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Volumn 67, Issue , 2014, Pages 86-93

P38α regulates SERCA2a function

Author keywords

Cardiac contractility; P38; Phospholamban; SERCA2a

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); CYCLIC AMP DEPENDENT PROTEIN KINASE; G PROTEIN COUPLED RECEPTOR KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE 14; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2A; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE 2; SMALL INTERFERING RNA; THREONINE; UNCLASSIFIED DRUG;

EID: 84892888945     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2013.12.005     Document Type: Article
Times cited : (22)

References (34)
  • 2
    • 43549098268 scopus 로고    scopus 로고
    • Calcium cycling and signaling in cardiac myocytes
    • Bers D.M. Calcium cycling and signaling in cardiac myocytes. Annu Rev Physiol 2008, 70:23-49.
    • (2008) Annu Rev Physiol , vol.70 , pp. 23-49
    • Bers, D.M.1
  • 3
    • 84862286538 scopus 로고    scopus 로고
    • Modulation of cardiac contractility by the phospholamban/SERCA2a regulatome
    • Kranias E.G., Hajjar R.J. Modulation of cardiac contractility by the phospholamban/SERCA2a regulatome. Circ Res 2012, 110:1646-1660.
    • (2012) Circ Res , vol.110 , pp. 1646-1660
    • Kranias, E.G.1    Hajjar, R.J.2
  • 4
    • 79960787927 scopus 로고    scopus 로고
    • Phosphatase-1 inhibitor-1 in physiological and pathological beta-adrenoceptor signalling
    • Wittkopper K., Dobrev D., Eschenhagen T., El-Armouche A. Phosphatase-1 inhibitor-1 in physiological and pathological beta-adrenoceptor signalling. Cardiovasc Res 2011, 91:392-401.
    • (2011) Cardiovasc Res , vol.91 , pp. 392-401
    • Wittkopper, K.1    Dobrev, D.2    Eschenhagen, T.3    El-Armouche, A.4
  • 5
    • 11144307292 scopus 로고    scopus 로고
    • STRESS signaling pathways that modulate cardiac myocyte apoptosis
    • Baines C.P., Molkentin J.D. STRESS signaling pathways that modulate cardiac myocyte apoptosis. J Mol Cell Cardiol 2005, 38:47-62.
    • (2005) J Mol Cell Cardiol , vol.38 , pp. 47-62
    • Baines, C.P.1    Molkentin, J.D.2
  • 6
    • 78149478401 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale
    • Rose B.A., Force T., Wang Y. Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale. Physiol Rev 2010, 90:1507-1546.
    • (2010) Physiol Rev , vol.90 , pp. 1507-1546
    • Rose, B.A.1    Force, T.2    Wang, Y.3
  • 7
    • 33746200175 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase: a future target for heart failure therapy?
    • Kerkela R., Force T. p38 mitogen-activated protein kinase: a future target for heart failure therapy?. J Am Coll Cardiol 2006, 48:556-558.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 556-558
    • Kerkela, R.1    Force, T.2
  • 8
    • 0037040161 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase mediates a negative inotropic effect in cardiac myocytes
    • Liao P., Wang S.Q., Wang S., Zheng M., Zheng M., Zhang S.J., et al. p38 mitogen-activated protein kinase mediates a negative inotropic effect in cardiac myocytes. Circ Res 2002, 90:190-196.
    • (2002) Circ Res , vol.90 , pp. 190-196
    • Liao, P.1    Wang, S.Q.2    Wang, S.3    Zheng, M.4    Zheng, M.5    Zhang, S.J.6
  • 9
    • 0034704157 scopus 로고    scopus 로고
    • Beta 2-adrenergic receptor-induced p38 MAPK activation is mediated by protein kinase A rather than by Gi or gbeta gamma in adult mouse cardiomyocytes
