-
1
-
-
33646337650
-
Hepatocellular carcinoma and hepatitis B virus
-
DOI 10.1055/s-2006-939753
-
Chan HL, Sung JJ. Hepatocellular carcinoma and hepatitis B virus. Semin Liver Dis 2006; 26:153-161. (Pubitemid 43668257)
-
(2006)
Seminars in Liver Disease
, vol.26
, Issue.2
, pp. 153-161
-
-
Chan, H.L.-Y.1
Sung, J.J.-Y.2
-
2
-
-
68549130600
-
A review of the natural history of chronic hepatitis B in the era of transient elastography
-
Chan HL, Wong GL, Wong VW. A review of the natural history of chronic hepatitis B in the era of transient elastography. Antivir Ther 2009; 14:489-499.
-
(2009)
Antivir Ther
, vol.14
, pp. 489-499
-
-
Chan, H.L.1
Wong, G.L.2
Wong, V.W.3
-
3
-
-
0036178339
-
Viral genotype and hepatitis B virus DNA levels are correlated with histological liver damage in HBeAg-negative chronic hepatitis B virus infection
-
DOI 10.1016/S0002-9270(01)04040-0, PII S0002927001040400
-
Chan HL, Tsang SW, Liew CT, et al. Viral genotype and hepatitis B virus DNA levels are correlated with histological liver damage in HBeAg-negative chronic hepatitis B virus infection. Am J Gastroenterol 2002; 97:406-412. (Pubitemid 34160768)
-
(2002)
American Journal of Gastroenterology
, vol.97
, Issue.2
, pp. 406-412
-
-
Chan, H.L.-Y.1
Tsang, S.W.-C.2
Liew, C.-T.3
Tse, C.-H.4
Wong, M.-L.5
Ching, J.Y.-L.6
Leung, N.W.-Y.7
Tam, J.S.-L.8
Sung, J.J.-Y.9
-
4
-
-
0036916045
-
Relationship of clinical and virological factors with hepatitis activity in hepatitis B e antigen-negative chronic hepatitis B virus-infected patients
-
DOI 10.1046/j.1365-2893.2002.00352.x
-
Sung JJ, Chan HL, Wong ML, et al. Relationship of clinical and virological factors with hepatitis activity in hepatitis B e antigen-negative chronic hepatitis B virus-infected patients. J Viral Hepat 2002; 9:229-234. (Pubitemid 36005522)
-
(2002)
Journal of Viral Hepatitis
, vol.9
, Issue.3
, pp. 229-234
-
-
Sung, J.J.-Y.1
Chan, H.L.-Y.2
Wong, M.L.3
Tse, C.-H.4
Yuen, S.C.-H.5
Tam, J.S.-L.6
Leung, N.W.-Y.7
-
5
-
-
29944436855
-
Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA Level
-
DOI 10.1001/jama.295.1.65
-
Chen CJ, Yang HI, Su J, et al. Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level. JAMA 2006; 295:65-73. (Pubitemid 43042691)
-
(2006)
Journal of the American Medical Association
, vol.295
, Issue.1
, pp. 65-73
-
-
Chen, C.-J.1
Yang, H.-I.2
Su, J.3
Jen, C.-L.4
You, S.-L.5
Lu, S.-N.6
Huang, G.-T.7
Iloeje, U.H.8
-
6
-
-
38349094747
-
High viral load and hepatitis B virus subgenotype Ce are associated with increased risk of hepatocellular carcinoma
-
Chan HL, Tse CH, Mo F, et al. High viral load and hepatitis B virus subgenotype Ce are associated with increased risk of hepatocellular carcinoma. J Clin Oncol 2008; 26:177-182.
