Role of calcineurin in insulin-like growth factor-1-induced hypertrophy of cultured adult rat ventricular myocytes

Japanese Circulation Journal

Volumn 65, Issue 9, 2001, Pages 815-819

  Miyashita, T ^a   Takeishi, Y ^a   Takahashi, H ^a   Kato, S ^a   Kubota, I ^a   Tomoike, H ^a  

^a YAMAGATA UNIVERSITY   (Japan)

Author keywords

Calcineurin; Cardiomyocyte; Hypertrophy; IGF 1; Signal transduction

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ANGIOTENSIN; ATRIAL NATRIURETIC FACTOR; CALCINEURIN; CHELERYTHRINE; CYCLOSPORIN A; ENDOTHELIN 1; GENISTEIN; INTERLEUKIN 6; PHENYLEPHRINE; PROTEIN TYROSINE KINASE INHIBITOR; SOMATOMEDIN C;

ANIMAL CELL; ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; CORRELATION FUNCTION; ENZYME ACTIVITY; HEART CELL CULTURE; HEART HYPERTROPHY; HEART VENTRICLE; HUMORAL IMMUNITY; MALE; NONHUMAN; PATHOPHYSIOLOGY; RAT; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS;

ANIMALS; ATRIAL NATRIURETIC FACTOR; CALCINEURIN; CARDIOMEGALY; CELL SIZE; CELLS, CULTURED; ENZYME INHIBITORS; HEART VENTRICLES; INSULIN-LIKE GROWTH FACTOR I; MALE; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 0034841852     PISSN: 00471828     EISSN: None     Source Type: Journal    
DOI: 10.1253/jcj.65.815     Document Type: Article

References (36)

1. Epidemiology of congestive heart failure: The Framingham Study
2. The cellular pathophysiology of progression to heart failure
3. Cardiac hypertrophy: Mechanical, neuronal, and endocrine dependence
4. Control of cardiac gene expression by mechanical stress
5. Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice
6. Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy
7. Activation of JAK-STAT and MAP kinases by leukemia inhibitory factor through gp130 in cardiac myocytes
8. Insulin like growth factor-1 induces hypertrophy with enhanced expression of muscle specific genes in cultured rat cardiomyocytes
9. Endothelin-1 and fibroblast growth factors stimulate the mitogen-activated protein kinase signaling cascade in cardiac myocytes: The potential role of the cascade in the integration of two signaling pathways leading to myocyte hypertrophy
10. Induction of the skeletal α-actin gene in α1-adrenoceptor-mediated hypertrophy of rat cardiac myocytes
11. Endothelin-1 induces hypertrophy with enhanced expression of muscle specific genes in cultured neonatal rat cardiomyocyte
12. Angiotensin II-induced growth responses in isolated adult rat hearts: Evidence for load-independent induction of cardiac protein synthesis by angiotensin II
13. Effect of inhibitors of signal transduction on IGF-1-induced protein synthesis associated with hypertrophy in cultured neonatal rat ventricular myocytes
14. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy
15. Failure of calcineurin inhibitors to prevent pressure-overload left ventricular hypertrophy in rats
16. Pressure overload induces severe hypertrophy in mice treated with cyclosporine, an inhibitor of calcineurin
17. Calcineurin plays a critical role, in pressure overload-induced cardiac hypertrophy
18. Calcineurin inhibitor attenuates left ventricular hypertrophy, leading to prevention of heart failure in hypertensive rats
19. Calmodulin kinases II and IV and calcineurin are involved in leukemia inhibitory factor-induced cardiac hypertrophy in rats
20. 2+ channels by IGF-1
21. Adult rat ventricular myocytes cultured in defined medium: Phenotype and electromechanical function
22. Cross-talk between receptor-mediated phospholipase C-beta and D via protein kinase C as intracellular signal possibly leading to hypertrophy in serum-free cultured cardiomyocytes
23. Angiotensin II interferes with interleukin 6-induced Stat3 signaling by a pathway involving mitogen-activated protein kinase kinase I
24. + channel expression differentially in cultured newborn rat ventricular cells
25. Mechanical loading activates mitogen-activated protein kinase and S6 peptide kinase in cultured rat cardiac myocytes
26. p38 mitogen-activated protein kinase pathway portents adult rat ventricular myocytes against α-adrenergic receptor-stimulated apotosis
27. Protective effects of low and high doses of cyclosporin A against reoxygenation injury in isolated rat cardiomyocytes are associated with differential effects on mitochondrial calcium levels
28. Mechanism of β-adrenergic receptor upregulation induced by ACE inhibition in cultured neonatal rat cardiac myocytes: Roles of bradykinin and protein kinase C
29. Use of fluorinated tyrosine phosphates to probe the substrate specificity of the low molecular weight phosphatase activity of calcineurin
30. Characterization and kinetic analysis of the intracellular domain of human protein tyrosine phosphatase β (HPTP β) using synthetic phosphopeptides
31. Transgenic overexpression of constitutively active protein kinase C causes concentric cardiac hypertrophy
32. 2+-signaling proteins induced by chronic volume overload in rabbits
33. Protein kinase C isoform expression and regulation in the developing rat heart
34. Insulin-like growth factor I as a cardiac hormone: Physiological and pathophysiological implications in heart disease
35. Prevention of cardiac hypertrophy in mice by calcineurin inhibition
36. IGF-1 induced skeletal muscle hypertrophy through calcineurin in association with GATA-2 and NF-ATc 1