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Volumn 137, Issue 6, 2009, Pages 2002-2009

Factors That Predict Response of Patients With Hepatitis B e Antigen-Positive Chronic Hepatitis B to Peginterferon-Alfa

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; HEPATITIS B(E) ANTIGEN; LAMIVUDINE; PEGINTERFERON ALPHA2A; PEGINTERFERON ALPHA2B; VIRUS DNA;

EID: 70649104668     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2009.08.061     Document Type: Article
Times cited : (345)

References (47)
  • 1
    • 1642410856 scopus 로고    scopus 로고
    • Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures
    • Lavanchy D. Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures. J Viral Hepat 11 (2004) 97-107
    • (2004) J Viral Hepat , vol.11 , pp. 97-107
    • Lavanchy, D.1
  • 2
    • 0023243960 scopus 로고
    • Spontaneous hepatitis B e antigen to antibody seroconversion and reversion in Chinese patients with chronic hepatitis B virus infection
    • Lok A.S., Lai C.L., Wu P.C., et al. Spontaneous hepatitis B e antigen to antibody seroconversion and reversion in Chinese patients with chronic hepatitis B virus infection. Gastroenterology 92 (1987) 1839-1843
    • (1987) Gastroenterology , vol.92 , pp. 1839-1843
    • Lok, A.S.1    Lai, C.L.2    Wu, P.C.3
  • 3
    • 33847701354 scopus 로고    scopus 로고
    • Chronic hepatitis B
    • Lok A.S., and McMahon B.J. Chronic hepatitis B. Hepatology 45 (2007) 507-539
    • (2007) Hepatology , vol.45 , pp. 507-539
    • Lok, A.S.1    McMahon, B.J.2
  • 4
    • 19544391413 scopus 로고    scopus 로고
    • Lamivudine for patients with chronic hepatitis B and advanced liver disease
    • Liaw Y.F., Sung J.J., Chow W.C., et al. Lamivudine for patients with chronic hepatitis B and advanced liver disease. N Engl J Med 351 (2004) 1521-1531
    • (2004) N Engl J Med , vol.351 , pp. 1521-1531
    • Liaw, Y.F.1    Sung, J.J.2    Chow, W.C.3
  • 5
    • 1542724805 scopus 로고    scopus 로고
    • Long-term follow-up of alpha-interferon treatment of patients with chronic hepatitis B
    • van Zonneveld M., Honkoop P., Hansen B.E., et al. Long-term follow-up of alpha-interferon treatment of patients with chronic hepatitis B. Hepatology 39 (2004) 804-810
    • (2004) Hepatology , vol.39 , pp. 804-810
    • van Zonneveld, M.1    Honkoop, P.2    Hansen, B.E.3
  • 6
    • 48549107919 scopus 로고    scopus 로고
    • Sustained HBeAg and HBsAg loss after long-term follow-up of HBeAg positive patients treated with peginterferon alpha-2b
    • Buster E.H., Flink H.J., Cakaloglu Y., et al. Sustained HBeAg and HBsAg loss after long-term follow-up of HBeAg positive patients treated with peginterferon alpha-2b. Gastroenterology 135 (2008) 459-467
    • (2008) Gastroenterology , vol.135 , pp. 459-467
    • Buster, E.H.1    Flink, H.J.2    Cakaloglu, Y.3
  • 7
    • 0030730879 scopus 로고    scopus 로고
    • Long-term follow-up of patients with chronic hepatitis B treated with interferon alfa
    • Lau D.T., Everhart J., Kleiner D.E., et al. Long-term follow-up of patients with chronic hepatitis B treated with interferon alfa. Gastroenterology 113 (1997) 1660-1667
    • (1997) Gastroenterology , vol.113 , pp. 1660-1667
    • Lau, D.T.1    Everhart, J.2    Kleiner, D.E.3
  • 8
    • 0033027690 scopus 로고    scopus 로고
    • Long-term beneficial effect of interferon therapy in patients with chronic hepatitis B virus infection