-
(2008)
J Clin Oncol
, vol.26
, pp. 177-182
-
-
Chan, H.L.1
Tse, C.H.2
Mo, F.3
-
7
-
-
33847701354
-
Chronic hepatitis B
-
DOI 10.1002/hep.21513
-
Lok AS, McMahon BJ. Chronic hepatitis B. Hepatology 2007; 45:507-539. (Pubitemid 46374607)
-
(2007)
Hepatology
, vol.45
, Issue.2
, pp. 507-539
-
-
Lok, A.S.F.1
McMahon, B.J.2
-
8
-
-
58149296156
-
EASL Clinical practice guidelines: Management of chronic hepatitis B
-
European Association for the Study of the Liver
-
European Association for the Study of the Liver. EASL Clinical practice guidelines: management of chronic hepatitis B. J Hepatol 2009; 50:227-242.
-
(2009)
J Hepatol
, vol.50
, pp. 227-242
-
-
-
9
-
-
51049107683
-
Asian-Pacific consensus statement on the management of chronic hepatitis B: A 2008 update
-
Liaw YF, Leung NW, Kao JH, et al. Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2008 update. Hepatol Int. 2008; 2:263-283.
-
(2008)
Hepatol Int.
, vol.2
, pp. 263-283
-
-
Liaw, Y.F.1
Leung, N.W.2
Kao, J.H.3
-
10
-
-
66449121130
-
Sustained response of hepatitis B e antigen-negative patients 3 years after treatment with peginterferon alfa-2a
-
Marcellin P, Bonino F, Lau GK, et al. Sustained response of hepatitis B e antigen-negative patients 3 years after treatment with peginterferon alfa-2a. Gastroenterology 2009; 136:2169-2179.
-
(2009)
Gastroenterology
, vol.136
, pp. 2169-2179
-
-
Marcellin, P.1
Bonino, F.2
Lau, G.K.3
-
11
-
-
57349095400
-
Tenofovir disoproxil fumarate versus adefovir dipivoxil for chronic hepatitis B
-
Marcellin P, Heathcote EJ, Buti M, et al. Tenofovir disoproxil fumarate versus adefovir dipivoxil for chronic hepatitis B. N Engl J Med 2008; 359:2442-2455.
-
(2008)
N Engl J Med
, vol.359
, pp. 2442-2455
-
-
Marcellin, P.1
Heathcote, E.J.2
Buti, M.3
-
12
-
-
37349120537
-
Telbivudine versus lamivudine in patients with chronic hepatitis B
-
DOI 10.1056/NEJMoa066422
-
Lai CL, Gane E, Liaw YF, et al. Telbivudine versus lamivudine in patients with chronic hepatitis B. N Engl J Med 2007; 357:2576-2588. (Pubitemid 350294224)
-
(2007)
New England Journal of Medicine
, vol.357
, Issue.25
, pp. 2576-2588
-
-
Lai, C.-L.1
Gane, E.2
Liaw, Y.-F.3
Hsu, C.-W.4
Thongsawat, S.5
Wang, Y.6
Chen, Y.7
Heathcote, E.J.8
Rasenack, J.9
Bzowej, N.10
Naoumov, N.V.11
Di, B.A.M.12
Zeuzem, S.13
Moon, Y.M.14
Goodman, Z.15
Chao, G.16
Constance, B.F.17
Brown, N.A.18
-
13
-
-
33644822860
-
Entecavir versus lamivudine for patients with HBeAg-negative chronic hepatitis B
-
DOI 10.1056/NEJMoa051287
-
Lai CL, Shouval D, Lok AS, et al. Entecavir versus lamivudine for patients with HBeAg-negative chronic hepatitis B. N Engl J Med 2006; 354:1011-1020. (Pubitemid 43357805)
-
(2006)
New England Journal of Medicine
, vol.354
, Issue.10
, pp. 1011-1020
-
-
Lai, C.-L.1
Shouval, D.2
Lok, A.S.3
Chang, T.-T.4
Cheinquer, H.5
Goodman, Z.6
DeHertogh, D.7
Wilber, R.8
Zink, R.C.9
Cross, A.10
Colonno, R.11
Fernandes, L.12
-
14
-
-
33845671388
-
Long-term Therapy With Adefovir Dipivoxil for HBeAg-Negative Chronic Hepatitis B for up to 5 Years
-
DOI 10.1053/j.gastro.2006.09.020, PII S0016508506020804
-
