Beyond Islet Transplantation in Diabetes Cell Therapy: From Embryonic Stem Cells to Transdifferentiation of Adult Cells

Transplantation Proceedings

Volumn 45, Issue 5, 2013, Pages 2019-2024

  Gioviale, M C ^a   Bellavia, M ^a   Damiano, G ^a   Lo Monte, A I ^a  

^a UNIVERSITY OF PALERMO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOSE DERIVED STEM CELL; ARTICLE; CELL REGENERATION; CELL TRANSDIFFERENTIATION; CORD BLOOD STEM CELL TRANSPLANTATION; DIABETES MELLITUS; EMBRYONIC STEM CELL; HEMATOPOIETIC STEM CELL; HUMAN; NONHUMAN; PANCREAS; PANCREAS ISLET BETA CELL; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; ADULT; CELL DIFFERENTIATION; CYTOLOGY; REVIEW;

ADULT; CELL DIFFERENTIATION; DIABETES MELLITUS; EMBRYONIC STEM CELLS; HUMANS; ISLETS OF LANGERHANS TRANSPLANTATION;

EID: 84892985085     PISSN: 00411345     EISSN: 18732623     Source Type: Journal    
DOI: 10.1016/j.transproceed.2013.01.076     Document Type: Article

References (69)

1. Gruessner, A.C., 2011 update on pancreas transplantation: comprehensive trend analysis of 25,000 cases followed up over the course of twenty-four years at the International Pancreas Transplant Registry (IPTR). Rev Diabet Stud 13 (2011), 6–16.
2. Ciancio, G., Lo Monte, A., Buscemi, G., et al. Use of tacrolimus and mycophenolate mofetil as induction and maintenance in simultaneous pancreas-kidney transplantation. Transplant International 13 (2000), S191–S194.
3. Lo Monte, A.I., Ciancio, G., Burke, G., et al. The new immunosuppressive era. Ann Ital Chir 70 (1999), 1–19.
4. Ireland, R., Transplantation: effect of pancreas-after-kidney transplant on renal graft survival. Nat Rev Nephrol 26 (2011), 486–492.
5. Ciancio, G., Lo Monte, A., Julian, J.F., et al. Vascular complications following bladder drained, simultaneous pancreas-kidney transplantation: the University of Miami experience. Transplant International 13 (2000), S187–S190.
6. Lo Monte, A.I., Airò Farulla, M., Cuccia, V., et al. Il trapianto sperimentale del blocco duodeno-pancreas nel maiale. Esperienza preliminare. Large Animal Review 1 (2000), 43–49.
7. Lo Monte, A.I., Fiasconaro, M., Di Marco, M., et al. Il suino come potenziale donatore multiorgano per i trapianti sull'uomo: Rischi e prospettive. Large Animal Review 1 (2000), 39–42.
8. Ricordi, C., Lacy, P.E., Finke, E.H., et al. Automated method for isolation of human pancreatic islets. Diabetes 37 (1988), 413–420.
9. Federlin, K.F., Jahr, H., Bretzel, R.G., Islet transplantation as treatment of type 1 diabetes: from experimental beginnings to clinical application. Exp Clin Endocrinol Diabetes 109 (2001), S373–S383.
10. Street, C.N., Lakey, J.R., Shapiro, A.M., et al. Islet graft assessment in the Edmonton protocol: implications for predicting long-term clinical outcome. Diabetes 53 (2004), 3107–3114.
11. Ryan, E.A., Lakey, J.R., Rajotte, R.V., et al. Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol. Diabetes 50 (2001), 710–719.
12. Gu, G., Brown, J.R., Melton, D.A., Direct lineage tracing reveals the ontogeny of pancreatic cell fates during mouse embryogenesis. Mech Dev 120 (2003), 35–43.
13. Noguchi, H., Stem cells for the treatment of diabetes. Endocr J 54 (2007), 7–16.
14. Noguchi, H., Kaneto, H., Weir, G.C., et al. PDX-1 protein containing its own antennapedia-like protein transduction domain can transduce pancreatic duct and islet cells. Diabetes 52 (2003), 1732–1737.
