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Volumn 92, Issue 5-6, 2014, Pages 265-275

Telmisartan Protects against Vascular Dysfunction with Peroxisome Proliferator-Activated Receptor-γ Activation in Hypertensive 5/6 Nephrectomized Rats

Author keywords

Angiotensin II type 1 receptor blocker; Aorta; Chronic kidney disease; Hypertension; Peroxisome proliferator activated receptor

Indexed keywords

2 CHLORO 5 NITROBENZANILIDE; ANGIOTENSIN 1 RECEPTOR; ENDOTHELIAL NITRIC OXIDE SYNTHASE; LOSARTAN; OSTEOPONTIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TELMISARTAN; ACETYLCHOLINE; CREATININE; NITROGEN; NITROPRUSSIDE SODIUM; UREA;

EID: 84892951282     PISSN: 00317012     EISSN: 14230313     Source Type: Journal    
DOI: 10.1159/000355482     Document Type: Article
Times cited : (12)

References (52)
  • 1
    • 12344250764 scopus 로고    scopus 로고
    • Chronic kidney disease: The global challenge
    • Meguid El Nahas A, Bello AK: Chronic kidney disease: The global challenge. Lancet 2005; 365: 331-340.
    • (2005) Lancet , vol.365 , pp. 331-340
    • Meguid El Nahas, A.1    Bello, A.K.2
  • 2
    • 0036176161 scopus 로고    scopus 로고
    • K/DOQI clinical practice guidelines for chronic kidney disease: Evaluation, classification, and stratification
    • National Kidney Foundation
    • National Kidney Foundation: K/DOQI clinical practice guidelines for chronic kidney disease: Evaluation, classification, and stratification. Am J Kidney Dis 2002; 39:S1-S266.
    • (2002) Am J Kidney Dis , vol.39 , pp. 1-266
  • 3
    • 0031733696 scopus 로고    scopus 로고
    • Clinical epidemiology of cardiovascular disease in chronic renal disease
    • Foley RN, Parfrey PS, Sarnak MJ: Clinical epidemiology of cardiovascular disease in chronic renal disease. Am J Kidney Dis 1998; 32:S112-S119.
    • (1998) Am J Kidney Dis , vol.32 , pp. 112-119
    • Foley, R.N.1    Parfrey, P.S.2    Sarnak, M.J.3
  • 5
    • 0029876704 scopus 로고    scopus 로고
    • Microalbuminuria screening by reagent strip predicts cardiovascular risk in hypertension
    • Agrawal B, Berger A, Wolf K, Luft FC: Microalbuminuria screening by reagent strip predicts cardiovascular risk in hypertension. J Hypertens 1996; 14: 223-228.
    • (1996) J Hypertens , vol.14 , pp. 223-228
    • Agrawal, B.1    Berger, A.2    Wolf, K.3    Luft, F.C.4
  • 8
    • 0034852962 scopus 로고    scopus 로고
    • Microalbuminuria is common, also in a nondiabetic, nonhypertensive population, and an independent indicator of cardiovascular risk factors and cardiovascular morbidity
    • Hillege HL, Janssen WM, Bak AA, Diercks GF, Grobbee DE, Crijns HJ, Van Gilst WH, De Zeeuw D, De Jong PE: Microalbuminuria is common, also in a nondiabetic, nonhypertensive population, and an independent indicator of cardiovascular risk factors and cardiovascular morbidity. J Intern Med 2001; 249: 519-526.
    • (2001) J Intern Med , vol.249 , pp. 519-526
    • Hillege, H.L.1    Janssen, W.M.2    Bak, A.A.3    Diercks, G.F.4    Grobbee, D.E.5    Crijns, H.J.6    Van Gilst, W.H.7    De Zeeuw, D.8    De Jong, P.E.9
  • 9
    • 1542378917 scopus 로고    scopus 로고
    • Overview: Increased cardiovascular risk in patients with minor renal dysfunction: An emerging issue with farreaching consequences
    • Ritz E, McClellan WM: Overview: Increased cardiovascular risk in patients with minor renal dysfunction: An emerging issue with farreaching consequences. J Am Soc Nephrol 2004; 15: 513-516.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 513-516
    • Ritz, E.1    McClellan, W.M.2
  • 11
    • 33744958852 scopus 로고    scopus 로고
    • Assessing kidney function - Measured and estimated glomerular filtration rate
    • Stevens LA, Coresh J, Greene T, Levey AS: Assessing kidney function - measured and estimated glomerular filtration rate. N Engl J Med 2006; 354: 2473-2483.
