepatitis B e antigen-negative patients 3 years after treatment with peginterferon alpha-2a
    • Marcellin P, Bonino F, Lau GK, et al. Sustained response of hepatitis B e antigen-negative patients 3 years after treatment with peginterferon alpha-2a. Gastroenterology 2009;136(7):2169-79; e1-4
    • (2009) Gastroenterology , vol.136 , Issue.7
    • Marcellin, P.1    Bonino, F.2    Lau, G.K.3
  • 16
    • 59149093315 scopus 로고    scopus 로고
    • Hbeag-positive chronic hepatitis b: Why do i treat my patients with pegylated interferon
    • Lau GK. HBeAg-positive chronic hepatitis B: why do I treat my patients with pegylated interferon. Liver Int 2009; 29(Suppl 1):125-9
    • (2009) Liver Int , vol.29 , Issue.SUPPL. 1 , pp. 125-129
    • Lau, G.K.1
  • 17
    • 65449117946 scopus 로고    scopus 로고
    • Hepatitis B virus surface antigen levels: A guide to sustained response to peginterferon alfa-2a in HBeAg-negative chronic hepatitis B
    • Brunetto MR, Moriconi F, Bonino F, et al. Hepatitis B virus surface antigen levels: a guide to sustained response to peginterferon alfa-2a in HBeAg-negative chronic hepatitis B. Hepatology 2009;49(4): 1141-50
    • (2009) Hepatology , vol.49 , Issue.4 , pp. 1141-1150
    • Brunetto, M.R.1    Moriconi, F.2    Bonino, F.3
  • 18
    • 84887993086 scopus 로고    scopus 로고
    • Response to peginterferon alfa-2a (40kd) in hbeag-negative CHB: On-treatment kinetics of HBsAg serum levels vary by HBV genotype
    • Brunetto MR, Marcellin P, Cherubini B, et al. Response to peginterferon alfa-2a (40KD) in HBeAg-negative CHB: on-treatment kinetics of HBsAg serum levels vary by HBV genotype. J Hepatol 2013; 59(6):1153-9
    • (2013) J Hepatol , vol.59 , Issue.6 , pp. 1153-1159
    • Brunetto, M.R.1    Marcellin, P.2    Cherubini, B.3
  • 19
    • 0027378724 scopus 로고
    • Effect of alpha-interferon treatment in patients with hepatitis B e antigen-positive chronic hepatitis B
    • Wong DK, Cheung AM, ORourke K, et al. Effect of alpha-interferon treatment in patients with hepatitis B e antigen-positive chronic hepatitis B. A meta-Analysis. Ann Intern Med 1993;119(4):312-23
    • (1993) A Meta-Analysis. Ann Intern Med , vol.119 , Issue.4 , pp. 312-323
    • Wong, D.K.1    Cheung, A.M.2    Orourke, K.3
  • 20
    • 79958796264 scopus 로고    scopus 로고
    • Natural history of chronic hepatitis b in euro-Mediterranean and African countries
    • Hadziyannis SJ. Natural history of chronic hepatitis B in Euro-Mediterranean and African countries. J Hepatol 2011;55(1): 183-91
    • (2011) J Hepatol , vol.55 , Issue.1 , pp. 183-191
    • Hadziyannis, S.J.1
  • 21
    • 0025650982 scopus 로고
    • Interferon alfa-2b treatment of hbeag negative/serum HBV DNA positive chronic active hepatitis type B
    • Hadziyannis S, Bramou T, Makris A, et al. Interferon alfa-2b treatment of HBeAg negative/serum HBV DNA positive chronic active hepatitis type B. J Hepatol 1990; 11(Suppl 1):S133-6
    • (1990) J Hepatol , vol.11 , Issue.SUPPL. 1
    • Hadziyannis, S.1    Bramou, T.2    Makris, A.3
  • 22
    • 0034950006 scopus 로고    scopus 로고
    • Interferon alpha treatment and retreatment of hepatitis B e antigen-negative chronic hepatitis B
    • Manesis EK, Hadziyannis SJ. Interferon alpha treatment and retreatment of hepatitis B e antigen-negative chronic hepatitis B. Gastroenterology 2001;121(1):101-9
    • (2001) Gastroenterology , vol.121 , Issue.1 , pp. 101-109
    • Manesis, E.K.1    Hadziyannis, S.J.2
  • 23
    • 0141707814 scopus 로고    scopus 로고
    • Treatment of HBeAg-negative chronic hepatitis B with interferon or pegylated interferon
    • Brunetto MR, Oliveri F, Colombatto P, et al. Treatment of HBeAg-negative chronic hepatitis B with interferon or pegylated interferon. J Hepatol 2003;39(Suppl 1): S164-7
    • (2003) J Hepatol , vol.39 , Issue.SUPPL. 1
    • Brunetto, M.R.1    Oliveri, F.2    Colombatto, P.3
  • 24
    • 0030724692 scopus 로고    scopus 로고
    • A randomized, controlled trial of a 24-month course of interferon alfa 2b in patients with chronic hepatitis B who had hepatitis B virus DNA without hepatitis B e antigen in serum
    • Lampertico P, Del Ninno E, Manzin A, et al. A randomized, controlled trial of a 24-month course of interferon alfa 2b in patients with chronic hepatitis B who had hepatitis B virus DNA without hepatitis B e antigen in serum. Hepatology 1997;26(6): 1621-5
    • (1997) Hepatology , vol.26 , Issue.6 , pp. 1621-1625
    • Lampertico, P.1    Del Ninno, E.2    Manzin, A.3
  • 25
    • 33847410055 scopus 로고    scopus 로고
    • Prediction of treatment-related hbsag loss in hbeag-negative chronic hepatitis B: A clue from serum HBsAg levels
    • Manesis EK, Hadziyannis ES, Angelopoulou OP, Hadziyannis SJ. Prediction of treatment-related HBsAg loss in HBeAG-negative chronic hepatitis B: a clue from serum HBsAg levels. Antivir Ther 2007;12(1):73-82
    • (2007) Antivir Ther , vol.12 , Issue.1 , pp. 73-82
    • Manesis, E.K.1    Hadziyannis, E.S.2    Angelopoulou, O.P.3    Hadziyannis, S.J.4
  • 26
    • 0033803799 scopus 로고    scopus 로고
    • Efficacy of long-term lamivudine monotherapy in patients with hepatitis B e antigen-negative chronic hepatitis B
    • Hadziyannis SJ, Papatheodoridis GV, Dimou E, et al. Efficacy of long-term lamivudine monotherapy in patients with hepatitis B e antigen-negative chronic hepatitis B. Hepatology 2000;32(4 Pt 1): 847-51
