메뉴 건너뛰기




Volumn 72, Issue 4, 2013, Pages 441-450

Deciphering the role of n-3 polyunsaturated fatty acid-derived lipid mediators in health and disease

Author keywords

DHA; EPA; Resolution of inflammation; Resolvins

Indexed keywords

CD59 ANTIGEN; G PROTEIN COUPLED RECEPTOR; LEUKOTRIENE; MARESIN; OMEGA 3 FATTY ACID; PROSTAGLANDIN; RESOLVIN; UNCLASSIFIED DRUG; ARACHIDONIC ACID; AUTACOID; BIOLOGICAL FACTOR; CYCLOOXYGENASE 2; DOCOSAHEXAENOIC ACID; FORMYLPEPTIDE RECEPTOR LIKE 1; ICOSAPENTAENOIC ACID; LEUKOTRIENE B4; LIPID; LIPOXIN A; LIPOXYGENASE; OMEGA 6 FATTY ACID; POLYUNSATURATED FATTY ACID; PROSTAGLANDIN SYNTHASE; PROSTANOID;

EID: 84893089131     PISSN: 00296651     EISSN: 14752719     Source Type: Journal    
DOI: 10.1017/S0029665113003030     Document Type: Conference Paper
Times cited : (22)

References (78)
  • 1
    • 0015654235 scopus 로고
    • Nutrition classics from the journal of biological chemistry 82: 345-67 1929 A new deficiency disease produced by the rigid exclusion of fat from the diet
    • Burr GO & Burr MM (1973) Nutrition classics from The Journal of Biological Chemistry 82:345-67, 1929. A new deficiency disease produced by the rigid exclusion of fat from the diet. Nutr Rev 31, 248-249.
    • (1973) Nutr Rev , vol.31 , pp. 248-249
    • Burr, G.O.1    Burr, M.M.2
  • 3
    • 33750110432 scopus 로고    scopus 로고
    • Fatty acids as modulators of the immune response
    • Fritsche K (2006) Fatty acids as modulators of the immune response. Annu Rev Nutr 26, 45-73.
    • (2006) Annu Rev Nutr , vol.26 , pp. 45-73
    • Fritsche, K.1
  • 4
    • 0038647764 scopus 로고    scopus 로고
    • Fatty acids, the immune response, and autoimmunity: A question of n-6 essentiality and the balance between n-6 and n-3
    • Harbige LS (2003) Fatty acids, the immune response, and autoimmunity: A question of n-6 essentiality and the balance between n-6 and n-3. Lipids 38, 323-341.
    • (2003) Lipids , vol.38 , pp. 323-341
    • Harbige, L.S.1
  • 5
    • 0023177955 scopus 로고
    • Leukotrienes and lipoxins: Structures, biosyn thesis and biological effects
    • Samuelsson B, Dahlen SE, Lindgren JA, et al. (1987) Leukotrienes and lipoxins: Structures, biosynthesis, and biological effects. Science 237, 1171-1176.
    • (1987) Science , vol.237 , pp. 1171-1176
    • Samuelsson, B.1    Dahlen, S.E.2    Lindgren, J.A.3
  • 6
    • 42649089790 scopus 로고    scopus 로고
    • Resolving inflammation: Dual anti-inflammatory and pro-resolution lipid mediators
    • Serhan CN, Chiang N & Van Dyke TE (2008) Resolving inflammation: Dual anti-inflammatory and pro-resolution lipid mediators. Nat Rev Immunol 8, 349-361.
    • (2008) Nat Rev Immunol , vol.8 , pp. 349-361
    • Serhan, C.N.1    Chiang, N.2    Van Dyke, T.E.3
  • 7
    • 34548412877 scopus 로고    scopus 로고
    • Omega-3 fatty acids and cardiac arrhythmias: Prior studies and recommendations for future research: A report from the national heart lung, and blood institute and office of dietary supplements omega-3 fatty acids and their role in cardiac arrhythmogenesis workshop
    • London B, Albert C, Anderson ME, et al. (2007) Omega-3 fatty acids and cardiac arrhythmias: Prior studies and recommendations for future research: A report from the National Heart, Lung, and Blood Institute and Office Of Dietary Supplements Omega-3 Fatty Acids and their Role in Cardiac Arrhythmogenesis Workshop. Circulation 116, e320-e335.
    • (2007) Circulation , vol.116
    • London, B.1    Albert, C.2    Anderson, M.E.3
  • 8
    • 84873443547 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acids and inflammatory processes: Nutrition or pharmacology?
    • Calder PC (2013) Omega-3 polyunsaturated fatty acids and inflammatory processes: Nutrition or pharmacology? Br J Clin Pharmacol 75, 645-662.