    • (2006) N Engl J Med , vol.354 , pp. 2473-2483
    • Stevens, L.A.1    Coresh, J.2    Greene, T.3    Levey, A.S.4
  • 12
    • 54049125389 scopus 로고    scopus 로고
    • Prevention of CVD in patients with CKD
    • in Japanese
    • Nishimoto-Hazuku A, Node K: Prevention of CVD in patients with CKD (in Japanese). Nihon Rinsho 2008; 66: 1741-1745.
    • (2008) Nihon Rinsho , vol.66 , pp. 1741-1745
    • Nishimoto-Hazuku, A.1    Node, K.2
  • 14
    • 19244365650 scopus 로고    scopus 로고
    • Thiazolidinediones
    • Yki-Jarvinen H: Thiazolidinediones. N Engl J Med 2004; 351: 1106-1118.
    • (2004) N Engl J Med , vol.351 , pp. 1106-1118
    • Yki-Jarvinen, H.1
  • 15
    • 38749117951 scopus 로고    scopus 로고
    • Inhibition of vascular angiotensin-converting enzyme by telmisartan via the peroxisome proliferatoractivated receptor- agonistic property in rats
    • Takai S, Jin D, Kimura M, Kirimura K, Sakonjo H, Tanaka K, Miyazaki M: Inhibition of vascular angiotensin-converting enzyme by telmisartan via the peroxisome proliferatoractivated receptor- agonistic property in rats. Hypertens Res 2007; 30: 1231-1237.
    • (2007) Hypertens Res , vol.30 , pp. 1231-1237
    • Takai, S.1    Jin, D.2    Kimura, M.3    Kirimura, K.4    Sakonjo, H.5    Tanaka, K.6    Miyazaki, M.7
  • 16
    • 84861341475 scopus 로고    scopus 로고
    • Telmisartan inhibits vascular dysfunction and inflammation via activation of peroxisome proliferator-activated receptor- in subtotal nephrectomized rat
    • Toba H, Tojo C, Wang J, Noda K, Kobara M, Nakata T: Telmisartan inhibits vascular dysfunction and inflammation via activation of peroxisome proliferator-activated receptor- in subtotal nephrectomized rat. Eur J Pharmacol 2012; 685: 91-98.
    • (2012) Eur J Pharmacol , vol.685 , pp. 91-98
    • Toba, H.1    Tojo, C.2    Wang, J.3    Noda, K.4    Kobara, M.5    Nakata, T.6
  • 19
    • 77951033351 scopus 로고    scopus 로고
    • Vascular calcification in animal models of CKD: A review
    • Shobeiri N, Adams MA, Holden RM: Vascular calcification in animal models of CKD: A review. Am J Nephrol 2010; 31: 471-481.
    • (2010) Am J Nephrol , vol.31 , pp. 471-481
    • Shobeiri, N.1    Adams, M.A.2    Holden, R.M.3
  • 20
    • 74049139130 scopus 로고    scopus 로고
    • Sympathetic nerves and the progression of chronic kidney disease during 5/6 nephrectomy: Studies in sympathectomized rats
    • Augustyniak RA, Picken MM, Leonard D, Zhou XJ, Zhang W, Victor RG: Sympathetic nerves and the progression of chronic kidney disease during 5/6 nephrectomy: Studies in sympathectomized rats. Clin Exp Pharmacol Physiol 2010; 37: 12-18.
    • (2010) Clin Exp Pharmacol Physiol , vol.37 , pp. 12-18
    • Augustyniak, R.A.1    Picken, M.M.2    Leonard, D.3    Zhou, X.J.4    Zhang, W.5    Victor, R.G.6
  • 22
    • 77954954191 scopus 로고    scopus 로고
    • Low dose of telmisartan prevents ischemic brain damage with peroxisome proliferator-activated receptor- activation in diabetic mice
    • Iwanami J, Mogi M, Tsukuda K, Min LJ, Sakata A, Jing F, Iwai M, Horiuchi M: Low dose of telmisartan prevents ischemic brain damage with peroxisome proliferator-activated receptor- activation in diabetic mice. J Hypertens 2010; 28: 1730-1737.
    • (2010) J Hypertens , vol.28 , pp. 1730-1737
    • Iwanami, J.1    Mogi, M.2    Tsukuda, K.3    Min, L.J.4    Sakata, A.5    Jing, F.6    Iwai, M.7    Horiuchi, M.8
  • 23
    • 79957610506 scopus 로고    scopus 로고
    • Telmisartan, a unique ARB, improves left ventricular remodeling of infarcted heart by activating PPAR
    • Maejima Y, Okada H, Haraguchi G, Onai Y, Kosuge H, Suzuki J, Isobe M: Telmisartan, a unique ARB, improves left ventricular remodeling of infarcted heart by activating PPAR-. Lab Invest 2011; 91: 932-944.