    • (2000) Hepatology , vol.32 , Issue.4 PART 1 , pp. 847-851
    • Hadziyannis, S.J.1    Papatheodoridis, G.V.2    Dimou, E.3
  • 27
    • 77956043221 scopus 로고    scopus 로고
    • Peginterferon for chronic hepatitis B: Predicting success with on-treatment benchmarks
    • Moucari R. Peginterferon for chronic hepatitis B: predicting success with on-treatment benchmarks. J Gastroenterol Hepatol 2010;25(9):1474-5
    • (2010) J Gastroenterol Hepatol , vol.25 , Issue.9 , pp. 1474-1475
    • Moucari, R.1
  • 28
    • 65449123444 scopus 로고    scopus 로고
    • Early serum HBsAg drop: A strong predictor of sustained virological response to pegylated interferon alfa-2a in HBeAg-negative patients
    • Moucari R, Mackiewicz V, Lada O, et al. Early serum HBsAg drop: a strong predictor of sustained virological response to pegylated interferon alfa-2a in HBeAg-negative patients. Hepatology 2009; 49(4):1151-7
    • (2009) Hepatology , vol.49 , Issue.4 , pp. 1151-1157
    • Moucari, R.1    Mackiewicz, V.2    Lada, O.3
  • 29
    • 70649104668 scopus 로고    scopus 로고
    • Factors that predict response of patients with hepatitis B e antigen-positive chronic hepatitis B to peginterferon-Alfa
    • Buster EH, Hansen BE, Lau GK, et al. Factors that predict response of patients with hepatitis B e antigen-positive chronic hepatitis B to peginterferon-Alfa. Gastroenterology 2009;137(6):2002-9
    • (2009) Gastroenterology , vol.137 , Issue.6 , pp. 2002-2009
    • Buster, E.H.1    Hansen, B.E.2    Lau, G.K.3
  • 30
    • 77955703978 scopus 로고    scopus 로고
    • Early on-treatment prediction of response to peginterferon alfa-2a for HBeAg-negative chronic hepatitis B using HBsAg and HBV DNA levels
    • Rijckborst V, Hansen BE, Cakaloglu Y, et al. Early on-treatment prediction of response to peginterferon alfa-2a for HBeAg-negative chronic hepatitis B using HBsAg and HBV DNA levels. Hepatology 2010;52(2):454-61
    • (2010) Hepatology , vol.52 , Issue.2 , pp. 454-461
    • Rijckborst, V.1    Hansen, B.E.2    Cakaloglu, Y.3
  • 31
    • 77957958049 scopus 로고    scopus 로고
    • Prediction of sustained response to peginterferon alfa-2b for hepatitis B e antigen-positive chronic hepatitis B using on-treatment hepatitis B surface antigen decline
    • Sonneveld MJ, Rijckborst V, Boucher CA, et al. Prediction of sustained response to peginterferon alfa-2b for hepatitis B e antigen-positive chronic hepatitis B using on-treatment hepatitis B surface antigen decline. Hepatology 2010;52(4):1251-7
    • (2010) Hepatology , vol.52 , Issue.4 , pp. 1251-1257
    • Sonneveld, M.J.1    Rijckborst, V.2    Boucher, C.A.3
  • 32
    • 79951669706 scopus 로고    scopus 로고
    • Kinetics of hepatitis B surface antigen differ between treatment with peginterferon and entecavir
    • Reijnders JG, Rijckborst V, Sonneveld MJ, et al. Kinetics of hepatitis B surface antigen differ between treatment with peginterferon and entecavir. J Hepatol 2011;54(3):449-54
    • (2011) J Hepatol , vol.54 , Issue.3 , pp. 449-454
    • Reijnders, J.G.1    Rijckborst, V.2    Sonneveld, M.J.3
  • 33
    • 33749819988 scopus 로고    scopus 로고
    • Quantitative analysis of hbsag, igm anti-hbc and anti-HBc avidity in acute and chronic hepatitis B
    • Rodella A, Galli C, Terlenghi L, et al. Quantitative analysis of HBsAg, IgM anti-HBc and anti-HBc avidity in acute and chronic hepatitis B. J Clin Virol 2006; 37(3):206-12
    • (2006) J Clin Virol , vol.37 , Issue.3 , pp. 206-212
    • Rodella, A.1    Galli, C.2    Terlenghi, L.3
  • 34
    • 80455179623 scopus 로고    scopus 로고
    • Multicenter evaluation of the Elecsys hepatitis B surface antigen quantitative assay
    • Zacher BJ, Moriconi F, Bowden S, et al. Multicenter evaluation of the Elecsys hepatitis B surface antigen quantitative assay. Clin Vaccine Immunol 2011;18(11): 1943-50
    • (2011) Clin Vaccine Immunol , vol.18 , Issue.11 , pp. 1943-1950
    • Zacher, B.J.1    Moriconi, F.2    Bowden, S.3
  • 35
    • 67349183743 scopus 로고    scopus 로고
    • Structure of hepatitis B surface antigen from subviral tubes determined by electron cryomicroscopy
    • Short JM, Chen S, Roseman AM, et al. Structure of hepatitis B surface antigen from subviral tubes determined by electron cryomicroscopy. J Mol Biol 2009;390(1): 135-41
    • (2009) J Mol Biol , vol.390 , Issue.1 , pp. 135-141
    • Short, J.M.1    Chen, S.2    Roseman, A.M.3
  • 36
    • 77957346775 scopus 로고    scopus 로고
    • Molecular genetics of HBV infection
    • Locarnini S, Zoulim F. Molecular genetics of HBV infection. Antivir Ther 2010; 15(Suppl 3):3-14
    • (2010) Antivir Ther , vol.15 , Issue.SUPPL. 3 , pp. 3-14
    • Locarnini, S.1    Zoulim, F.2
  • 37
    • 0028346964 scopus 로고
    • Measurement of HBsAg to monitor hepatitis B viral replication in patients on alpha-interferon therapy
    • Janssen HL, Kerhof-Los CJ, Heijtink RA, Schalm SW. Measurement of HBsAg to monitor hepatitis B viral replication in patients on alpha-interferon therapy. Antiviral Res 1994;23(3-4):251-7
    • (1994) Antiviral Res , vol.23 , Issue.3-4 , pp. 251-257
    • Janssen, H.L.1    Kerhof-Los, C.J.2    Heijtink, R.A.3    Schalm, S.W.4
  • 38
    • 0026573670 scopus 로고
    • New assays for quantitative determination of viral markers in management of chronic hepatitis B virus infection