    • Lin S.M., Sheen I.S., Chien R.N., et al. Long-term beneficial effect of interferon therapy in patients with chronic hepatitis B virus infection. Hepatology 29 (1999) 971-975
    • (1999) Hepatology , vol.29 , pp. 971-975
    • Lin, S.M.1    Sheen, I.S.2    Chien, R.N.3
  • 9
    • 33644818518 scopus 로고    scopus 로고
    • A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B
    • Chang T.T., Gish R.G., de Man R., et al. A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B. N Engl J Med 354 (2006) 1001-1010
    • (2006) N Engl J Med , vol.354 , pp. 1001-1010
    • Chang, T.T.1    Gish, R.G.2    de Man, R.3
  • 10
    • 19944428132 scopus 로고    scopus 로고
    • Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: a randomised trial
    • Janssen H.L., van Zonneveld M., Senturk H., et al. Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: a randomised trial. Lancet 365 (2005) 123-129
    • (2005) Lancet , vol.365 , pp. 123-129
    • Janssen, H.L.1    van Zonneveld, M.2    Senturk, H.3
  • 11
    • 21244447705 scopus 로고    scopus 로고
    • Peginterferon alfa-2a, lamivudine, and the combination for HBeAg-positive chronic hepatitis B
    • Lau G.K., Piratvisuth T., Luo K.X., et al. Peginterferon alfa-2a, lamivudine, and the combination for HBeAg-positive chronic hepatitis B. N Engl J Med 352 (2005) 2682-2695
    • (2005) N Engl J Med , vol.352 , pp. 2682-2695
    • Lau, G.K.1    Piratvisuth, T.2    Luo, K.X.3
  • 12
    • 0037468421 scopus 로고    scopus 로고
    • Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B
    • Marcellin P., Chang T.T., Lim S.G., et al. Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B. N Engl J Med 348 (2003) 808-816
    • (2003) N Engl J Med , vol.348 , pp. 808-816
    • Marcellin, P.1    Chang, T.T.2    Lim, S.G.3
  • 13
    • 0026695602 scopus 로고
    • Long-term follow-up of hepatitis B chronic carriers who responded to interferon therapy
    • Carreno V., Castillo I., Molina J., et al. Long-term follow-up of hepatitis B chronic carriers who responded to interferon therapy. J Hepatol 15 (1992) 102-106
    • (1992) J Hepatol , vol.15 , pp. 102-106
    • Carreno, V.1    Castillo, I.2    Molina, J.3
  • 14
    • 0030696048 scopus 로고    scopus 로고
    • Long-term outcome of hepatitis B e antigen-positive patients with compensated cirrhosis treated with interferon alfa. European Concerted Action on Viral Hepatitis (EUROHEP)
    • Fattovich G., Giustina G., Realdi G., et al. Long-term outcome of hepatitis B e antigen-positive patients with compensated cirrhosis treated with interferon alfa. European Concerted Action on Viral Hepatitis (EUROHEP). Hepatology 26 (1997) 1338-1342
    • (1997) Hepatology , vol.26 , pp. 1338-1342
    • Fattovich, G.1    Giustina, G.2    Realdi, G.3
  • 15
    • 0025734569 scopus 로고
    • Long-term remission of chronic hepatitis B after alpha-interferon therapy
    • Korenman J., Baker B., Waggoner J., et al. Long-term remission of chronic hepatitis B after alpha-interferon therapy. Ann Intern Med 114 (1991) 629-634
    • (1991) Ann Intern Med , vol.114 , pp. 629-634
    • Korenman, J.1    Baker, B.2    Waggoner, J.3
  • 16
    • 0031769390 scopus 로고    scopus 로고
    • The long-term effect of treatment with interferon-alpha 2a in chronic hepatitis B. The Long-Term Follow-up Investigator Group. The European Study Group on Viral Hepatitis (EUROHEP). Executive Team on Anti-Viral Treatment