    • Zheng M., Zhang S.J., Zhu W.Z., Ziman B., Kobilka B.K., Xiao R.P. Beta 2-adrenergic receptor-induced p38 MAPK activation is mediated by protein kinase A rather than by Gi or gbeta gamma in adult mouse cardiomyocytes. J Biol Chem 2000, 275:40635-40640.
    • (2000) J Biol Chem , vol.275 , pp. 40635-40640
    • Zheng, M.1    Zhang, S.J.2    Zhu, W.Z.3    Ziman, B.4    Kobilka, B.K.5    Xiao, R.P.6
  • 10
    • 33746198344 scopus 로고    scopus 로고
    • Activation of p38 mitogen-activated protein kinase contributes to the early cardiodepressant action of tumor necrosis factor
    • Bellahcene M., Jacquet S., Cao X.B., Tanno M., Haworth R.S., Layland J., et al. Activation of p38 mitogen-activated protein kinase contributes to the early cardiodepressant action of tumor necrosis factor. J Am Coll Cardiol 2006, 48:545-555.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 545-555
    • Bellahcene, M.1    Jacquet, S.2    Cao, X.B.3    Tanno, M.4    Haworth, R.S.5    Layland, J.6
  • 13
    • 33847038271 scopus 로고    scopus 로고
    • P38-MAPK induced dephosphorylation of alpha-tropomyosin is associated with depression of myocardial sarcomeric tension and ATPase activity
    • Vahebi S., Ota A., Li M., Warren C.M., de Tombe P.P., Wang Y., et al. p38-MAPK induced dephosphorylation of alpha-tropomyosin is associated with depression of myocardial sarcomeric tension and ATPase activity. Circ Res 2007, 100:408-415.
    • (2007) Circ Res , vol.100 , pp. 408-415
    • Vahebi, S.1    Ota, A.2    Li, M.3    Warren, C.M.4    de Tombe, P.P.5    Wang, Y.6
  • 14
    • 55949117098 scopus 로고    scopus 로고
    • Functionally opposing roles of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase in the regulation of cardiac contractility
    • Szokodi I., Kerkela R., Kubin A.M., Sarman B., Pikkarainen S., Konyi A., et al. Functionally opposing roles of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase in the regulation of cardiac contractility. Circulation 2008, 118:1651-1658.
    • (2008) Circulation , vol.118 , pp. 1651-1658
    • Szokodi, I.1    Kerkela, R.2    Kubin, A.M.3    Sarman, B.4    Pikkarainen, S.5    Konyi, A.6
  • 15
    • 0038095180 scopus 로고    scopus 로고
    • The MKK6-p38 MAPK pathway prolongs the cardiac contractile calcium transient, downregulates SERCA2, and activates NF-AT
    • Andrews C., Ho P.D., Dillmann W.H., Glembotski C.C., McDonough P.M. The MKK6-p38 MAPK pathway prolongs the cardiac contractile calcium transient, downregulates SERCA2, and activates NF-AT. Cardiovasc Res 2003, 59:46-56.
    • (2003) Cardiovasc Res , vol.59 , pp. 46-56
    • Andrews, C.1    Ho, P.D.2    Dillmann, W.H.3    Glembotski, C.C.4    McDonough, P.M.5
  • 16
    • 0035834071 scopus 로고    scopus 로고
    • The in vivo role of p38 MAP kinases in cardiac remodeling and restrictive cardiomyopathy
    • Liao P., Georgakopoulos D., Kovacs A., Zheng M., Lerner D., Pu H., et al. The in vivo role of p38 MAP kinases in cardiac remodeling and restrictive cardiomyopathy. Proc Natl Acad Sci U S A 2001, 98:12283-12288.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 12283-12288
    • Liao, P.1    Georgakopoulos, D.2    Kovacs, A.3    Zheng, M.4    Lerner, D.5    Pu, H.6
  • 17
    • 0027497584 scopus 로고
    • Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart
    • Ungerer M., Bohm M., Elce J.S., Erdmann E., Lohse M.J. Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart. Circulation 1993, 87:454-463.
    • (1993) Circulation , vol.87 , pp. 454-463
    • Ungerer, M.1    Bohm, M.2    Elce, J.S.3    Erdmann, E.4    Lohse, M.J.5