    • Zoulim F, Mimms L, Floreani M, et al. New assays for quantitative determination of viral markers in management of chronic hepatitis B virus infection. J Clin Microbiol 1992;30(5):1111-19
    • (1992) J Clin Microbiol , vol.30 , Issue.5 , pp. 1111-1119
    • Zoulim, F.1    Mimms, L.2    Floreani, M.3
  • 39
    • 19944427203 scopus 로고    scopus 로고
    • Quantitative detection of hepatitis B surface antigen by chemiluminescent microparticle immunoassay during lamivudine treatment of chronic hepatitis B virus carriers
    • Kohmoto M, Enomoto M, Tamori A, et al. Quantitative detection of hepatitis B surface antigen by chemiluminescent microparticle immunoassay during lamivudine treatment of chronic hepatitis B virus carriers. J Med Virol 2005;75(2):235-9
    • (2005) J Med Virol , vol.75 , Issue.2 , pp. 235-239
    • Kohmoto, M.1    Enomoto, M.2    Tamori, A.3
  • 40
    • 54449096510 scopus 로고    scopus 로고
    • Virion half-life in chronic hepatitis B infection is strongly correlated with levels of viremia
    • Dandri M, Murray JM, Lutgehetmann M, et al. Virion half-life in chronic hepatitis B infection is strongly correlated with levels of viremia. Hepatology 2008;48(4):1079-86
    • (2008) Hepatology , vol.48 , Issue.4 , pp. 1079-1086
    • Dandri, M.1    Murray, J.M.2    Lutgehetmann, M.3
  • 41
    • 36549058611 scopus 로고    scopus 로고
    • Serum hepatitis B surface antigen quantitation can reflect hepatitis B virus in the liver and predict treatment response
    • Chan HL, Wong VW, Tse AM, et al. Serum hepatitis B surface antigen quantitation can reflect hepatitis B virus in the liver and predict treatment response. Clin Gastroenterol Hepatol 2007;5(12): 1462-8
    • (2007) Clin Gastroenterol Hepatol , vol.5 , Issue.12 , pp. 1462-1468
    • Chan, H.L.1    Wong, V.W.2    Tse, A.M.3
  • 42
    • 2942532722 scopus 로고    scopus 로고
    • Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy
    • Werle-Lapostolle B, Bowden S, Locarnini S, et al. Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy. Gastroenterology 2004;126(7):1750-8
    • (2004) Gastroenterology , vol.126 , Issue.7 , pp. 1750-1758
    • Werle-Lapostolle, B.1    Bowden, S.2    Locarnini, S.3
  • 43
    • 33748929265 scopus 로고    scopus 로고
    • Peginterferon alpha-2b plus adefovir induce strong cccDNA decline and HBsAg reduction in patients with chronic hepatitis B
    • Wursthorn K, Lutgehetmann M, Dandri M, et al. Peginterferon alpha-2b plus adefovir induce strong cccDNA decline and HBsAg reduction in patients with chronic hepatitis B. Hepatology 2006;44(3):675-84
    • (2006) Hepatology , vol.44 , Issue.3 , pp. 675-684
    • Wursthorn, K.1    Lutgehetmann, M.2    Dandri, M.3
  • 44
    • 84872498407 scopus 로고    scopus 로고
    • Clinical utility of quantitative hbsag in natural history and nucleos(t)ide analogue treatment of chronic hepatitis B: New trick of old dog
    • Tseng TC, Kao JH. Clinical utility of quantitative HBsAg in natural history and nucleos(t)ide analogue treatment of chronic hepatitis B: new trick of old dog. J Gastroenterol 2013;48(1):13-21
    • (2013) J Gastroenterol , vol.48 , Issue.1 , pp. 13-21
    • Tseng, T.C.1    Kao, J.H.2
  • 45
    • 84877928029 scopus 로고    scopus 로고
    • Focus: Quantitative hbsag measurement as a new surrogate marker for assessment of hepatic fibrosis in HBeAg+ chronic hepatitis B
    • Shouval D. Focus: quantitative HBsAg measurement as a new surrogate marker for assessment of hepatic fibrosis in HBeAg+ chronic hepatitis B. J Hepatol 2013;58(6): 1063-4
    • (2013) J Hepatol , vol.58 , Issue.6 , pp. 1063-1064
    • Shouval, D.1
  • 46
    • 79958800541 scopus 로고    scopus 로고
    • Hepatitis B surface antigen: Relation to hepatitis B replication parameters in HBeAg-negative chronic hepatitis B
    • Manesis EK, Papatheodoridis GV, Tiniakos DG, et al. Hepatitis B surface antigen: relation to hepatitis B replication parameters in HBeAg-negative chronic hepatitis B. J Hepatol 2011;55(1):61-8
    • (2011) J Hepatol , vol.55 , Issue.1 , pp. 61-68
    • Manesis, E.K.1    Papatheodoridis, G.V.2    Tiniakos, D.G.3
  • 47
    • 79955086702 scopus 로고    scopus 로고
    • Quantification of HBsAg: Basic virology for clinical practice
    • Lee JM, Ahn SH. Quantification of HBsAg: basic virology for clinical practice. World J Gastroenterol 2011;17(3):283-9
    • (2011) World J Gastroenterol , vol.17 , Issue.3 , pp. 283-289
    • Lee, J.M.1    Ahn, S.H.2
  • 48
    • 84880939335 scopus 로고    scopus 로고
    • Long-term hepatitis b surface antigen (hbsag) kinetics during nucleoside/ nucleotide analogue therapy: Finite treatment duration unlikely
    • Chevaliez S, Hezode C, Bahrami S, et al. Long-term hepatitis B surface antigen (HBsAg) kinetics during nucleoside/ nucleotide analogue therapy: finite treatment duration unlikely. J Hepatol 2013;58(4): 676-83
    • (2013) J Hepatol , vol.58 , Issue.4 , pp. 676-683
    • Chevaliez, S.1    Hezode, C.2    Bahrami, S.3
  • 49
    • 84864360861 scopus 로고    scopus 로고
    • Hepatitis B surface antigen quantification: Not what it seems on the surface
    • Locarnini S, Bowden S. Hepatitis B surface antigen quantification: not what it seems on the surface. Hepatology 2012;56(2):411-14
    • (2012) Hepatology , vol.56 , Issue.2 , pp. 411-414
    • Locarnini, S.1    Bowden, S.2
  • 50