    • Krogsgaard K. The long-term effect of treatment with interferon-alpha 2a in chronic hepatitis B. The Long-Term Follow-up Investigator Group. The European Study Group on Viral Hepatitis (EUROHEP). Executive Team on Anti-Viral Treatment. J Viral Hepat 5 (1998) 389-397
    • (1998) J Viral Hepat , vol.5 , pp. 389-397
    • Krogsgaard, K.1
  • 17
    • 0027142488 scopus 로고
    • Long-term follow-up of chronic hepatitis B patients treated with interferon alfa
    • Lok A.S., Chung H.T., Liu V.W., et al. Long-term follow-up of chronic hepatitis B patients treated with interferon alfa. Gastroenterology 105 (1993) 1833-1838
    • (1993) Gastroenterology , vol.105 , pp. 1833-1838
    • Lok, A.S.1    Chung, H.T.2    Liu, V.W.3
  • 18
    • 0029893146 scopus 로고    scopus 로고
    • Long-term follow-up of HBeAg-positive patients treated with interferon alfa for chronic hepatitis B
    • Niederau C., Heintges T., Lange S., et al. Long-term follow-up of HBeAg-positive patients treated with interferon alfa for chronic hepatitis B. N Engl J Med 334 (1996) 1422-1427
    • (1996) N Engl J Med , vol.334 , pp. 1422-1427
    • Niederau, C.1    Heintges, T.2    Lange, S.3
  • 19
    • 20844448900 scopus 로고    scopus 로고
    • The safety of pegylated interferon alpha-2b in the treatment of chronic hepatitis B: predictive factors for dose reduction and treatment discontinuation
    • van Zonneveld M., Flink H.J., Verhey E., et al. The safety of pegylated interferon alpha-2b in the treatment of chronic hepatitis B: predictive factors for dose reduction and treatment discontinuation. Aliment Pharmacol Ther 21 (2005) 1163-1171
    • (2005) Aliment Pharmacol Ther , vol.21 , pp. 1163-1171
    • van Zonneveld, M.1    Flink, H.J.2    Verhey, E.3
  • 20
    • 0037371186 scopus 로고    scopus 로고
    • Durability of HBeAg seroconversion following antiviral therapy for chronic hepatitis B: relation to type of therapy and pretreatment serum hepatitis B virus DNA and alanine aminotransferase
    • van Nunen A.B., Hansen B.E., Suh D.J., et al. Durability of HBeAg seroconversion following antiviral therapy for chronic hepatitis B: relation to type of therapy and pretreatment serum hepatitis B virus DNA and alanine aminotransferase. Gut 52 (2003) 420-424
    • (2003) Gut , vol.52 , pp. 420-424
    • van Nunen, A.B.1    Hansen, B.E.2    Suh, D.J.3
  • 21
    • 0034993211 scopus 로고    scopus 로고
    • Extended lamivudine treatment in patients with chronic hepatitis B enhances hepatitis B e antigen seroconversion rates: results after 3 years of therapy
    • Leung N.W., Lai C.L., Chang T.T., et al. Extended lamivudine treatment in patients with chronic hepatitis B enhances hepatitis B e antigen seroconversion rates: results after 3 years of therapy. Hepatology 33 (2001) 1527-1532
    • (2001) Hepatology , vol.33 , pp. 1527-1532
    • Leung, N.W.1    Lai, C.L.2    Chang, T.T.3
  • 22
    • 8344277996 scopus 로고    scopus 로고
    • Four years of lamivudine treatment in Chinese patients with chronic hepatitis B
    • Chang T.T., Lai C.L., Chien R.N., et al. Four years of lamivudine treatment in Chinese patients with chronic hepatitis B. J Gastroenterol Hepatol 19 (2004) 1276-1282
    • (2004) J Gastroenterol Hepatol , vol.19 , pp. 1276-1282
    • Chang, T.T.1    Lai, C.L.2    Chien, R.N.3
  • 23
    • 33845675367 scopus 로고    scopus 로고
    • Entecavir resistance is rare in nucleoside naive patients with hepatitis B
