Resolvin E2 formation and impact in inflammation resolution

Journal of Immunology

Volumn 188, Issue 9, 2012, Pages 4527-4534

  Oh, Sungwhan F ^a,c   Dona, Maria ^a,d   Fredman, Gabrielle ^a,e   Krishnamoorthy, Sriram ^a,f   Irimia, Daniel ^b   Serhan, Charles N ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d HARVARD SCHOOL OF DENTAL MEDICINE   (United States)

^e Columbia University ^*  (United States)

^f BIOGEN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; G PROTEIN COUPLED RECEPTOR; HUMAN LEUKOCYTE INTEGRIN; ICOSAPENTAENOIC ACID; INTEGRIN; POLYUNSATURATED FATTY ACID; RESOLVIN E2 FATTY ACID; UNCLASSIFIED DRUG;

ARTICLE; CHEMOTAXIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; INFLAMMATION; NEUTROPHIL; PERITONITIS; PHAGOCYTOSIS; PRIORITY JOURNAL;

ANIMALS; CHEMOTAXIS; DOWN-REGULATION; EICOSAPENTAENOIC ACID; FEMALE; HUMANS; IMMUNITY, INNATE; INFLAMMATION; INTEGRINS; MALE; MICE; NEUTROPHILS; PHAGOCYTOSIS; PLATELET ACTIVATING FACTOR;

EID: 84860342237     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1103652     Document Type: Article

References (51)

