Aflatoxin B1 disrupts the androgen biosynthetic pathway in rat Leydig cells

Food and Chemical Toxicology

Volumn 65, Issue , 2014, Pages 252-259

  Adedara, Isaac A ^a,b   Nanjappa, Manjunatha K ^a   Farombi, Ebenezer O ^b   Akingbemi, Benson T ^a  

^a AUBURN UNIVERSITY   (United States)

^b UNIVERSITY OF IBADAN   (Nigeria)

Author keywords

Mycotoxin; Rats; Testis; Testosterone; Toxicology

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; AFLATOXIN B1; ANDROGEN; MITOGEN ACTIVATED PROTEIN KINASE P38; STEROIDOGENIC ACUTE REGULATORY PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TESTOSTERONE; TESTOSTERONE 17BETA DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOPROTEIN; UO 126; MYCOTOXIN;

ANDROGEN SYNTHESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ISOLATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; LEYDIG CELL; LONG EVANS RAT; MALE; MALE FERTILITY; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; RAT; SEX HORMONE DETERMINATION; TESTOSTERONE RELEASE; TESTOSTERONE SYNTHESIS; CONTROLLED STUDY; DIETARY INTAKE; LIVER TOXICITY; PROTEIN ANALYSIS; RADIOIMMUNOASSAY; RATTUS NORVEGICUS; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CELL CULTURE; DRUG EFFECT; METABOLISM; TESTIS; TOXICOLOGY;

RATTUS;

MYCOTOXIN; RATS; TESTIS; TESTOSTERONE; TOXICOLOGY;

AFLATOXIN B1; ANDROGENS; ANIMALS; CELLS, CULTURED; LEYDIG CELLS; MALE; RADIOIMMUNOASSAY; RATS; RATS, LONG-EVANS;

EID: 84892873652     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.12.027     Document Type: Article

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