Upstream stimulatory factor is required for human angiotensinogen expression and differential regulation by the A-20C polymorphism

Circulation Research

Volumn 103, Issue 9, 2008, Pages 940-947

  Dickson, Matthew E ^a   Tian, Xin ^a   Liu, Xuebo ^a   Davis, Deborah R ^a   Sigmund, Curt D ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Chromatin; Genetics; Hypertension; Transcription

Indexed keywords

ANGIOTENSINOGEN; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; UPSTREAM STIMULATORY FACTOR 1; UPSTREAM STIMULATORY FACTOR 2; SMALL INTERFERING RNA; UPSTREAM STIMULATORY FACTOR; USF1 PROTEIN, HUMAN; USF1 PROTEIN, MOUSE; USF2 PROTEIN, HUMAN; USF2 PROTEIN, MOUSE;

ADIPOSE TISSUE; ALLELE; ANIMAL TISSUE; ARTICLE; BINDING SITE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA FLANKING REGION; GENE CONTROL; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOASSAY; LIVER CELL; MOUSE; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; TRANSACTIVATION; TRANSGENICS; ANIMAL; CELL STRAIN 3T3; GEL MOBILITY SHIFT ASSAY; GENETIC POLYMORPHISM; GENETIC TRANSFECTION; GENETICS; LIVER; METABOLISM; RNA INTERFERENCE; TRANSGENIC MOUSE; TUMOR CELL LINE;

3T3-L1 CELLS; 5' FLANKING REGION; ADIPOSE TISSUE; ANGIOTENSINOGEN; ANIMALS; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; HUMANS; LIVER; MICE; MICE, TRANSGENIC; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); RNA INTERFERENCE; RNA, SMALL INTERFERING; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION, GENETIC; TRANSFECTION; UPSTREAM STIMULATORY FACTORS;

EID: 55449090345     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.108.180653     Document Type: Article

References (32)

