The ERK Signaling Cascade Inhibits Gonadotropin-stimulated Steroidogenesis

Journal of Biological Chemistry

Volumn 276, Issue 17, 2001, Pages 13957-13964

  Seger, Rony ^a   Hanoch, Tamar ^a   Rosenberg, Revital ^a   Dantes, Ada ^a   Merzt, Wolfgang E ^b   Strauss III, Jerome F ^c   Amsterdam, Abraham ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYMES; GENES;

STEROIDOGENESIS;

HORMONES;

CYCLIC AMP DEPENDENT PROTEIN KINASE; FOLLITROPIN; GONADOTROPIN; LUTEINIZING HORMONE; MITOGEN ACTIVATED PROTEIN KINASE; STEROIDOGENIC ACUTE REGULATORY PROTEIN; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CHORIONIC GONADOTROPIN; CYCLIC AMP; ENZYME INHIBITOR; FLAVONOID; FORSKOLIN; PHOSPHOPROTEIN; PROGESTERONE; STEROID;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENETIC TRANSFECTION; GRANULOSA CELL; NONHUMAN; PLASMID; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STEROIDOGENESIS; WESTERN BLOTTING; ANIMAL; BIOLOGICAL MODEL; BIOSYNTHESIS; CELL LINE; DOSE RESPONSE; DOWN REGULATION; ENZYME ACTIVATION; FEMALE; FLUORESCENCE MICROSCOPY; HUMAN; METABOLISM; PHOSPHORYLATION; PROTEIN BINDING; RAT; TIME;

ANIMALIA;

ANIMALS; CELL LINE; CHORIONIC GONADOTROPIN; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME ACTIVATION; ENZYME INHIBITORS; FEMALE; FLAVONOIDS; FOLLICLE STIMULATING HORMONE; FORSKOLIN; GONADOTROPINS; GRANULOSA CELLS; HUMANS; LUTEINIZING HORMONE; MAP KINASE SIGNALING SYSTEM; MICROSCOPY, FLUORESCENCE; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; PHOSPHOPROTEINS; PHOSPHORYLATION; PLASMIDS; PROGESTERONE; PROTEIN BINDING; RATS; SIGNAL TRANSDUCTION; STEROIDS; TIME FACTORS; TRANSFECTION;

EID: 0035958046     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M006852200     Document Type: Article

References (52)

