Dynamic CCAAT/enhancer binding protein-associated changes of DNA methylation in the angiotensinogen gene

Hypertension

Volumn 63, Issue 2, 2014, Pages 281-288

  Wang, Fen ^a   Demura, Masashi ^a   Cheng, Yuan ^a   Zhu, Aoshuang ^a   Karashima, Shigehiro ^a   Yoneda, Takashi ^a   Demura, Yoshiki ^b   Maeda, Yuji ^a   Namiki, Mikio ^a   Ono, Katsuhiko ^c   Nakamura, Yasuhiro ^c   Sasano, Hironobu ^c   Akagi, Tadayuki ^a   Yamagishi, Masakazu ^a   Saijoh, Kiyofumi ^a   Takeda, Yoshiyu ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b FUKUI PREFECTURAL HOSPITAL   (Japan)

^c TOHOKU UNIVERSITY HOSPITAL   (Japan)

Author keywords

angiotensinogen; CCAAT enhancer binding protein ; CEBPB protein; chromatin; DNA methylation; human; transcription initiation site

Indexed keywords

ALDOSTERONE; ANGIOTENSINOGEN; CCAAT ENHANCER BINDING PROTEIN; CCAAT ENHANCER BINDING PROTEIN BETA; GENOMIC DNA; INTERLEUKIN 6;

ADRENAL CORTEX CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; CELL NUCLEUS; CHROMATIN; CONTROLLED STUDY; DEMETHYLATION; DNA METHYLATION; GENE ACTIVATION; GENE ACTIVITY; GENE EXPRESSION; GENE SEQUENCE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HYPERTENSION; INTRAABDOMINAL FAT; MOLECULAR CLONING; NONHUMAN; PHENOTYPE; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; RAT; REPORTER GENE; SALT INTAKE; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION SITE; UPREGULATION;

EID: 84892917607     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.113.02303     Document Type: Article

References (37)