15. Noguchi, H., Matsumoto, S., Ueda, M., et al. Method for isolation of mouse pancreatic stem cells. Transplant Proc 40 (2008), 422–433.
16. Bonner-Weir, S., Taneja, M., Weir, G.C., et al. In vitro cultivation of human islets from expanded ductal tissue. Proc Natl Acad Sci U S A 97 (2000), 7999–8004.
17. Gao, R., Ustinov, J., Pulkkinen, M.A., et al. Characterization of endocrine progenitor cells and critical factors for their differentiation in human adult pancreatic cell culture. Diabetes 52 (2003), 2007–2015.
18. Gioviale, M.C., Damiano, G., Montalto, G., et al. Isolation and culture of beta-like cells from porcine Wirsung duct. Transplant Proc 41 (2009), 1363–1366.
19. Stassi, G., Todaro, M., Richiusa, P., et al. Expression of apoptosis-inducing CD95 (Fas/Apo-1) on human beta-cells sorted by flow-cytometry and cultured in vitro. Transplant Proc 27 (1995), 3271–3275.
20. Giordano, C., Stassi, G., Todaro, M., et al. Autofluorescence-activated sorting of human single beta cells and endocrine non-beta cells after enzymatic islet dissociation. Transplant Proc 26 (1994), 651–652.
21. Dor, Y., Brown, J., Martinez, O.I., et al. Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. Nature 429 (2004), 41–46.
22. Xu, X., D'Hoker, J., Stange, G., et al. Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas. Cell 132 (2008), 197–207.
23. Lumelsky, N., Blondel, O., Laeng, P., et al. Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets. Science 292 (2001), 1389–1394.
24. D'Amour, K.A., Bang, A.G., Eliazer, S., et al. Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat Biotechnol 11 (2006), 1392–1401.
25. Jiang, J., Au, M., Lu, K., et al. Generation of insulin producing islet-like clusters from human embryonic stem cells. Stem Cells 25 (2007), 1940–1953.
26. Tateishi, K., He, J., Taranova, O., et al. Generation of insulin-secreting islet-like clusters from human skin fibroblasts. J Biol Chem 283 (2008), 31601–31607.
27. Maehr, R., Chen, S., Snitow, M., et al. Generation of pluripotent stem cells from patients with type 1 diabetes. Proc Natl Acad Sci U S A 106 (2009), 15768–15773.
28. Xie, Q.P., Huang, H., Xu, B., et al. Human bone marrow mesenchymal stem cells differentiate into insulin-producing cells upon microenvironmental manipulation in vitro. Differentiation 77 (2009), 483–491.
29. Noguchi, H., Naziruddin, B., Shimoda, M., et al. Induction of insulin-producing cells from human pancreatic progenitor cells. Transplant Proc 42 (2010), 2081–2083.
30. Seaberg, R.M., Smukler, S.R., Kieffer, T.J., et al. Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineages. Nat Biotechnol 22 (2004), 1115–1124.
31. Yang, L., Li, S., Hatch, H., et al. In vitro transdifferentiation of adult hepatic stem cells into pancreatic endocrine hormone producing cells. Proc Natl Acad Sci U S A 99 (2002), 8078–8083.
32. Sun, B., Roh, K.H., Lee, S.R., et al. Induction of human umbilical cord blood derived stem cells with embryonic stem cell phenotypes into insulin producing islet-like structure. Biochem Biophys Res Commun 354 (2007), 919–923.
33. Chao, K.C., Chao, K.F., Fu, Y.S., et al. Islet-like clusters derived from mesenchymal stem cells in Wharton's jelly of the human umbilical cord for transplantation to control type 1 diabetes. PLoS One 3 (2008), e1451–e1458.