    • 84880962974 scopus 로고    scopus 로고
    • Shouval D. Focus. J Hepatol 2013;58(4): 641-2
    • (2013) J Hepatol , vol.58 , Issue.4 , pp. 641-642
    • Shouval, D.1
  • 51
    • 79958840661 scopus 로고    scopus 로고
    • Engineering virus-specific t cells that target hbv infected hepatocytes and hepatocellular carcinoma cell lines
    • Gehring AJ, Xue SA, Ho ZZ, et al. Engineering virus-specific T cells that target HBV infected hepatocytes and hepatocellular carcinoma cell lines. J Hepatol 2011;55(1):103-10
    • (2011) J Hepatol , vol.55 , Issue.1 , pp. 103-110
    • Gehring, A.J.1    Xue, S.A.2    Ho, Z.Z.3
  • 52
    • 84883110374 scopus 로고    scopus 로고
    • The anti-hbv effect mediated by a novel recombinant eukaryotic expression vector for IFN-Alpha
    • Yu H, Hou Z, Han Q, et al. The anti-HBV effect mediated by a novel recombinant eukaryotic expression vector for IFN-Alpha. Virol J 2013;10(1):270
    • (2013) Virol J , vol.10 , Issue.1 , pp. 270
    • Yu, H.1    Hou, Z.2    Han, Q.3
  • 53
    • 80054724912 scopus 로고    scopus 로고
    • Hepatitis B surface antigen quantification: Why and how to use it in 2011 - A core group report
    • Chan HL, Thompson A, Martinot-Peignoux M, et al. Hepatitis B surface antigen quantification: why and how to use it in 2011 - a core group report. J Hepatol 2011;55(5):112131
    • (2011) J Hepatol , vol.55 , Issue.5 , pp. 112131
    • Chan, H.L.1    Thompson, A.2    Martinot-Peignoux, M.3
  • 54
    • 78649559595 scopus 로고    scopus 로고
    • Serum HBsAg levels during peginterferon alpha-2a treatment with or without thymosin alpha-1 in HBeAg-positive chronic hepatitis B patients
    • Song EY, Shin Y, Roh EY, et al. Serum HBsAg levels during peginterferon alpha-2a treatment with or without thymosin alpha-1 in HBeAg-positive chronic hepatitis B patients. J Med Virol 2011;83(1):88-94
    • (2011) J Med Virol , vol.83 , Issue.1 , pp. 88-94
    • Song, E.Y.1    Shin, Y.2    Roh, E.Y.3
  • 55
    • 84862776715 scopus 로고    scopus 로고
    • Early serum hbsag level as a strong predictor of sustained response to peginterferon alfa-2a in HBeAg-negative chronic hepatitis B
    • Peng CY, Lai HC, Li YF, et al. Early serum HBsAg level as a strong predictor of sustained response to peginterferon alfa-2a in HBeAg-negative chronic hepatitis B. Aliment Pharmacol Ther 2012;35(4):458-68
    • (2012) Aliment Pharmacol Ther , vol.35 , Issue.4 , pp. 458-468
    • Peng, C.Y.1    Lai, H.C.2    Li, Y.F.3
  • 56
    • 79955898168 scopus 로고    scopus 로고
    • Correlation of serum hepatitis B surface antigen level with response to entecavir in naive patients with chronic hepatitis B
    • Lee MH, Lee da M, Kim SS, et al. Correlation of serum hepatitis B surface antigen level with response to entecavir in naive patients with chronic hepatitis B. J Med Virol 2011;83(7):1178-86
    • (2011) J Med Virol , vol.83 , Issue.7 , pp. 1178-1186
    • Lee, M.H.1    Lee Da, M.2    Kim, S.S.3
  • 57
    • 80052837790 scopus 로고    scopus 로고
    • Serum hepatitis B surface antigen monitoring in long-term lamivudine-treated hepatitis B virus patients
    • Gramenzi A, Loggi E, Micco L, et al. Serum hepatitis B surface antigen monitoring in long-term lamivudine-treated hepatitis B virus patients. J Viral Hepat 2011;18(10):e468-74
    • (2011) J Viral Hepat , vol.18 , Issue.10
    • Gramenzi, A.1    Loggi, E.2    Micco, L.3
  • 59
    • 84884416192 scopus 로고    scopus 로고
    • Patterns of hepatitis B surface antigen decline and HBV DNA suppression in Asian treatment-experienced chronic hepatitis B patients after three years of tenofovir treatment
    • Seto WK, Liu K, Wong DK, et al. Patterns of hepatitis B surface antigen decline and HBV DNA suppression in Asian treatment-experienced chronic hepatitis B patients after three years of tenofovir treatment. J Hepatol 2013;59(4):709-16
    • (2013) J Hepatol , vol.59 , Issue.4 , pp. 709-716
    • Seto, W.K.1    Liu, K.2    Wong, D.K.3
  • 60
    • 84883212438 scopus 로고    scopus 로고
    • Reduction of hepatitis B surface antigen levels and hepatitis B surface antigen seroclearance in chronic hepatitis B patients receiving 10 years of nucleoside analogue therapy
    • Seto WK, Wong DK, Fung J, et al. Reduction of hepatitis B surface antigen levels and hepatitis B surface antigen seroclearance in chronic hepatitis B patients receiving 10 years of nucleoside analogue therapy. Hepatology 2013;58(3):923-31
    • (2013) Hepatology , vol.58 , Issue.3 , pp. 923-931
    • Seto, W.K.1    Wong, D.K.2    Fung, J.3
  • 61
    • 84865535075 scopus 로고    scopus 로고
    • A large case-control study on the predictability of hepatitis B surface antigen levels three years before hepatitis B surface antigen seroclearance
    • Seto WK, Wong DK, Fung J, et al. A large case-control study on the predictability of hepatitis B surface antigen levels three years before hepatitis B surface antigen seroclearance. Hepatology 2012;56(3): 812-19
    • (2012) Hepatology , vol.56 , Issue.3 , pp. 812-819
    • Seto, W.K.1    Wong, D.K.2    Fung, J.3
  • 62
    • 0344737590 scopus 로고    scopus 로고
    • Quantitation of hepatitis B surface antigen by an automated chemiluminescent microparticle immunoassay
    • Deguchi M, Yamashita N, Kagita M, et al. Quantitation of hepatitis B surface antigen by an automated chemiluminescent microparticle immunoassay. J Virol Methods 2004;115(2):217-22