Hadziyannis SJ, Tassopoulos NC, Heathcote J, et al. Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B for up to 5 years. Gastroenterology 2006; 131:1743-1751. (Pubitemid 44958517)
-
(2006)
Gastroenterology
, vol.131
, Issue.6
, pp. 1743-1751
-
-
Hadziyannis, S.J.1
Tassopoulos, N.C.2
Heathcote, E.J.3
Chang, T.4
Kitis, G.5
Rizzetto, M.6
Marcellin, P.7
Lim, S.G.8
Goodman, Z.9
Ma, J.10
Brosgart, C.L.11
Borroto-Esoda, K.12
Arterburn, S.13
Chuck, S.L.14
-
15
-
-
83455232850
-
Three years efficacy and safety of tenofovir disoproxil fumarate (TDF) in Asians with HBeAg-positive and HBeAg-negative chronic hepatitis B, preliminary analysis
-
Abstract FP-019
-
Gane E, Weilet F, Sievert W, et al. Three years efficacy and safety of tenofovir disoproxil fumarate (TDF) in Asians with HBeAg-positive and HBeAg-negative chronic hepatitis B, preliminary analysis. 20th Conference of the Asian Pacific Association for the Study of the Liver. 25-28 March, 2010, Beijing, China. Abstract FP-019.
-
20th Conference of the Asian Pacific Association for the Study of the Liver. 25-28 March, 2010, Beijing, China
-
-
Gane, E.1
Weilet, F.2
Sievert, W.3
-
16
-
-
83455161473
-
Sustained biochemical and virological remission after discontinuation of 4 to 5 years of adefovir dipivoxil (ADV) treatment in HBeAg-negative chronic hepatitis B
-
Abstract 114
-
Hadziyannis SJ, Sevastianos V, Rapti IN, Tassopoulos N. Sustained biochemical and virological remission after discontinuation of 4 to 5 years of adefovir dipivoxil (ADV) treatment in HBeAg-negative chronic hepatitis B. 57th Annual meeting of The American Association for the Study of Liver Diseases. 27-31 October 2006, Boston, MA, USA. Abstract 114.
-
57th Annual Meeting of the American Association for the Study of Liver Diseases. 27-31 October 2006, Boston, MA, USA
-
-
Hadziyannis, S.J.1
Sevastianos, V.2
Rapti, I.N.3
Tassopoulos, N.4
-
17
-
-
34249090519
-
Two-year lamivudine treatment for hepatitis B e antigen-negative chronic hepatitis B: A double-blind, placebo-controlled trial
-
Chan HL, Wang H, Niu J, Chim AM, Sung JJ. Two-year lamivudine treatment for hepatitis B e antigen-negative chronic hepatitis B: a double-blind, placebo-controlled trial. Antivir Ther 2007; 12:345-353. (Pubitemid 46787979)
-
(2007)
Antiviral Therapy
, vol.12
, Issue.3
, pp. 345-353
-
-
Chan, H.L.-Y.1
Wang, H.2
Niu, J.3
Chim, A.M.-L.4
Sung, J.J.-Y.5
-
18
-
-
33745766453
-
Long-term lamivudine treatment is associated with a good maintained response in severe acute exacerbation of chronic HBeAg-negative hepatitis B
-
Chan HL, Wong VW, Hui AY, et al. Long term lamivudine treatment is associated with good maintained response in severe acute exacerbation of hepatitis B e antigen-negative chronic hepatitis B. Antivir Ther 2006; 11:465-471. (Pubitemid 44024854)
-
(2006)
Antiviral Therapy
, vol.11
, Issue.4
, pp. 465-471
-
-
Chan, H.L.-Y.1
Wong, V.W.-S.2
Hui, A.Y.3
Tsang, S.W.-C.4
Chan, J.L.-Y.5
Chan, H.-Y.6
Wong, G.L.-H.7
Sung, J.J.-Y.8
-
19
-
-
2942532722
-
Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy
-
DOI 10.1053/j.gastro.2004.03.018
-