1. Kumar, V., A. K. Abbas, N. Fausto, S. L. Robbins, and R. S. Cotran. 2005. Robbins and Cotran Pathologic Basis of Disease. Elsevier Saunders, Philadelphia.
2. Serhan, C. N., and J. Savill. 2005. Resolution of inflammation: the beginning programs the end. Nat. Immunol. 6: 1191-1197. (Pubitemid 43045627)
3. Libby, P., Y. Okamoto, V. Z. Rocha, and E. Folco. 2010. Inflammation in atherosclerosis: transition from theory to practice. Circ. J. 74: 213-220.
4. Stoll, G., C. Kleinschnitz, and B. Nieswandt. 2010. Combating innate inflammation: a new paradigm for acute treatment of stroke? Ann. N. Y. Acad. Sci. 1207: 149-154.
5. Tabas, I. 2010. Macrophage death and defective inflammation resolution in atherosclerosis. Nat. Rev. Immunol. 10: 36-46.
6. Lawrence, T., and D. W. Gilroy. 2007. Chronic inflammation: a failure of resolution? Int. J. Exp. Pathol. 88: 85-94. (Pubitemid 46570075)
7. Serhan, C. N., C. B. Clish, J. Brannon, S. P. Colgan, N. Chiang, and K. Gronert. 2000. Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing. J. Exp. Med. 192: 1197-1204.
8. Bannenberg, G. L., N. Chiang, A. Ariel, M. Arita, E. Tjonahen, K. H. Gotlinger, S. Hong, and C. N. Serhan. 2005. Molecular circuits of resolution: formation and actions of resolvins and protectins. J. Immunol. 174: 4345-4355. (Pubitemid 40396017)
9. Levy, B. D., C. B. Clish, B. Schmidt, K. Gronert, and C. N. Serhan. 2001. Lipid mediator class switching during acute inflammation: signals in resolution. Nat. Immunol. 2: 612-619. (Pubitemid 32677628)
10. Spite, M., and C. N. Serhan. 2010. Novel lipid mediators promote resolution of acute inflammation: impact of aspirin and statins. Circ. Res. 107: 1170-1184.
11. Gilroy, D. W. 2010. Eicosanoids and the endogenous control of acute inflammatory resolution. Int. J. Biochem. Cell Biol. 42: 524-528.
12. Campbell, E. L., C. F. MacManus, D. J. Kominsky, S. Keely, L. E. Glover, B. E. Bowers, M. Scully, W. J. Bruyninckx, and S. P. Colgan. 2010. Resolvin E1-induced intestinal alkaline phosphatase promotes resolution of inflammation through LPS detoxification. Proc. Natl. Acad. Sci. USA 107: 14298-14303.
13. Hasturk, H., A. Kantarci, T. Ohira, M. Arita, N. Ebrahimi, N. Chiang, N. A. Petasis, B. D. Levy, C. N. Serhan, and T. E. Van Dyke. 2006. RvE1 protects from local inflammation and osteoclast-mediated bone destruction in periodontitis. FASEB J. 20: 401-403. (Pubitemid 46671185)
14. Yamada, T., Y. Tani, H. Nakanishi, R. Taguchi, M. Arita, and H. Arai. 2011. Eosinophils promote resolution of acute peritonitis by producing proresolving mediators in mice. FASEB J. 25: 561-568.
15. Krishnamoorthy, S., A. Recchiuti, N. Chiang, S. Yacoubian, C. H. Lee, R. Yang, N. A. Petasis, and C. N. Serhan. 2010. Resolvin D1 binds human phagocytes with evidence for proresolving receptors. Proc. Natl. Acad. Sci. USA 107: 1660-1665.
16. Hong, S., T. F. Porter, Y. Lu, S. F. Oh, P. S. Pillai, and C. N. Serhan. 2008. Resolvin E1 metabolome in local inactivation during inflammation- resolution. J. Immunol. 180: 3512-3519.
17. Oh, S. F., P. S. Pillai, A. Recchiuti, R. Yang, and C. N. Serhan. 2011. Proresolving actions and stereoselective biosynthesis of 18S E-series resolvins in human leukocytes and murine inflammation. J. Clin. Invest. 121: 569-581.
18. Tjonahen, E., S. F. Oh, J. Siegelman, S. Elangovan, K. B. Percarpio, S. Hong, M. Arita, and C. N. Serhan. 2006. Resolvin E2: identification and antiinflammatory actions: pivotal role of human 5-lipoxygenase in resolvin E series biosynthesis. Chem. Biol. 13: 1193-1202. (Pubitemid 44750731)
19. Ogawa, S., D. Urabe, Y. Yokokura, H. Arai, M. Arita, and M. Inoue. 2009. Total synthesis and bioactivity of resolvin E2. Org. Lett. 11: 3602-3605.
20. Yang, R., N. Chiang, S. F. Oh, and C. N. Serhan. 2011. Metabolomics-lipidomics of eicosanoids and docosanoids generated by phagocytes. Curr. Protoc. Immunol. 95: 14.26.11-14.26.26.
21. Dona, M., G. Fredman, J. M. Schwab, N. Chiang, M. Arita, A. Goodarzi, G. Cheng, U. H. von Andrian, and C. N. Serhan. 2008. Resolvin E1, an EPA-derived mediator in whole blood, selectively counterregulates leukocytes and platelets. Blood 112: 848-855.
22. Serhan, C. N., S. Hong, K. Gronert, S. P. Colgan, P. R. Devchand, G. Mirick, and R.-L. Moussignac. 2002. Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. J. Exp. Med. 196: 1025-1037. (Pubitemid 35231761)
23. Kasuga, K., R. Yang, T. F. Porter, N. Agrawal, N. A. Petasis, D. Irimia, M. Toner, and C. N. Serhan. 2008. Rapid appearance of resolvin precursors in inflammatory exudates: novel mechanisms in resolution. J. Immunol. 181: 8677-8687.
24. Irimia, D., S.-Y. Liu, W. G. Tharp, A. Samadani, M. Toner, and M. C. Poznansky. 2006. Microfluidic system for measuring neutrophil migratory responses to fast switches of chemical gradients. Lab Chip 6: 191-198.
25. Carbo, C., D. Duerschmied, T. Goerge, H. Hattori, J. Sakai, S. M. Cifuni, G. C. White, II, M. Chrzanowska-Wodnicka, H. R. Luo, and D. D. Wagner. 2010. Integrin-independent role of CalDAG-GEFI in neutrophil chemotaxis. J. Leukoc. Biol. 88: 313-319.