    • Colonno R.J., Rose R., Baldick C.J., et al. Entecavir resistance is rare in nucleoside naive patients with hepatitis B. Hepatology 44 (2006) 1656-1665
    • (2006) Hepatology , vol.44 , pp. 1656-1665
    • Colonno, R.J.1    Rose, R.2    Baldick, C.J.3
  • 24
    • 33845671388 scopus 로고    scopus 로고
    • Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B for up to 5 years
    • Hadziyannis S.J., Tassopoulos N.C., Heathcote E.J., et al. Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B for up to 5 years. Gastroenterology 131 (2006) 1743-1751
    • (2006) Gastroenterology , vol.131 , pp. 1743-1751
    • Hadziyannis, S.J.1    Tassopoulos, N.C.2    Heathcote, E.J.3
  • 25
    • 24344497489 scopus 로고    scopus 로고
    • Effects of genotype and other baseline factors on response to peginterferon alfa-2a (40 kDa) (Pegasys®) in HBeAg-positive chronic hepatitis B: results from a large, randomised study
    • Cooksley G., Lau G.K.K., Liaw Y.F., et al. Effects of genotype and other baseline factors on response to peginterferon alfa-2a (40 kDa) (Pegasys®) in HBeAg-positive chronic hepatitis B: results from a large, randomised study. J Hepatol 42 (2005) S30
    • (2005) J Hepatol , vol.42
    • Cooksley, G.1    Lau, G.K.K.2    Liaw, Y.F.3
  • 26
    • 24044459887 scopus 로고    scopus 로고
    • The first detailed analysis of predictors of response in HBeAg-negative chronic hepatitis B: data from a multicenter, randomized, partially double-blind study of peginterferon-alfa-2a (4-KD) (Pegasys®) alone or in combination with lamivudine vs lamivudine alone
    • Bonino F., Lau G.K.K., Marcellin P., et al. The first detailed analysis of predictors of response in HBeAg-negative chronic hepatitis B: data from a multicenter, randomized, partially double-blind study of peginterferon-alfa-2a (4-KD) (Pegasys®) alone or in combination with lamivudine vs lamivudine alone. Hepatology 40 (2004) A1142
    • (2004) Hepatology , vol.40
    • Bonino, F.1    Lau, G.K.K.2    Marcellin, P.3
  • 27
    • 58149296156 scopus 로고    scopus 로고
    • EASL Clinical Practice Guidelines: management of chronic hepatitis B
    • European Association for the study of the liver
    • European Association for the study of the liver. EASL Clinical Practice Guidelines: management of chronic hepatitis B. J Hepatol 50 (2009) 227-242
    • (2009) J Hepatol , vol.50 , pp. 227-242
  • 28
    • 0033890782 scopus 로고    scopus 로고
    • Development of a quantitative real-time detection assay for hepatitis B virus DNA and comparison with two commercial assays
    • Pas S.D., Fries E., De Man R.A., et al. Development of a quantitative real-time detection assay for hepatitis B virus DNA and comparison with two commercial assays. J Clin Microbiol 38 (2000) 2897-2901
    • (2000) J Clin Microbiol , vol.38 , pp. 2897-2901
    • Pas, S.D.1    Fries, E.2    De Man, R.A.3
  • 30
    • 0034732710 scopus 로고    scopus 로고
    • Prognostic modelling with logistic regression analysis: a comparison of selection and estimation methods in small data sets
    • Steyerberg E.W., Eijkemans M.J., Harrell Jr. F.E., et al. Prognostic modelling with logistic regression analysis: a comparison of selection and estimation methods in small data sets. Stat Med 19 (2000) 1059-1079
    • (2000) Stat Med , vol.19 , pp. 1059-1079
    • Steyerberg, E.W.1    Eijkemans, M.J.2    Harrell Jr., F.E.3
  • 31
    • 0034906866 scopus 로고    scopus 로고
    • Internal validation of predictive models: efficiency of some procedures for logistic regression analysis