    • (2013) Br J Clin Pharmacol , vol.75 , pp. 645-662
    • Calder, P.C.1
  • 9
    • 0034686664 scopus 로고    scopus 로고
    • Metabolism of highly unsaturated n-3 and n-6 fatty acids
    • Sprecher H (2000) Metabolism of highly unsaturated n-3 and n-6 fatty acids. Biochim Biophys Acta 1486, 219-231.
    • (2000) Biochim Biophys Acta , vol.1486 , pp. 219-231
    • Sprecher, H.1
  • 10
    • 33746625086 scopus 로고    scopus 로고
    • Transgenic mice rich in endogenous omega-3 fatty acids are protected from colitis
    • Hudert CA, Weylandt KH, Lu Y, et al. (2006) Transgenic mice rich in endogenous omega-3 fatty acids are protected from colitis. Proc Natl Acad Sci USA 103, 11276-11281.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 11276-11281
    • Hudert, C.A.1    Weylandt, K.H.2    Lu, Y.3
  • 11
    • 34447119437 scopus 로고    scopus 로고
    • Increased dietary intake of omega-3-polyunsaturated fatty acids reduces pathological retinal angiogenesis
    • Connor KM, SanGiovanni JP, Lofqvist C, et al. (2007) Increased dietary intake of omega-3-polyunsaturated fatty acids reduces pathological retinal angiogenesis. Nat Med 13, 868-873.
    • (2007) Nat Med , vol.13 , pp. 868-873
    • Connor, K.M.1    SanGiovanni, J.P.2    Lofqvist, C.3
  • 12
    • 33747620742 scopus 로고    scopus 로고
    • Melanoma growth is reduced in fat-1 transgenic mice: Impact of omega-6/ omega-3 essential fatty acids
    • Xia S, Lu Y, Wang J, et al. (2006) Melanoma growth is reduced in fat-1 transgenic mice: Impact of omega-6/ omega-3 essential fatty acids. Proc Natl Acad Sci USA 103, 12499-12504.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 12499-12504
    • Xia, S.1    Lu, Y.2    Wang, J.3
  • 14
    • 0037425770 scopus 로고    scopus 로고
    • Association of n-3 polyunsaturated fatty acids with stability of atherosclerotic plaques: A randomised controlled trial
    • Thies F, Garry JM, Yaqoob P, et al. (2003) Association of n-3 polyunsaturated fatty acids with stability of atherosclerotic plaques: A randomised controlled trial. Lancet 361, 477-485.
    • (2003) Lancet , vol.361 , pp. 477-485
    • Thies, F.1    Garry, J.M.2    Yaqoob, P.3
  • 15
    • 79959484739 scopus 로고    scopus 로고
    • N-3 fatty acids in cardiovascular disease
    • De Caterina R (2011) n-3 fatty acids in cardiovascular disease. N Engl J Med 364, 2439-2450.
    • (2011) N Engl J Med , vol.364 , pp. 2439-2450
    • De Caterina, R.1
  • 16
    • 0345109256 scopus 로고    scopus 로고
    • Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin e after myocardial infarction: Results of the gissi-prevenzione trial gruppo italiano per lo studio della sopravvivenza nell'infarto miocardico
    • GISSI-prevenzione Investigators.
    • GISSI-prevenzione Investigators (1999) Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: Results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico. Lancet 354, 447-455.
    • (1999) Lancet , vol.354 , pp. 447-455
  • 17
    • 53049110571 scopus 로고    scopus 로고
    • Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): A randomised, doubleblind, placebo-controlled trial
    • Tavazzi L, Maggioni AP, Marchioli R, et al. (2008) Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): A randomised, doubleblind, placebo-controlled trial. Lancet 372, 1223-1230.
    • (2008) Lancet , vol.372 , pp. 1223-1230
    • Tavazzi, L.1    Maggioni, A.P.2    Marchioli, R.3
  • 18
    • 84861120187 scopus 로고    scopus 로고
    • Role of basic science in the development of new medicines: Examples from the eicosanoid field
    • Samuelsson B (2012) Role of basic science in the development of new medicines: Examples from the eicosanoid field. J Biol Chem 287, 10070-10080.
    • (2012) J Biol Chem , vol.287 , pp. 10070-10080
    • Samuelsson, B.1
  • 19
    • 0036282839 scopus 로고    scopus 로고
    • Microsomal cytochrome P450 and eicosanoid metabolism
    • Capdevila JH, Harris RC & Falck JR (2002) Microsomal cytochrome P450 and eicosanoid metabolism. Cell Mol Life Sci 59, 780-789.
    • (2002) Cell Mol Life Sci , vol.59 , pp. 780-789
    • Capdevila, J.H.1    Harris, R.C.2    Falck, J.R.3
  • 20
    • 4444262310 scopus 로고    scopus 로고
    • Pharmacology and signaling of prostaglandin receptors: Multiple roles in inflammation and immune modulation
    • Hata AN & Breyer RM (2004) Pharmacology and signaling of prostaglandin receptors: Multiple roles in inflammation and immune modulation. Pharmacol Ther 103, 147-166.
