Role of heterotrimeric G protein and calcium in cardiomyocyte hypertrophy induced by IGF-1

Journal of Cellular Biochemistry

Volumn 115, Issue 4, 2014, Pages 712-720

  Carrasco, Loreto ^a   Cea, Paola ^a   Rocco, Paola ^a   Peña Oyarzún, Daniel ^a   Rivera Mejias, Pablo ^a   Sotomayor Flores, Cristian ^a   Quiroga, Clara ^a   Criollo, Alfredo ^a   Ibarra, Cristian ^a,b   Chiong, Mario ^a   Lavandero, Sergio ^a,c,d  

^a UNIVERSITY OF CHILE   (Chile)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIVERSITY OF CHILE   (Chile)

^d UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

CALCIUM; CARDIAC MYOCYTE; EXTRACELLULAR SIGNAL REGULATED KINASE; HETEROTRIMERIC G PROTEIN; HYPERTROPHY; INSULIN LIKE GROWTH FACTOR 1

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; AG 538; BETA ARKCT; CALCINEURIN; CALCIUM; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; GUANINE NUCLEOTIDE BINDING PROTEIN; HETEROTRIMERIC G PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MYOSIN HEAVY CHAIN BETA; PERTUSSIS TOXIN; PROTEIN INHIBITOR; PROTEIN KINASE C ALPHA; PROTEIN TYROSINE KINASE INHIBITOR; SOMATOMEDIN C; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CALCIUM SIGNALING; CARDIOMYOCYTE HYPERTROPHY; CELL SIZE; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

CALCIUM; CARDIAC MYOCYTE; EXTRACELLULAR-SIGNAL-REGULATED KINASE; HETEROTRIMERIC G PROTEIN; HYPERTROPHY; INSULIN-LIKE GROWTH FACTOR-1;

ANIMALS; CALCINEURIN; CALCIUM; CALCIUM SIGNALING; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CARDIOMEGALY; CATECHOLS; CELLS, CULTURED; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HETEROTRIMERIC GTP-BINDING PROTEINS; INSULIN-LIKE GROWTH FACTOR I; MYOCYTES, CARDIAC; PEPTIDES; PHOSPHORYLATION; PROTEIN KINASE C-ALPHA; PROTEIN SUBUNITS; RATS, SPRAGUE-DAWLEY; RECEPTOR, IGF TYPE 1; RECOMBINANT PROTEINS; TYRPHOSTINS;

EID: 84892913493     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24712     Document Type: Article

References (49)