    • Steyerberg E.W., Harrell Jr. F.E., Borsboom G.J., et al. Internal validation of predictive models: efficiency of some procedures for logistic regression analysis. J Clin Epidemiol 54 (2001) 774-781
    • (2001) J Clin Epidemiol , vol.54 , pp. 774-781
    • Steyerberg, E.W.1    Harrell Jr., F.E.2    Borsboom, G.J.3
  • 33
    • 1242302409 scopus 로고    scopus 로고
    • EASL International Consensus Conference on Hepatitis B
    • 13-14 September, 2002, Geneva, Switzerland. Consensus statement (long version)
    • de Franchis R., Hadengue A., Lau G., et al. EASL International Consensus Conference on Hepatitis B. 13-14 September, 2002, Geneva, Switzerland. Consensus statement (long version). J Hepatol 39 (2003) S3-S25
    • (2003) J Hepatol , vol.39
    • de Franchis, R.1    Hadengue, A.2    Lau, G.3
  • 34
    • 51049107683 scopus 로고    scopus 로고
    • Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2008 update
    • Liaw Y.F., Leung N., Kao J.H., et al. Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2008 update. Hepatol Int 2 (2008) 263-283
    • (2008) Hepatol Int , vol.2 , pp. 263-283
    • Liaw, Y.F.1    Leung, N.2    Kao, J.H.3
  • 35
    • 0142244873 scopus 로고    scopus 로고
    • Determinants for sustained HBeAg response to lamivudine therapy
    • Chien R.N., Yeh C.T., Tsai S.L., et al. Determinants for sustained HBeAg response to lamivudine therapy. Hepatology 38 (2003) 1267-1273
    • (2003) Hepatology , vol.38 , pp. 1267-1273
    • Chien, R.N.1    Yeh, C.T.2    Tsai, S.L.3
  • 36
    • 12444287949 scopus 로고    scopus 로고
    • Long-term additional lamivudine therapy enhances durability of lamivudine-induced HBeAg loss: a prospective study
    • Ryu S.H., Chung Y.H., Choi M.H., et al. Long-term additional lamivudine therapy enhances durability of lamivudine-induced HBeAg loss: a prospective study. J Hepatol 39 (2003) 614-619
    • (2003) J Hepatol , vol.39 , pp. 614-619
    • Ryu, S.H.1    Chung, Y.H.2    Choi, M.H.3
  • 37
    • 37349120537 scopus 로고    scopus 로고
    • Telbivudine versus lamivudine in patients with chronic hepatitis B
    • Lai C.L., Gane E., Liaw Y.F., et al. Telbivudine versus lamivudine in patients with chronic hepatitis B. N Engl J Med 357 (2007) 2576-2588
    • (2007) N Engl J Med , vol.357 , pp. 2576-2588
    • Lai, C.L.1    Gane, E.2    Liaw, Y.F.3
  • 38
    • 59149101767 scopus 로고    scopus 로고
    • Sustained durability of HBeAg seroconversion in chronic hepatitis B patients after treatment with telbivudine
    • Poynard T., Hou J.L., Chutaputti A., et al. Sustained durability of HBeAg seroconversion in chronic hepatitis B patients after treatment with telbivudine. J Hepatol 48 (2008) S263-S264
    • (2008) J Hepatol , vol.48
    • Poynard, T.1    Hou, J.L.2    Chutaputti, A.3
  • 39
    • 40849105240 scopus 로고    scopus 로고
    • Hepatitis B: reflections on the current approach to antiviral therapy
    • Zoulim F., and Perrillo R. Hepatitis B: reflections on the current approach to antiviral therapy. J Hepatol 48 Suppl 1 (2008) S2-S19
    • (2008) J Hepatol , vol.48 , Issue.SUPPL. 1
    • Zoulim, F.1    Perrillo, R.2
  • 40
    • 0141637207 scopus 로고    scopus 로고
    • Interferon-alpha for HBeAg-positive chronic hepatitis B
    • Craxi A., Di Bona D., and Camma C. Interferon-alpha for HBeAg-positive chronic hepatitis B. J Hepatol 39 Suppl 1 (2003) S99-S105
    • (2003) J Hepatol , vol.39 , Issue.SUPPL. 1