    • (2004) Pharmacol Ther , vol.103 , pp. 147-166
    • Hata, A.N.1    Breyer, R.M.2
  • 21
    • 79955670124 scopus 로고    scopus 로고
    • Resolvins and protectins in inflammation resolution
    • Serhan CN & Petasis NA (2011) Resolvins and protectins in inflammation resolution. Chem Rev 111, 5922-5943.
    • (2011) Chem Rev , vol.111 , pp. 5922-5943
    • Serhan, C.N.1    Petasis, N.A.2
  • 22
    • 84864252972 scopus 로고    scopus 로고
    • Resolvins: Anti-inflammatory and proresolving mediators derived from omega-3 polyunsaturated fatty acids
    • Zhang MJ & Spite M (2012) Resolvins: Anti-inflammatory and proresolving mediators derived from omega-3 polyunsaturated fatty acids. Annu Rev Nutr 32, 203-227.
    • (2012) Annu Rev Nutr , vol.32 , pp. 203-227
    • Zhang, M.J.1    Spite, M.2
  • 23
    • 0034675852 scopus 로고    scopus 로고
    • Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing
    • Serhan CN, Clish CB, Brannon J, et al. (2000) Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing. J Exp Med 192, 1197-1204.
    • (2000) J Exp Med , vol.192 , pp. 1197-1204
    • Serhan, C.N.1    Clish, C.B.2    Brannon, J.3
  • 24
    • 0037152160 scopus 로고    scopus 로고
    • Resolvins: A family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals
    • Serhan CN, Hong S, Gronert K, et al. (2002) Resolvins: A family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. J Exp Med 196, 1025-1037.
    • (2002) J Exp Med , vol.196 , pp. 1025-1037
    • Serhan, C.N.1    Hong, S.2    Gronert, K.3
  • 25
    • 12344321136 scopus 로고    scopus 로고
    • Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1
    • Arita M, Bianchini F, Aliberti J, et al. (2005) Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1. J Exp Med 201, 713-722.
    • (2005) J Exp Med , vol.201 , pp. 713-722
    • Arita, M.1    Bianchini, F.2    Aliberti, J.3
  • 26
    • 27544439792 scopus 로고    scopus 로고
    • The contributions of aspirin and microbial oxygenase to the biosynthesis of anti-inflammatory resolvins: Novel oxygenase products from omega-3 polyunsaturated fatty acids
    • Arita M, Clish CB & Serhan CN (2005) The contributions of aspirin and microbial oxygenase to the biosynthesis of anti-inflammatory resolvins: Novel oxygenase products from omega-3 polyunsaturated fatty acids. Biochem Biophys Res Commun 338, 149-157.
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 149-157
    • Arita, M.1    Clish, C.B.2    Serhan, C.N.3
  • 27
    • 79551507279 scopus 로고    scopus 로고
    • Pro-resolving actions and stereoselective biosynthesis of 18S E-series resolvins in human leucocytes and murine inflammation
    • Oh SF, Pillai PS, Recchiuti A, et al. (2011) Pro-resolving actions and stereoselective biosynthesis of 18S E-series resolvins in human leucocytes and murine inflammation. J Clin Invest 121, 569-581.
    • (2011) J Clin Invest , vol.121 , pp. 569-581
    • Oh, S.F.1    Pillai, P.S.2    Recchiuti, A.3
  • 28
    • 84860342237 scopus 로고    scopus 로고
    • Resolvin E2 formation and impact in inflammation resolution
    • Oh SF, Dona M, Fredman G, et al. (2012) Resolvin E2 formation and impact in inflammation resolution. J Immunol 188, 4527-4534.
    • (2012) J Immunol , vol.188 , pp. 4527-4534
    • Oh, S.F.1    Dona, M.2    Fredman, G.3
  • 29
    • 33751020561 scopus 로고    scopus 로고
    • Resolvin E2: Identification and anti-inflammatory actions: Pivotal role of human 5-lipoxygenase in resolvin E series biosynthesis
    • Tjonahen E, Oh SF, Siegelman J, et al. (2006) Resolvin E2: Identification and anti-inflammatory actions: Pivotal role of human 5-lipoxygenase in resolvin E series biosynthesis. Chem Biol 13, 1193-1202.
    • (2006) Chem Biol , vol.13 , pp. 1193-1202
    • Tjonahen, E.1    Oh, S.F.2    Siegelman, J.3
  • 30
    • 84858705961 scopus 로고    scopus 로고
    • Identification and structure determination of novel anti-inflammatory mediator resolvin E3, 17,18-dihydroxyeicosapentaenoic acid
    • Isobe Y, Arita M, Matsueda S, et al. (2012) Identification and structure determination of novel anti-inflammatory mediator resolvin E3, 17,18-dihydroxyeicosapentaenoic acid. J Biol Chem 287, 10525-10534.