1. Bernardo BC, Weeks KL, Pretorius L, Mcmullen JR,. 2010. Molecular distinction between physiological and pathological cardiac hypertrophy: Experimental findings and therapeutic strategies. Pharmacol Ther 128: 191-227.
2. Blakesley VA, Scrimgeour A, Esposito D, Le Roith D,. 1996. Signaling via the insulin-like growth factor-I receptor: Does it differ from insulin receptor signaling ? Cytokine Growth Factor Rev 7: 153-159.
3. Blum G, Gazit A, Levitzki A,. 2000. Substrate competitive inhibitors of IGF-1 receptor kinase. Biochemistry 39: 15705-15712.
4. Catalucci D, Latronico MV, Ellingsen O, Condorelli G,. 2008. Physiological myocardial hypertrophy: How and why ? Front Biosci 13: 312-324.
5. Crackower MA, Oudit GY, Kozieradzki I, Sarao R, Sun H, Sasaki T, Hirsch E, Suzuki A, Shioi T, Irie-Sasaki J, Sah R, Cheng HY, Rybin VO, Lembo G, Fratta L, Oliveira-Dos-Santos AJ, Benovic JL, Kahn CR, Izumo S, Steinberg SF, Wymann MP, Backx PH, Penninger JM,. 2002. Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways. Cell 110: 737-749.
6. Dalle S, Ricketts W, Imamura T, Vollenweider P, Olefsky JM,. 2001. Insulin and insulin-like growth factor I receptors utilize different G protein signaling components. J Biol Chem 276: 15688-15695.
7. Ebensperger R, Acevedo E, Melendez J, Corbalan R, Acevedo M, Sapag-Hagar M, Jalil JE, Lavandero S,. 1998. Selective increase in cardiac IGF-1 in a rat model of ventricular hypertrophy. Biochem Biophys Res Commun 243: 20-24.
8. Ellison GM, Waring CD, Vicinanza C, Torella D,. 2012. Physiological cardiac remodelling in response to endurance exercise training: Cellular and molecular mechanisms. Heart 98: 5-10.
9. Fagard RH,. 1997. Impact of different sports and training on cardiac structure and function. Cardiol Clin 15: 397-412.
10. Fernandez AM, Jimenez S, Mecha M, Davila D, Guaza C, Vitorica J, Torres-Aleman I,. 2012. Regulation of the phosphatase calcineurin by insulin-like growth factor I unveils a key role of astrocytes in Alzheimer's pathology. Mol Psychiatry 17: 705-718.
11. Finn SG, Plonk SG, Fuller SJ,. 1999. G alpha 13 stimulates gene expression and increases cell size in cultured neonatal rat ventricular myocytes. Cardiovasc Res 42: 140-148.
12. Foncea R, Varela S, Sapag-Hagar M, Lavandero S,. 1995. Changes in protein kinase C activity, subcellular distribution and protein phosphorylation during the lactogenic cycle in the rat mammary tissue. Res Commun Mol Pathol Pharmacol 87: 253-268.
13. Foncea R, Andersson M, Ketterman A, Blakesley V, Sapag-Hagar M, Sugden PH, Leroith D, Lavandero S,. 1997. Insulin-like growth factor-I rapidly activates multiple signal transduction pathways in cultured rat cardiac myocytes. J Biol Chem 272: 19115-19124.
14. 2+ release from IP3-sensitive stores and calcium/calmodulin kinase II phosphorylation of the alpha1 subunit EF hand. J Neurosci 26: 6259-6268.
15. Gooch JL, Tang Y, Ricono JM, Abboud HE,. 2001. Insulin-like growth factor-I induces renal cell hypertrophy via a calcineurin-dependent mechanism. J Biol Chem 276: 42492-42500.
16. Haddad F, Adams GR,. 2004. Inhibition of MAP/ERK kinase prevents IGF-I-induced hypertrophy in rat muscles. J Appl Physiol 96: 203-210.
17. Hallak H, Seiler AE, Green JS, Ross BN, Rubin R,. 2000. Association of heterotrimeric G(i) with the insulin-like growth factor-I receptor. Release of G(beta gamma) subunits upon receptor activation. J Biol Chem 275: 2255-2258.
18. 2+ requirement for NO production between proteinase-activated receptor 1 and 4 (PAR1 and PAR4) in vascular endothelial cells. J Pharmacol Exp Ther 322: 668-677.
19. Ibarra C, Estrada M, Carrasco L, Chiong M, Liberona JL, Cardenas C, Diaz-Araya G, Jaimovich E, Lavandero S,. 2004. Insulin-like growth factor-1 induces an inositol 1,4,5-trisphosphate-dependent increase in nuclear and cytosolic calcium in cultured rat cardiac myocytes. J Biol Chem 279: 7554-7565.
20. Ibarra C, Vicencio JM, Estrada M, Lin Y, Rocco P, Rebellato P, Munoz JP, Garcia-Prieto J, Quest AF, Chiong M, Davidson SM, Bulatovic I, Grinnemo KH, Larsson O, Szabadkai G, Uhlen P, Jaimovich E, Lavandero S,. 2013. Local control of nuclear calcium signaling in cardiac myocytes by perinuclear microdomains of sarcolemmal insulin-like growth factor 1 receptors. Circ Res 112: 236-245.
21. Ito H, Hiroe M, Hirata Y, Tsujino M, Adachi S, Shichiri M, Koike A, Nogami A, Marumo F,. 1993. Insulin-like growth factor-I induces hypertrophy with enhanced expression of muscle specific genes in cultured rat cardiomyocytes. Circulation 87: 1715-1721.
22. Kim J, Wende AR, Sena S, Theobald HA, Soto J, Sloan C, Wayment BE, Litwin SE, Holzenberger M, Leroith D, Abel ED,. 2008. Insulin-like growth factor I receptor signaling is required for exercise-induced cardiac hypertrophy. Mol Endocrinol 22: 2531-2543.
23. Koch WJ, Hawes BE, Inglese J, Luttrell LM, Lefkowitz RJ,. 1994. Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates G beta gamma-mediated signaling. J Biol Chem 269: 6193-6197.
