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Volumn 40, Issue 3, 2010, Pages 269-277

Comparison between quantitative hepatitis B surface antigen, hepatitis B e-antigen and hepatitis B virus DNA levels for predicting virological response to pegylated interferon-α-2b therapy in hepatitis B e-antigen-positive chronic hepatitis B

Author keywords

Covalently closed circular DNA; Hepatitis B e antigen; Hepatitis B surface antigen; Hepatitis B virus DNA; Pegylated interferon; Quantification; Virological response

Indexed keywords

HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIGEN; PEGINTERFERON ALPHA2B; VIRUS DNA;

EID: 77953282645     PISSN: 13866346     EISSN: 1872034X     Source Type: Journal    
DOI: 10.1111/j.1872-034X.2009.00592.x     Document Type: Article
Times cited : (35)

References (34)
  • 1
    • 1542316127 scopus 로고    scopus 로고
    • Hepatitis b virus infection - natural history and clinical consequences
    • Ganem D, Prince AM. Hepatitis b virus infection - natural history and clinical consequences. N Engl J Med 2004, 350:1118-29.
    • (2004) N Engl J Med , vol.350 , pp. 1118-1129
    • Ganem, D.1    Prince, A.M.2
  • 2
    • 34247194561 scopus 로고    scopus 로고
    • Management of hepatitis B: summary of a clinical research workshop
    • Hoofnagle JH, Doo E, Liang TJ, Fleischer R, Lok AS. Management of hepatitis B: summary of a clinical research workshop. Hepatology 2007, 45:1056-75.
    • (2007) Hepatology , vol.45 , pp. 1056-1075
    • Hoofnagle, J.H.1    Doo, E.2    Liang, T.J.3    Fleischer, R.4    Lok, A.S.5
  • 4
    • 33646366401 scopus 로고    scopus 로고
    • Serological and molecular diagnosis
    • Bowden S. Serological and molecular diagnosis. Semin Liver Dis 2006, 26:97-103.
    • (2006) Semin Liver Dis , vol.26 , pp. 97-103
    • Bowden, S.1
  • 5
    • 65449117946 scopus 로고    scopus 로고
    • Hepatitis B virus surface antigen levels: a guide to sustained response to peginterferon alfa-2a in HBeAg-negative chronic hepatitis B
    • Brunetto MR, Moriconi F, Bonino F. Hepatitis B virus surface antigen levels: a guide to sustained response to peginterferon alfa-2a in HBeAg-negative chronic hepatitis B. Hepatology 2008, 49:1141-50.
    • (2008) Hepatology , vol.49 , pp. 1141-1150
    • Brunetto, M.R.1    Moriconi, F.2    Bonino, F.3
  • 6
    • 36549058611 scopus 로고    scopus 로고
    • Serum hepatitis B surface antigen quantitation can reflect hepatitis B virus in the liver and predict treatment response
    • Chan HL, Wong VW, Tse AM. Serum hepatitis B surface antigen quantitation can reflect hepatitis B virus in the liver and predict treatment response. Clin Gastroenterol Hepatol 2007, 5:1462-8.
    • (2007) Clin Gastroenterol Hepatol , vol.5 , pp. 1462-1468
    • Chan, H.L.1    Wong, V.W.2    Tse, A.M.3
  • 7
    • 39549114267 scopus 로고    scopus 로고
    • HBeAg and hepatitis B virus DNA as outcome predictors during therapy with peginterferon alfa-2a for HBeAg-positive chronic hepatitis B
    • Fried MW, Piratvisuth T, Lau GK. HBeAg and hepatitis B virus DNA as outcome predictors during therapy with peginterferon alfa-2a for HBeAg-positive chronic hepatitis B. Hepatology 2008, 47:428-34.
    • (2008) Hepatology , vol.47 , pp. 428-434
    • Fried, M.W.1    Piratvisuth, T.2    Lau, G.K.3
  • 8
    • 65449123444 scopus 로고    scopus 로고
    • Early serum HBsAg drop: a strong predictor of sustained virological response to pegylated interferon alfa-2a in HBeAg-negative patients
    • Moucari R, Mackiewicz V, Lada O. Early serum HBsAg drop: a strong predictor of sustained virological response to pegylated interferon alfa-2a in HBeAg-negative patients. Hepatology 2008, 49:1151-7.