Werle-Lapostolle B, Bowden S, Locarnini S, et al. Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy. Gastroenterology 2004; 126:1750-1758. (Pubitemid 38736340)
-
(2004)
Gastroenterology
, vol.126
, Issue.7
, pp. 1750-1758
-
-
Werle-Lapostolle, B.1
Bowden, S.2
Locarnini, S.3
Wursthorn, K.4
Petersen, J.5
Lau, G.6
Trepo, C.7
Marcellin, P.8
Goodman, Z.9
Delaney IV, W.E.10
Xiong, S.11
Brosgart, C.L.12
Chen, S.-S.13
Gibbs, C.S.14
Zoulim, F.15
-
20
-
-
36549058611
-
Serum Hepatitis B Surface Antigen Quantitation Can Reflect Hepatitis B Virus in the Liver and Predict Treatment Response
-
DOI 10.1016/j.cgh.2007.09.005, PII S1542356507008919
-
Chan HL, Wong VW, Tse AM, et al. Serum hepatitis B surface antigen quantitation can reflect hepatitis B virus in the liver and predict treatment response. Clin Gastroenterol Hepatol 2007; 5:1462-1468. (Pubitemid 350181604)
-
(2007)
Clinical Gastroenterology and Hepatology
, vol.5
, Issue.12
, pp. 1462-1468
-
-
Chan, H.L.1
Wong, V.W.2
Tse, A.M.3
Tse, C.4
Chim, A.M.5
Chan, H.6
Wong, G.L.7
Sung, J.J.8
-
21
-
-
65449117946
-
Hepatitis B virus surface antigen levels: A guide to sustained response to peginterferon alfa-2a in HBeAg-negative chronic hepatitis B
-
Brunetto MR, Moriconi F, Bonino F, et al. Hepatitis B virus surface antigen levels: a guide to sustained response to peginterferon alfa-2a in HBeAg-negative chronic hepatitis B. Hepatology 2009; 49:1141-1150.
-
(2009)
Hepatology
, vol.49
, pp. 1141-1150
-
-
Brunetto, M.R.1
Moriconi, F.2
Bonino, F.3
-
22
-
-
77955703978
-
Early on-treatment prediction of response to peginterferon alfa-2b for HBeAg-negative chronic hepatitis B using HbsAg and HBV DNA levels
-
Rijckborst V, Hansen BE, Cakaloglu Y, et al. Early on-treatment prediction of response to peginterferon alfa-2b for HBeAg-negative chronic hepatitis B using HbsAg and HBV DNA levels. Hepatology 2010; 52:454-461.
-
(2010)
Hepatology
, vol.52
, pp. 454-461
-
-
Rijckborst, V.1
Hansen, B.E.2
Cakaloglu, Y.3
-
23
-
-
77956592924
-
Kinetics of hepatitis B surface antigen decline during 3 years of telbivudine treatment in hepatitis B e antigen-positive patients
-
Wursthorn K, Jung M, Riva A, et al. Kinetics of hepatitis B surface antigen decline during 3 years of telbivudine treatment in hepatitis B e antigen-positive patients. Hepatology 2010; 52:1611-1620.
-
(2010)
Hepatology
, vol.52
, pp. 1611-1620
-
-
Wursthorn, K.1
Jung, M.2
Riva, A.3
-
24
-
-
19544391413
-
Lamivudine for patients with chronic hepatitis B and advanced liver disease
-
Liaw YF, Sung JJ, Chow WC, et al. Lamivudine for patients with chronic hepatitis B and advanced liver disease. N Engl J Med 2004; 351:1521-1531.
-
(2004)
N Engl J Med
, vol.351
, pp. 1521-1531
-
-
Liaw, Y.F.1
Sung, J.J.2
Chow, W.C.3
-
25
-
-
0036779279
-
Factors associated with viral breakthrough in lamivudine monoprophylaxis of hepatitis B virus recurrence after liver transplantation
-
Chan HL, Chui AK, Lau WY, et al. Factors associated with viral breakthrough in lamivudine monoprophylaxis of hepatitis B virus recurrence after liver transplantation. J Med Virol 2002; 68:182-187.
