Deletion of the huntingtin proline-rich region does not significantly affect normal huntingtin function in mice

Journal of Huntington's Disease

Volumn 1, Issue 1, 2012, Pages 71-87

  Neveklovska, Michelle ^a   Clabough, Erin B D ^a   Steffan, Joan S ^b   Zeitlin, Scott O ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

huntingtin; Huntington's disease; mouse model; proline rich region

Indexed keywords

HUNTINGTIN; PROLINE; PROLINE RICH REGION; UNCLASSIFIED DRUG; HDH PROTEIN, MOUSE; NERVE PROTEIN; NUCLEAR PROTEIN;

AGE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BRAIN CORTEX; CONTROLLED STUDY; CORPUS STRIATUM; EMBRYO DEVELOPMENT; FEMALE; GAIT; GENDER; GENE DELETION; GRIP STRENGTH; HIPPOCAMPUS; HOMOZYGOSITY; KNOCKOUT MOUSE; MALE; MAZE TEST; MOTOR PERFORMANCE; MOUSE; MUTANT; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; PROGENY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; REFLEX; RIGHTING REFLEX; SPATIAL LEARNING; SPATIAL MEMORY; STEADY STATE; TASK PERFORMANCE; VISUAL ACUITY; WILD TYPE; AMINO ACID SEQUENCE; ANIMAL; ANIMAL BEHAVIOR; CHEMISTRY; DISEASE MODEL; GENETICS; HUNTINGTON CHOREA; INTRACELLULAR SPACE; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHOSPHORYLATION; PHYSIOLOGY; PROLINE RICH PROTEIN DOMAIN; TRANSGENIC MOUSE;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; HUNTINGTON DISEASE; INTRACELLULAR SPACE; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PHOSPHORYLATION; PROLINE; PROLINE-RICH PROTEIN DOMAINS; SEQUENCE DELETION;

EID: 84892929669     PISSN: 18796397     EISSN: 18796400     Source Type: Journal    
DOI: 10.3233/JHD-2012-120016     Document Type: Article

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