    • (2008) Hepatology , vol.49 , pp. 1151-1157
    • Moucari, R.1    Mackiewicz, V.2    Lada, O.3
  • 9
    • 53849141188 scopus 로고    scopus 로고
    • Correlation of quantitative assay of HBsAg and HBV DNA levels during chronic HBV treatment
    • Ozaras R, Tabak F, Tahan V. Correlation of quantitative assay of HBsAg and HBV DNA levels during chronic HBV treatment. Dig Dis Sci 2008, 53:2995-8.
    • (2008) Dig Dis Sci , vol.53 , pp. 2995-2998
    • Ozaras, R.1    Tabak, F.2    Tahan, V.3
  • 10
    • 0019813866 scopus 로고
    • Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis
    • Knodell RG, Ishak KG, Black WC. Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology 1981, 1:431-5.
    • (1981) Hepatology , vol.1 , pp. 431-435
    • Knodell, R.G.1    Ishak, K.G.2    Black, W.C.3
  • 11
    • 38749126832 scopus 로고    scopus 로고
    • Virologic monitoring of hepatitis B virus therapy in clinical trials and practice: recommendations for a standardized approach
    • Pawlotsky JM, Dusheiko G, Hatzakis A. Virologic monitoring of hepatitis B virus therapy in clinical trials and practice: recommendations for a standardized approach. Gastroenterology 2008, 134:405-15.
    • (2008) Gastroenterology , vol.134 , pp. 405-415
    • Pawlotsky, J.M.1    Dusheiko, G.2    Hatzakis, A.3
  • 12
    • 0344737590 scopus 로고    scopus 로고
    • Quantitation of hepatitis B surface antigen by an automated chemiluminescent microparticle immunoassay
    • Deguchi M, Yamashita N, Kagita M. Quantitation of hepatitis B surface antigen by an automated chemiluminescent microparticle immunoassay. J Virol Methods 2004, 115:217-22.
    • (2004) J Virol Methods , vol.115 , pp. 217-222
    • Deguchi, M.1    Yamashita, N.2    Kagita, M.3
  • 13
    • 47649103303 scopus 로고    scopus 로고
    • A decline in hepatitis B virus surface antigen (hbsag) predicts clearance, but does not correlate with quantitative hbeag or HBV DNA levels
    • Wiegand J, Wedemeyer H, Finger A. A decline in hepatitis B virus surface antigen (hbsag) predicts clearance, but does not correlate with quantitative hbeag or HBV DNA levels. Antivir Ther 2008, 13:547-54.
    • (2008) Antivir Ther , vol.13 , pp. 547-554
    • Wiegand, J.1    Wedemeyer, H.2    Finger, A.3
  • 15
  • 16
    • 33847757812 scopus 로고    scopus 로고
    • Effective quantitative real-time polymerase chain reaction analysis of the parkin gene (PARK2) exon 1-12 dosage
    • Shadrina MI, Semenova EV, Slominsky PA. Effective quantitative real-time polymerase chain reaction analysis of the parkin gene (PARK2) exon 1-12 dosage. BMC Med Genet 2007, 8:6.
    • (2007) BMC Med Genet , vol.8 , pp. 6
    • Shadrina, M.I.1    Semenova, E.V.2    Slominsky, P.A.3
  • 17
    • 54849146600 scopus 로고    scopus 로고
    • Hepatitis B virus infection
    • Dienstag JL. Hepatitis B virus infection. N Engl J Med 2008, 359:1486-500.
    • (2008) N Engl J Med , vol.359 , pp. 1486-1500
    • Dienstag, J.L.1
  • 18
    • 53549107488 scopus 로고    scopus 로고
    • Meta-analysis: treatment of hepatitis B infection reduces risk of hepatocellular carcinoma
    • Sung JJ, Tsoi KK, Wong VW, Li KC, Chan HL. Meta-analysis: treatment of hepatitis B infection reduces risk of hepatocellular carcinoma. Aliment Pharmacol Ther 2008, 28:1067-77.
    • (2008) Aliment Pharmacol Ther , vol.28 , pp. 1067-1077
    • Sung, J.J.1    Tsoi, K.K.2    Wong, V.W.3    Li, K.C.4    Chan, H.L.5
  • 19
    • 61449187479 scopus 로고    scopus 로고
    • Interferon therapy in chronic hepatitis B reduces progression to cirrhosis and hepatocellular carcinoma: a meta-analysis
