Potential small-molecule activators of caspase-7 identified using yeast-based caspase-3 and -7 screening assays

European Journal of Pharmaceutical Sciences

Volumn 54, Issue 1, 2014, Pages 8-16

  Pereira, Clara ^a   Lopes Rodrigues, Vanessa ^a,b   Coutinho, Isabel ^a   Neves, Marta P ^a,b   Lima, Raquel T ^a,b   Pinto, Madalena ^a,b   Cidade, Honorina ^a,b   Vasconcelos, M Helena ^a   Saraiva, Lucília ^a  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

Author keywords

Caspase 3; Caspase 7; Caspase 7 activators; Prenylated flavonoids; Target based screening assays; Yeast

Indexed keywords

3 HYDROXY 7 GERANYLOXYFLAVONE; 5,6 DIHYDROXY 7 PRENYLOXYFLAVONE; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 7; DUAL SPECIFICITY PHOSPHATASE 2; ENZYME ACTIVATOR; UNCLASSIFIED DRUG;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BREAST ADENOCARCINOMA; CELL ASSAY; CELL STRAIN HL 60; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG SCREENING; ENZYME ACTIVITY; FUNGAL STRAIN; FUNGUS GROWTH; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; SACCHAROMYCES CEREVISIAE; YEAST CELL;

CASPASE-3; CASPASE-7; CASPASE-7 ACTIVATORS; PRENYLATED FLAVONOIDS; TARGET-BASED SCREENING ASSAYS; YEAST;

BIOLOGICAL ASSAY; CASPASE 3; CASPASE 7; CELL PROLIFERATION; CELL SURVIVAL; ENZYME ACTIVATION; ENZYME ACTIVATORS; ETOPOSIDE; FLAVONES; HL-60 CELLS; HUMANS; MCF-7 CELLS; SACCHAROMYCES CEREVISIAE;

EID: 84893050056     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2013.12.017     Document Type: Article

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