    • (2004) J Virol Methods , vol.115 , Issue.2 , pp. 217-222
    • Deguchi, M.1    Yamashita, N.2    Kagita, M.3
  • 64
    • 79959247715 scopus 로고    scopus 로고
    • A comparison of two assays for quantification of Hepatitis B surface Antigen in patients with chronic hepatitis B
    • Sonneveld MJ, Rijckborst V, Boucher CA, et al. A comparison of two assays for quantification of Hepatitis B surface Antigen in patients with chronic hepatitis B. J Clin Virol 2011;51(3):175-8
    • (2011) J Clin Virol , vol.51 , Issue.3 , pp. 175-178
    • Sonneveld, M.J.1    Rijckborst, V.2    Boucher, C.A.3
  • 65
    • 79952623084 scopus 로고    scopus 로고
    • Correlation between the elecsys hbsag ii assay and the Architect assay for the quantification of hepatitis B surface antigen (HBsAg) in the serum
    • Wursthorn K, Jaroszewicz J, Zacher BJ, et al. Correlation between the Elecsys HBsAg II assay and the Architect assay for the quantification of hepatitis B surface antigen (HBsAg) in the serum. J Clin Virol 2011;50(4):292-6
    • (2011) J Clin Virol , vol.50 , Issue.4 , pp. 292-296
    • Wursthorn, K.1    Jaroszewicz, J.2    Zacher, B.J.3
  • 66
    • 84862592289 scopus 로고    scopus 로고
    • Performance evaluation of new automated hepatitis B viral markers in the clinical laboratory: Two quantitative hepatitis B surface antigen assays and an HBV core-related antigen assay
    • Park Y, Hong DJ, Shin S, et al. Performance evaluation of new automated hepatitis B viral markers in the clinical laboratory: two quantitative hepatitis B surface antigen assays and an HBV core-related antigen assay. Am J Clin Pathol 2012;137(5):770-7
    • (2012) Am J Clin Pathol , vol.137 , Issue.5 , pp. 770-777
    • Park, Y.1    Hong, D.J.2    Shin, S.3
  • 67
    • 84861681078 scopus 로고    scopus 로고
    • The detection of hbsag mutants expressed in vitro using two different quantitative HBsAg assays
    • Verheyen J, Neumann-Fraune M, Berg T, et al. The detection of HBsAg mutants expressed in vitro using two different quantitative HBsAg assays. J Clin Virol 2012;54(3):279-81
    • (2012) J Clin Virol , vol.54 , Issue.3 , pp. 279-281
    • Verheyen, J.1    Neumann-Fraune, M.2    Berg, T.3
  • 68
    • 84893138389 scopus 로고    scopus 로고
    • Quantification of hbsag in serum: Characteristics of the assays
    • Hadziyannis E. Quantification of HBsAg in serum: characteristics of the assays. OA Hepatology 2013;1(1):1
    • (2013) OA Hepatology , vol.1 , Issue.1 , pp. 1
    • Hadziyannis, E.1
  • 69
    • 84882856674 scopus 로고    scopus 로고
    • Anti-hbv treatment induces novel reverse transcriptase mutations with reflective effect on HBV S antigen
    • Cento V, Van Hemert F, Neumann-Fraune M, et al. Anti-HBV treatment induces novel reverse transcriptase mutations with reflective effect on HBV S antigen. J Infect 2013;67(4):303-12
    • (2013) J Infect , vol.67 , Issue.4 , pp. 303-312
    • Cento, V.1    Van Hemert, F.2    Neumann-Fraune, M.3
  • 70
    • 77949656255 scopus 로고    scopus 로고
    • Hepatitis b surface antigen (hbsag) levels in the natural history of hepatitis B virus (HBV)-infection: A European perspective
    • Jaroszewicz J, Calle Serrano B, Wursthorn K, et al. Hepatitis B surface antigen (HBsAg) levels in the natural history of hepatitis B virus (HBV)-infection: a European perspective. J Hepatol 2010; 52(4):514-22
    • (2010) J Hepatol , vol.52 , Issue.4 , pp. 514-522
    • Jaroszewicz, J.1    Calle Serrano, B.2    Wursthorn, K.3
  • 71
    • 77949655619 scopus 로고    scopus 로고
    • Hepatitis b surface antigen levels during the natural history of chronic hepatitis B: A perspective on Asia
    • Nguyen T, Thompson AJ, Bowden S, et al. Hepatitis B surface antigen levels during the natural history of chronic hepatitis B: a perspective on Asia. J Hepatol 2010;52(4): 508-13
    • (2010) J Hepatol , vol.52 , Issue.4 , pp. 508-513
    • Nguyen, T.1    Thompson, A.J.2    Bowden, S.3
  • 72
    • 79958062779 scopus 로고    scopus 로고
    • The change of the quantitative HBsAg level during the natural course of chronic hepatitis B
    • Kim YJ, Cho HC, Choi MS, et al. The change of the quantitative HBsAg level during the natural course of chronic hepatitis B. Liver Int 2011;31(6):817-23
    • (2011) Liver Int , vol.31 , Issue.6 , pp. 817-823
    • Kim, Y.J.1    Cho, H.C.2    Choi, M.S.3
  • 73
    • 83355173908 scopus 로고    scopus 로고
    • Hbsag titers in the different phases of hepatitis b infection in Syrian patients
    • Antaki N, Zeidane N, Alhaj N, et al. HBsAg titers in the different phases of hepatitis B infection in Syrian patients. J Clin Virol 2012;53(1):60-4
    • (2012) J Clin Virol , vol.53 , Issue.1 , pp. 60-64
    • Antaki, N.1    Zeidane, N.2    Alhaj, N.3
  • 74
    • 84881030857 scopus 로고    scopus 로고
    • Hbsag quantification to predict natural history and treatment outcome in chronic hepatitis B patients
    • Martinot-Peignoux M, Asselah T, Marcellin P. HBsAg quantification to predict natural history and treatment outcome in chronic hepatitis B patients. Clin Liver Dis 2013;17(3):399-412
    • (2013) Clin Liver Dis , vol.17 , Issue.3 , pp. 399-412
    • Martinot-Peignoux, M.1    Asselah, T.2    Marcellin, P.3
  • 75
    • 84872045830 scopus 로고    scopus 로고
    • The role of hbsag quantification for monitoring natural history and treatment outcome