    • (2012) J Biol Chem , vol.287 , pp. 10525-10534
    • Isobe, Y.1    Arita, M.2    Matsueda, S.3
  • 31
    • 78549283981 scopus 로고    scopus 로고
    • Novel lipid mediators promote resolution of acute inflammation: Impact of aspirin and statins
    • Spite M & Serhan CN (2010) Novel lipid mediators promote resolution of acute inflammation: Impact of aspirin and statins. Circ Res 107, 1170-1184.
    • (2010) Circ Res , vol.107 , pp. 1170-1184
    • Spite, M.1    Serhan, C.N.2
  • 32
    • 84874302316 scopus 로고    scopus 로고
    • Resolvin D3 and aspirin-Triggered resolvin D3 are potent immunoresolvents
    • Dalli J, Winkler JW, Colas RA, et al. (2013) Resolvin D3 and aspirin-Triggered resolvin D3 are potent immunoresolvents. Chem Biol 20, 188-201.
    • (2013) Chem Biol , vol.20 , pp. 188-201
    • Dalli, J.1    Winkler, J.W.2    Colas, R.A.3
  • 33
    • 0038013967 scopus 로고    scopus 로고
    • Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation
    • Hong S, Gronert K, Devchand PR, et al. (2003) Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation. J Biol Chem 278, 14677-14687.
    • (2003) J Biol Chem , vol.278 , pp. 14677-14687
    • Hong, S.1    Gronert, K.2    Devchand, P.R.3
  • 34
    • 0242290167 scopus 로고    scopus 로고
    • Novel docosanoids inhibit brain ischemia-reperfusion-mediated leucocyte infiltration and pro-inflammatory gene expression
    • Marcheselli VL, Hong S, Lukiw WJ, et al. (2003) Novel docosanoids inhibit brain ischemia-reperfusion-mediated leucocyte infiltration and pro-inflammatory gene expression. J Biol Chem 278, 43807-43817.
    • (2003) J Biol Chem , vol.278 , pp. 43807-43817
    • Marcheselli, V.L.1    Hong, S.2    Lukiw, W.J.3
  • 35
    • 2942625603 scopus 로고    scopus 로고
    • Neuroprotectin D1: A docosahexaenoic acid-derived docosatriene protects human retinal pigment epithelial cells from oxidative stress
    • Mukherjee PK, Marcheselli VL, Serhan CN, et al. (2004) Neuroprotectin D1: A docosahexaenoic acid-derived docosatriene protects human retinal pigment epithelial cells from oxidative stress. Proc Natl Acad Sci USA 101, 8491-8496.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 8491-8496
    • Mukherjee, P.K.1    Marcheselli, V.L.2    Serhan, C.N.3
  • 36
    • 31144469184 scopus 로고    scopus 로고
    • Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: Assignments of dihydroxy-containing docosatrienes
    • Serhan CN, Gotlinger K, Hong S, et al. (2006) Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: Assignments of dihydroxy-containing docosatrienes. J Immunol 176, 1848-1859.
    • (2006) J Immunol , vol.176 , pp. 1848-1859
    • Serhan, C.N.1    Gotlinger, K.2    Hong, S.3
  • 37
    • 70350334135 scopus 로고    scopus 로고
    • Full characterization of PDX, a neuroprotectin/protectin D1 isomer, which inhibits blood platelet aggregation
    • Chen P, Fenet B, Michaud S, et al. (2009) Full characterization of PDX, a neuroprotectin/protectin D1 isomer, which inhibits blood platelet aggregation. FEBS Lett 583, 3478-3484.
    • (2009) FEBS Lett , vol.583 , pp. 3478-3484
    • Chen, P.1    Fenet, B.2    Michaud, S.3
  • 38
    • 60549107724 scopus 로고    scopus 로고
    • Maresins: Novel macrophage mediators with potent antiinflammatory and proresolving actions
    • Serhan CN, Yang R, Martinod K, et al. (2009) Maresins: Novel macrophage mediators with potent antiinflammatory and proresolving actions. J Exp Med 206, 15-23.
    • (2009) J Exp Med , vol.206 , pp. 15-23
    • Serhan, C.N.1    Yang, R.2    Martinod, K.3
  • 39
    • 84879629605 scopus 로고    scopus 로고
    • The novel 13S,14S-epoxy-maresin is converted by human macrophages to maresin1 (MaR1), inhibits leukotriene A4 hydrolase (LTA4H), and shifts macrophage phenotype
    • Dalli J, Zhu M, Vlasenko NA, et al. (2013) The novel 13S,14S-epoxy- maresin is converted by human macrophages to maresin1 (MaR1), inhibits leukotriene A4 hydrolase (LTA4H), and shifts macrophage phenotype. FASEB J.