    • Yang YF, Zhao W, Zhong YD, Xia HM, Shen L, Zhang N. Interferon therapy in chronic hepatitis B reduces progression to cirrhosis and hepatocellular carcinoma: a meta-analysis. J Viral Hepat 2009, 16:265-71.
    • (2009) J Viral Hepat , vol.16 , pp. 265-271
    • Yang, Y.F.1    Zhao, W.2    Zhong, Y.D.3    Xia, H.M.4    Shen, L.5    Zhang, N.6
  • 20
    • 19944428132 scopus 로고    scopus 로고
    • Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: a randomised trial
    • Janssen HL, van Zonneveld M, Senturk H. Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: a randomised trial. Lancet 2005, 365:123-9.
    • (2005) Lancet , vol.365 , pp. 123-129
    • Janssen, H.L.1    van Zonneveld, M.2    Senturk, H.3
  • 21
    • 21244447705 scopus 로고    scopus 로고
    • Peginterferon Alfa-2a, lamivudine, and the combination for HBeAg-positive chronic hepatitis B
    • Lau GK, Piratvisuth T, Luo KX. Peginterferon Alfa-2a, lamivudine, and the combination for HBeAg-positive chronic hepatitis B. N Engl J Med 2005, 352:2682-95.
    • (2005) N Engl J Med , vol.352 , pp. 2682-2695
    • Lau, G.K.1    Piratvisuth, T.2    Luo, K.X.3
  • 22
    • 33748939050 scopus 로고    scopus 로고
    • Intrahepatic levels and replicative activity of covalently closed circular hepatitis B virus DNA in chronically infected patients
    • Laras A, Koskinas J, Dimou E, Kostamena A, Hadziyannis SJ. Intrahepatic levels and replicative activity of covalently closed circular hepatitis B virus DNA in chronically infected patients. Hepatology 2006, 44:694-702.
    • (2006) Hepatology , vol.44 , pp. 694-702
    • Laras, A.1    Koskinas, J.2    Dimou, E.3    Kostamena, A.4    Hadziyannis, S.J.5
  • 23
    • 2942532722 scopus 로고    scopus 로고
    • Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy
    • Werle-Lapostolle B, Bowden S, Locarnini S. Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy. Gastroenterology 2004, 126:1750-8.
    • (2004) Gastroenterology , vol.126 , pp. 1750-1758
    • Werle-Lapostolle, B.1    Bowden, S.2    Locarnini, S.3
  • 24
    • 4644296081 scopus 로고    scopus 로고
    • Quantitation of covalently closed circular hepatitis B virus DNA in chronic hepatitis B patients
    • Wong DK, Yuen MF, Yuan H. Quantitation of covalently closed circular hepatitis B virus DNA in chronic hepatitis B patients. Hepatology 2004, 40:727-37.
    • (2004) Hepatology , vol.40 , pp. 727-737
    • Wong, D.K.1    Yuen, M.F.2    Yuan, H.3
  • 25
    • 20444505037 scopus 로고    scopus 로고
    • Intrahepatic hepatitis B virus covalently closed circular DNA can be a predictor of sustained response to therapy
    • Sung JJ, Wong ML, Bowden S. Intrahepatic hepatitis B virus covalently closed circular DNA can be a predictor of sustained response to therapy. Gastroenterology 2005, 128:1890-7.
    • (2005) Gastroenterology , vol.128 , pp. 1890-1897
    • Sung, J.J.1    Wong, M.L.2    Bowden, S.3
  • 26
    • 13844250599 scopus 로고    scopus 로고
    • New insight on hepatitis B virus persistence from the study of intrahepatic viral cccDNA
    • Zoulim F. New insight on hepatitis B virus persistence from the study of intrahepatic viral cccDNA. J Hepatol 2005, 42:302-8.
    • (2005) J Hepatol , vol.42 , pp. 302-308
    • Zoulim, F.1
  • 27
    • 33748929265 scopus 로고    scopus 로고
    • Peginterferon alpha-2b plus adefovir induce strong cccDNA decline and HBsAg reduction in patients with chronic hepatitis B
    • Wursthorn K, Lutgehetmann M, Dandri M. Peginterferon alpha-2b plus adefovir induce strong cccDNA decline and HBsAg reduction in patients with chronic hepatitis B. Hepatology 2006, 44:675-84.
