-
1
-
-
84876325151
-
Calcium flux balance in the heart
-
Eisner D., Bode E., Venetucci L., Trafford A. Calcium flux balance in the heart. J Mol Cell Cardiol 2013, 58:110-117.
-
(2013)
J Mol Cell Cardiol
, vol.58
, pp. 110-117
-
-
Eisner, D.1
Bode, E.2
Venetucci, L.3
Trafford, A.4
-
2
-
-
43549098268
-
Calcium cycling and signaling in cardiac myocytes
-
Bers D.M. Calcium cycling and signaling in cardiac myocytes. Annu Rev Physiol 2008, 70:23-49.
-
(2008)
Annu Rev Physiol
, vol.70
, pp. 23-49
-
-
Bers, D.M.1
-
3
-
-
84862286538
-
Modulation of cardiac contractility by the phospholamban/SERCA2a regulatome
-
Kranias E.G., Hajjar R.J. Modulation of cardiac contractility by the phospholamban/SERCA2a regulatome. Circ Res 2012, 110:1646-1660.
-
(2012)
Circ Res
, vol.110
, pp. 1646-1660
-
-
Kranias, E.G.1
Hajjar, R.J.2
-
4
-
-
79960787927
-
Phosphatase-1 inhibitor-1 in physiological and pathological beta-adrenoceptor signalling
-
Wittkopper K., Dobrev D., Eschenhagen T., El-Armouche A. Phosphatase-1 inhibitor-1 in physiological and pathological beta-adrenoceptor signalling. Cardiovasc Res 2011, 91:392-401.
-
(2011)
Cardiovasc Res
, vol.91
, pp. 392-401
-
-
Wittkopper, K.1
Dobrev, D.2
Eschenhagen, T.3
El-Armouche, A.4
-
5
-
-
11144307292
-
STRESS signaling pathways that modulate cardiac myocyte apoptosis
-
Baines C.P., Molkentin J.D. STRESS signaling pathways that modulate cardiac myocyte apoptosis. J Mol Cell Cardiol 2005, 38:47-62.
-
(2005)
J Mol Cell Cardiol
, vol.38
, pp. 47-62
-
-
Baines, C.P.1
Molkentin, J.D.2
-
6
-
-
78149478401
-
Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale
-
Rose B.A., Force T., Wang Y. Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale. Physiol Rev 2010, 90:1507-1546.
-
(2010)
Physiol Rev
, vol.90
, pp. 1507-1546
-
-
Rose, B.A.1
Force, T.2
Wang, Y.3
-
7
-
-
33746200175
-
P38 mitogen-activated protein kinase: a future target for heart failure therapy?
-
Kerkela R., Force T. p38 mitogen-activated protein kinase: a future target for heart failure therapy?. J Am Coll Cardiol 2006, 48:556-558.
-
(2006)
J Am Coll Cardiol
, vol.48
, pp. 556-558
-
-
Kerkela, R.1
Force, T.2
-
8
-
-
0037040161
-
P38 mitogen-activated protein kinase mediates a negative inotropic effect in cardiac myocytes
-
Liao P., Wang S.Q., Wang S., Zheng M., Zheng M., Zhang S.J., et al. p38 mitogen-activated protein kinase mediates a negative inotropic effect in cardiac myocytes. Circ Res 2002, 90:190-196.
-
(2002)
Circ Res
, vol.90
, pp. 190-196
-
-
Liao, P.1
Wang, S.Q.2
Wang, S.3
Zheng, M.4
Zheng, M.5
Zhang, S.J.6
-
9
-
-
0034704157
-
Beta 2-adrenergic receptor-induced p38 MAPK activation is mediated by protein kinase A rather than by Gi or gbeta gamma in adult mouse cardiomyocytes
-
Zheng M., Zhang S.J., Zhu W.Z., Ziman B., Kobilka B.K., Xiao R.P. Beta 2-adrenergic receptor-induced p38 MAPK activation is mediated by protein kinase A rather than by Gi or gbeta gamma in adult mouse cardiomyocytes. J Biol Chem 2000, 275:40635-40640.
-
(2000)
J Biol Chem
, vol.275
, pp. 40635-40640
-
-
Zheng, M.1
Zhang, S.J.2
Zhu, W.Z.3
Ziman, B.4
Kobilka, B.K.5
Xiao, R.P.6
-
10
-
-
33746198344
-
Activation of p38 mitogen-activated protein kinase contributes to the early cardiodepressant action of tumor necrosis factor
-
Bellahcene M., Jacquet S., Cao X.B., Tanno M., Haworth R.S., Layland J., et al. Activation of p38 mitogen-activated protein kinase contributes to the early cardiodepressant action of tumor necrosis factor. J Am Coll Cardiol 2006, 48:545-555.