    • (2013) FASEB J
    • Dalli, J.1    Zhu, M.2    Vlasenko, N.A.3
  • 40
    • 84860899033 scopus 로고    scopus 로고
    • Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain
    • Serhan CN, Dalli J, Karamnov S, et al. (2012) Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain. FASEB J 26, 1755-1765.
    • (2012) FASEB J , vol.26 , pp. 1755-1765
    • Serhan, C.N.1    Dalli, J.2    Karamnov, S.3
  • 42
    • 33846823024 scopus 로고    scopus 로고
    • Resolution of inflammation: State of the art, definitions and terms
    • Serhan CN, Brain SD, Buckley CD, et al. (2007) Resolution of inflammation: State of the art, definitions and terms. FASEB J 21, 325-332.
    • (2007) FASEB J , vol.21 , pp. 325-332
    • Serhan, C.N.1    Brain, S.D.2    Buckley, C.D.3
  • 43
    • 34247505895 scopus 로고    scopus 로고
    • Regulation of intracellular cyclooxygenase levels by gene transcription and protein degradation
    • Kang YJ, Mbonye UR, DeLong CJ, et al. (2007) Regulation of intracellular cyclooxygenase levels by gene transcription and protein degradation. Prog Lipid Res 46, 108-125.
    • (2007) Prog Lipid Res , vol.46 , pp. 108-125
    • Kang, Y.J.1    Mbonye, U.R.2    DeLong, C.J.3
  • 44
    • 0032743539 scopus 로고    scopus 로고
    • The biology of 5-lipoxygenase: Function, structure, and regulatory mechanisms
    • Silverman ES & Drazen JM (1999) The biology of 5-lipoxygenase: Function, structure, and regulatory mechanisms. Proc Assoc Am Physicians 111, 525-536.
    • (1999) Proc Assoc Am Physicians , vol.111 , pp. 525-536
    • Silverman, E.S.1    Drazen, J.M.2
  • 45
    • 0026565597 scopus 로고
    • Specific inflammatory cytokines regulate the expression of human monocyte 15-lipoxygenase
    • Conrad DJ, Kuhn H, Mulkins M, et al. (1992) Specific inflammatory cytokines regulate the expression of human monocyte 15-lipoxygenase. Proc Natl Acad Sci U S A 89, 217-221.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 217-221
    • Conrad, D.J.1    Kuhn, H.2    Mulkins, M.3
  • 46
    • 30044441055 scopus 로고    scopus 로고
    • The docosatriene protectin D1 is produced by TH2 skewing and promotes human T cell apoptosis via lipid raft clustering
    • Ariel A, Li PL, Wang W, et al. (2005) The docosatriene protectin D1 is produced by TH2 skewing and promotes human T cell apoptosis via lipid raft clustering. J Biol Chem 280, 43079-43086.
    • (2005) J Biol Chem , vol.280 , pp. 43079-43086
    • Ariel, A.1    Li, P.L.2    Wang, W.3
  • 47
    • 84867753332 scopus 로고    scopus 로고
    • Specific lipid mediator signatures of human phagocytes: Microparticles stimulate macrophage efferocytosis and pro-resolving mediators
    • Dalli J & Serhan CN (2012) Specific lipid mediator signatures of human phagocytes: Microparticles stimulate macrophage efferocytosis and pro-resolving mediators. Blood 120, e60-e72.
    • (2012) Blood , vol.120
    • Dalli, J.1    Serhan, C.N.2
  • 48
    • 84860250554 scopus 로고    scopus 로고
    • Infection regulates pro-resolving mediators that lower antibiotic requirements
    • Chiang N, Fredman G, Backhed F, et al. (2012) Infection regulates pro-resolving mediators that lower antibiotic requirements. Nature 484, 524-528.
    • (2012) Nature , vol.484 , pp. 524-528
    • Chiang, N.1    Fredman, G.2    Backhed, F.3
  • 49
    • 84875753800 scopus 로고    scopus 로고
    • The lipid mediator protectin d1 inhibits influenza virus replication and improves severe influenza
    • Morita M, Kuba K, Ichikawa A, et al. (2013) The lipid mediator protectin d1 inhibits influenza virus replication and improves severe influenza. Cell 153, 112-125.
    • (2013) Cell , vol.153 , pp. 112-125
    • Morita, M.1    Kuba, K.2    Ichikawa, A.3
  • 50
    • 70350678971 scopus 로고    scopus 로고
    • Resolvin D2 is a potent regulator of leucocytes and controls microbial sepsis
    • Spite M, Norling LV, Summers L, et al. (2009) Resolvin D2 is a potent regulator of leucocytes and controls microbial sepsis. Nature 461, 1287-1291.