-
(2002)
J Med Virol
, vol.68
, pp. 182-187
-
-
Chan, H.L.1
Chui, A.K.2
Lau, W.Y.3
-
26
-
-
0034000310
-
Hepatitis B e antigen-negative chronic hepatitis B in Hong Kong
-
Chan HL, Leung NW, Hussain M, Wong ML, Lok AS. Hepatitis B e antigen-negative chronic hepatitis B in Hong Kong. Hepatology 2000; 31:763-768. (Pubitemid 30118648)
-
(2000)
Hepatology
, vol.31
, Issue.3
, pp. 763-768
-
-
Chan, H.L.Y.1
Leung, N.W.Y.2
Hussain, M.3
Wong, M.L.4
Lok, A.S.E.5
-
27
-
-
77950594817
-
On-treatment serum HBsAg level is predictive of sustained off-treatment virological response to telbivudine in HBeAg-positive chronic hepatitis B patients
-
Cai W, Xie Q, An B, et al. On-treatment serum HBsAg level is predictive of sustained off-treatment virological response to telbivudine in HBeAg-positive chronic hepatitis B patients. J Clin Virol 2010; 48:22-26.
-
(2010)
J Clin Virol
, vol.48
, pp. 22-26
-
-
Cai, W.1
Xie, Q.2
An, B.3
-
28
-
-
77952716572
-
Serum hepatitis B surface antigen and hepatitis B e antigen titers: Disease phase influences correlation with viral load and intrahepatic hepatitis virus markers
-
Thompson AJ, Nguyen T, Iser D, et al. Serum hepatitis B surface antigen and hepatitis B e antigen titers: Disease phase influences correlation with viral load and intrahepatic hepatitis virus markers. Hepatology 2010; 51:1933-1944.
-
(2010)
Hepatology
, vol.51
, pp. 1933-1944
-
-
Thompson, A.J.1
Nguyen, T.2
Iser, D.3
-
29
-
-
77956598865
-
Relationship between serum hepatitis B virus DNA and surface antigen with covalently closed circular DNA in HBeAg-negative patients
-
Lin LY, Wong VW, Zhou HJ, et al. Relationship between serum hepatitis B virus DNA and surface antigen with covalently closed circular DNA in HBeAg-negative patients. J Med Virol 2010; 82:1494-1500.
-
(2010)
J Med Virol
, vol.82
, pp. 1494-1500
-
-
Lin, L.Y.1
Wong, V.W.2
Zhou, H.J.3
-
30
-
-
34548475512
-
Impaired Intrahepatic Hepatitis B Virus Productivity Contributes to Low Viremia in Most HBeAg-Negative Patients
-
DOI 10.1053/j.gastro.2007.06.057, PII S0016508507012899
-
Volz T, Lutgehetmann M, Wachtler P, et al. Impaired intrahepatic hepatitis B virus productivity contributes to low viremia in most HBeAg-negative patients. Gastroenterology 2007; 133:843-852. (Pubitemid 47374140)
-
(2007)
Gastroenterology
, vol.133
, Issue.3
, pp. 843-852
-
-
Volz, T.1
Lutgehetmann, M.2
Wachtler, P.3
Jacob, A.4
Quaas, A.5
Murray, J.M.6
Dandri, M.7
Petersen, J.8
-
31
-
-
77957938721
-
A longitudinal study on the natural history of serum HBsAg changes in chronic hepatitis B
-
Chan HL, Wong VW, Wong GL, Tse CH, Chan HY, Sung JJ. A longitudinal study on the natural history of serum HBsAg changes in chronic hepatitis B. Hepatology 2010; 52:1232-1241.