34. Chang, C.M., Kao, C.L., Chang, Y.L., et al. Placenta derived multipotent stem cells induced to differentiate into insulin-positive cells. Biochem Biophys Res Commun 357 (2007), 414–420.
35. Lee, A.S., Tang, C., Cao, F., et al. Effects of cell number on teratoma formation by human embryonic stem cells. Cell Cycle 8 (2009), 2608–2612.
36. Boyd, A.S., Wu, D.C., Higashi, Y., et al. Comparison of protocols used to generate insulin-producing cell clusters from mouse embryonic stem cells. Stem Cells, 26, 2008 1128–1113.
37. Blyszczuk, P., Asbrand, C., Rozzo, A., et al. Embryonic stem cells differentiate into insulin-producing cells without selection of nestin-expressing cells. Int J Dev Biol 48 (2004), 1095–1104.
38. Kitano, M., Kakinuma, M., Takatori, A., et al. Gene expression profiling of mouse embryonic stem cell progeny differentiated by Lumelsky's protocol. Cells Tissues Organs 183 (2006), 24–31.
39. Rajagopal, J., Anderson, W.J., Kume, S., et al. Insulin staining of ES cell progeny from insulin uptake. Science 299 (2003), 363–368.
40. Gradwohl, G., Dierich, A., LeMeur, M., et al. neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc Natl Acad Sci U S A 97 (2000), 1607–1611.
41. Zuk, P.A., Zhu, M., Ashjian, P., et al. Human adipose tissue is a source of multipotent stem cells. Mol Biol Cell 12 (2002), 4279–4295.
42. Timper, K., Seboek, D., Eberhardt, M., et al. Human adipose tissue-derived mesenchymal stem cells differentiate into insulin, somatostatin, and glucagon expressing cells. Biochem Biophys Res Commun 341 (2006), 1135–1140.
43. Lee, J., Han, D.J., Kim, S.C., et al. In vitro differentiation of human adipose tissue derived stem cells into cells with pancreatic phenotype by regenerating pancreas extract. Biochem Biophys Res Commun 375 (2008), 547–551.
44. Chandra, V., Swetha, G., Muthyala, S., et al. Islet-like cell aggregates generated from human adipose tissue derived stem cells ameliorate experimental diabetes in mice. PLoS One 6 (2011), e20615–e20627.
45. Phadnis, S.M., Joglekar, M.V., Dalvi, M.P., et al. Human bone marrow-derived mesenchymal cells differentiate and mature into endocrine pancreatic lineage in vivo. Cytotherapy 13 (2011), 279–293.
46. Kadam, S.S., Bhonde, R.R., Islet neogenesis from the constitutively nestin expressing human umbilical cord matrix derived mesenchymal stem cells. Islet 2 (2010), 112–120.
47. Lo Monte, A., Maione, C., Basile, V., et al. Pancreatic harvesting from multiorgan donors for islet transplantation. Minerva Chir 51 (1996), 759–764.
48. Gioviale, M.C., Damiano, G., Palumbo, V.D., et al. Pancreatic islets from non-heart-beating donor pig: two-layer preservation method in an in vitro porcine model. Int J Artif Organs 34 (2011), 519–525.
49. Gioviale, M.C., Damiano, G., Cacciabaudo, F., et al. A good breath of oxygen for beta-like cells obtained from porcine exocrine pancreatic tissue. Transplant Proc 43 (2011), 1173–1177.
50. Zanone, M.M., Favaro, E., Camussi, G., From endothelial to beta cells: insights into pancreatic islet microendothelium. Curr Diabetes Rev 4 (2008), 1–9.
51. Johansson, M., Mattsson, G., Andersson, A., et al. Islet endothelial cells and pancreatic beta-cell proliferation: studies in vitro and during pregnancy in adult rats. Endocrinology 147 (2006), 2315–2324.