    • (2011) Lab Invest , vol.91 , pp. 932-944
    • Maejima, Y.1    Okada, H.2    Haraguchi, G.3    Onai, Y.4    Kosuge, H.5    Suzuki, J.6    Isobe, M.7
  • 24
    • 79960058644 scopus 로고    scopus 로고
    • Telmisartan protects against diabetic vascular complications in a mouse model of obesity and type diabetes, partially through peroxisome proliferator activated receptor-dependent activity
    • Toyama K, Nakamura T, Kataoka K, Yasuda O, Fukuda M, Tokutomi Y, Dong YF, Ogawa H, Kim-Mitsuyama S: Telmisartan protects against diabetic vascular complications in a mouse model of obesity and type diabetes, partially through peroxisome proliferator activated receptor-dependent activity. Biochem Biophys Res Commun 2011; 410: 508- 513.
    • (2011) Biochem Biophys Res Commun , vol.410 , pp. 508-513
    • Toyama, K.1    Nakamura, T.2    Kataoka, K.3    Yasuda, O.4    Fukuda, M.5    Tokutomi, Y.6    Dong, Y.F.7    Ogawa, H.8    Kim-Mitsuyama, S.9
  • 26
    • 79959372114 scopus 로고    scopus 로고
    • Telmisartan provides better renal protection than valsartan in a rat model of metabolic syndrome
    • Khan AH, Imig JD: Telmisartan provides better renal protection than valsartan in a rat model of metabolic syndrome. Am J Hypertens 2011; 24: 816-821.
    • (2011) Am J Hypertens , vol.24 , pp. 816-821
    • Khan, A.H.1    Imig, J.D.2
  • 28
    • 0034636121 scopus 로고    scopus 로고
    • Correction of arterial structure and endothelial dysfunction in human essential hypertension by the angiotensin receptor antagonist losartan
    • Schiffrin EL, Park JB, Intengan HD, Touyz RM: Correction of arterial structure and endothelial dysfunction in human essential hypertension by the angiotensin receptor antagonist losartan. Circulation 2000; 101: 1653- 1659.
    • (2000) Circulation , vol.101 , pp. 1653-1659
    • Schiffrin, E.L.1    Park, J.B.2    Intengan, H.D.3    Touyz, R.M.4
  • 29
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology, and pharmacology
    • Moncada S, Palmer RM, Higgs EA: Nitric oxide: Physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991; 43: 109- 142.
    • (1991) Pharmacol Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.2    Higgs, E.A.3
  • 30
    • 24144448954 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor- ligands stimulate endothelial nitric oxide production through distinct peroxisome proliferator-activated receptor- dependent mechanisms
    • Polikandriotis JA, Mazzella LJ, Rupnow HL, Hart CM: Peroxisome proliferator-activated receptor- ligands stimulate endothelial nitric oxide production through distinct peroxisome proliferator-activated receptor- dependent mechanisms. Arterioscler Thromb Vasc Biol 2005; 25: 1810-1816.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1810-1816
    • Polikandriotis, J.A.1    Mazzella, L.J.2    Rupnow, H.L.3    Hart, C.M.4
  • 31
    • 33845565499 scopus 로고    scopus 로고
    • Cardioprotection mediated by rosiglitazone, a peroxisome proliferator-activated receptor- ligand, in relation to nitric oxide
    • Gonon AT, Bulhak A, Labruto F, Sjoquist PO, Pernow J: Cardioprotection mediated by rosiglitazone, a peroxisome proliferator-activated receptor- ligand, in relation to nitric oxide. Basic Res Cardiol 2007; 102: 80-89.
    • (2007) Basic Res Cardiol , vol.102 , pp. 80-89
    • Gonon, A.T.1    Bulhak, A.2    Labruto, F.3    Sjoquist, P.O.4    Pernow, J.5
  • 34
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis - An inflammatory disease
    • Ross R: Atherosclerosis - an inflammatory disease. N Engl J Med 1999; 340: 115-126.
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 38
  • 39
    • 71749090662 scopus 로고    scopus 로고
    • Inhibition of renin-angiotensin system attenuates periadventitial inflammation and reduces atherosclerotic lesion formation
    • Fukuda D, Enomoto S, Nagai R, Sata M: Inhibition of renin-angiotensin system attenuates periadventitial inflammation and reduces atherosclerotic lesion formation. Biomed Pharmacother 2009; 63: 754-761.