-
(2006)
J Am Coll Cardiol
, vol.48
, pp. 545-555
-
-
Bellahcene, M.1
Jacquet, S.2
Cao, X.B.3
Tanno, M.4
Haworth, R.S.5
Layland, J.6
-
11
-
-
84874425321
-
Unrestrained p38 MAPK activation in Dusp1/4 double-null mice induces cardiomyopathy
-
Auger-Messier M., Accornero F., Goonasekera S.A., Bueno O.F., Lorenz J.N., van Berlo J.H., et al. Unrestrained p38 MAPK activation in Dusp1/4 double-null mice induces cardiomyopathy. Circ Res 2013, 112:48-56.
-
(2013)
Circ Res
, vol.112
, pp. 48-56
-
-
Auger-Messier, M.1
Accornero, F.2
Goonasekera, S.A.3
Bueno, O.F.4
Lorenz, J.N.5
van Berlo, J.H.6
-
12
-
-
78650664278
-
Key roles of endothelin-1 and p38 MAPK in the regulation of atrial stretch response
-
Kerkela R., Ilves M., Pikkarainen S., Tokola H., Ronkainen V.P., Majalahti T., et al. Key roles of endothelin-1 and p38 MAPK in the regulation of atrial stretch response. Am J Physiol Regul Integr Comp Physiol 2011, 300:R140-R149.
-
(2011)
Am J Physiol Regul Integr Comp Physiol
, vol.300
-
-
Kerkela, R.1
Ilves, M.2
Pikkarainen, S.3
Tokola, H.4
Ronkainen, V.P.5
Majalahti, T.6
-
13
-
-
33847038271
-
P38-MAPK induced dephosphorylation of alpha-tropomyosin is associated with depression of myocardial sarcomeric tension and ATPase activity
-
Vahebi S., Ota A., Li M., Warren C.M., de Tombe P.P., Wang Y., et al. p38-MAPK induced dephosphorylation of alpha-tropomyosin is associated with depression of myocardial sarcomeric tension and ATPase activity. Circ Res 2007, 100:408-415.
-
(2007)
Circ Res
, vol.100
, pp. 408-415
-
-
Vahebi, S.1
Ota, A.2
Li, M.3
Warren, C.M.4
de Tombe, P.P.5
Wang, Y.6
-
14
-
-
55949117098
-
Functionally opposing roles of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase in the regulation of cardiac contractility
-
Szokodi I., Kerkela R., Kubin A.M., Sarman B., Pikkarainen S., Konyi A., et al. Functionally opposing roles of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase in the regulation of cardiac contractility. Circulation 2008, 118:1651-1658.
-
(2008)
Circulation
, vol.118
, pp. 1651-1658
-
-
Szokodi, I.1
Kerkela, R.2
Kubin, A.M.3
Sarman, B.4
Pikkarainen, S.5
Konyi, A.6
-
15
-
-
0038095180
-
The MKK6-p38 MAPK pathway prolongs the cardiac contractile calcium transient, downregulates SERCA2, and activates NF-AT
-
Andrews C., Ho P.D., Dillmann W.H., Glembotski C.C., McDonough P.M. The MKK6-p38 MAPK pathway prolongs the cardiac contractile calcium transient, downregulates SERCA2, and activates NF-AT. Cardiovasc Res 2003, 59:46-56.
-
(2003)
Cardiovasc Res
, vol.59
, pp. 46-56
-
-
Andrews, C.1
Ho, P.D.2
Dillmann, W.H.3
Glembotski, C.C.4
McDonough, P.M.5
-
16
-
-
0035834071
-
The in vivo role of p38 MAP kinases in cardiac remodeling and restrictive cardiomyopathy
-
Liao P., Georgakopoulos D., Kovacs A., Zheng M., Lerner D., Pu H., et al. The in vivo role of p38 MAP kinases in cardiac remodeling and restrictive cardiomyopathy. Proc Natl Acad Sci U S A 2001, 98:12283-12288.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 12283-12288
-
-
Liao, P.1
Georgakopoulos, D.2
Kovacs, A.3
Zheng, M.4
Lerner, D.5
Pu, H.6
-
17
-
-
0027497584
-
Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart
-
Ungerer M., Bohm M., Elce J.S., Erdmann E., Lohse M.J. Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart. Circulation 1993, 87:454-463.