    • (2009) Nature , vol.461 , pp. 1287-1291
    • Spite, M.1    Norling, L.V.2    Summers, L.3
  • 51
    • 84866295321 scopus 로고    scopus 로고
    • Resolvin E1 promotes phagocytosis-induced neutrophil apoptosis and accelerates resolution of pulmonary inflammation
    • El Kebir D, Gjorstrup P & Filep JG (2012) Resolvin E1 promotes phagocytosis-induced neutrophil apoptosis and accelerates resolution of pulmonary inflammation. Proc Natl Acad Sci USA 109, 14983-14988.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 14983-14988
    • El Kebir, D.1    Gjorstrup, P.2    Filep, J.G.3
  • 52
    • 34250357688 scopus 로고    scopus 로고
    • Resolvin E1 and protectin D1 activate inflammation-resolution programmes
    • Schwab JM, Chiang N, Arita M, et al. (2007) Resolvin E1 and protectin D1 activate inflammation-resolution programmes. Nature 447, 869-874.
    • (2007) Nature , vol.447 , pp. 869-874
    • Schwab, J.M.1    Chiang, N.2    Arita, M.3
  • 53
    • 33750112087 scopus 로고    scopus 로고
    • Apoptotic neutrophils and T cells sequester chemokines during immune response resolution through modulation of CCR5 expression
    • Ariel A, Fredman G, Sun YP, et al. (2006) Apoptotic neutrophils and T cells sequester chemokines during immune response resolution through modulation of CCR5 expression. Nat Immunol 7, 1209-1216.
    • (2006) Nat Immunol , vol.7 , pp. 1209-1216
    • Ariel, A.1    Fredman, G.2    Sun, Y.P.3
  • 54
    • 35248868413 scopus 로고    scopus 로고
    • Resolvin E1 promotes mucosal surface clearance of neutrophils: A new paradigm for inflammatory resolution
    • Campbell EL, Louis NA, Tomassetti SE, et al. (2007) Resolvin E1 promotes mucosal surface clearance of neutrophils: A new paradigm for inflammatory resolution. FASEB J 21, 3162-3170.
    • (2007) FASEB J , vol.21 , pp. 3162-3170
    • Campbell, E.L.1    Louis, N.A.2    Tomassetti, S.E.3
  • 55
    • 76549124239 scopus 로고    scopus 로고
    • Resolvin D1 binds human phagocytes with evidence for proresolving receptors
    • Krishnamoorthy S, Recchiuti A, Chiang N, et al. (2010) Resolvin D1 binds human phagocytes with evidence for proresolving receptors. Proc Natl Acad Sci USA 107, 1660-1665.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 1660-1665
    • Krishnamoorthy, S.1    Recchiuti, A.2    Chiang, N.3
  • 56
    • 77449097856 scopus 로고    scopus 로고
    • Resolvin E1 receptor activation signals phosphorylation and phagocytosis
    • Ohira T, Arita M, Omori K, et al. (2010) Resolvin E1 receptor activation signals phosphorylation and phagocytosis. J Biol Chem 285, 3451-3461.
    • (2010) J Biol Chem , vol.285 , pp. 3451-3461
    • Ohira, T.1    Arita, M.2    Omori, K.3
  • 57
    • 84872179280 scopus 로고    scopus 로고
    • Resolvin E1 and chemokine-like receptor 1 mediate bone preservation
    • Gao L, Faibish D, Fredman G, et al. (2013) Resolvin E1 and chemokine-like receptor 1 mediate bone preservation. J Immunol 190, 689-694.
    • (2013) J Immunol , vol.190 , pp. 689-694
    • Gao, L.1    Faibish, D.2    Fredman, G.3
  • 58
    • 50949126869 scopus 로고    scopus 로고
    • Resolvin E1, an EPA-derived mediator in whole blood, selectively counter regulates leukocytes and platelets
    • Dona M, Fredman G, Schwab JM, et al. (2008) Resolvin E1, an EPA-derived mediator in whole blood, selectively counter regulates leukocytes and platelets. Blood 112, 848-855.
    • (2008) Blood , vol.112 , pp. 848-855
    • Dona, M.1    Fredman, G.2    Schwab, J.M.3
  • 59
    • 77957698891 scopus 로고    scopus 로고
    • Resolvin E1 regulates adenosine diphosphate activation of human platelets
    • Fredman G, Van Dyke TE & Serhan CN (2010) Resolvin E1 regulates adenosine diphosphate activation of human platelets. Arterioscler Thromb Vasc Biol 30, 2005-2013.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 2005-2013
    • Fredman, G.1    Van Dyke, T.E.2    Serhan, C.N.3
  • 60
    • 33947269798 scopus 로고    scopus 로고
    • Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23 to regulate inflammation
    • Arita M, Ohira T, Sun YP, et al. (2007) Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23 to regulate inflammation. J Immunol 178, 3912-3917.