    • (2009) Biomed Pharmacother , vol.63 , pp. 754-761
    • Fukuda, D.1    Enomoto, S.2    Nagai, R.3    Sata, M.4
  • 40
    • 84863109871 scopus 로고    scopus 로고
    • Outside fibroblasts play a key role in the development of inner neointima after the implantation of polytetrafluoroethylene grafts
    • Jin D, Takai S, Li Z, Sakonjo H, Otsuki Y, Shibayama Y, Miyazaki M: Outside fibroblasts play a key role in the development of inner neointima after the implantation of polytetrafluoroethylene grafts. J Pharmacol Sci 2012; 119: 139-149.
    • (2012) J Pharmacol Sci , vol.119 , pp. 139-149
    • Jin, D.1    Takai, S.2    Li, Z.3    Sakonjo, H.4    Otsuki, Y.5    Shibayama, Y.6    Miyazaki, M.7
  • 41
    • 0027136162 scopus 로고
    • Osteopontin mRNA is expressed by smooth muscle-derived foam cells in human atherosclerotic lesions of the aorta
    • Ikeda T, Shirasawa T, Esaki Y, Yoshiki S, Hirokawa K: Osteopontin mRNA is expressed by smooth muscle-derived foam cells in human atherosclerotic lesions of the aorta. J Clin Invest 1993; 92: 2814-2820.
    • (1993) J Clin Invest , vol.92 , pp. 2814-2820
    • Ikeda, T.1    Shirasawa, T.2    Esaki, Y.3    Yoshiki, S.4    Hirokawa, K.5
  • 42
    • 0028118893 scopus 로고
    • Osteopontin promotes vascular cell adhesion and spreading and is chemotactic for smooth muscle cells in vitro
    • Liaw L, Almeida M, Hart CE, Schwartz SM, Giachelli CM: Osteopontin promotes vascular cell adhesion and spreading and is chemotactic for smooth muscle cells in vitro. Circ Res 1994; 74: 214-224.
    • (1994) Circ Res , vol.74 , pp. 214-224
    • Liaw, L.1    Almeida, M.2    Hart, C.E.3    Schwartz, S.M.4    Giachelli, C.M.5
  • 43
    • 80052638308 scopus 로고    scopus 로고
    • Telmisartan prevents VCAM-1 induction and monocytic cell adhesion to endothelium exposed to non-uniform shear stress and TNF
    • Cicha I, Urschel K, Daniel WG, Garlichs CD: Telmisartan prevents VCAM-1 induction and monocytic cell adhesion to endothelium exposed to non-uniform shear stress and TNF-. Clin Hemorheol Microcirc 2011; 48: 65-73.
    • (2011) Clin Hemorheol Microcirc , vol.48 , pp. 65-73
    • Cicha, I.1    Urschel, K.2    Daniel, W.G.3    Garlichs, C.D.4
  • 44
    • 10044223533 scopus 로고    scopus 로고
    • PPAR- and LXR-dependent pathways controlling lipid metabolism and the development of atherosclerosis
    • Li AC, Glass CK: PPAR- and LXR-dependent pathways controlling lipid metabolism and the development of atherosclerosis. J Lipid Res 2004; 45: 2161-2173.
    • (2004) J Lipid Res , vol.45 , pp. 2161-2173
    • Li, A.C.1    Glass, C.K.2
  • 46
    • 73549106828 scopus 로고    scopus 로고
    • Inhibition of tumor necrosis factor-induced interleukin-6 expression by telmisartan through cross-talk of peroxisome proliferator-activated receptor- with nuclear factor-B and CCAAT/enhancer-binding protein
    • Tian Q, Miyazaki R, Ichiki T, Imayama I, Inanaga K, Ohtsubo H, Yano K, Takeda K, Sunagawa K: Inhibition of tumor necrosis factor-induced interleukin-6 expression by telmisartan through cross-talk of peroxisome proliferator- activated receptor- with nuclear factor-B and CCAAT/enhancer-binding protein-. Hypertension 2009; 53: 798-804.
