Hepatitis B surface antigen quantification: Not what it seems on the surface

Hepatology

Volumn 56, Issue 2, 2012, Pages 411-414

  Locarnini, Stephen ^a   Bowden, Scott ^a  

^a VICTORIAN INFECTIOUS DISEASES REFERENCE LABORATORY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; DIHYDROLIPOAMIDE DEHYDROGENASE; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIGEN; MESSENGER RNA; NUCLEOSIDE ANALOG; PEGINTERFERON; RECOMBINANT ALPHA INTERFERON; RNA DIRECTED DNA POLYMERASE; VIRUS DNA; VIRUS ENVELOPE PROTEIN; VITRONECTIN;

ANTIVIRAL ACTIVITY; ANTIVIRAL THERAPY; DRUG EFFECT; EDITORIAL; GENOTYPE; HEPATITIS B; HISTOLOGY; HUMAN; OPEN READING FRAME; PATIENT ASSESSMENT; PHASE 4 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN SECRETION; QUANTITATIVE ANALYSIS; RNA TRANSCRIPTION; START CODON; TREATMENT DURATION; VIRAL CLEARANCE; VIRUS PARTICLE; VIRUS REPLICATION;

FEMALE; GENOME, VIRAL; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HUMANS; MALE;

EID: 84864360861     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.25732     Document Type: Editorial

References (27)