-
(1993)
Circulation
, vol.87
, pp. 454-463
-
-
Ungerer, M.1
Bohm, M.2
Elce, J.S.3
Erdmann, E.4
Lohse, M.J.5
-
18
-
-
0033521109
-
Feedback inhibition of G protein-coupled receptor kinase 2 (GRK2) activity by extracellular signal-regulated kinases
-
Pitcher J.A., Tesmer J.J., Freeman J.L., Capel W.D., Stone W.C., Lefkowitz R.J. Feedback inhibition of G protein-coupled receptor kinase 2 (GRK2) activity by extracellular signal-regulated kinases. J Biol Chem 1999, 274:34531-34534.
-
(1999)
J Biol Chem
, vol.274
, pp. 34531-34534
-
-
Pitcher, J.A.1
Tesmer, J.J.2
Freeman, J.L.3
Capel, W.D.4
Stone, W.C.5
Lefkowitz, R.J.6
-
19
-
-
0035958010
-
Phosphorylation of protein phosphatase inhibitor-1 by Cdk5
-
Bibb J.A., Nishi A., O'Callaghan J.P., Ule J., Lan M., Snyder G.L., et al. Phosphorylation of protein phosphatase inhibitor-1 by Cdk5. J Biol Chem 2001, 276:14490-14497.
-
(2001)
J Biol Chem
, vol.276
, pp. 14490-14497
-
-
Bibb, J.A.1
Nishi, A.2
O'Callaghan, J.P.3
Ule, J.4
Lan, M.5
Snyder, G.L.6
-
20
-
-
33745205607
-
Role of calcineurin and protein phosphatase-2A in the regulation of phosphatase inhibitor-1 in cardiac myocytes
-
El-Armouche A., Bednorz A., Pamminger T., Ditz D., Didie M., Dobrev D., et al. Role of calcineurin and protein phosphatase-2A in the regulation of phosphatase inhibitor-1 in cardiac myocytes. Biochem Biophys Res Commun 2006, 346:700-706.
-
(2006)
Biochem Biophys Res Commun
, vol.346
, pp. 700-706
-
-
El-Armouche, A.1
Bednorz, A.2
Pamminger, T.3
Ditz, D.4
Didie, M.5
Dobrev, D.6
-
21
-
-
13644256191
-
A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress
-
Boyce M., Bryant K.F., Jousse C., Long K., Harding H.P., Scheuner D., et al. A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress. Science 2005, 307:935-939.
-
(2005)
Science
, vol.307
, pp. 935-939
-
-
Boyce, M.1
Bryant, K.F.2
Jousse, C.3
Long, K.4
Harding, H.P.5
Scheuner, D.6
-
22
-
-
0032167375
-
Fostriecin, an inhibitor of protein phosphatase 2A, limits myocardial infarct size even when administered after onset of ischemia
-
Weinbrenner C., Baines C.P., Liu G.S., Armstrong S.C., Ganote C.E., Walsh A.H., et al. Fostriecin, an inhibitor of protein phosphatase 2A, limits myocardial infarct size even when administered after onset of ischemia. Circulation 1998, 98:899-905.
-
(1998)
Circulation
, vol.98
, pp. 899-905
-
-
Weinbrenner, C.1
Baines, C.P.2
Liu, G.S.3
Armstrong, S.C.4
Ganote, C.E.5
Walsh, A.H.6
-
23
-
-
33846963541
-
Acute modulation of PP2a and troponin I phosphorylation in ventricular myocytes: studies with a novel PP2a peptide inhibitor
-
Deshmukh P.A., Blunt B.C., Hofmann P.A. Acute modulation of PP2a and troponin I phosphorylation in ventricular myocytes: studies with a novel PP2a peptide inhibitor. Am J Physiol Heart Circ Physiol 2007, 292:H792-H799.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.292
-
-
Deshmukh, P.A.1
Blunt, B.C.2
Hofmann, P.A.3
-
24
-
-
41549160315
-
Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival
-
Junttila M.R., Li S.P., Westermarck J. Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival. FASEB J 2008, 22:954-965.
-
(2008)
FASEB J
, vol.22
, pp. 954-965
-
-
Junttila, M.R.1
Li, S.P.2
Westermarck, J.3
-
25
-
-
0037049977
-
Cardiac excitation-contraction coupling
-
Bers D.M. Cardiac excitation-contraction coupling. Nature 2002, 415:198-205.
-
(2002)
Nature
, vol.415
, pp. 198-205
-
-
Bers, D.M.1
-
26
-
-
84870241098
-
Altered sarcoplasmic reticulum calcium cycling-targets for heart failure therapy
-
Kho C., Lee A., Hajjar R.J. Altered sarcoplasmic reticulum calcium cycling-targets for heart failure therapy. Nat Rev Cardiol 2012, 9:717-733.