24. Kuemmerle JF, Murthy KS,. 2001. Coupling of the insulin-like growth factor-I receptor tyrosine kinase to Gi2 in human intestinal smooth muscle: Gbetagamma-dependent mitogen-activated protein kinase activation and growth. J Biol Chem 276: 7187-7194.
25. Lavandero S, Foncea R, Perez V, Sapag-Hagar M,. 1998. Effect of inhibitors of signal transduction on IGF-1-induced protein synthesis associated with hypertrophy in cultured neonatal rat ventricular myocytes. FEBS Lett 422: 193-196.
26. Louch WE, Sheehan KA, Wolska BM,. 2011. Methods in cardiomyocyte isolation, culture, and gene transfer. J Mol Cell Cardiol 51: 288-298.
27. Lu G, Ashraf M, Haider KH,. 2012. Insulin-like growth factor-1 preconditioning accentuates intrinsic survival mechanism in stem cells to resist ischemic injury by orchestrating protein kinase calpha-erk1/2 activation. Antioxid Redox Signal 16: 217-227.
28. Luttrell LM, Van Biesen T, Hawes BE, Koch WJ, Touhara K, Lefkowitz RJ,. 1995. G beta gamma subunits mediate mitogen-activated protein kinase activation by the tyrosine kinase insulin-like growth factor 1 receptor. J Biol Chem 270: 16495-16498.
29. Maldonado C, Cea P, Adasme T, Collao A, Diaz-Araya G, Chiong M, Lavandero S,. 2005. IGF-1 protects cardiac myocytes from hyperosmotic stress-induced apoptosis via CREB. Biochem Biophys Res Commun 336: 1112-1118.
30. Maniar R, Pecherskaya A, Ila R, Solem M,. 2005. PKC alpha-dependent regulation of the IGF1 receptor in adult and embryonic rat cardiomyocytes. Mol Cell Biochem 275: 15-24.
31. Mcmullen JR, Izumo S,. 2006. Role of the insulin-like growth factor 1 (IGF1)/phosphoinositide-3-kinase (PI3K) pathway mediating physiological cardiac hypertrophy. Novartis Found Symp 274: 90-111.
32. Miyashita T, Takeishi Y, Takahashi H, Kato S, Kubota I, Tomoike H,. 2001. Role of calcineurin in insulin-like growth factor-1-induced hypertrophy of cultured adult rat ventricular myocytes. Jpn Circ J 65: 815-819.
33. Molkentin JD,. 2004. Calcineurin-NFAT signaling regulates the cardiac hypertrophic response in coordination with the MAPKs. Cardiovasc Res 63: 467-475.
34. Morales MP, Galvez A, Eltit JM, Ocaranza P, Diaz-Araya G, Lavandero S,. 2000. IGF-1 regulates apoptosis of cardiac myocyte induced by osmotic-stress. Biochem Biophys Res Commun 270: 1029-1035.
35. Munoz JP, Collao A, Chiong M, Maldonado C, Adasme T, Carrasco L, Ocaranza P, Bravo R, Gonzalez L, Diaz-Araya G, Hidalgo C, Lavandero S,. 2009. The transcription factor MEF2C mediates cardiomyocyte hypertrophy induced by IGF-1 signaling. Biochem Biophys Res Commun 388: 155-160.
36. Nishimoto I, Ogata E, Kojima I,. 1987. Pertussis toxin inhibits the action of insulin-like growth factor-I. Biochem Biophys Res Commun 148: 403-411.
37. O'sullivan JF, Leblond AL, Kelly G, Kumar AH, Metharom P, Buneker CK, Alizadeh-Vikali N, Hristova I, Hynes BG, O'Connor R, Caplice NM,. 2011. Potent long-term cardioprotective effects of single low-dose insulin-like growth factor-1 treatment postmyocardial infarction. Circ Cardiovasc Interv 4: 327-335.
38. Patel TB,. 2004. Single transmembrane spanning heterotrimeric G protein-coupled receptors and their signaling cascades. Pharmacol Rev 56: 371-385.
39. Pecherskaya A, Solem M,. 2000. IGF1 activates PKC alpha-dependent protein synthesis in adult rat cardiomyocytes. Mol Cell Biol Res Commun 4: 166-171.
40. Perrault R, Wright B, Storie B, Hatherell A, Zahradka P,. 2011. Tyrosine kinase-independent activation of extracellular-regulated kinase (ERK) 1/2 by the insulin-like growth factor-1 receptor. Cell Signal 23: 739-746.
41. Rozengurt E,. 2007. Mitogenic signaling pathways induced by G protein-coupled receptors. J Cell Physiol 213: 589-602.
42. Sarbassov DD, Jones LG, Peterson CA,. 1997. Extracellular signal-regulated kinase-1 and -2 respond differently to mitogenic and differentiative signaling pathways in myoblasts. Mol Endocrinol 11: 2038-2047.
43. Shah AS, White DC, Emani S, Kypson AP, Lilly RE, Wilson K, Glower DD, Lefkowitz RJ, Koch WJ,. 2001. In vivo ventricular gene delivery of a beta-adrenergic receptor kinase inhibitor to the failing heart reverses cardiac dysfunction. Circulation 103: 1311-1316.
44. Sugden PH,. 2001. Signalling pathways in cardiac myocyte hypertrophy. Ann Med 33: 611-622.
45. Sun HY, Zhao RR, Zhi JM,. 2000. Insulin-like growth factor I inhibits cardiomyocyte apoptosis and the underlying signal transduction pathways. Methods Find Exp Clin Pharmacol 22: 601-607.
46. Vijayan K, Szotek EL, Martin JL, Samarel AM,. 2004. Protein kinase C-alpha-induced hypertrophy of neonatal rat ventricular myocytes. Am J Physiol 287: H2777-H2789.
47. Weber KT, Brilla CG,. 1993. Structural basis for pathologic left ventricular hypertrophy. Clin Cardiol 16: II10-II14.
48. Wilkins BJ, Molkentin JD,. 2004. Calcium-calcineurin signaling in the regulation of cardiac hypertrophy. Biochem Biophys Res Commun 322: 1178-1191.
49. Zheng Z, Wang ZM, Delbono O,. 2004. Ca(2+) calmodulin kinase and calcineurin mediate IGF-1-induced skeletal muscle dihydropyridine receptor alpha(1S) transcription. J Membr Biol 197: 101-112.