    • (2006) Hepatology , vol.44 , pp. 675-684
    • Wursthorn, K.1    Lutgehetmann, M.2    Dandri, M.3
  • 28
    • 33847410055 scopus 로고    scopus 로고
    • Prediction of treatment-related HBsAg loss in HBeAG-negative chronic hepatitis B: a clue from serum HBsAg levels
    • Manesis EK, Hadziyannis ES, Angelopoulou OP, Hadziyannis SJ. Prediction of treatment-related HBsAg loss in HBeAG-negative chronic hepatitis B: a clue from serum HBsAg levels. Antiviral therapy 2007, 12:73-82.
    • (2007) Antiviral therapy , vol.12 , pp. 73-82
    • Manesis, E.K.1    Hadziyannis, E.S.2    Angelopoulou, O.P.3    Hadziyannis, S.J.4
  • 29
    • 0029806124 scopus 로고    scopus 로고
    • Use of quantitative assays for hepatitis B e antigen and IgM antibody to hepatitis B core antigen to monitor therapy in chronic hepatitis B
    • Hayashi PH, Beames MP, Kuhns MC, Hoofnagle JH, Di Bisceglie AM. Use of quantitative assays for hepatitis B e antigen and IgM antibody to hepatitis B core antigen to monitor therapy in chronic hepatitis B. Am J Gastroenterol 1996, 91:2323-8.
    • (1996) Am J Gastroenterol , vol.91 , pp. 2323-2328
    • Hayashi, P.H.1    Beames, M.P.2    Kuhns, M.C.3    Hoofnagle, J.H.4    Di Bisceglie, A.M.5
  • 30
    • 0033816667 scopus 로고    scopus 로고
    • Interferon-alpha therapy in chronic hepatitis B: early monitoring of hepatitis B e antigen may help to decide whether to stop or to prolong therapy
    • Heijtink RA, Janssen HL, Hop WC, Osterhaus AD, Schalm SW. Interferon-alpha therapy in chronic hepatitis B: early monitoring of hepatitis B e antigen may help to decide whether to stop or to prolong therapy. J Viral Hepat 2000, 7:382-6.
    • (2000) J Viral Hepat , vol.7 , pp. 382-386
    • Heijtink, R.A.1    Janssen, H.L.2    Hop, W.C.3    Osterhaus, A.D.4    Schalm, S.W.5
  • 31
    • 0027486290 scopus 로고
    • Monitoring of antiviral therapy with quantitative evaluation of HBeAg: a comparison with HBV DNA testing
    • Perrillo R, Mimms L, Schechtman K, Robbins D, Campbell C. Monitoring of antiviral therapy with quantitative evaluation of HBeAg: a comparison with HBV DNA testing. Hepatology 1993, 18:1306-12.
    • (1993) Hepatology , vol.18 , pp. 1306-1312
    • Perrillo, R.1    Mimms, L.2    Schechtman, K.3    Robbins, D.4    Campbell, C.5
  • 32
    • 33748951529 scopus 로고    scopus 로고
    • Patterns of viral decline during PEG-interferon alpha-2b therapy in HBeAg-positive chronic hepatitis B: relation to treatment response
    • ter Borg MJ, van Zonneveld M, Zeuzem S. Patterns of viral decline during PEG-interferon alpha-2b therapy in HBeAg-positive chronic hepatitis B: relation to treatment response. Hepatology 2006, 44:721-7.
    • (2006) Hepatology , vol.44 , pp. 721-727
    • ter Borg, M.J.1    van Zonneveld, M.2    Zeuzem, S.3
  • 33
    • 50649117758 scopus 로고    scopus 로고
    • DNA suppression can predict virologic response to peginterferon and lamivudine treatment
    • Chan HL, Wong VW, Wong GL. DNA suppression can predict virologic response to peginterferon and lamivudine treatment. Clin Gastroenterol Hepatol 2008, 6:1022-6.
    • (2008) Clin Gastroenterol Hepatol , vol.6 , pp. 1022-1026
    • Chan, H.L.1    Wong, V.W.2    Wong, G.L.3
  • 34
    • 30144440293 scopus 로고    scopus 로고
    • Virology of hepatitis B and C viruses and antiviral targets
    • Pawlotsky JM. Virology of hepatitis B and C viruses and antiviral targets. J Hepatol 2006, 44:S10-13.
    • (2006) J Hepatol , vol.44
    • Pawlotsky, J.M.1


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