1. Davisson RL, Ding Y, Stec DE, Catterall JF, Sigmund CD. Novel mechanism of hypertension revealed by cell-specific targeting of human angiotensinogen in transgenic mice. Physiol Genomics. 1999;1:3-9.
2. Morimoto S, Cassell MD, Sigmund CD. Glial-and neuronal-specific expression of the renin-angiotensin system in brain alters blood pressure, water intake, and salt preference. J Biol Chem. 2002;277:33235-33241.
3. Kim HS, Krege JH, Kluckman KD, Hagaman JR, Hodgin JB, Best CF, Jennette JC, Coffman TM, Maeda N, Smithies O. Genetic control of blood pressure and the angiotensinogen locus. Proc Natl Acad Sci USA. 1995;92:2735-2739.
4. Dickson ME, Sigmund CD. Genetic basis of hypertension: revisiting angiotensinogen. Hypertension. 2006;48:14-20.
5. Jeunemaitre X, Soubrier F, Kotelevtsev YV, Lifton RP, Williams CS, Charru A, Hunt SC, Hopkins PN, Williams RR, Lalouel J-M, Corvol P. Molecular basis of human hypertension: role of angiotensinogen. Cell. 1992;71:169-180.
6. Inoue I, Nakajima T, Williams CS, Quackenbush J, Puryear R, Powers M, Cheng T, Ludwig EH, Sharma AM, Hata A, Jeunemaitre X, Lalouel JM. A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro. J Clin Invest. 1997;99:1786-1797.
7. Jain S, Li Y, Patil S, Kumar A. A single-nucleotide polymorphism in human angiotensinogen gene is associated with essential hypertension and affects glucocorticoid induced promoter activity. J Mol Med. 2005; 83:121-131.
8. Zhao YY, Zhou J, Narayanan CS, Cui Y, Kumar A. Role of C/A polymorphism at -20 on the expression of human angiotensinogen gene. Hypertension. 1999;33:108-115.
9. Nakajima T, Jorde LB, Ishigami T, Umemura S, Emi M, Lalouel JM, Inoue I. Nucleotide diversity and haplotype structure of the human angiotensinogen gene in two populations. Am J Hum Genet. 2002;70: 108-123.
10. Ishigami T, Umemura S, Tamura K, Hibi K, Nyui N, Kihara M, Yabana M, Watanabe Y, Sumida Y, Nagahara T, Ochiai H, Ishii M. Essential hypertension and 5' upstream core promoter region of human angiotensinogen gene. Hypertension. 1997;30:1325-1330.
11. Dickson ME, Zimmerman MBRK, Sigmund CD. The -20 and -217 promoter variants dominate differential angiotensinogen haplotype regulation in angiotensinogen-expressing cells. Hypertension. 2007;49: 631-639.
12. Gou D, Zhang H, Baviskar PS, Liu L. Primer extension-based method for the generation of a siRNA/miRNA expression vector. Physiol Genomics. 2007;31:554-562.
13. Harper SQ, Davidson BL. Plasmid-based RNA interference: construction of small-hairpin RNA expression vectors. Methods Mol Biol. 2005;309:219-235.
14. Yang G, Merrill DC, Thompson MW, Robillard JE, Sigmund CD. Functional expression of the human angiotensinogen gene in transgenic mice. J Biol Chem. 1994;269:32497-32502.
15. Stec DE, Davisson RL, Haskell RE, Davidson BL, Sigmund CD. Efficient liver-specific deletion of a floxed human angiotensinogen transgene by adenoviral delivery of cre-recombinase in vivo. J Biol Chem. 1999;274: 21285-21290.
16. Stec DE, Keen HL, Sigmund CD. Lower blood pressure in floxed angiotensinogen mice after adenoviral delivery of cre-recombinase. Hypertension. 2002;39:629-633.
17. Nakajima T, Inoue I, Cheng T, Lalouel JM. Molecular cloning and functional analysis of a factor that binds to the proximal promoter of human angiotensinogen. J Hum Genet. 2002;47:7-13.
18. Shimamoto Y, Ishida J, Yamagata K, Saito T, Kato H, Matsuoka T, Hirota K, Daitoku H, Nangaku M, Yamagata K, Fujii H, Takeda J, Fukamizu A. Inhibitory effect of the small heterodimer partner on hepa-tocyte nuclear factor-4 mediates bile acid-induced repression of the human angiotensinogen gene. J Biol Chem. 2004;279:7770-7776.
19. Saito T, Oishi T, Yanai K, Shimamoto Y, Fukamizu A. Cloning and characterization of a novel splicing isoform of USF1. Int J Mol Med. 2003;12:161-167.
20. Viollet B, Lefrancois-Martinez AM, Henrion A, Kahn A, Raymondjean M, Martinez A. Immunochemical characterization and transacting properties of upstream stimulatory factor isoforms. J Biol Chem. 1996;271: 1405-1415.
21. Sirito M, Lin Q, Deng JM, Behringer RR, Sawadogo M. Overlapping roles and asymmetrical cross-regulation of the USF proteins in mice. Proc Natl Acad Sci U S A. 1998;95:3758-3763.
22. West AG, Huang S, Gaszner M, Litt MD, Felsenfeld G. Recruitment of histone modifications by USF proteins at a vertebrate barrier element. Mol Cell. 2004;16:453-463.
23. Huang S, Li X, Yusufzai TM, Qiu Y, Felsenfeld G. USF1 recruits histone modification complexes and is critical for maintenance of a chromatin barrier. Mol Cell Biol. 2007;27:7991-8002.
24. Landry CR, Lemos B, Rifkin SA, Dickinson WJ, Hartl DL. Genetic properties influencing the evolvability of gene expression. Science. 2007 July 6;317:118-121.
25. Griffin MJ, Wong RH, Pandya N, Sul HS. Direct interaction between USF and SREBP-1c mediates synergistic activation of the fatty-acid synthase promoter. J Biol Chem. 2007;282:5453-5467.
26. Coon H, Xin Y, Hopkins PN, Cawthon RM, Hasstedt SJ, Hunt SC. Upstream stimulatory factor 1 associated with familial combined hyper-lipidemia, LDL cholesterol, and triglycerides. Hum Genet. 2005;117: 444-451.
27. Naukkarinen J, Gentile M, Soro-Paavonen A, Saarela J, Koistinen HA, Pajukanta P, Taskinen MR, Peltonen L. USF1 and dyslipidemias: converging evidence for a functional intronic variant. Hum Mol Genet. 2005;14:2595-2605.
28. Ng MC, Miyake K, So WY, Poon EW, Lam VK, Li JK, Cox NJ, Bell GI, Chan JC. The linkage and association of the gene encoding upstream stimulatory factor 1 with type 2 diabetes and metabolic syndrome in the Chinese population. Diabetologia. 2005;48:2018-2024.
29. Zhu Y, Casado M, Vaulont S, Sharma K. Role of upstream stimulatory factors in regulation of renal transforming growth factor-beta1. Diabetes. 2005;54:1976-1984.
30. Vallet VS, Casado M, Henrion AA, Bucchini D, Raymondjean M, Kahn A, Vaulont S. Differential roles of upstream stimulatory factors 1 and 2 in the transcriptional response of liver genes to glucose. J Biol Chem. 1998;273:20175-20179.
31. Hopkins PN, Heiss G, Ellison RC, Province MA, Pankow JS, Eckfeldt JH, Hunt SC. Coronary artery disease risk in familial combined hyper-lipidemia and familial hypertriglyceridemia: a case-control comparison from the National Heart, Lung, and Blood Institute Family Heart Study. Circulation. 2003;108:519-523.
32. Marinescu VD, Kohane IS, Riva A. MAPPER: a search engine for the computational identification of putative transcription factor binding sites in multiple genomes. BMC Bioinformatics. 2005;6:79.