    • Martinot-Peignoux M, Lapalus M, Asselah T, Marcellin P. The role of HBsAg quantification for monitoring natural history and treatment outcome. Liver Int 2013; 33(Suppl 1):125-32
    • (2013) Liver Int , vol.33 , Issue.SUPPL. 1 , pp. 125-132
    • Martinot-Peignoux, M.1    Lapalus, M.2    Asselah, T.3    Marcellin, P.4
  • 76
    • 84867237643 scopus 로고    scopus 로고
    • Hepatitis b virus basal core promoter mutations A1762T/G1764A are associated with genotype C and a low serum HBsAg level in chronically-infected HBeAg-positive Chinese patients
    • Yan CH, Zhao CY, Ding H, et al. Hepatitis B virus basal core promoter mutations A1762T/G1764A are associated with genotype C and a low serum HBsAg level in chronically-infected HBeAg-positive Chinese patients. Antiviral Res 2012;96(2): 108-14
    • (2012) Antiviral Res , vol.96 , Issue.2 , pp. 108-114
    • Yan, C.H.1    Zhao, C.Y.2    Ding, H.3
  • 77
    • 84884531711 scopus 로고    scopus 로고
    • Prediction of disease reactivation in asymptomatic hepatitis B e antigen-negative chronic hepatitis B patients using baseline serum measurements of HBsAg and HBV-DNA
    • Martinot-Peignoux M, Lapalus M, Laouenan C, et al. Prediction of disease reactivation in asymptomatic hepatitis B e antigen-negative chronic hepatitis B patients using baseline serum measurements of HBsAg and HBV-DNA. J Clin Virol 2013; 58(2):401-7
    • (2013) J Clin Virol , vol.58 , Issue.2 , pp. 401-407
    • Martinot-Peignoux, M.1    Lapalus, M.2    Laouenan, C.3
  • 78
    • 84983723470 scopus 로고    scopus 로고
    • Longitudinal change of hbsag in hbeag-negative patients with genotype B or C infection
    • Su TH, Liu CJ, Tseng TC, et al. Longitudinal change of HBsAg in HBeAg-negative patients with genotype B or C infection. PLoS ONE 2013;8(2):e55916
    • (2013) PLoS ONE , vol.8 , Issue.2
    • Su, T.H.1    Liu, C.J.2    Tseng, T.C.3
  • 79
    • 84983726112 scopus 로고    scopus 로고
    • High levels of hepatitis B surface antigen increase risk of hepatocellular carcinoma in patients with low HBV load
    • quiz e13-4
    • Tseng TC, Liu CJ, Yang HC, et al. High levels of hepatitis B surface antigen increase risk of hepatocellular carcinoma in patients with low HBV load. Gastroenterology 2012; 142(5):1140-9.e3; quiz e13-4
    • (2012) Gastroenterology , vol.142 , Issue.5
    • Tseng, T.C.1    Liu, C.J.2    Yang, H.C.3
  • 80
    • 78449281983 scopus 로고    scopus 로고
    • Serum hbsag quantification to predict response to peginterferon therapy of e antigen positive chronic hepatitis B
    • Chan HL, Wong VW, Chim AM, et al. Serum HBsAg quantification to predict response to peginterferon therapy of e antigen positive chronic hepatitis B. Aliment Pharmacol Ther 2010;32(11-12):1323-31
    • (2010) Aliment Pharmacol Ther , vol.32 , Issue.11-12 , pp. 1323-1331
    • Chan, H.L.1    Wong, V.W.2    Chim, A.M.3
  • 81
    • 84860320431 scopus 로고    scopus 로고
    • Hepatitis b surface antigen: Association with sustained response to peginterferon alfa-2a in hepatitis B e antigen-positive patients
    • Epub ahead of print
    • Piratvisuth T, Marcellin P, Popescu M, et al. Hepatitis B surface antigen: association with sustained response to peginterferon alfa-2a in hepatitis B e antigen-positive patients. Hepatol Int 2011; Epub ahead of print
    • (2011) Hepatol Int
    • Piratvisuth, T.1    Marcellin, P.2    Popescu, M.3
  • 82
    • 77953282645 scopus 로고    scopus 로고
    • Comparison between quantitative hepatitis B surface antigen hepatitis B e-Antigen and hepatitis B virus DNA levels for predicting virological response to pegylated interferon-Alpha-2b therapy in hepatitis B e-Antigen-positive chronic hepatitis B
    • Tangkijvanich P, Komolmit P, Mahachai V, et al. Comparison between quantitative hepatitis B surface antigen, hepatitis B e-Antigen and hepatitis B virus DNA levels for predicting virological response to pegylated interferon-Alpha-2b therapy in hepatitis B e-Antigen-positive chronic hepatitis B. Hepatol Res 2010;40(4):269-77
    • (2010) Hepatol Res , vol.40 , Issue.4 , pp. 269-277
    • Tangkijvanich, P.1    Komolmit, P.2    Mahachai, V.3
  • 83
    • 84894679544 scopus 로고    scopus 로고
    • Clinical significance and evolution of hepatic hbsag expression in HBeAg-positive patients receiving interferon therapy
    • Epub ahead of print
    • Su TH, Liu CJ, Yang HC, et al. Clinical significance and evolution of hepatic HBsAg expression in HBeAg-positive patients receiving interferon therapy. J Gastroenterol 2013; Epub ahead of print
    • (2013) J Gastroenterol
    • Su, T.H.1    Liu, C.J.2    Yang, H.C.3
  • 84
    • 84883532800 scopus 로고    scopus 로고
    • Quantification of serum hepatitis B surface antigen in predicting the response of pegylated interferon alfa-2a in HBeAg-positive chronic hepatitis B with prior lamivudine exposure
    • Weng M, Zeng WZ, Wu XL, et al. Quantification of serum hepatitis B surface antigen in predicting the response of pegylated interferon alfa-2a in HBeAg-positive chronic hepatitis B with prior lamivudine exposure. Virol J 2013; 10(1):277
    • (2013) Virol J , vol.10 , Issue.1 , pp. 277
    • Weng, M.1    Zeng, W.Z.2    Wu, X.L.3
  • 85
    • 84879943305 scopus 로고    scopus 로고
    • Prediction of response to interferon alpha-1b in HBeAg-positive chronic hepatitis B: A clue from HBsAg levels