1. Hollinger FB, Sood G. Occult hepatitis B virus infection: a covert operation. J Viral Hepat 2010; 17: 1-15.
2. Seeger C, Mason WS. Hepatitis B virus biology. Microbiol Mol Biol Rev 2000; 64: 51-68.
3. Ganem D. Assembly of hepadnaviral virions and subviral particles. Curr Top Microbiol Immunol 1991; 168: 61-83.
4. De-Medina T, Faktor O, Shaul Y. The S promoter of hepatitis B virus is regulated by positive and negative elements. Mol Cell Biol 1988; 8: 2449-2455.
5. Heermann KH, Goldmann U, Schwartz W, Seyffarth T, Baumgarten H, Gerlich WH. Large surface proteins of hepatitis B virus containing the pre-s sequence. J Virol 1984; 52: 396-402.
6. Bill CA, Summers J. Genomic DNA double-strand breaks are targets for hepadnaviral DNA integration. Proc Natl Acad Sci U S A 2004; 101: 11135-11140.
7. Frosner GG, Schomerus H, Wiedmann KH, Zachoval R, Bayerl B, Backer U, et al. Diagnostic significance of quantitative determination of hepatitis B surface antigen in acute and chronic hepatitis B infection. Eur J Clin Microbiol 1982; 1: 52-58.
8. Hollinger FB. Hepatitis B virus infection and transfusion medicine: science and the occult. Transfusion 2008; 48: 1001-1026.
9. Wursthorn K, Jaroszewicz J, Zacher BJ, Darnedde M, Raupach R, Mederacke I, et al. Correlation between the Elecsys HBsAg II assay and the Architect assay for the quantification of hepatitis B surface antigen (HBsAg) in the serum. J Clin Virol 2011; 50: 292-296.
10. Chan HL, Wong VW, Tse AM, Tse CH, Chim AM, Chan HY, et al. Serum hepatitis B surface antigen quantitation can reflect hepatitis B virus in the liver and predict treatment response. Clin Gastroenterol Hepatol 2007; 5: 1462-1468.
11. Chan HL, Wong VW, Wong GL, Tse CH, Chan HY, Sung JJ. A longitudinal study on the natural history of serum hepatitis B surface antigen changes in chronic hepatitis B. HEPATOLOGY 2010; 52: 1232-1241.
12. Jaroszewicz J, Calle Serrano B, Wursthorn K, Deterding K, Schlue J, Raupach R, et al. Hepatitis B surface antigen (HBsAg) levels in the natural history of hepatitis B virus (HBV)-infection: a European perspective. J Hepatol 2010; 52: 514-522.
13. Nguyen T, Thompson AJ, Bowden S, Croagh C, Bell S, Desmond PV, et al. Hepatitis B surface antigen levels during the natural history of chronic hepatitis B: a perspective on Asia. J Hepatol 2010; 52: 508-513.
14. Brunetto MR, Oliveri F, Colombatto P, Moriconi F, Ciccorossi P, Coco B, et al. Hepatitis B surface antigen serum levels help to distinguish active from inactive hepatitis B virus genotype D carriers. Gastroenterology 2010; 139: 483-490.
15. Tseng TC, Liu CJ, Chen CL, Wang CC, Su TH, Kuo SF, et al. Serum hepatitis B virus-DNA levels correlate with long-term adverse outcomes in spontaneous hepatitis B e antigen seroconverters. J Infect Dis 2011; 205: 54-63.
16. EASL Clinical Practice Guidelines: management of chronic hepatitis B. HEPATOLOGY 2009; 50: 227-242.
17. Nguyen T, Locarnini S. Hepatitis: monitoring drug therapy for hepatitis B-a global challenge? Nat Rev Gastroenterol Hepatol 2009; 6: 565-567.
18. Brunetto MR, Moriconi F, Bonino F, Lau GK, Farci P, Yurdaydin C, et al. Hepatitis B virus surface antigen levels: a guide to sustained response to peginterferon alfa-2a in HBeAg-negative chronic hepatitis B. HEPATOLOGY 2009; 49: 1141-1150.
19. Moucari R, Mackiewicz V, Lada O, Ripault MP, Castelnau C, Martinot-Peignoux M, et al. Early serum HBsAg drop: a strong predictor of sustained virological response to pegylated interferon alfa-2a in HBeAg-negative patients. HEPATOLOGY 2009; 49: 1151-1157.
20. Sonneveld MJ, Rijckborst V, Boucher CA, Hansen BE, Janssen HL. Prediction of sustained response to peginterferon alfa-2b for hepatitis B e antigen-positive chronic hepatitis B using on-treatment hepatitis B surface antigen decline. HEPATOLOGY 2010; 52: 1251-1257.
21. Chan HL, Thompson A, Martinot-Peignoux M, Piratvisuth T, Cornberg M, Brunetto MR, et al. Hepatitis B surface antigen quantification: why and how to use it in 2011 - a core group report. J Hepatol 2011; 55: 1121-1131.
22. Rijckborst V, Hansen BE, Cakaloglu Y, Ferenci P, Tabak F, Akdogan M, et al. Early on-treatment prediction of response to peginterferon alfa-2a for HBeAg-negative chronic hepatitis B using HBsAg and HBV DNA levels. HEPATOLOGY 2010; 52: 454-461.
23. Pollicino T, Amaddeo G, Restuccia A, Raffa G, Alibrandi A, Cutroneo G, et al. Impact of hepatitis B virus (HBV) preS/S genomic variability on HBV surface antigen and HBV DNA serum levels. HEPATOLOGY 2012; 56: 434-443.
24. Chen BF, Liu CJ, Jow GM, Chen PJ, Kao JH, Chen DS. High prevalence and mapping of pre-S deletion in hepatitis B virus carriers with progressive liver diseases. Gastroenterology 2006; 130: 1153-1168.
25. Pollicino T, Campo S, Raimondo G. PreS and core gene heterogeneity in hepatitis B virus (HBV) genomes isolated from patients with long-lasting HBV chronic infection. Virology 1995; 208: 672-677.
26. Bock CT, Tillmann HL, Manns MP, Trautwein C. The pre-S region determines the intracellular localization and appearance of hepatitis B virus. HEPATOLOGY 1999; 30: 517-525.
27. Xu Z, Yen TS. Intracellular retention of surface protein by a hepatitis B virus mutant that releases virion particles. J Virol 1996; 70: 133-140.