  • 18
    • 0033521109 scopus 로고    scopus 로고
    • Feedback inhibition of G protein-coupled receptor kinase 2 (GRK2) activity by extracellular signal-regulated kinases
    • Pitcher J.A., Tesmer J.J., Freeman J.L., Capel W.D., Stone W.C., Lefkowitz R.J. Feedback inhibition of G protein-coupled receptor kinase 2 (GRK2) activity by extracellular signal-regulated kinases. J Biol Chem 1999, 274:34531-34534.
    • (1999) J Biol Chem , vol.274 , pp. 34531-34534
    • Pitcher, J.A.1    Tesmer, J.J.2    Freeman, J.L.3    Capel, W.D.4    Stone, W.C.5    Lefkowitz, R.J.6
  • 20
    • 33745205607 scopus 로고    scopus 로고
    • Role of calcineurin and protein phosphatase-2A in the regulation of phosphatase inhibitor-1 in cardiac myocytes
    • El-Armouche A., Bednorz A., Pamminger T., Ditz D., Didie M., Dobrev D., et al. Role of calcineurin and protein phosphatase-2A in the regulation of phosphatase inhibitor-1 in cardiac myocytes. Biochem Biophys Res Commun 2006, 346:700-706.
    • (2006) Biochem Biophys Res Commun , vol.346 , pp. 700-706
    • El-Armouche, A.1    Bednorz, A.2    Pamminger, T.3    Ditz, D.4    Didie, M.5    Dobrev, D.6
  • 21
    • 13644256191 scopus 로고    scopus 로고
    • A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress
    • Boyce M., Bryant K.F., Jousse C., Long K., Harding H.P., Scheuner D., et al. A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress. Science 2005, 307:935-939.
    • (2005) Science , vol.307 , pp. 935-939
    • Boyce, M.1    Bryant, K.F.2    Jousse, C.3    Long, K.4    Harding, H.P.5    Scheuner, D.6
  • 22
    • 0032167375 scopus 로고    scopus 로고
    • Fostriecin, an inhibitor of protein phosphatase 2A, limits myocardial infarct size even when administered after onset of ischemia
    • Weinbrenner C., Baines C.P., Liu G.S., Armstrong S.C., Ganote C.E., Walsh A.H., et al. Fostriecin, an inhibitor of protein phosphatase 2A, limits myocardial infarct size even when administered after onset of ischemia. Circulation 1998, 98:899-905.
    • (1998) Circulation , vol.98 , pp. 899-905
    • Weinbrenner, C.1    Baines, C.P.2    Liu, G.S.3    Armstrong, S.C.4    Ganote, C.E.5    Walsh, A.H.6
  • 23
    • 33846963541 scopus 로고    scopus 로고
    • Acute modulation of PP2a and troponin I phosphorylation in ventricular myocytes: studies with a novel PP2a peptide inhibitor
    • Deshmukh P.A., Blunt B.C., Hofmann P.A. Acute modulation of PP2a and troponin I phosphorylation in ventricular myocytes: studies with a novel PP2a peptide inhibitor. Am J Physiol Heart Circ Physiol 2007, 292:H792-H799.
    • (2007) Am J Physiol Heart Circ Physiol , vol.292
    • Deshmukh, P.A.1    Blunt, B.C.2    Hofmann, P.A.3
  • 24
    • 41549160315 scopus 로고    scopus 로고
    • Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival
    • Junttila M.R., Li S.P., Westermarck J. Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival. FASEB J 2008, 22:954-965.
    • (2008) FASEB J , vol.22 , pp. 954-965
    • Junttila, M.R.1    Li, S.P.2    Westermarck, J.3
  • 25
    • 0037049977 scopus 로고    scopus 로고
    • Cardiac excitation-contraction coupling
    • Bers D.M. Cardiac excitation-contraction coupling. Nature 2002, 415:198-205.
    • (2002) Nature , vol.415 , pp. 198-205
    • Bers, D.M.1
  • 26
    • 84870241098 scopus 로고    scopus 로고
    • Altered sarcoplasmic reticulum calcium cycling-targets for heart failure therapy
    • Kho C., Lee A., Hajjar R.J. Altered sarcoplasmic reticulum calcium cycling-targets for heart failure therapy. Nat Rev Cardiol 2012, 9:717-733.