    • Ma Q, Qin B, Gong X, Lu X. Prediction of response to interferon alpha-1b in HBeAg-positive chronic hepatitis B: a clue from HBsAg levels. Eur J Gastroenterol Hepatol 2013;25(7):820-4
    • (2013) Eur J Gastroenterol Hepatol , vol.25 , Issue.7 , pp. 820-824
    • Ma, Q.1    Qin, B.2    Gong, X.3    Lu, X.4
  • 86
    • 79957494401 scopus 로고    scopus 로고
    • Clinical utility of hepatitis B surface antigen quantitation in patients with chronic hepatitis B: A review
    • Liaw YF. Clinical utility of hepatitis B surface antigen quantitation in patients with chronic hepatitis B: a review. Hepatology 2011;53(6):2121-9
    • (2011) Hepatology , vol.53 , Issue.6 , pp. 2121-2129
    • Liaw, Y.F.1
  • 87
    • 84856203453 scopus 로고    scopus 로고
    • Durable hepatitis B surface antigen decline in hepatitis B e antigen-positive chronic hepatitis B patients treated with pegylated interferon-Alpha2b: Relation to response and HBV genotype
    • Sonneveld MJ, Rijckborst V, Cakaloglu Y, et al. Durable hepatitis B surface antigen decline in hepatitis B e antigen-positive chronic hepatitis B patients treated with pegylated interferon-Alpha2b: relation to response and HBV genotype. Antivir Ther 2012;17(1):9-17
    • (2012) Antivir Ther , vol.17 , Issue.1 , pp. 9-17
    • Sonneveld, M.J.1    Rijckborst, V.2    Cakaloglu, Y.3
  • 88
    • 84883257597 scopus 로고    scopus 로고
    • Response-guided peginterferon therapy in hepatitis B e antigen-positive chronic hepatitis B using serum hepatitis B surface antigen levels
    • Sonneveld MJ, Hansen BE, Piratvisuth T, et al. Response-guided peginterferon therapy in hepatitis B e antigen-positive chronic hepatitis B using serum hepatitis B surface antigen levels. Hepatology 2013;58(3): 872-80
    • (2013) Hepatology , vol.58 , Issue.3 , pp. 872-880
    • Sonneveld, M.J.1    Hansen, B.E.2    Piratvisuth, T.3
  • 89
    • 84871208547 scopus 로고    scopus 로고
    • Close monitoring of hepatitis B surface antigen levels helps classify flares during peginterferon therapy and predicts treatment response
    • Sonneveld MJ, Zoutendijk R, Flink HJ, et al. Close monitoring of hepatitis B surface antigen levels helps classify flares during peginterferon therapy and predicts treatment response. Clin Infect Dis 2013; 56(1):100-5
    • (2013) Clin Infect Dis , vol.56 , Issue.1 , pp. 100-105
    • Sonneveld, M.J.1    Zoutendijk, R.2    Flink, H.J.3
  • 90
    • 84859734382 scopus 로고    scopus 로고
    • Validation of a stopping rule at week 12 using hbsag and hbv dna for hbeag-negative patients treated with peginterferon alfa-2a
    • Rijckborst V, Hansen BE, Ferenci P, et al. Validation of a stopping rule at week 12 using HBsAg and HBV DNA for HBeAg-negative patients treated with peginterferon alfa-2a. J Hepatol 2012;56(5): 1006-11
    • (2012) J Hepatol , vol.56 , Issue.5 , pp. 1006-1011
    • Rijckborst, V.1    Hansen, B.E.2    Ferenci, P.3
  • 91
    • 84875432848 scopus 로고    scopus 로고
    • Use of quantitative serum HBsAg for optimization of therapy in chronic hepatitis B patients treated with pegylated interferon alfa-2a: A Romanian cohort study
    • Gheorghita VI, Caruntu FA, Curescu M, et al. Use of quantitative serum HBsAg for optimization of therapy in chronic hepatitis B patients treated with pegylated interferon alfa-2a: a Romanian cohort study. J Gastrointestin Liver Dis 2013;22(1):27-32
    • (2013) J Gastrointestin Liver Dis , vol.22 , Issue.1 , pp. 27-32
    • Gheorghita, V.I.1    Caruntu, F.A.2    Curescu, M.3
  • 92
    • 79955093993 scopus 로고    scopus 로고
    • Quantitative hepatitis B surface antigen and hepatitis B e antigen titers in prediction of treatment response to entecavir
    • Lee JM, Ahn SH, Kim HS, et al. Quantitative hepatitis B surface antigen and hepatitis B e antigen titers in prediction of treatment response to entecavir. Hepatology 2011;53(5):1486-93
    • (2011) Hepatology , vol.53 , Issue.5 , pp. 1486-1493
    • Lee, J.M.1    Ahn, S.H.2    Kim, H.S.3
  • 93
    • 84880608443 scopus 로고    scopus 로고
    • Reduction of hepatitis b surface antigen and covalently closed circular DNA by nucleos (t)ide analogues of different potency
    • Wong DK, Seto WK, Fung J, et al. Reduction of hepatitis B surface antigen and covalently closed circular DNA by nucleos (t)ide analogues of different potency. Clin Gastroenterol Hepatol 2013;11(8): 1004-10; e1
    • (2013) Clin Gastroenterol Hepatol , vol.11 , Issue.8
    • Wong, D.K.1    Seto, W.K.2    Fung, J.3
  • 94
    • 80053894414 scopus 로고    scopus 로고
    • Quantitative hepatitis B surface antigen levels in patients with chronic hepatitis B after 2 years of entecavir treatment
    • Fung J, Lai CL, Young J, et al. Quantitative hepatitis B surface antigen levels in patients with chronic hepatitis B after 2 years of entecavir treatment. Am J Gastroenterol 2011;106(10):1766-73
    • (2011) Am J Gastroenterol , vol.106 , Issue.10 , pp. 1766-1773
    • Fung, J.1    Lai, C.L.2    Young, J.3
  • 95
    • 77956592924 scopus 로고    scopus 로고
    • Kinetics of hepatitis B surface antigen decline during 3 years of telbivudine treatment in hepatitis B e antigen-positive patients
    • Wursthorn K, Jung M, Riva A, et al. Kinetics of hepatitis B surface antigen decline during 3 years of telbivudine treatment in hepatitis B e antigen-positive patients. Hepatology 2010;52(5):1611-20