26. Taketo, M., A. C. Schroeder, L. E. Mobraaten, K. B. Gunning, G. Hanten, R. R. Fox, T. H. Roderick, C. L. Stewart, F. Lilly, C. T. Hansen, and P. A. Overbeek. 1991. FVB/N: an inbred mouse strain preferable for transgenic analyses. Proc. Natl. Acad. Sci. USA 88: 2065-2069. (Pubitemid 21916354)
27. Knott, M. L., S. P. Hogan, H. Wang, K. I. Matthaei, and L. A. Dent. 2009. FVB/N mice are highly resistant to primary infection with Nippostrongylus brasiliensis. Parasitology 136: 93-106.
28. Mähler, M., C. Janke, S. Wagner, and H. J. Hedrich. 2002. Differential susceptibility of inbred mouse strains to Helicobacter pylori infection. Scand. J. Gastroenterol. 37: 267-278. (Pubitemid 34194812)
29. Schwab, J. M., N. Chiang, M. Arita, and C. N. Serhan. 2007. Resolvin E1 and protectin D1 activate inflammation-resolution programmes. Nature 447: 869-874. (Pubitemid 46920139)
30. Arita, M., T. Ohira, Y. P. Sun, S. Elangovan, N. Chiang, and C. N. Serhan. 2007. Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23 to regulate inflammation. J. Immunol. 178: 3912-3917. (Pubitemid 46417661)
31. Arita, M., F. Bianchini, J. Aliberti, A. Sher, N. Chiang, S. Hong, R. Yang, N. A. Petasis, and C. N. Serhan. 2005. Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1. J. Exp. Med. 201: 713-722. (Pubitemid 40395117)
32. 4 receptor. J. Exp. Med. 180: 253-260. (Pubitemid 24181074)
33. Ohira, T., M. Arita, K. Omori, A. Recchiuti, T. E. Van Dyke, and C. N. Serhan. 2010. Resolvin E1 receptor activation signals phosphorylation and phagocytosis. J. Biol. Chem. 285: 3451-3461.
34. Hong, S., E. Tjonahen, E. L. Morgan, Y. Lu, C. N. Serhan, and A. F. Rowley. 2005. Rainbow trout (Oncorhynchus mykiss) brain cells biosynthesize novel docosahexaenoic acid-derived resolvins and protectins-Mediator lipidomic analysis. Prostaglandins Other Lipid Mediat. 78: 107-116. (Pubitemid 41636836)
35. Oh, S. F., T. W. Vickery, and C. N. Serhan. 2011. Chiral lipidomics of E-series resolvins: aspirin and the biosynthesis of novel mediators. Biochim. Biophys. Acta 1811: 737-747.
36. Serhan, C. N., and N. Chiang. 2008. Endogenous pro-resolving and anti-inflammatory lipid mediators: a new pharmacologic genus. Br. J. Pharmacol. 153(Suppl 1): S200-S215. (Pubitemid 351340979)
37. Hung, N. D., M. R. Kim, and D.-E. Sok. 2011. Oral administration of 2-docosahexaenoyl lysophosphatidylcholine displayed anti-inflammatory effects on zymosan A-induced peritonitis. Inflammation 34: 147-160.
38. Krishnamurthy, V. R., A. Dougherty, C. A. Haller, and E. L. Chaikof. 2011. Total synthesis and bioactivity of 18(R)-hydroxyeicosapentaenoic acid. J. Org. Chem. 76: 5433-5437.
39. Psychogios, N., D. D. Hau, J. Peng, A. C. Guo, R. Mandal, S. Bouatra, I. Sinelnikov, R. Krishnamurthy, R. Eisner, B. Gautam, et al. 2011. The human serum metabolome. PLoS ONE 6: e16957.
40. Raatz, S. K., M. Y. Golovko, S. A. Brose, T. A. Rosenberger, G. S. Burr, W. R. Wolters, and M. J. Picklo, Sr. 2011. Baking reduces prostaglandin, resolvin, and hydroxy-fatty acid content of farm-raised Atlantic salmon (Salmo salar). J. Agric. Food Chem. 59: 11278-11286.
41. De Caterina, R. 2011. n-3 fatty acids in cardiovascular disease. N. Engl. J. Med. 364: 2439-2450.
42. Serhan, C. N., S. D. Brain, C. D. Buckley, D. W. Gilroy, C. Haslett, L. A. J. O'Neill, M. Perretti, A. G. Rossi, and J. L. Wallace. 2007. Resolution of inflammation: state of the art, definitions and terms. FASEB J. 21: 325-332. (Pubitemid 46213480)
43. Serhan, C. N. 2011. The resolution of inflammation: the devil in the flask and in the details. FASEB J. 25: 1441-1448.
44. Maderna, P., S. Yona, M. Perretti, and C. Godson. 2005. Modulation of phagocytosis of apoptotic neutrophils by supernatant from dexamethasonetreated macrophages and annexin-derived peptide Ac(2-26). J. Immunol. 174: 3727-3733. (Pubitemid 40354084)
45. Perretti, M., and J. Dalli. 2009. Exploiting the Annexin A1 pathway for the development of novel anti-inflammatory therapeutics. Br. J. Pharmacol. 158: 936-946.
46. Colgan, S. P., and H. K. Eltzschig. 2012. Adenosine and hypoxia-inducible factor signaling in intestinal injury and recovery. Annu. Rev. Physiol. 74: 7.1-7.23.
47. Haskó, G., J. Linden, B. Cronstein, and P. Pacher. 2008. Adenosine receptors: therapeutic aspects for inflammatory and immune diseases. Nat. Rev. Drug Discov. 7: 759-770.
48. Rosenberger, P., J. M. Schwab, V. Mirakaj, E. Masekowsky, A. Mager, J. C. Morote-Garcia, K. Unertl, and H. K. Eltzschig. 2009. Hypoxia-inducible factor-dependent induction of netrin-1 dampens inflammation caused by hypoxia. Nat. Immunol. 10: 195-202.
49. Eltzschig, H. K., and P. Carmeliet. 2011. Hypoxia and inflammation. N. Engl. J. Med. 364: 656-665.
50. Campbell, E. L., C. N. Serhan, and S. P. Colgan. 2011. Antimicrobial aspects of inflammatory resolution in the mucosa: a role for proresolving mediators. J. Immunol. 187: 3475-3481.
51. Recchiuti, A., S. Krishnamoorthy, G. Fredman, N. Chiang, and C. N. Serhan. 2011. MicroRNAs in resolution of acute inflammation: identification of novel resolvin D1-miRNA circuits. FASEB J. 25: 544-560.