    • (2007) J Immunol , vol.178 , pp. 3912-3917
    • Arita, M.1    Ohira, T.2    Sun, Y.P.3
  • 61
    • 84860248492 scopus 로고    scopus 로고
    • Resolvin D1 receptor stereoselectivity and regulation of inflammation and proresolving microRNAs
    • Krishnamoorthy S, Recchiuti A, Chiang N, et al. (2012) Resolvin D1 receptor stereoselectivity and regulation of inflammation and proresolving microRNAs. Am J Pathol 180, 2018-2027.
    • (2012) Am J Pathol , vol.180 , pp. 2018-2027
    • Krishnamoorthy, S.1    Recchiuti, A.2    Chiang, N.3
  • 62
    • 84864280040 scopus 로고    scopus 로고
    • Resolvin D1 limits polymorphonuclear leukocyte recruitment to inflammatory loci: Receptor-dependent actions
    • Norling LV, Dalli J, Flower RJ, et al. (2012) Resolvin D1 limits polymorphonuclear leukocyte recruitment to inflammatory loci: Receptor-dependent actions. Arterioscler Thromb Vasc Biol 32, 1970-1978.
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , pp. 1970-1978
    • Norling, L.V.1    Dalli, J.2    Flower, R.J.3
  • 63
    • 73949090946 scopus 로고    scopus 로고
    • Neuroprotectin D1/protectin D1 stereoselective and specific binding with human retinal pigment epithelial cells and neutrophils
    • Marcheselli VL, Mukherjee PK, Arita M, et al. (2010) Neuroprotectin D1/protectin D1 stereoselective and specific binding with human retinal pigment epithelial cells and neutrophils. Prostaglandins Leukot Essent Fatty Acids 82, 27-34.
    • (2010) Prostaglandins Leukot Essent Fatty Acids , vol.82 , pp. 27-34
    • Marcheselli, V.L.1    Mukherjee, P.K.2    Arita, M.3
  • 64
    • 84873050854 scopus 로고    scopus 로고
    • Proresolution therapy for the treatment of delayed healing of diabetic wounds
    • Tang Y, Zhang MJ, Hellmann J, et al. (2013) Proresolution therapy for the treatment of delayed healing of diabetic wounds. Diabetes 62, 618-627.
    • (2013) Diabetes , vol.62 , pp. 618-627
    • Tang, Y.1    Zhang, M.J.2    Hellmann, J.3
  • 65
    • 84872104079 scopus 로고    scopus 로고
    • Resolvin D2 prevents secondary thrombosis and necrosis in a mouse burn wound model
    • Bohr S, Patel SJ, Sarin D, et al. (2013) Resolvin D2 prevents secondary thrombosis and necrosis in a mouse burn wound model. Wound Repair Regen 21, 35-43.
    • (2013) Wound Repair Regen , vol.21 , pp. 35-43
    • Bohr, S.1    Patel, S.J.2    Sarin, D.3
  • 66
    • 84878767354 scopus 로고    scopus 로고
    • Resolvin D2 restores neutrophil directionality and improves survival after burns
    • Kurihara T, Jones CN, Yu YM, et al. (2013) Resolvin D2 restores neutrophil directionality and improves survival after burns. FASEB J 6, 2270-2281.
    • (2013) FASEB J , vol.6 , pp. 2270-2281
    • Kurihara, T.1    Jones, C.N.2    Yu, Y.M.3
  • 67
    • 79956200036 scopus 로고    scopus 로고
    • Cutting edge: Humanized nano-proresolving medicines mimic inflammation-resolution and enhance wound healing
    • Norling LV, Spite M, Yang R, et al. (2011) Cutting edge: Humanized nano-proresolving medicines mimic inflammation-resolution and enhance wound healing. J Immunol 186, 5543-5547.
    • (2011) J Immunol , vol.186 , pp. 5543-5547
    • Norling, L.V.1    Spite, M.2    Yang, R.3
  • 68
    • 84865408390 scopus 로고    scopus 로고
    • Resolvin D1 and resolvin D2 govern local inflammatory tone in obese fat
    • Claria J, Dalli J, Yacoubian S, et al. (2012) Resolvin D1 and resolvin D2 govern local inflammatory tone in obese fat. J Immunol 189, 2597-2605.