    • (2010) Hepatology , vol.52 , Issue.5 , pp. 1611-1620
    • Wursthorn, K.1    Jung, M.2    Riva, A.3
  • 96
    • 77950594817 scopus 로고    scopus 로고
    • On-treatment serum hbsag level is predictive of sustained off-treatment virologic response to telbivudine in HBeAg-positive chronic hepatitis B patients
    • Cai W, Xie Q, An B, et al. On-treatment serum HBsAg level is predictive of sustained off-treatment virologic response to telbivudine in HBeAg-positive chronic hepatitis B patients. J Clin Virol 2010; 48(1):22-6
    • (2010) J Clin Virol , vol.48 , Issue.1 , pp. 22-26
    • Cai, W.1    Xie, Q.2    An, B.3
  • 97
    • 84884417244 scopus 로고    scopus 로고
    • Quantitative hepatitis B surface antigen analysis in hepatitis B e antigen-positive nucleoside-naive patients treated with entecavir
    • Gish RG, Chang TT, Lai CL, et al. Quantitative hepatitis B surface antigen analysis in hepatitis B e antigen-positive nucleoside-naive patients treated with entecavir. Antivir Ther 2013;18(5):691-8
    • (2013) Antivir Ther , vol.18 , Issue.5 , pp. 691-698
    • Gish, R.G.1    Chang, T.T.2    Lai, C.L.3
  • 98
    • 84890566066 scopus 로고    scopus 로고
    • Changes of hbsag and interferon-inducible protein 10 serum levels in naive HBeAg-negative chronic hepatitis B patients under 4-year entecavir therapy
    • Papatheodoridis G, Goulis J, Manolakopoulos S, et al. Changes of HBsAg and interferon-inducible protein 10 serum levels in naive HBeAg-negative chronic hepatitis B patients under 4-year entecavir therapy. J Hepatol 2013;60(1): 62-8
    • (2013) J Hepatol , vol.60 , Issue.1 , pp. 62-68
    • Papatheodoridis, G.1    Goulis, J.2    Manolakopoulos, S.3
  • 99
    • 84873911922 scopus 로고    scopus 로고
    • Quantitation of hbsag predicts response to entecavir therapy in HBV genotype C patients
    • Orito E, Fujiwara K, Kanie H, et al. Quantitation of HBsAg predicts response to entecavir therapy in HBV genotype C patients. World J Gastroenterol 2012; 18(39):5570-5
    • (2012) World J Gastroenterol , vol.18 , Issue.39 , pp. 5570-5575
    • Orito, E.1    Fujiwara, K.2    Kanie, H.3
  • 100
    • 84897601666 scopus 로고    scopus 로고
    • Differential roles of serum hbv dna and hbsag level in predicting virological breakthrough in patients receiving lamivudine therapy
    • Su CW, Wu CY, Hung HH, et al. Differential roles of serum HBV DNA and HBsAg level in predicting virological breakthrough in patients receiving lamivudine therapy. J Gastroenterol Hepatol 2013;28(12):1849-58
    • (2013) J Gastroenterol Hepatol , vol.28 , Issue.12 , pp. 1849-1858
    • Su, C.W.1    Wu, C.Y.2    Hung, H.H.3
  • 101
    • 79960124298 scopus 로고    scopus 로고
    • Serum hbsag decline during long-term potent nucleos(t)ide analogue therapy for chronic hepatitis B and prediction of HBsAg loss
    • Zoutendijk R, Hansen BE, van Vuuren AJ, et al. Serum HBsAg decline during long-term potent nucleos(t)ide analogue therapy for chronic hepatitis B and prediction of HBsAg loss. J Infect Dis 2011;204(3):415-18
    • (2011) J Infect Dis , vol.204 , Issue.3 , pp. 415-418
    • Zoutendijk, R.1    Hansen, B.E.2    Van Vuuren, A.J.3
  • 102
    • 84875055002 scopus 로고    scopus 로고
    • Kinetics and prediction of hbsag loss during therapy with analogues in patients affected by chronic hepatitis B HBeAg negative and genotype D
    • Boglione L, DAvolio A, Cariti G, et al. Kinetics and prediction of HBsAg loss during therapy with analogues in patients affected by chronic hepatitis B HBeAg negative and genotype D. Liver Int 2013; 33(4):580-5
    • (2013) Liver Int , vol.33 , Issue.4 , pp. 580-585
    • Boglione, L.1    Davolio, A.2    Cariti, G.3
  • 103
    • 84893036210 scopus 로고    scopus 로고
    • Serum hepatitis B surface antigen kinetics in severe reactivation of hepatitis e antigen negative chronic hepatitis B patients receiving nucleos(t)ide analogues
    • Epub ahead of print
    • Wong GL, Chan HL, Lo AO, et al. Serum hepatitis B surface antigen kinetics in severe reactivation of hepatitis e antigen negative chronic hepatitis B patients receiving nucleos(t)ide analogues. Antivir Ther 2013; Epub ahead of print
    • (2013) Antivir Ther
    • Wong, G.L.1    Chan, H.L.2    Lo, A.O.3
  • 104
    • 84865487986 scopus 로고    scopus 로고
    • Sustained responses and loss of hbsag in hbeag-negative patients with chronic hepatitis B who stop long-term treatment with adefovir
    • Hadziyannis SJ, Sevastianos V, Rapti I, et al. Sustained responses and loss of HBsAg in HBeAg-negative patients with chronic hepatitis B who stop long-term treatment with adefovir. Gastroenterology 2012; 143(3):629-36; e1
    • (2012) Gastroenterology , vol.143 , Issue.3
    • Hadziyannis, S.J.1    Sevastianos, V.2    Rapti, I.3
  • 105
    • 83455163799 scopus 로고    scopus 로고
    • Prediction of off-treatment response to lamivudine by serum hepatitis B surface antigen quantification in hepatitis B e antigen-negative patients
    • Chan HL, Wong GL, Chim AM, et al. Prediction of off-treatment response to lamivudine by serum hepatitis B surface antigen quantification in hepatitis B e antigen-negative patients. Antivir Ther 2011;16(8):1249-57
    • (2011) Antivir Ther , vol.16 , Issue.8 , pp. 1249-1257
    • Chan, H.L.1    Wong, G.L.2    Chim, A.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.