52. Cabric, S., Sanchez, J., Johansson, U., et al. Anchoring of vascular endothelial growth factor to surface-immobilized heparin on pancreatic islets: implications for stimulating islet angiogenesis. Tissue Eng Part A 16 (2010), 961–970.
53. Asahara, T., Murohara, T., Sullivan, A., et al. Isolation of putative progenitor endothelial cells for angiogenesis. Science 275 (1997), 964–967.
54. Di Santo, S., Yang, Z., Wyler von Ballmoos, M., et al. Novel cell-free strategy for therapeutic angiogenesis: in vitro generated conditioned medium can replace progenitor cell transplantation. PLoS One 4 (2009), e5643–e5648.
55. Park, K.S., Kim, Y.S., Kim, J.H., et al. Trophic molecules derived from human mesenchymal stem cells enhance survival, function, and angiogenesis of isolated islets after transplantation. Transplantation 89 (2010), 509–517.
56. Mathews, V., Hanson, P.T., Ford, E., et al. Recruitment of bone marrow-derived endothelial cells to sites of pancreatic beta-cell injury. Diabetes 53 (2004), 91–98.
57. Sakata, N., Chan, N.K., Chrisler, J., et al. Bone marrow cell cotransplantation with islets improves their vascularization and function. Transplantation 89 (2010), 686–693.
58. Ito, T., Itakura, S., Todorov, I., et al. Mesenchymal stem cell and islet co-transplantation promotes graft revascularization and function. Transplantation 89 (2010), 1438–1445.
59. Luo, L., Badiavas, E., Luo, J.Z., et al. Allogeneic bone marrow supports human islet beta cell survival and function over six months. Biochem Biophys Res Commun 361 (2007), 859–864.
60. Hasegawa, Y., Ogihara, T., Yamada, T., et al. Bone marrow (BM) transplantation promotes beta-cell regeneration after acute injury through BM cell mobilization. Endocrinology 148 (2007), 2006–2015.
61. Li, F.X., Zhu, J.W., Tessem, J.S., et al. The development of diabetes in E2f1/E2f2 mutant mice reveals important roles for bone marrow-derived cells in preventing islet cell loss. Proc Natl Acad Sci U S A 100 (2003), 12935–12940.
62. Kordowich, S., Mansouri, A., Collombat, P., Reprogramming into pancreatic endocrine cells based on developmental cues. Mol Cell Endocrinol 315 (2010), 1–2.
63. Gu, G., Brown, J.R., Melton, D., Direct lineage tracing reveals the ontogeny of pancreatic cell fates during mouse embryogenesis. Mech Dev 120 (2003), 35–43.
64. Ber, I., Shternhall, K., Perl, S., et al. Functional, persistent, and extended liver to pancreas transdifferentiation. J Biol Chem 278 (2003), 31950–31957.
65. Taniguchi, H., Yamato, E., Tashiro, F., et al. Beta-cell neogenesis induced by adenovirus-mediated gene delivery of transcription factor Pdx1 into mouse pancreas. Gene Ther 10 (2003), 15–23.
66. Shternhall-Ron, K., Quintana, F.j., Perl, S., et al. Ectopic PDX1 expression in liver ameliorates type 1 diabetes. J Autoimmun 28 (2007), 134–142.
67. Kaneto, H., Nakatani, Y., Miyatsuka, T., et al. PDX1/VP16 fusion protein, together with NeuroD or Ngn3, markedly induces insulin gene transcription and ameliorates glucose tolerance. Diabetes 54 (2005), 1009–1022.
68. Baeyens, L., Bouwens, L., Can β-cells be derived from exocrine pancreas?. Diabetes, Obesity and Metabolism 10 (2008), 170–178.
69. Ruhnke, M., Ungefroren, H., Nussler, A., et al. Differentiation of in vitro-modified human peripheral blood monocytes into hepatocyte-like and pancreatic islet-like cells. Gastroenterology 128 (2005), 1774–1786.