    • (2012) J Immunol , vol.189 , pp. 2597-2605
    • Claria, J.1    Dalli, J.2    Yacoubian, S.3
  • 69
    • 84867940403 scopus 로고    scopus 로고
    • New insights into the role of macrophages in adipose tissue inflammation and fatty liver disease: Modulation by endogenous omega-3 fatty acid-derived lipid mediators
    • Claria J, Gonzalez-Periz A, Lopez-Vicario C, et al. (2011) New insights into the role of macrophages in adipose tissue inflammation and fatty liver disease: Modulation by endogenous omega-3 fatty acid-derived lipid mediators. Front Immunol 2, 49.
    • (2011) Front Immunol , vol.2 , pp. 49
    • Claria, J.1    Gonzalez-Periz, A.2    Lopez-Vicario, C.3
  • 71
    • 67649363782 scopus 로고    scopus 로고
    • Obesity-induced insulin resistance and hepatic steatosis are alleviated by omega-3 fatty acids: A role for resolvins and protectins
    • Gonzalez-Periz A, Horrillo R, Ferre N, et al. (2009) Obesity-induced insulin resistance and hepatic steatosis are alleviated by omega-3 fatty acids: A role for resolvins and protectins. FASEB J 23, 1946-1957.
    • (2009) FASEB J , vol.23 , pp. 1946-1957
    • Gonzalez-Periz, A.1    Horrillo, R.2    Ferre, N.3
  • 72
    • 84866978271 scopus 로고    scopus 로고
    • Resolvins D1 D2, and other mediators of self-limited resolution of inflammation in human blood following n-3 fatty acid supplementation
    • Mas E, Croft KD, Zahra P, et al. (2012) Resolvins D1, D2, and other mediators of self-limited resolution of inflammation in human blood following n-3 fatty acid supplementation. Clin Chem 58, 1476-1484.
    • (2012) Clin Chem , vol.58 , pp. 1476-1484
    • Mas, E.1    Croft, K.D.2    Zahra, P.3
  • 73
    • 33846001661 scopus 로고    scopus 로고
    • Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness
    • Levy BD, Kohli P, Gotlinger K, et al. (2007) Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness. J Immunol 178, 496-502.
    • (2007) J Immunol , vol.178 , pp. 496-502
    • Levy, B.D.1    Kohli, P.2    Gotlinger, K.3
  • 74
    • 77957328862 scopus 로고    scopus 로고
    • Aspirin-Triggered lipoxin and resolvin E1 modulate vascular smooth muscle phenotype and correlate with peripheral atherosclerosis
    • Ho KJ, Spite M, Owens CD, et al. (2010) Aspirin-Triggered lipoxin and resolvin E1 modulate vascular smooth muscle phenotype and correlate with peripheral atherosclerosis. Am J Pathol 177, 2116-2123.
    • (2010) Am J Pathol , vol.177 , pp. 2116-2123
    • Ho, K.J.1    Spite, M.2    Owens, C.D.3
  • 75
    • 0033924902 scopus 로고    scopus 로고
    • Aspirin-Tolerant asthmatics generate more lipoxins than aspirin-intolerant asthmatics
    • Sanak M, Levy BD, Clish CB, et al. (2000) Aspirin-Tolerant asthmatics generate more lipoxins than aspirin-intolerant asthmatics. Eur Respir J 16, 44-49.
    • (2000) Eur Respir J , vol.16 , pp. 44-49
    • Sanak, M.1    Levy, B.D.2    Clish, C.B.3
  • 76
    • 82455192824 scopus 로고    scopus 로고
    • Emerging roles of resolvins in the resolution of inflammation and pain
    • Ji RR, Xu ZZ, Strichartz G, et al. (2011) Emerging roles of resolvins in the resolution of inflammation and pain. Trends Neurosci 34, 599-609.
    • (2011) Trends Neurosci , vol.34 , pp. 599-609
    • Ji, R.R.1    Xu, Z.Z.2    Strichartz, G.3
  • 77
    • 83455177641 scopus 로고    scopus 로고
    • Resolvin D2 is a potent endogenous inhibitor for transient receptor potential subtype V1/A1, inflammatory pain, and spinal cord synaptic plasticity in mice: Distinct roles of resolvin D1, D2, and E1
    • Park CK, Xu ZZ, Liu T, et al. (2011) Resolvin D2 is a potent endogenous inhibitor for transient receptor potential subtype V1/A1, inflammatory pain, and spinal cord synaptic plasticity in mice: Distinct roles of resolvin D1, D2, and E1. J Neurosci 31, 18433-18438.
    • (2011) J Neurosci , vol.31 , pp. 18433-18438
    • Park, C.K.1    Xu, Z.Z.2    Liu, T.3
  • 78
    • 77952237425 scopus 로고    scopus 로고
    • Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions
    • Xu ZZ, Zhang L, Liu T, et al. (2010) Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions. Nat Med 16, 592-597.
    • (2010) Nat Med , vol.16 , pp. 592-597
    • Xu, Z.Z.1    Zhang, L.2    Liu, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.