1. Sprengel, R., Braun, T., Nikolics, K., Segaloff, D. L., and Seeburg, P. H. (1990) Mol Endocrinol 4, 525-530
2. Amsterdam, A., Plehn-Dujowich, D., and Suh, B. S. (1992) Biol. Reprod. 46, 513-522
3. Segaloff, D. L., and Ascoli, M. (1993) Endocr. Rev. 14, 324-347
4. Amsterdam, A., and Selvaraj, N. (1997) Endocr. Rev. 18, 435-461
5. Cooke, B. A. (1999) Mol. Cell. Endocrinol. 151, 25-35
6. Stocco, D. M. (2000) J. Endocrinol. 164, 247-253
7. Strauss, J. F., III, Kallen, C. B., Christensen, L. K., Watari, H., Devoto, L., Arakane, F., Kiriakidou, M., and Sugawara, T. (1999) Recent Prog. Horm. Res. 54, 369-394
8. Amsterdam, A., Gold, R. S., Hosokawa, K., Yoshida, Y., Sasson, R., Jung, Y., and Kotsuji, F. (1999) Trends Endocrinol. 10, 255-262
9. Amsterdam, A., Berkowitz, A., Nimrod, A., and Kohen, F. (1980) Proc. Natl. Acad. Sci. U. S. A. 77, 3440-3444
10. Seger, R., and Krebs, E. G. (1995) FASEB. J. 9, 726-735
11. Lewis, T. S., Shapiro, P. S., and Ahn, N. G. (1998) Adv. Cancer Res. 74, 49-139
12. Cameron, M. R., Foster, J. S., Bukovsky, A., and Wimalasena, J. (1996) Biol. Reprod. 55, 111-119
13. Das, S., Maizels, E. T., DeManno, D., St. Clair, E., Adam, S. A., and Hunzicker-Dunn, M. (1996) Endocrinology 137, 967-974
14. Amsterdam, A., and Rotmensch, S. (1987) Endocr. Rev. 8, 309-337
15. Merz, W. E. (1988) Biochem. Biophys. Res. Commun. 156, 1271-1278
16. Pollack, S. E., Furth, E. E., Kallen, C. B., Arakane, F., Kiriakidou, M., Kozarsky, K. F., and Strauss, J. F., III (1997) J. Clin. Endocrinol. Metab. 82, 4243-4251
17. Suh, B. S., Sprengel, R., Keren-Tal, I., Himmelhoch, S., and Amsterdam, A. (1992) J. Cell Biol. 119, 439-450
18. Keren-Tal, I., Dantes, A., Sprengel, R., and Amsterdam, A. (1993) Mol. Cell. Endocrinol. 95, R1-R10
19. Yung, Y., Yao, Z., Hanoch, T., and Seger, R. (2000) J. Biol. Chem. 256, 15799-15808
20. Day, R. N., Walder, J. A., and Maurer, R. A. (1989) J. Biol. Chem. 264, 431-436
21. Rubinfeld, H., Hanoch, T., and Seger, R. (1999) J. Biol. Chem. 274, 30349-30352
22. Aharoni, D., Meiri, I., Atzmon, R., Vlodavsky, I., and Amsterdam, A. (1997) Curr. Biol. 7, 43-51
23. Naor, Z., Benard, O., and Seger, R. (2000) Trends Endocrinol. Metab. 11, 91-99
24. Yung, Y., Dolginov, Y., Yao, Z., Rubinfeld, H., Michael, D., Hanoch, T., Roubini, E., Lando, Z., Zharhary, D., and Seger, R. (1997) FEBS Lett. 408, 292-296
25. van Loenen, H. J., van Gelderen-Boele, S., Flinterman, J. F., Merz, W. E., and Rommerts, F. F. (1995) J. Endocrinol. 147, 367-375
26. Sugawara, T., Kiriakidou, M., McAllister, J. M., Holt, J. A., Arakane, F., and Strauss, J. F., III (1997) Steroids 62, 5-9
27. Seger, R., Biener, Y., Feinstein, R., Hanoch, T., Gazit, A., and Zick, Y. (1995) J. Biol. Chem. 270, 28325-28330
28. Clark, B. J., Combs, R., Hales, K. H., Hales, D. B., and Stocco, D. M. (1997) Endocrinology 138, 4893-4901
29. Favata, M. F., Horiuchi, K. Y., Manos, E. J., Daulerio, A. J., Stradley, D. A., Feeser, W. S., Van Dyk, D. E., Pitts, W. J., Earl, R. A., Hobbs, F., Copeland, R. A., Magolda, R. L., Scherle, P. A., and Trzaskos, J. M. (1998) J. Biol. Chem. 273, 18623-18632
30. Arakane, F., Kallen, C. B., Watari, H., Foster, J. A., Sepuri, N. B., Pain, D., Stayrook, S. E., Lewis, M., Gerton, G. L., and Strauss, J. F., III (1998) J. Biol. Chem. 273, 16339-16345
31. Hanukoglu, L., Suh, B. S., Himmelhoch, S., and Amsterdam, A., (1990) J. Cell Biol. 111, 1373-1381
32. Sugawara, T., Lin, D., Holt, J. A., Martin, K. O., Javitt, N. B., Miller, W. L., and Strauss, J. F., III (1995) Biochemistry 34, 12506-12512
33. de Rooij, J., Zwartkruis, F. J., Verheijen, M. H., Cool, R. H., Nijman, S. M., Wittinghofer, A., and Bos, J. L. (1998) Nature 396, 474-477
34. Bornfeldt, K. E., and Krebs, E. G. (1999) Cell Signal. 11, 465-477
35. Wu, J., Dent, P., Jelinek, T., Wolfman, A., Weber, M. J., and Sturgill, T. W. (1993) Science 262, 1065-1069
36. Graves, L. M., Bornfeldt, K. E., Raines, E. W., Potts, B. C., Macdonald, S. G., Ross, R., and Krebs, E. G. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 10300-10304
37. Cook, S. J., and McCormick, F. (1993) Science 262, 1069-1072
38. Zhou, T. H., Ling, K., Guo, J., Zhou, H., Wu, Y. L., Jing, Q., Ma, L., and Pei, G. (2000) J. Biol. Chem. 275, 2513-2519
39. Gutkind, J. S. (1998) Oncogene 17, 1331-1342
40. Yao, H., York, R. D., Misra-Press, A., Carr, D. W., and Stork, P. J. (1998) J. Biol. Chem. 273, 8240-8247
41. Yamaguchi, T., Pelling, J. C., Ramaswamy, N. T., Eppler, J. W., Wallace, D. P., Nagao, S., Rome, L. A., Sullivan, L. P., and Grantham, J. J. (2000) Kidney Int. 57, 1460-1471
42. Silverman, M. A., Benard, O., Jaaro, H., Rattner, A., Citri, Y., and Seger, R. (1999) J. Biol. Chem. 274, 2631-2636
43. Selvaraj, N., Israeli, D., and Amsterdam, A. (1996) Mol. Cell. Endocrinol. 123, 171-177
44. Kiriakidou, M., McAllister, J. M., Sugawara, T., and Strauss, J. F., III (1996) J. Clin. Endocrinol. Metab. 81, 4122-4128
45. Zazopoulos, E., Lalli, E., Stocco, D. M., and Sassone-Corsi, P. (1997) Nature 390, 311-315
46. Lalli, E., Melner, M. H., Stocco, D. M., and Sassone-Corsi, P. (1998) Endocrinology 139, 4237-4243
47. Stocco, D. M. (1998) Rev. Reprod. 3, 82-85
48. Hammer, G. D., Krylova, I., Zhang, Y., Darimont, B. D., Simpson, K., Weigel, N. L., and Ingraham, H. A. (1999) Mol. Cell 3, 521-526
49. Yamamoto, N., Hegde, A. N., Chain, D. G., and Schwartz, J. H. (1999) J. Neurochem. 73, 2415-2423
50. Pitcher, J. A., Tesmer, J. J., Freeman, J. L., Capel, W. D., Stone, W. C., and Lefkowitz, R. J. (1999) J. Biol. Chem. 274, 34531-34534
51. Ferrell, J. E., Jr. (1996) Trends Biochem. Sci. 21, 460-466
52. Zeleznik, A. J., and Somers, J. P. (1999) Trends Endocrinol. Metab. 10, 189-193