    • (2009) Hypertension , vol.53 , pp. 798-804
    • Tian, Q.1    Miyazaki, R.2    Ichiki, T.3    Imayama, I.4    Inanaga, K.5    Ohtsubo, H.6    Yano, K.7    Takeda, K.8    Sunagawa, K.9
  • 47
    • 0037154548 scopus 로고    scopus 로고
    • PPAR- ligand inhibits osteopontin gene expression through interference with binding of nuclear factors to A/T-rich sequence in THP-1 cells
    • Oyama Y, Akuzawa N, Nagai R, Kurabayashi M: PPAR- ligand inhibits osteopontin gene expression through interference with binding of nuclear factors to A/T-rich sequence in THP-1 cells. Circ Res 2002; 90: 348-355.
    • (2002) Circ Res , vol.90 , pp. 348-355
    • Oyama, Y.1    Akuzawa, N.2    Nagai, R.3    Kurabayashi, M.4
  • 48
    • 65649116367 scopus 로고    scopus 로고
    • Transcriptional control of vascular smooth muscle cell proliferation by peroxisome proliferator-activated receptor- therapeutic implications for cardiovascular diseases
    • Gizard F, Bruemmer D: Transcriptional control of vascular smooth muscle cell proliferation by peroxisome proliferator-activated receptor-: Therapeutic implications for cardiovascular diseases. PPAR Res 2008; 2008: 429123.
    • (2008) PPAR Res , vol.2008 , pp. 429123
    • Gizard, F.1    Bruemmer, D.2
  • 49
    • 42049117141 scopus 로고    scopus 로고
    • Effects of telmisartan, a unique angiotensin receptor blocker with selective peroxisome proliferator- activated receptor-modulating activity, on nitric oxide bioavailability and atherosclerotic change
    • Ikejima H, Imanishi T, Tsujioka H, Kuroi A, Kobayashi K, Shiomi M, Muragaki Y, Mochizuki S, Goto M, Yoshida K, Akasaka T: Effects of telmisartan, a unique angiotensin receptor blocker with selective peroxisome proliferator- activated receptor-modulating activity, on nitric oxide bioavailability and atherosclerotic change. J Hypertens 2008; 26: 964-972.
    • (2008) J Hypertens , vol.26 , pp. 964-972
    • Ikejima, H.1    Imanishi, T.2    Tsujioka, H.3    Kuroi, A.4    Kobayashi, K.5    Shiomi, M.6    Muragaki, Y.7    Mochizuki, S.8    Goto, M.9    Yoshida, K.10    Akasaka, T.11
  • 50
    • 39749201501 scopus 로고    scopus 로고
    • Effect of telmisartan on nitric oxide - Asymmetrical dimethylarginine system: Role of angiotensin II type receptor- and peroxisome proliferator-activated receptor- signaling during endothelial aging
    • Scalera F, Martens-Lobenhoffer J, Bukowska A, Lendeckel U, Tager M, Bode-Boger SM: Effect of telmisartan on nitric oxide - asymmetrical dimethylarginine system: Role of angiotensin II type receptor- and peroxisome proliferator-activated receptor- signaling during endothelial aging. Hypertension 2008; 51: 696-703.
    • (2008) Hypertension , vol.51 , pp. 696-703
    • Scalera, F.1    Martens-Lobenhoffer, J.2    Bukowska, A.3    Lendeckel, U.4    Tager, M.5    Bode-Boger, S.M.6
  • 51
    • 48949118159 scopus 로고    scopus 로고
    • Telmisartan is more effective than losartan in reducing proteinuria in patients with diabetic nephropathy
    • Bakris G, Burgess E, Weir M, Davidai G, Koval S: Telmisartan is more effective than losartan in reducing proteinuria in patients with diabetic nephropathy. Kidney Int 2008; 74: 364-369.
    • (2008) Kidney Int , vol.74 , pp. 364-369
    • Bakris, G.1    Burgess, E.2    Weir, M.3    Davidai, G.4    Koval, S.5
  • 52
    • 84856303860 scopus 로고    scopus 로고
    • Telmisartan exerts renoprotective actions via peroxisome proliferator- activated receptor-/hepatocyte growth factor pathway independent of angiotensin II type receptor blockade
    • Kusunoki H, Taniyama Y, Azuma J, Iekushi K, Sanada F, Otsu R, Iwabayashi M, Okayama K, Rakugi H, Morishita R: Telmisartan exerts renoprotective actions via peroxisome proliferator- activated receptor-/hepatocyte growth factor pathway independent of angiotensin II type receptor blockade. Hypertension 2012; 59: 308-316.
    • (2012) Hypertension , vol.59 , pp. 308-316
    • Kusunoki, H.1    Taniyama, Y.2    Azuma, J.3    Iekushi, K.4    Sanada, F.5    Otsu, R.6    Iwabayashi, M.7    Okayama, K.8    Rakugi, H.9    Morishita, R.10


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