    • Craxi, A.1    Di Bona, D.2    Camma, C.3
  • 41
    • 39549114267 scopus 로고    scopus 로고
    • HBeAg and hepatitis B virus DNA as outcome predictors during therapy with peginterferon alfa-2a for HBeAg-positive chronic hepatitis B
    • Fried M.W., Piratvisuth T., Lau G.K., et al. HBeAg and hepatitis B virus DNA as outcome predictors during therapy with peginterferon alfa-2a for HBeAg-positive chronic hepatitis B. Hepatology 47 (2008) 428-434
    • (2008) Hepatology , vol.47 , pp. 428-434
    • Fried, M.W.1    Piratvisuth, T.2    Lau, G.K.3
  • 42
    • 70649105911 scopus 로고    scopus 로고
    • Predicting sustained HBeAg loss after treatment with peginterferon alpha-2b: development and validation of a practical model
    • Buster E.H., Hansen B.E., Zeuzem S., et al. Predicting sustained HBeAg loss after treatment with peginterferon alpha-2b: development and validation of a practical model. Hepatology 46 (2007) 684A-685A
    • (2007) Hepatology , vol.46
    • Buster, E.H.1    Hansen, B.E.2    Zeuzem, S.3
  • 43
    • 0033844989 scopus 로고    scopus 로고
    • Rapid detection of genotypes and mutations in the pre-core promoter and the pre-core region of hepatitis B virus genome: correlation with viral persistence and disease severity
    • Grandjacques C., Pradat P., Stuyver L., et al. Rapid detection of genotypes and mutations in the pre-core promoter and the pre-core region of hepatitis B virus genome: correlation with viral persistence and disease severity. J Hepatol 33 (2000) 430-439
    • (2000) J Hepatol , vol.33 , pp. 430-439
    • Grandjacques, C.1    Pradat, P.2    Stuyver, L.3
  • 44
    • 33751514752 scopus 로고    scopus 로고
    • Interferon therapy in HBeAg positive chronic hepatitis reduces progression to cirrhosis and hepatocellular carcinoma
    • Lin S.M., Yu M.L., Lee C.M., et al. Interferon therapy in HBeAg positive chronic hepatitis reduces progression to cirrhosis and hepatocellular carcinoma. J Hepatol 46 (2007) 45-52
    • (2007) J Hepatol , vol.46 , pp. 45-52
    • Lin, S.M.1    Yu, M.L.2    Lee, C.M.3
  • 45
    • 29944436855 scopus 로고    scopus 로고
    • Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level
    • Chen C.J., Yang H.I., Su J., et al. Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level. JAMA 295 (2006) 65-73
    • (2006) JAMA , vol.295 , pp. 65-73
    • Chen, C.J.1    Yang, H.I.2    Su, J.3
  • 46
    • 33644858331 scopus 로고    scopus 로고
    • Predicting cirrhosis risk based on the level of circulating hepatitis B viral load
    • Iloeje U.H., Yang H.I., Su J., et al. Predicting cirrhosis risk based on the level of circulating hepatitis B viral load. Gastroenterology 130 (2006) 678-686
    • (2006) Gastroenterology , vol.130 , pp. 678-686
    • Iloeje, U.H.1    Yang, H.I.2    Su, J.3
  • 47
    • 45549088044 scopus 로고    scopus 로고
    • Virological and biochemical response in patients with HBeAg-negative chronic hepatitis B treated with peginterferon alfa-2a (40kD) with or without lamivudine: results of 4-year follow-up
    • Marcellin P., Piratvisuth T., Brunetto M.R., et al. Virological and biochemical response in patients with HBeAg-negative chronic hepatitis B treated with peginterferon alfa-2a (40kD) with or without lamivudine: results of 4-year follow-up. J Hepatol 48 (2008) S46
    • (2008) J Hepatol , vol.48
    • Marcellin, P.1    Piratvisuth, T.2    Brunetto, M.R.3


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