Information transfer by leaky, heterogeneous, protein kinase signaling systems

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 3, 2014, Pages

  Voliotis, Margaritis ^a   Perrett, Rebecca M ^b   McWilliams, Chris ^a   McArdle, Craig A ^b   Bowsher, Clive G ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Biomolecular networks; Cell sensing; Mapk signaling; Mutual information; Ultrasensitivity

Indexed keywords

PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; AVERAGING; ENZYME ACTIVITY; INFORMATION; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; THEORETICAL MODEL; CELL SIGNALING ASSAY; EXPERIMENTAL STUDY; NOISE; PHENOTYPE; PREDICTION; PROTEIN EXPRESSION; PROTEIN TRANSPORT; TASK PERFORMANCE;

BIOMOLECULAR NETWORKS; CELL SENSING; MAPK SIGNALING; MUTUAL INFORMATION; ULTRASENSITIVITY;

BAYES THEOREM; CELL NUCLEUS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEEDBACK, PHYSIOLOGICAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HELA CELLS; HUMANS; LIGANDS; MAP KINASE SIGNALING SYSTEM; MODELS, BIOLOGICAL; MULTIVARIATE ANALYSIS; PHENOTYPE; PHOSPHORYLATION;

EID: 84892937483     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1314446111     Document Type: Article

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