1. Yvan-Charvet L, Quignard-Boulangé A. Role of adipose tissue reninangiotensin system in metabolic and inflammatory diseases associated with obesity. Kidney Int. 2011;79:162-168.
2. Zhou TB, Yin SS, Qin YH. Association of angiotensinogen M235T gene polymorphism with end-stage renal disease risk: a meta-analysis. Mol Biol Rep. 2013;40:765-772.
3. Wang WZ. Association between T174M polymorphism in the angiotensinogen gene and risk of coronary artery disease: a meta-analysis. J Geriatr Cardiol. 2013;10:59-65.
4. Nibu Y, Takahashi S, Tanimoto K, Murakami K, Fukamizu A. Identification of cell type-dependent enhancer core element located in the 3'-downstream region of the human angiotensinogen gene. J Biol Chem. 1994;269:28598-28605.
5. Klett C, Hellmann W, Müller F, Suzuki F, Nakanishi S, Ohkubo H, Ganten D, Hackenthal E. Angiotensin II controls angiotensinogen secretion at a pretranslational level. J Hypertens Suppl. 1988;6:S442-S445.
6. Jain S, Li Y, Patil S, Kumar A. A single-nucleotide polymorphism in human angiotensinogen gene is associated with essential hypertension and affects glucocorticoid induced promoter activity. J Mol Med (Berl). 2005;83:121-131.
7. Dickson ME, Tian X, Liu X, Davis DR, Sigmund CD. Upstream stimulatory factor is required for human angiotensinogen expression and differential regulation by the A-20C polymorphism. Circ Res. 2008;103:940-947.
8. Fukamizu A, Takahashi S, Seo MS, Tada M, Tanimoto K, Uehara S, Murakami K. Structure and expression of the human angiotensinogen gene. Identification of a unique and highly active promoter. J Biol Chem. 1990;265:7576-7582.
9. Oishi T, Date S, Shimamoto Y, Saito T, Hirota K, Sugaya T, Kon Y, Fukamizu A, Tanimoto K. A nuclear receptor, hepatocyte nuclear factor 4, differently contributes to the human and mouse angiotensinogen promoter activities. J Recept Signal Transduct Res. 2010;30:484-492.
10. Jain S, Tang X, Narayanan CS, Agarwal Y, Peterson SM, Brown CD, Ott J, Kumar A. Angiotensinogen gene polymorphism at-217 affects basal promoter activity and is associated with hypertension in African-Americans. J Biol Chem. 2002;277:36889-36896.
11. Grøntved L, John S, Baek S, Liu Y, Buckley JR, Vinson C, Aguilera G, Hager GL. C/EBP maintains chromatin accessibility in liver and facilitates glucocorticoid receptor recruitment to steroid response elements. EMBO J. 2013;32:1568-1583.
12. Massiéra F, Bloch-Faure M, Ceiler D, Murakami K, Fukamizu A, Gasc JM, Quignard-Boulange A, Negrel R, Ailhaud G, Seydoux J, Meneton P, Teboul M. Adipose angiotensinogen is involved in adipose tissue growth and blood pressure regulation. FASEB J. 2001;15:2727-2729.
13. Yiannikouris F, Karounos M, Charnigo R, English VL, Rateri DL, Daugherty A, Cassis LA. Adipocyte-specific deficiency of angiotensinogen decreases plasma angiotensinogen concentration and systolic blood pressure in mice. Am J Physiol Regul Integr Comp Physiol. 2012;302:R244-R251.
14. Yiannikouris F, Gupte M, Putnam K, Thatcher S, Charnigo R, Rateri DL, Daugherty A, Cassis LA. Adipocyte deficiency of angiotensinogen prevents obesity-induced hypertension in male mice. Hypertension. 2012;60:1524-1530.
15. Aubert J, Darimont C, Safonova I, Ailhaud G, Negrel R. Regulation by glucocorticoids of angiotensinogen gene expression and secretion in adipose cells. Biochem J. 1997;328 (pt 2):701-706.
16. Masuzaki H, Yamamoto H, Kenyon CJ, Elmquist JK, Morton NM, Paterson JM, Shinyama H, Sharp MG, Fleming S, Mullins JJ, Seckl JR, Flier JS. Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in mice. J Clin Invest. 2003;112:83-90.
17. Umemura S, Nyui N, Tamura K, Hibi K, Yamaguchi S, Nakamaru M, Ishigami T, Yabana M, Kihara M, Inoue S, Ishii M. Plasma angiotensinogen concentrations in obese patients. Am J Hypertens. 1997;10:629-633.
18. Yasue S, Masuzaki H, Okada S, et al. Adipose tissue-specific regulation of angiotensinogen in obese humans and mice: impact of nutritional status and adipocyte hypertrophy. Am J Hypertens. 2010;23:425-431.
19. Van Harmelen V, Ariapart P, Hoffstedt J, Lundkvist I, Bringman S, Arner P. Increased adipose angiotensinogen gene expression in human obesity. Obes Res. 2000;8:337-341.
20. Baudrand R, Campino C, Carvajal CA, Olivieri O, Guidi G, Faccini G, Vohringer PA, Cerda J, Owen G, Kalergis AM, Fardella CE. High sodium intake is associated with increased glucocorticoid production, insulin resistance and metabolic syndrome. Clin Endocrinol (Oxf). 2013 Apr 17. doi: 10.1111/cen.12225 [Epub ahead of print]. Accessed May 15, 2013.
21. Larsen SC, Ängquist L, Sørensen TI, Heitmann BL. 24h urinary sodium excretion and subsequent change in weight, waist circumference and body composition. PLoS One. 2013;8:e69689.
22. Demura M, Takeda Y, Yoneda T, Furukawa K, Tachi A, Mabuchi H. Completely skewed X-inactivation in a mentally retarded young female with pseudohypoparathyroidism type IB and juvenile renin-dependent hypertension. J Clin Endocrinol Metab. 2003;88:3043-3049.
23. Demura M, Bulun SE. CpG dinucleotide methylation of the CYP19 I.3/II promoter modulates cAMP-stimulated aromatase activity. Mol Cell Endocrinol. 2008;283:127-132.
24. Demura M, Yoneda T, Wang F, Zen Y, Karashima S, Zhu A, Cheng Y, Yamagishi M, Takeda Y. Ectopic production of parathyroid hormone in a patient with sporadic medullary thyroid cancer. Endocr J. 2010;57:161-170.
25. Ray S, Boldogh I, Brasier AR. STAT3 NH2-terminal acetylation is activated by the hepatic acute-phase response and required for IL-6 induction of angiotensinogen. Gastroenterology. 2005;129:1616-1632.
26. Satou R, Gonzalez-Villalobos RA, Miyata K, Ohashi N, Urushihara M, Acres OW, Navar LG, Kobori H. IL-6 augments angiotensinogen in primary cultured renal proximal tubular cells. Mol Cell Endocrinol. 2009;311:24-31.
27. Siersbæk R, Nielsen R, John S, Sung MH, Baek S, Loft A, Hager GL, Mandrup S. Extensive chromatin remodelling and establishment of transcription factor 'hotspots' during early adipogenesis. EMBO J. 2011;30:1459-1472.
28. Oswald J, Engemann S, Lane N, Mayer W, Olek A, Fundele R, Dean W, Reik W, Walter J. Active demethylation of the paternal genome in the mouse zygote. Curr Biol. 2000;10:475-478.
29. Pirola L, Balcerczyk A, Tothill R, Haviv I, Kaspi A, Tonna S, Kowalczyk A, Beresford-Smith B, Macintyre G, Kelong M, Hongyu Z, Zhu J, Elosta A. The study by high-throughput sequencing of epigenetic changes in primary endothelial cells demonstrated major changes in DNA methylation and acetylation of histones after exposure to hyperglycemia. Diabetes Metab. 2012;38:A22-A22.
30. Ng CW, Yildirim F, Yap YS, Dalin S, Matthews BJ, Velez PJ, Labadorf A, Housman DE, Fraenkel E. Extensive changes in DNA methylation are associated with expression of mutant huntingtin. Proc Natl Acad Sci USA. 2013;110:2354-2359.
31. Jain S, Li Y, Patil S, Kumar A. HNF-1alpha plays an important role in IL-6-induced expression of the human angiotensinogen gene. Am J Physiol Cell Physiol. 2007;293:C401-C410.
32. Oliver WJ, Cohen EL, Neel JV. Blood pressure, sodium intake, and sodium related hormones in the Yanomamo Indians, a "no-salt" culture. Circulation. 1975;52:146-151.
33. Hoppmann J, Perwitz N, Meier B, Fasshauer M, Hadaschik D, Lehnert H, Klein J. The balance between gluco-and mineralo-corticoid action critically determines inflammatory adipocyte responses. J Endocrinol. 2010;204:153-164.
34. Pandiyan K, You JS, Yang X, Dai C, Zhou XJ, Baylin SB, Jones PA, Liang G. Functional DNA demethylation is accompanied by chromatin accessibility. Nucleic Acids Res. 2013;41:3973-3985.
35. Imbalzano AN, Kwon H, Green MR, Kingston RE. Facilitated binding of TATA-binding protein to nucleosomal DNA. Nature. 1994;370:481-485.
36. Song J, Teplova M, Ishibe-Murakami S, Patel DJ. Structure-based mechanistic insights into DNMT1-mediated maintenance DNA methylation. Science. 2012;335:709-712.
37. Bhutani N, Burns DM, Blau HM. DNA demethylation dynamics. Cell. 2011;146:866-872.