Properties of human brain sodium channel α-subunits expressed in HEK293 cells and their modulation by carbamazepine, phenytoin and lamotrigine

British Journal of Pharmacology

Volumn 171, Issue 4, 2014, Pages 1054-1067

  Qiao, Xin ^a   Sun, Guangchun ^a,c   Clare, Jeffrey J ^b   Werkman, Taco R ^a   Wadman, Wytse J ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b Eaton Pharma Consulting   (United Kingdom)

^c FUDAN UNIVERSITY   (China)

Author keywords

antiepileptic drug; carbamazepine; epilepsy; lamotrigine; phenytoin; sodium channel

Indexed keywords

CARBAMAZEPINE; LAMOTRIGINE; PHENYTOIN; SODIUM CHANNEL NAV1.1; SODIUM CHANNEL NAV1.2; SODIUM CHANNEL NAV1.3; SODIUM CHANNEL NAV1.6;

ARTICLE; BIOPHYSICS; CELL STRAIN HEK293; CELLULAR DISTRIBUTION; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG PROTEIN BINDING; HUMAN; HUMAN CELL; NERVE CELL EXCITABILITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; STEADY STATE;

ANTIEPILEPTIC DRUG; CARBAMAZEPINE; EPILEPSY; LAMOTRIGINE; PHENYTOIN; SODIUM CHANNEL;

ANTICONVULSANTS; BRAIN; CARBAMAZEPINE; HEK293 CELLS; HUMANS; PHENYTOIN; PROTEIN SUBUNITS; SODIUM CHANNELS; TRIAZINES; VOLTAGE-GATED SODIUM CHANNEL BLOCKERS;

EID: 84893039473     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12534     Document Type: Article

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