-
(2012)
Nat Rev Cardiol
, vol.9
, pp. 717-733
-
-
Kho, C.1
Lee, A.2
Hajjar, R.J.3
-
27
-
-
0022921924
-
Sequence analysis of phospholamban. Identification of phosphorylation sites and two major structural domains
-
Simmerman H.K., Collins J.H., Theibert J.L., Wegener A.D., Jones L.R. Sequence analysis of phospholamban. Identification of phosphorylation sites and two major structural domains. J Biol Chem 1986, 261:13333-13341.
-
(1986)
J Biol Chem
, vol.261
, pp. 13333-13341
-
-
Simmerman, H.K.1
Collins, J.H.2
Theibert, J.L.3
Wegener, A.D.4
Jones, L.R.5
-
28
-
-
67650710788
-
Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology
-
Nicolaou P., Hajjar R.J., Kranias E.G. Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology. J Mol Cell Cardiol 2009, 47:365-371.
-
(2009)
J Mol Cell Cardiol
, vol.47
, pp. 365-371
-
-
Nicolaou, P.1
Hajjar, R.J.2
Kranias, E.G.3
-
29
-
-
0036261564
-
Type 1 phosphatase, a negative regulator of cardiac function
-
Carr A.N., Schmidt A.G., Suzuki Y., del MF Sato Y., Lanner C., et al. Type 1 phosphatase, a negative regulator of cardiac function. Mol Cell Biol 2002, 22:4124-4135.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 4124-4135
-
-
Carr, A.N.1
Schmidt, A.G.2
Suzuki, Y.3
Del, M.F.4
Sato, Y.5
Lanner, C.6
-
30
-
-
20244377242
-
Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase 1
-
Pathak A., del Monte F., Zhao W., Schultz J.E., Lorenz J.N., Bodi I., et al. Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase 1. Circ Res 2005, 96:756-766.
-
(2005)
Circ Res
, vol.96
, pp. 756-766
-
-
Pathak, A.1
del Monte, F.2
Zhao, W.3
Schultz, J.E.4
Lorenz, J.N.5
Bodi, I.6
-
31
-
-
1642388834
-
PKC-alpha regulates cardiac contractility and propensity toward heart failure
-
Braz J.C., Gregory K., Pathak A., Zhao W., Sahin B., Klevitsky R., et al. PKC-alpha regulates cardiac contractility and propensity toward heart failure. Nat Med 2004, 10:248-254.
-
(2004)
Nat Med
, vol.10
, pp. 248-254
-
-
Braz, J.C.1
Gregory, K.2
Pathak, A.3
Zhao, W.4
Sahin, B.5
Klevitsky, R.6
-
32
-
-
76649092318
-
Constitutively active phosphatase inhibitor-1 improves cardiac contractility in young mice but is deleterious after catecholaminergic stress and with aging
-
Wittkopper K., Fabritz L., Neef S., Ort K.R., Grefe C., Unsold B., et al. Constitutively active phosphatase inhibitor-1 improves cardiac contractility in young mice but is deleterious after catecholaminergic stress and with aging. J Clin Invest 2010, 120:617-626.
-
(2010)
J Clin Invest
, vol.120
, pp. 617-626
-
-
Wittkopper, K.1
Fabritz, L.2
Neef, S.3
Ort, K.R.4
Grefe, C.5
Unsold, B.6
-
33
-
-
2442647676
-
Essential role of troponin I in the positive inotropic response to isoprenaline in mouse hearts contracting auxotonically
-
Layland J., Grieve D.J., Cave A.C., Sparks E., Solaro R.J., Shah A.M. Essential role of troponin I in the positive inotropic response to isoprenaline in mouse hearts contracting auxotonically. J Physiol 2004, 556:835-847.
-
(2004)
J Physiol
, vol.556
, pp. 835-847
-
-
Layland, J.1
Grieve, D.J.2
Cave, A.C.3
Sparks, E.4
Solaro, R.J.5
Shah, A.M.6
-
34
-
-
0024246121
-
Kinetic and equilibrium characterization of an energy-transducing enzyme and its partial reactions
-
Inesi G., Kurzmack M., Lewis D. Kinetic and equilibrium characterization of an energy-transducing enzyme and its partial reactions. Methods Enzymol 1988, 157:154-190.
-
(1988)
Methods Enzymol
, vol.157
, pp. 154-190
-
-
Inesi, G.1
Kurzmack, M.2
Lewis, D.3
|