-
(2010)
Hepatology
, vol.52
, pp. 1232-1241
-
-
Chan, H.L.1
Wong, V.W.2
Wong, G.L.3
Tse, C.H.4
Chan, H.Y.5
Sung, J.J.6
-
32
-
-
20444505037
-
Intrahepatic hepatitis B virus covalently closed circular DNA can be a predictor of sustained response to therapy
-
DOI 10.1053/j.gastro.2005.03.009, PII S0016508505003902
-
Sung JJ, Wong ML, Bowden S, et al. Intrahepatic hepatitis B virus covalently closed circular DNA can be a predictor of sustained response to therapy. Gastroenterology 2005; 128:1890-1897. (Pubitemid 40824700)
-
(2005)
Gastroenterology
, vol.128
, Issue.7
, pp. 1890-1897
-
-
Sung, J.J.Y.1
Wong, M.-L.2
Bowden, S.3
Liew, C.-T.4
Hui, A.Y.5
Wong, V.W.S.6
Leung, N.W.Y.7
Locarnini, S.8
Chan, H.L.Y.9
-
33
-
-
33847410055
-
Prediction of treatment-related HBsAg loss in HBeAg-negative chronic hepatitis B: A clue from serum HBsAg levels
-
Manesis EK, Hadziyannis ES, Angelopoulou OP, Hadziyannis SJ. Prediction of treatment-related HBsAg loss in HBeAg-negative chronic hepatitis B: a clue from serum HBsAg levels. Antivir Ther 2007; 12:73-82. (Pubitemid 46340428)
-
(2007)
Antiviral Therapy
, vol.12
, Issue.1
, pp. 73-82
-
-
Manesis, E.K.1
Hadziyannis, E.S.2
Angelopoulou, O.P.3
Hadziyannis, S.J.4
-
34
-
-
78449281983
-
Serum HBsAg quantification to predict response to peginterferon therapy of e antigen positive chronic hepatitis B
-
Chan HL, Wong VW, Chim AM, Chan HY, Wong GL, Sung JJ. Serum HBsAg quantification to predict response to peginterferon therapy of e antigen positive chronic hepatitis B. Aliment Pharmacol Ther 2010; 32:1323-1331.
-
(2010)
Aliment Pharmacol Ther
, vol.32
, pp. 1323-1331
-
-
Chan, H.L.1
Wong, V.W.2
Chim, A.M.3
Chan, H.Y.4
Wong, G.L.5
Sung, J.J.6
-
35
-
-
65449123444
-
Early serum HBsAg drop: A strong predictor of sustained virological response to pegylated interferon alfa-2a in HBeAg-negative patients
-
Moucari R, Mackiewicz V, Lada O, et al. Early serum HBsAg drop: A strong predictor of sustained virological response to pegylated interferon alfa-2a in HBeAg-negative patients. Hepatology 2009; 49:1151-1157.
-
(2009)
Hepatology
, vol.49
, pp. 1151-1157
-
-
Moucari, R.1
Mackiewicz, V.2
Lada, O.3
-
36
-
-
47649103303
-
A decline in hepatitis B virus surface antigen (HBsAg) predicts clearance, but does not correlate with quantitative HBeAg or HBV DNA levels
-
Wiegand J, Wedemeyer H, Finger A, et al. A decline in hepatitis B virus surface antigen (HBsAg) predicts clearance, but does not correlate with quantitative HBeAg or HBV DNA levels. Antivir Ther 2008; 13:547-554. (Pubitemid 352016717)
-
(2008)
Antiviral Therapy
, vol.13
, Issue.4
, pp. 547-554
-
-
Wiegand, J.1
Wedemeyer, H.2
Finger, A.3
Heidrich, B.4
Rosenau, J.5
Michel, G.6
Bock, C.T.7
Manns, M.P.8
Tillmann, H.L.9
-
37
-
-
70350496577
-
Predictors of treatment response in chronic hepatitis B
-
Wong GL, Chan HL. Predictors of treatment response in chronic hepatitis B. Drugs 2009; 69:2167-2177.
-
(2009)
Drugs
, vol.69
, pp. 2167-2177
-
-
Wong, G.L.1
Chan, H.L.2
|