    • (2012) Nat Rev Cardiol , vol.9 , pp. 717-733
    • Kho, C.1    Lee, A.2    Hajjar, R.J.3
  • 27
    • 0022921924 scopus 로고
    • Sequence analysis of phospholamban. Identification of phosphorylation sites and two major structural domains
    • Simmerman H.K., Collins J.H., Theibert J.L., Wegener A.D., Jones L.R. Sequence analysis of phospholamban. Identification of phosphorylation sites and two major structural domains. J Biol Chem 1986, 261:13333-13341.
    • (1986) J Biol Chem , vol.261 , pp. 13333-13341
    • Simmerman, H.K.1    Collins, J.H.2    Theibert, J.L.3    Wegener, A.D.4    Jones, L.R.5
  • 28
    • 67650710788 scopus 로고    scopus 로고
    • Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology
    • Nicolaou P., Hajjar R.J., Kranias E.G. Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology. J Mol Cell Cardiol 2009, 47:365-371.
    • (2009) J Mol Cell Cardiol , vol.47 , pp. 365-371
    • Nicolaou, P.1    Hajjar, R.J.2    Kranias, E.G.3
  • 30
    • 20244377242 scopus 로고    scopus 로고
    • Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase 1
    • Pathak A., del Monte F., Zhao W., Schultz J.E., Lorenz J.N., Bodi I., et al. Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase 1. Circ Res 2005, 96:756-766.
    • (2005) Circ Res , vol.96 , pp. 756-766
    • Pathak, A.1    del Monte, F.2    Zhao, W.3    Schultz, J.E.4    Lorenz, J.N.5    Bodi, I.6
  • 31
    • 1642388834 scopus 로고    scopus 로고
    • PKC-alpha regulates cardiac contractility and propensity toward heart failure
    • Braz J.C., Gregory K., Pathak A., Zhao W., Sahin B., Klevitsky R., et al. PKC-alpha regulates cardiac contractility and propensity toward heart failure. Nat Med 2004, 10:248-254.
    • (2004) Nat Med , vol.10 , pp. 248-254
    • Braz, J.C.1    Gregory, K.2    Pathak, A.3    Zhao, W.4    Sahin, B.5    Klevitsky, R.6
  • 32
    • 76649092318 scopus 로고    scopus 로고
    • Constitutively active phosphatase inhibitor-1 improves cardiac contractility in young mice but is deleterious after catecholaminergic stress and with aging
    • Wittkopper K., Fabritz L., Neef S., Ort K.R., Grefe C., Unsold B., et al. Constitutively active phosphatase inhibitor-1 improves cardiac contractility in young mice but is deleterious after catecholaminergic stress and with aging. J Clin Invest 2010, 120:617-626.
    • (2010) J Clin Invest , vol.120 , pp. 617-626
    • Wittkopper, K.1    Fabritz, L.2    Neef, S.3    Ort, K.R.4    Grefe, C.5    Unsold, B.6
  • 33
    • 2442647676 scopus 로고    scopus 로고
    • Essential role of troponin I in the positive inotropic response to isoprenaline in mouse hearts contracting auxotonically
    • Layland J., Grieve D.J., Cave A.C., Sparks E., Solaro R.J., Shah A.M. Essential role of troponin I in the positive inotropic response to isoprenaline in mouse hearts contracting auxotonically. J Physiol 2004, 556:835-847.
    • (2004) J Physiol , vol.556 , pp. 835-847
    • Layland, J.1    Grieve, D.J.2    Cave, A.C.3    Sparks, E.4    Solaro, R.J.5    Shah, A.M.6
  • 34
    • 0024246121 scopus 로고
    • Kinetic and equilibrium characterization of an energy-transducing enzyme and its partial reactions
    • Inesi G., Kurzmack M., Lewis D. Kinetic and equilibrium characterization of an energy-transducing enzyme and its partial reactions. Methods Enzymol 1988, 157:154-190.
    • (1988) Methods Enzymol , vol.157 , pp. 154-190
    • Inesi, G.1    Kurzmack, M.2    Lewis, D.3


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